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Biomedical subjects

A Dimitrov

Publications and source records attributed to A Dimitrov.

At least 109 records · Page 6Linked to original sources
PubMed1996

[The outcome of pregnancy and labor after a period of sterility].

In a retrospective study is examine the effect of a previous state of sterility on the outcome of pregnancy and labor. For two years (1993-1994) there were 203 (2.6%) women who gave birth after 6.7% +/- 3.5 years of sterility. From the study are excluded 9 women (4.4%) with multifetal pregnancies and 13 cases (6.4%) with different diseases, which may adversely affect the pregnancy of the foetus. In the study group of 181 primiparous women the rate of premature labor is 2.2% which is significantly lower than the hospital incidence (11%) for the same period. The cesarean section (CS) rate after period of sterility is unreasonably high--69%. In the subgroup scheduled for vaginal labor CS are performed in 34% of cases. The indications for the elective CS are complex, less justifiable and partially due to non medical reasons. The past period of sterility has not adverse effect on the course of the vaginal labor or the state of the newborn at delivery.

Adult↗
PubMed1996

[The effect of the woman's age on the course of pregnancy and labor in breech presentation].

The influence of woman's age on pregnancy outcome and delivery of 362 cases of pregnancies in breech presentation was studied retrospectively. The cases are distributed in 6 interval groups of 5 years each and are compared to the data of vertex presentation. The rate of antedated and pregnancy induced diseases are the same in breech and vertex presentation and do not depend on the type of presentation. There is an increase of premature breech deliveries with the decrease of woman's age. The frequency of Cesarean sections is increased with the woman's age, especially after the thirties. The ruptures of the soft birth canal and the need of oxytocin stimulation are increases with woman's age. In case of selected and successive breech labor the state of the newborn does not depend on the woman's age.

Adult↗
PubMed1996

[The effect of fetal maturity and the delivery method on fetal status in breech presentation].

In a retrospective study of 363 pregnancies with one foetus in breech presentation is evaluated the effect of foetal maturity and the route of delivery on the state of the newborn, assessed by the 5 min. Apgar score. The cases are allocated in subgroups according the foetal weight and height, gestational week and the route of delivery. The results show 37% small for gestational age in the subgroup with low birth weight (1500-2500 g). From the group with low weight SGA sustain better the labor and delivery than the eutrophic. The term newborn in breech presentation are with higher Apgar score than delivered by cesarean section. In the group of newborn with low weight the route of delivery has not effect on the Apgar score. The estimated weight and gestational week should be taken in account than managing breech labor.

Adult↗
PubMed1996

[The side effects of the prevention of blood loss in the placental period].

On the base of 192 retrospective and 144 prospective cases are evaluated the side of routine prophylactic of the blood loss at the third period of labor. The control group consist of 50 labouring women with expective management of placental period. In normotensive women the methergine does not increase the blood pressure. The use of oxytocic drugs after the delivery of the head shorten the time of placental separation but make more difficult the cord traction method for the delivery of the placenta. The active management of the placental period decrease the rate of instrumental revision of the uterine cavity and the supplemental administration of oxytocic in the early postpartum period. This investigation confirms and justify the routine use of oxytocic after the delivery of the head as a prophylactic of the blood loss in the placental period.

Analysis of Variance↗
PubMed1996

[Blood loss in the placental period in relation to the type of prophylaxis].

The aim of this study is to asses the blood loss in third period of labor according the method of its prophylactic. The material consist of 144 prospective and 192 retrospective cases. The blood loss is assessed visually and after that it is weighted. Up to the delivery of placenta the visually assessed blood loss is insignificantly greater than the weighted one. All cases are subdivided in three groups according the management of third period: -with methergin, with oxytocin and without uterostonic. The blood loss associated with the separation and delivery of the placenta is not different in the groups, but the early postpartum haemorrhage is significantly greater in the cases without uterostonics for the delivery of placenta. In premature labors the blood loss associated with the separation of placenta is significantly greater that in term labor.

Analysis of Variance↗
PubMed1995

Educating the diabetes care professionals in eastern Europe: a Bulgarian experience.

The first educational course for 30 medical doctors and 16 nurses, engaged in outpatient diabetes care in Bulgaria, was carried out with the aim of assessing the existing level of knowledge of diabetes, to implement a training programme matching the assessed needs, and to evaluate the efficiency of the education delivered. The initial level of knowledge was assessed by an anonymous pre-test questionnaire on general issues of diabetes care. After 5 days of training, a post-test questionnaire was administered which included more specific questions on matters that had been taught during the course. The results of the pre-test showed that, on average, 60.3 +/- 20.6 (SD) % of the doctors and 50.5 +/- 25.0% of the nurses gave correct answers. The results of the post-test were significantly improved (73.5 +/- 20.6% for the doctor and 70.8 +/- 23.5% for the nurses), although the post-test questionnaire had been expertly evaluated as more complex and specific. The analysis of the results allowed us to draw general conclusions regarding the educational needs, the optimal structure, and implementation of such training courses in the specific conditions of Bulgaria. Some of the results and conclusions might be useful for other countries from Central and Eastern Europe in their efforts to promote successful diabetes education programmes.

