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A Dimitrov

Publications and source records attributed to A Dimitrov.

At least 37 records · Page 2Linked to original sources

Evidence for an exotic S= -2, Q= -2 baryon resonance in proton-proton collisions at the CERN SPS.

Results of resonance searches in the Xi(-)pi(-), Xi(-)pi(+), Xi;(+)pi(-), and Xi;(+)pi(+) invariant mass spectra in proton-proton collisions at sqrt[s]=17.2 GeV are presented. Evidence is shown for the existence of a narrow Xi(-)pi(-) baryon resonance with mass of 1.862+/-0.002 GeV/c(2) and width below the detector resolution of about 0.018 GeV/c(2). The significance is estimated to be above 4.2sigma. This state is a candidate for the hypothetical exotic Xi(--)(3/2) baryon with S=-2, I=3 / 2, and a quark content of (dsdsū). At the same mass, a peak is observed in the Xi(-)pi(+) spectrum which is a candidate for the Xi(0)(3/2) member of this isospin quartet with a quark content of (dsus[-]d). The corresponding antibaryon spectra also show enhancements at the same invariant mass.

Journal Article↗

[Emergency contraception with levonorgestrel for teenagers--efficacy, tolerability, and level of information awareness].

OBJECTIVE: Assessment of efficacy and side effects of emergency contraception for teenagers with levonorgestrel (LNG) and the level of users' informedness about possibilities and practical application. METHODS: The subjects are healthy girls (n = 49) with regular menstrual cycles at the age between 15 and 19, having had one unprotected or faultily protected sexual intercourse. All of them have administered 0.75 mg LNG within the 72nd hour, repeated after 12 hours. The data have been processed by variational analysis. RESULTS: One pregnancy was registered of a girl with firstintake at the 67th hour - pregnancy rate - 2,0%. The most frequent side effect was nausea - 26,5%, folowed by breast tenderness - 22,4% and fatigue - 20,4%. An up to 7th day delay in menstrual cycle is non significantly more frequent - 14,3%, followed by a delay of more than 7 days breakthrough bleeding - 8,2%. No significant changes were established in the lenght of the menstrual cycle. Emergency contraception is sought for after unprotected sexual intercourse in 69,4%, and condom failure problems in 30,6%. Only 18,4% have sufficient information about the possibilities and practical use of emergency contraception. CONCLUSION: LNG provides effective, highly tolerable contraception with a small number of side effects. Need is felt for serious popularization of the application of emergency contraception with teenagers.

Adolescent↗

[Immunostimulation as a part of urologic infection therapy in pregnancy].

Twenty-six pregnant women (group I) with uroinfection were treated with Urostim and antibiotic. The effect of treatment was compared to that of 20 pregnant women (group II) treated with antibiotic only. In group I recurrence of infections was found out in 15.3%, while in group II in 55%. We would like to offer it as part of the treatment of uroinfections with pregnant women, because it will reduce the usage of antibiotics and the recurrence of the uroinfections in postpartum period.

Anti-Bacterial Agents↗

[Study of women preference regarding mode of delivery].

The aim of this inquiry study is to assess the women's preference for abdominal or vaginal delivery in 113 women, divided in tree subgroups: 38 nonpregnant, 38 pregnant with one more births and 37 puerperas. All women are with high education and 49.6% of them had past at least one university exam of obstetrics and gynecology. 42.1% of nonporous women and 40.9% from parous would like to deliver CS. With the time from vaginal delivery the preference for vaginal deliver again decreases from 84.2% to 60.9% of cases. All women delivered by CS prefer CS again. Complications of vaginal delivery are factor for increasing CS rate. The pain relief of vaginal delivery does not increase the preference for vaginal deliver again. In 40% of women there is steady desire for vaginal delivery despite previous complications or full medical information for the concrete conditions. 88.5% of inquired women agree with "CS on request".

Adult↗

[Shoulder dystocia--risk factors and fetal outcome].

