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Biomedical subjects

A Doenicke

Publications and source records attributed to A Doenicke.

At least 145 records · Page 8Linked to original sources
PubMed1975

[Histamine liberation in man following plasma substitution with gelatine and dextran: cause of anaphylactic reactions in the hospital?].

After rapid gelatin infusion in many cases a release of relatively small amounts of histamine was observed. Clinical symptoms occured in 5 cases in correspondence to the increased histamine levels, but were relatively harmless. The application of dextran 60 induced anaphylactoid reactions in 2 persons, with death in one case. Plasma histamine level were normal in both cases. Histamine release probably is not the cause of dextrn induced anaphylactoid reactions.

Anaphylaxis↗
PubMed1975

[Plasma histamine levels in man following infusion of hydroxyethyl starch: a contribution to the question of allergic or anaphylactoid reactions following administration of a new plasma substitute (author's transl)].

In contrast to the effects of rapid infusion of gelatin and dextran preparations, no histamine release was observed in 10 human subjects (volunteers) following rapid infusion of hydroxyethyl starch. This was measured by fluorometric histamine determination in venous plasma. Furthermore no clinical symptoms of an allergic or anaphylactoid reaction could be detected in any of the volunteers.

Adult↗