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Biomedical subjects

A Ferlito

Publications and source records attributed to A Ferlito.

At least 181 records · Page 10Linked to original sources
PubMed1978

Bilateral synchronous trabecular adenocarcinoma of the parotid gland.

This report deals with a rare case of bilateral cancer of the parotid gland, with lymph node metastases. Histologically, the tumor was a trabecular adenocarcinoma. The first neoplasm was located in the right parotid gland and developed into a pleomorphic adenoma. Both cancers were treated with parotidectomy and bilateral neck dissection. From a comprehensive review of the literature, it appears that the present case is the sixth on record of bilateral parotid tumors. Pathogenetically, it is suggested that a common carcinogenic factor might have acted simultaneously and bilaterally on the parotid gland.

Adenocarcinoma↗
PubMed1978

Primary pleomorphic liposarcoma of the larynx.

Liposarcoma is a rare tumor in the larynx. A case of such lesion occurring in a 52 year old male patient is described. This is the second case to be reported in the world literature. The patient underwent hemilaryngectomy and later total laryngectomy for a recurrent tumor and is living and well six years after diagnosis.

Humans↗
PubMed1977

Primary lymphoepithelial carcinoma of the hypopharynx.

Lymphoepithelial carcinoma (lymphoepithelioma) is a neoplasm that may be found in nasopharynx, nasal fossae, maxillary sinus, base of the tongue, tonsil, thymus and parapharyngeal area. Such a tumor is extremely rare in the hypopharynx and the case described is the second so far reported in the world literature, after the first case by Dockerty et al. (1968). The tumor is morphologically identical to those arising in other organs. Our patient died ten months after diagnosis.

Carcinoma, Squamous Cell↗
PubMed1977

'Malignant lymphoepithelial lesions' (undifferentiated ductal carcinomas of the parotid gland). Three case reports and review of the literature.

Three cases of the so-cassed malignant lymphoepithelial lesion occurring in women are described. The authors, however, prefer to label the lesion 'undifferentiated carcinoma of the parotid'. From an accurate review of the world literature it appears that 23 cases of such lesion have been reported, 22 arising in the parotid and 1 in the submandibular gland. The malignant lymphoepithelial lesion has been mainly encountered in Eskimos and the three cases of the present report are the first to have been evidenced in Europe. The malignant lymphoepithelial lesion is discussed from the taxonomic, nosologic, pathogenetic, diagnostic and therapeutic points of view. The lesion does not seem to be of an autoimmune nature, unlike the benign lymphoepithelial lesion which is generally regarded as an autoimmune disease.

Adult↗
PubMed1976

Benign mixed tumour of heterotopic salivary gland tissue in upper neck. Report of a case with a review of the literature on heterotopic salivary gland tissue.

A case of benign mixed tumour arising in ectopic salivary gland tissue of the mucous type is described. The tumour was located at the angle of the right mandible, in the upper middle third of the neck, along the anterior border of the sternomastoid muscle. This observation is substantiated by a pathomorphological study. A comprehensive review of the world literature on heteroptic salivary gland tissue has also been carried out, together with a search of the possible pathogenesis which seems to be connected with an anomalous embryonic development within the branchial apparatus.

Adenoma, Pleomorphic↗
PubMed1976

Primary anaplastic giant cell adenocarcinoma of the larynx.

Anaplastic giant cell adenocarcinoma is an extremely rare tumour arising in the bronchial mucosa. This report describes an example--the first to be reported--of such a tumour evidenced in the subglottic region in a 64-year-old man. Histologically, the tumour resembles that arising in the lung and its morphological characteristics justify a distinction of anaplastic giant cell adenocarcinoma from other types of laryngeal malignant epithelial tumours. As to its histogenesis, the neoplasm is most probably of glandular origin and should be considered as a dedifferentiated adenocarcinoma. The patient, who had undergone total laryngectomy followed by X-ray treatment, is alive one year after surgery.

Adenocarcinoma↗
PubMed1976

Histological appearances and nuclear DNA content of verrucous squamous cell carcinoma of the larynx.