The purpose of this retrospective study is to evaluate the perinatal outcome in cases with birth injuries, suggesting shoulder dystocia. This survey involves 92 cases of live newborns (gestational age between 37 and 42 weeks) with shoulder injuries. Another control group of 120 cases of live mature newborns without any shoulder injuries is studied for comparison. There are no significant differentialities between those two groups, regarding age, parity, weight and height of the parturients. Shoulder dystocia is most frequently found in newborns of 3500-4000 g birthweight. Antepartum, risk factors for shoulder dystocia are: diabetes, obesity of the mother and chronological postterm pregnancy. Intrapartum, the evaluated risk factors prove to be unreliable because the same were found in as many as one half of the non-traumatic vaginal deliveries. In 27% of the cases, shoulder dystocia occurs most probably after the passage of the shoulder through the pelvic inlet. The most frequent type of shoulder injury is fracture of the clavicle (90.2%), followed by paresis of the brachial plexus (7.6%). Severe shoulder dystocia both from obstetrical and neonatological point of view is found in 2-3% of the cases.

Adult↗

[Significance of fetal factors in prognosis of outcome after labor induction].

Aim of the present mixed prospective and retrospective study is to determine the prognostic significance of fetal factors for the continuity and the final outlet of induction of labor. Factors like fetal weight, placental maturity according Grannum, status of the amniotic membranes and amniotic fluid index by Phelan were examined. Based on the given results the authors conclude that there is no dependence between the expected overweight of the fetus and the continuity and the final outcome of induction of labor. The immature placenta and the increased amniotic fluid index are related with prolonged inductions of labor but the terminal outcome is not influenced by them. Premature rupture of the amniotic membranes cause prolonged inductions and the preserved membranes with an increased frequency of unsuccessful inductions.

Amniotic Fluid↗

[Causes of urinary tract infection in pregnant women].

Data of etiology characteristics of uroinfections with pregnant women are presented treated at University Hospital of Obstetrics and Gynecology "Maichin dom" in three periods. Gram negative species of microorganisms (E. coli, proteus, Klebsiella) are the agens of uroinfections in 95.4% of cases in the period 1988/89. After 10-year period gram (-) are the uroinfection in 66.1% of the cases. The growing etiologycal importance of Gram positive species of microorganisms (S. aureus, Enterococcus, GBS) is 33,9% in the period 1997/98 and it is preserved in june 2001/may 2003 too. In cases of long lasting hospitalization or after repeated treatment with antibiotics the probability grows that the agents of uroinfections be polyresistant strains. In the period june 2001/may 2003 in 7% of the cases polyresistant E. coli are isolated, in 2.6% MRSaureus, in 7.6% Ampicillin - R Enterococcus spp. That suggest exact identification of the agen and therapy according to sensitivity to antibiotics.

Anti-Bacterial Agents↗

[Intrapartum oxygen saturation in fetus with symptoms of distress shown during fetal cardiotocograph monitoring].

The aim of the study is to establish the mean values of SpO2, during labour with symptoms of fetal distress and to find out when fetal hypoxia is expected to develop as well as unsatisfactory clinical status of the newborn. The study includes 62 women on labour at term with pathological decelerations from the fetal heart rate (FHR). SpO2 is monitored by means of fetal pulse oxymeter Nellcor N 400. Simultaneously FHR is monitored by means of cardiotocography. Fetal well-being is verified by pH u blood gas analysis from fetal scalp while the newborn well-being is proven by pH from umbilical artery and Apgar score at minute 1 and 5 after birth. The mean continuity of SpO2 recording during the first period of labour is 107.84 +/- 25.77 min., with mean 86.74 +/- 7.06% reliability of the recordings; for the second period--26 +/- 8.98 min. with reliability of the recordings 77.07 +/- 9.96%. During the first period of labour the mean value of SpO2 is 43.00 +/- 6.75%. With dilation of 4-5cm SpO2 is 46.25 +/- 5.92%, with 6-7CM SpO2 is 44.43 +/- 6.39% and with 8-9cm dilation SpO2 is 42.69 +/- 6.80%. During second period of labour the mean value of SpO2 is 39.14 +/- 8.41%. There is a statistically significant fall of SpO2 during the second period compared to the first period of labour (p<0.05). A correlation exists between the values of SpO2 and the well-being of the newborn and a fall of SpO2 equal or less than 30% is a sign of developing abnormal condition of the newborn.

