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Biomedical subjects

A Ehrlich

Publications and source records attributed to A Ehrlich.

At least 55 records · Page 3Linked to original sources

The dual effects of aluminum as activator and inhibitor of adenylate cyclase in the liver fluke Fasciola hepatica.

The liver fluke, Fasciola hepatica, has a very active adenylate cyclase which can be stimulated by NaF or by serotonin and guanine nucleotides. Micromolar amounts of AlCl3 augment the activation by F-. In contrast, when the enzyme is activated with serotonin and guanine nucleotides, AlCl3 inhibits the activation. Aluminum also inhibits the activation by forskolin. Gallium mimics the effects of aluminum.

Adenylyl Cyclase Inhibitors↗

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