Chromosomes of the zebra fish. A model for cytogenetic, embryologic, and ecologic study.
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Animals↗
Biomedical subjects
A Endo
Publications and source records attributed to A Endo.
Responses of plasma catecholamines, renin-angiotensin-aldosterone system, and atrial natriuretic peptide to exercise in patients with essential hypertension.
Neurohormonal responses to exercise have not been studied fully in patients with essential hypertension (HT). This study determined if neurohormonal responses to exercise are altered between three subgroups of HT categorized by basal plasma renin activity (PRA). Plasma norepinephrine, epinephrine, atrial natriuretic peptide (ANP), PRA, angiotensin II (AII), and aldosterone were measured at rest and after submaximal treadmill exercise in 39 patients with essential HT (WHO classes I-II) and 13 controls. Patients with HT were divided into three subgroups based on the PRA level [low-renin (< 0.5) HT (n = 14), normal-renin (0.5-2.0) HT (n = 13), and high-renin (> 2.0) HT (n = 12)]. Patients with HT had higher blood pressure during exercise compared to controls, but blood pressure responses were similar among low-, normal-, and high-renin HT. Neurohormonal factors were comparable between all hypertensives and controls, except for higher plasma AII at rest in patients with HT. When neurohormones were compared among three subgroups of HT, plasma norepinephrine and epinephrine responses were similar. Patients with high-renin HT had higher PRA and AII, and lower ANP levels at rest and after exercise. In all hypertensives, negative correlations were observed between resting PRA and resting ANP (r = -0.41, p < 0.01), as well as peak PRA and peak ANP (r = -0.33, p < 0.05). Thus, neurohormonal responses to exercise varied with similar cardiac responses among subgroups of essential HT stratified according to renin levels. Patients with high-renin HT had augmented renin-angiotensin system activity with a decrease in ANP levels both at rest and after exercise. A reciprocal relationship between renin-angiotensin system activity and ANP was observed both at rest and after exercise in HT.
Adult↗
Design and development of an expert system to assist diagnosis and treatment of chronic hepatitis using traditional Chinese medicine.
The treatment of chronic hepatitis with traditional Chinese medicine shows good therapeutic effectiveness in clinical practice. Since the process for the diagnosis in Chinese medicine is quite different from that of modern Western medicine, many physicians of modern medicine cannot practise it readily and effectively. We describe an expert system designed to support physicians who may not be familiar with the domain of traditional Chinese medicine, to treat chronic hepatitis by using Chinese medicine. This system was developed by logic programming language PROLOG, where the knowledge of Chinese medicine is represented in a semantic network structure and the reasoning strategy is based on the hypothesize-and-test approach. This system can guide the user to collect patient information easily, and based on those items of information this leads to the possible diagnosis and treatment for chronic hepatitis using Chinese medicine. The results of this system are compared with 40 patient case records and analysed by a specialist in Chinese medicine.
Artificial Intelligence↗
Esophageal reflux after gastrectomy: a hazard after Billroth-I subtotal gastrectomy.
One hundred and seventy-six patients were evaluated for esophageal reflux after gastrectomy. Apart from proximally and totally gastrectomized cases, the conventional Billroth-I type of distal subtotal gastrectomy destroys many esophageal reflux preventive mechanisms. The Roux-en-Y type of repair should be adopted for the prevention of reflux.
Esophagus↗