Adult↗

[Endometriosis during postmenopausal period--probable causes for its origin and development].

A very rare--casuistic--case of endometriosis is presented, which appeared ten years after surgical menopause (hysterectomy and ovariectomy) without concomitant use of hormone replacement therapy or phytoestrogens. The possibilities of endogenous production and exogenous supply of estrogens in the female organism are discussed as well as the possible causes of proliferation of endometrial lesions during postmenopausal period. When menopause is induced by surgery (a stress for the organism) without exogenous supply of estrogens (HRT, phytoestrogens, xenoestrogens) the production of suprarenal hormones, including androgens, increases. The peripheral conversion of androgens into estrogens in fat tissue is increased and implanted during hysterectomy endometrial lesions in vagina walls are stimulated.

Aged↗

[Antenatal ultrasonographic and Doppler color diagnosis of placenta previa/accreta focalis].

A case of placenta previa/accreta focalis was diagnosed at 29 weeks gestation in a 40 year-old patient using color Doppler ultrasound. A picture of intense blood flow within the placental sonolucent spaces, with vessels crossing from the placenta into the uterine wall was evident. A Cesarean section was performed. The macroscopic examination of the uterus during the operation revealed a focal invasion of the placental villi throughout the myometrium.

Adult↗

[Study of the effect of Propess for ripening of the unfavorable cervix for the induction of labor due to medical indications].

The purpose of this study is to proceed and estimate the effect of Propess for cervical ripening for induction of labor due to medical indications. Seventy pregnant women are included divided in two groups-36 of them with vaginally applicated Propess and the other 34 are at the control group. Changes in the cervix, induction of uterine activity, labor, status of the fetus and the side effects are proceeded. In the group with vaginally applicated Propess 9 of the patients gave birth till the twelfth hour from the application of the pessar. The Bishop score increased over 6 points in 7 of them and increased by 3 points in 11 of the cases within 12 hours. In the control group no delivery is registered till the twelfth hour, in two of the cases there is an increase of the Bishop score over 6 points and only in 5 of the cases is estimated an increase of the Bishop score with 3 points. There is one case of uterine hyperstimulation. There was no other side effects.

Administration, Intravaginal↗

[Submucosal isthmicocervical myoma--problems of diagnosis, labor and puerperium].

A case of submucosal isthmicocervical myoma, 85 mm in diameter, diagnosed for first time during CS. The neonate is with atrophy of left m. sternocleidomastoideus and facial asymmetry due to impression in the left temporoparietal region, without neurological impairment. Multiple ultrasound examinations were done but the fibroids vas not diagnosed. During one examination we presume that the fibroid was mistaken for the head because the BPD was in great discrepancy with other ultrasound parameters of the fetus. During the operation OICC was not found that is why the dilatation was made through the vagina. A myomectomy was not made during the operation. Because of the pressure and the deformation of the cervical canal from the myoma a drain was inserted through the canal to facilitate the evacuation of the lochia. The post operative period passed without any complications, the drainage was taken off on the 7th post operative day and the patient was discharged on the 8th day.

Adult↗

[Rate of cesarean section and perinatal infant mortality at "Maichin dom"].

The aim of this retrospective study is to find the CS rate, which to maintain the perinatal mortality at a lowest possible level in groups of patients with normal and high risk pregnancies. There were 123598 births for a period from 1976 to 2000 years. The CS rate has increased from 4.8% to 24.5% and the PNM has decreased from 27.7@1000 to 11.4@1000. The statistical analysis shows that the for this period the CS rate is one of the factors to decrease the PNM (r = -0.776, p < 0.05). In the group of pregnancies with normal risk the PMN is between 8 and 11@1000 at the CS rate of 15-16% while in the group with high-risk pregnancies the same PNM is achieved with 24-26% CS rate. The antenatal mortality is not influenced by the CS rate and is almost unchanged for 24 years (r = -0.339, p > 0.05).

