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Biomedical subjects

A Fantoni

Publications and source records attributed to A Fantoni.

At least 109 records · Page 6Linked to original sources

Mouse foetal development: translational inactivation of globin genes during the terminal differentiation of yolk sac erythroid cells.

The molecular mechanism of globin genes inactivation has been explored at the translational level in yolk sac erythroid cells from mouse foetuses. Ageing of the messenger molecules is paralleled by a progressive decrease of the poly(A) tail. Poly(A) less messengers are less active when tested in a wheat germ cell free system and become uncapable to terminate globin chain elongation.

Age Factors↗

[Association of adult obese-type diabetes and depressive psychosis (clinical cases)].

The conception of a specific association between maturity-onset diabetes and manic-depressive psychosis, on a common basis with diencephalic functional obesity, has been recently taken again in consideration by the psychiatric literature. Investigations on this problem from diabetological point of view have been so far completely lacking, and are proposed with the present study. Symptomatic depressive conditions in diabetes are frequent and should be primarily separated from depressive endogenous psychosis. The pathogenesis of the association between diabetes of the adult-obese type and psychosis might be discussed according to a transactional theoretical model, assuming a positive feed-back mechanism of the two relationships: diabetes-psychosis and psychosis-diabetes. With these criteria, 4 observations of the clinical association were collected out of 274 admissions for diabetes, during 1976. Diabetes is intended as overt diabetes; obesity presented with the stenic picture; psychosis had a monopolar melancholic course. Similar clinical features were characteristic in all cases. The relationship diabetes-psychosis showed no evidence, unless importance should be given to a potential diabetes in 3 cases. On the contrary, the relationship psychosis-diabetes could be demonstrated in the four cases. A psychosomatic scheme connecting the neuro-hormonal correlations to a genetically conditioned exhaustion of the beta-function, is postulated. During melancholic recurrences, diabetes proved to be insulin-dependent and even insulin-resistent in 2 cases. Tricyclic antidepressant theraphy did not modify the metabolic situation.

Adult↗

[Description of bilateral hydrocele of the canal of Nück. Clinical case].

A case of Nück's hydrocele is described. Hydrocele is not a rare condition but is often incorrectly diagnosed as a cyst or abscess of Bartolino's gland. It is vital to ascertain the presence of an external oblique inguinal hernia which has the same pathogenesis. This association occurs in 30-40% of hydrocele cases.

Adnexal Diseases↗