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Biomedical subjects

A Ferro

Publications and source records attributed to A Ferro.

At least 109 records · Page 6Linked to original sources
PubMed1989

[Prevalence of antibodies against HIV in drug addicts and convicts].

The presence of anti-HIV (human immunodeficiency virus) antibodies was determined in 325 subjects. The samples were taken from 138 convicts from Carabanchel and Ocaña I jail, 162 parenteral drug addicts (PDA) from a center for rehabilitation of drug addicts (CR), and from 14 family members and 11 stable couples of these PDAs. There was a global seroprevalence of 61.23%, 56.9% in Carabanchel, 68.7% in Ocaña I and 68.5% in the CR. When the results from the jailed convicts were analyzed according to risk factors, it was discovered that drug addiction was the most relevant since there was only a 29.4% of seropositivity in non PDAs with a statistically significant difference (p less than 0.01). This value was also higher than the seroprevalence found in the CR with a statistically significant difference (p less than 0.01). None of the family members of the CR were HIV-positive. Two stable couples were positive in this sexual contact group. This article makes clear the important role of drug addiction in the dispersion of HIV infection in our midst.

Adolescent↗
PubMed1987

Kinetic evidence for thermally induced conformational change of butyrylcholinesterase.

The effect of temperature on the kinetics of human plasma butyrylcholinesterase-catalyzed reactions was studied. The Arrhenius plot of o-nitrophenylbutyrate hydrolysis presents a break at 21 degrees C. However, nucleophilic competition data indicate that there is no change in the rate-limiting step of the overall reaction. In addition, the temperature dependence of the bimolecular rate constant of enzyme carbamylation shows a break at 18 degrees C. These results argue for the existence of thermally induced conformational active states of the enzyme tetramer. It is suggested that the effects of this transition on kinetics arise at the acylation step.

Acylation↗