Adult↗
PubMed1995

[The place of vacuum extraction in modern obstetrics].

A clinical trial was carried out on the use of vacuum extraction for delivery of 45 women. The aim of the study is to revive again this method for it was rarely used during the last years. The authors remind of the indications and necessary condition for the use of vacuum extraction and report about complications and the course of the placental period. Parallel to this, the 45 babies born with vacuum, are followed up according birth weight, gestational age, clinical status and laboratory data by birth, resuscitation after delivery and birth trauma. By summing up the results the authors divide women (and babies) in 3 groups: deliveries with vacuum extraction (VE), VE+ forceps, Vstimmulation and forceps, Conclusions are made that VE is a useful method nowadays if classical conditions and indications are followed. The babies born by VE are in good status without serious traumas. Vstimmulation + forceps is rejected as more harmful method.

Adult↗
PubMed1992

Ionized calcium in patients with chronic renal failure.

Parameters of various renal disorders were studied in 31 patients (17 men and 14 women) who all were in the stage of chronic renal failure (CRF). These parameters included total serum creatinine, ionized calcium, serum creatinine, creatinine clearance and acid-base balance. The results were compared with a control group of 30 healthy subjects. In the patients with first stage CRF, the total serum calcium did not significantly decrease (mean = 2.19 +/- 0.12 mmol/l) and ionized calcium was within reference value limits (mean = 1.28 +/- 0.02 mmol/l). The percentage of ionized calcium in total serum calcium was higher for these patients (mean = 58.43%) than for the control group (mean = 52.25%). For patients with first and second stage CRF, the total serum was significantly lower (mean = 1.92 +/- 0.03 mmol/l) than for the healthy controls (p < 0.001) as well as for patients with first stage CRF (p < 0.05). The ionized calcium in these patients was not significantly lower (mean = 1.14 +/- 0.01 mmol/l); however, its percentage was higher than that of serum calcium (mean = 59.38%). There was a slight negative correlation between the levels of ionized calcium and serum creatinine in patients with first stage CRF (r = -0.30) and a significant correlation in patients with second and third stage CRF.

Adult↗
PubMed1990

[A clinical trial of the preparation palin in women with refractory colpitis].

The authors carried out clinical trial of the preparation Palin (pipemidinic acid) on 43 women with persistent colpitis after preliminary testing. There was negative microbiological finding in 67% of women. The results of the authors differed from those of other authors, since Palin was used mainly in women with chronic colpitis resistant to routine treatment. Minimal side effects were found. Usage of Palin is recommended in women with colpitis, caused by: E. coli, Enterococcus, Klebsiella and mixed aerobic flora.

Bacteria↗
PubMed1990

[The pregnancy outcome and changes in the blood volume in relation to the time of the appearance of late toxicosis symptoms].

The author studied plasma volume and mass plasma proteins on pregnant women with late toxicosis, occurring before and after 37 weeks' gestation, as well as respective groups of healthy pregnant women--113 in all. In comparison with control groups of healthy pregnant women, the women with late toxicosis, occurred before 37 weeks' gestation, had a considerable reduction in plasma volume and in the mass plasma proteins and an increase in hematocrit, but women with symptoms of late toxicosis, occurred after 37 weeks' gestation, had an increase in plasma volume and mass plasma proteins and a reduction in the hematocrit. Delivery occurred on the average during 38.6 weeks' gestation and the newborns had weight lower with 10.8% than the respective children in the country at the same period in the group of women with toxicosis, occurred early. In women with symptoms of late toxicosis the delivery occurred during 40.4 weeks' gestation larger children than normal were born and the pregnant women gained weight considerably more. The results from the study give foundation to assume that there is no late toxicosis when the symptoms of late toxicosis occur after 37 weeks' gestation, because of which the time of occurrence of the disease should be taken into consideration in establishing the diagnosis of late toxicosis of pregnancy.

Birth Weight↗
PubMed1987

[Experimental Salmonella dublin infection in calves].

Calves, aged 20 days, were experimentally infected with Salmonella dublin. The animals of one-group were treated at the rate of 6.10(8), and those of another--at 2.10(10) up to 4.10(10) live bacterial cells. The calves of the first group showed no clear clinical symptoms of a disease; neither did they manifest regular shedding of bacterial cells. The calves of the second group presented a typical clinical picture, with more regular shedding of bacteria through nasal discharges and the feces. After killing the animals Salmonella dublin organisms were found in all parenchymal organs and in the lymph nodes. Morphologically, the prevalence was established of inflammatory necrobiotic processes in the liver, with activation and proliferation of the sinus endothelium of the lymph nodes, and catarrhal inflammation of varying manifestation in the small intestine.

Animals↗