Of the 12 cases of verrusous squamous cell carcinoma of the larynx encountered since 1968 at the Department of Otolaryngology of Padua University (including the Verona Section) and the Department of Pathologic Anatomy of the University of Trieste, three are reported, together with an investigation of the nuclear DNA content of the tumour cells. It is suggested that such a study may assit with early detection of verrucous carcinoma. The laryngeal localization of the neoplasm has been evidenced only in some centres. The difficulties in establishing a correct diagnosis for this variant of squamous cell carcinoma are emphasized and the pathomorphological features, as well as the microscopic and macroscopic appearances, are discussed. The prognosis is excellent and the therapy of choice must be only surgical, as radiation has not only proven ineffective, but in some cases has induced anaplasia, leading to a rapid dissemination of the tumour.

Aged↗
PubMed1976

Primary cancer of the larynx associated with primary lung cancer. Report of 21 cases, 14 with autopsy findings and 7 biopsies.

The present paper reports 21 cases (14 autopsies and 7 biopsies) of associated primary cancers of the larynx and the lung. This association is by no means uncommon, the laryngeal lesion being usually the first to appear. Mulitple primary cancers--of the same or of a different histologic type--tend to occur in the same organ or organ system, either simultaneously or after a time interval. In case of synchronous primary malignant tumour of the larynx and lung the most lethal cancer (the lung cancer) must be managed first. Cancer patients are more likely than other individuals to develop a second primary malignant tumour. Laryngectomized patients should be followed-up possibly by means of cytologic examinations of bronchial secretions and chest X-rays at short intervals for early detection of a possible second primary malignant pulmonary lesion.

Adult↗
PubMed1976

A pathologic and clinical study of adenosquamous carcinoma of the larynx. Report of four cases and review of the literature.

Four cases of adenosquamous carcinoma are described. Emphasis is put on the rarity of this histological type of tumour which was first described in the larynx by Gerughty et al. (1968) who reported three cases. An exhaustive histological documentation of the neoplasm accompanies the discussion of its pathomorphological characteristics, histogenesis, differential diagnosis, prognosis and treatment. Stress is laid on the extreme aggressiveness of the neoplasm and on its high biologic malignancy. Elective treatment is radical surgery. The tumour in question is a distinct anatomo-clinical entity with its own connotations and therefore must be distinguished from the most common squamous cell carcinoma of the larynx.

Aged↗
PubMed1975

Rhabdomyoma purum of the larynx.

A case of pure well-differentiated rhabdomyoma of the larynx occurring in a 50-year-old male is reported. The lesion was localized to the interarytenoid region. From an accurate revision of the world literature on the subject it appears that the cases so far described number only seven, including the one in the present report. Furthermore, the differential histological and histochemical criteria for distinguishing rhabdomyoma from granular cell Schwannoma are discussed and tabulated, as the two neoplasms may be easily confused. In our case, there has been no evidence of recurrence of the tumour for more than 1 year, which is in accordance with the previous cases reported in the literature.

Adult↗
PubMed1975

Heterotopic gastric mucosa of the tongue and the oesophagus.

A case of gastric heterotopia of the tongue and one of heterotopic gastric mucosa of the oesophagus are described. From a comprehensive review of the world literature it appears that the present case of lingual gastric heterotopia is only the eighth so far reported and the first occurring in a woman. The site of the polypoid formation medially in the body of the tongue and its presence since birth indicate a congenital malformation. As to the observation of heterotopic gastric mucosa in the oesophagus, it is worth noting that the aberrant tissue was located in a wide area between two sites of squamous carcinoma of the oesophagus. Primary adenocarcinoma of the upper third of the oesophagus is extremely rare and its histogenesis becomes even more controversial when consideration is given to some of the features of the case presented. In particular, the hypothesis that adenocarcinoma may arise from heterotopic gastric epithelium is doubtful and does not explain the origin of all adenocarcinomas in the upper third of the oesophagus. The assumption that it may arise from oesophageal glands and/or from tracheobranchial rests remains well-founded.

Adult↗