Bulgaria↗

[Analysis of indications for a repeat Caesarean section].

The aim of the study is to establish the indications for a Resectio Caesarean (RS) and to compare them with those of the first Caesarean section (CS). The Study is retrospective and covers the period from 1.1.2000 to 31.XII.2000. For this period were accomplished 3646 deliveries, 894 (24.52%) of them with S. C. The RS were 182 (20.04%) of all CS. The number and the rate of each indication is calculate on the base of the sum of the first and the second indication from all CS. The first two indications reflect well the real reason for each CS. The results show that the average age of women with RS is grater 2 years and 7 months than those with first CS. The RS are elective in 80.7% of cases and is done at 38.4 +/- 1.4 w.g. The average weight of the newborns from RS is non significantly less with 31 g than this from first CS. The indication "status post CS" is not well defined as it is used in 98.3% of RS. The indication is accepted mostly as a relative one because is added in cases with enough reasonable other obstetric indications. The analysis of the indications of RS shows That 60% of them are justifiable 40% are undertaken on the bases of unconvincing complex indication, but which don't differ from those at first CS.

Adult↗

[Problems and outcome in extremely low birth weight newborns, depending on the mode of delivery].

THE AIM: Of this study is to determine the impact of the mode of delivery on survival, morbidity and prognosis of ELBW and extremely low gestational age (ELGA) newborns. METHODS: The retrospective review includes ELBW and ELGA infants born at the State maternity hospital "Maichin dom" Sofia from 1997 to 1999. These are 95 newborns divided into two groups: 31 born by Cesarean section (C. s.), and 64--per vias naturals (p. v. n.) with subgroups: 42--vertex, 22--breech delivery. Resuscitation is similar in all groups, according the routine practice. They are compared by the following indexes: rate of survival, Apgar scores at the 1-st and at the 5-th min, pH from the umbilical artery (u. a.), rate of the intraventricular hemorrhages (IVH) and periventricular leukomalacia (PVL), and early nevrodevelopmental outcome. RESULTS: The birth weight of all babies includes ranges from 500 to 999 g and the gestational age (g. a.) is > 24 weeks of gestation. There is no statistically significant difference (p < 0.05) according birth weight, pathology and treatment of the mother, between the two groups. In the C. s. group 17 babies survived (55%) while in p. v. n. 30 survived (47%), the worst was survival between the babies, delivered in breech presentation--7 (32%), p < 0.05. There is no significant difference between pH and BE from u. a., but Apgar scores are worse in the breech group, p < 0.05. The incidence of all grades IVH and PVL is almost the same, but there is a significant difference in the incidence of severe, grade 3 and 4 IVH and PVL (19% in C. s. group versus 48% p. v. n. group). The survivors with severe IVH are 57% among the breech delivered (p < 0.05) compared with respectively 33% and 26% among c. s. and vertex delivered groups. A CONCLUSION: Is made that C. s. provides better chances for a safe survival in ELBW and ELGA newborns and better prognosis for neurodevelopmental outcome. With the worst prognosis are the breech delivered ELBW babies.

Apgar Score↗

[Acute renal insufficiency during pregnancy with acute pancreatitis].

According to current data the incidence of acute pancreatitis is from 1:1000 to 1:5000. Symptoms vary a lot, one of rare but most severe complications being acute renal failure. The case is a 24-year-old pregnant patients--30-th gestational week with symptoms of acute pancreatitis based most probably on hereditary hypertriglyceridemia and hypercholesterolemia. Parallel to acute inflammation of pancrease a hypercoagulation syndrome developed. It is possible that acute renal failure was caused by active thrombus formation. Because of danger for the life of mother and baby, an urgency preterm Cesarean Section was performed. Resussitation post-surgery care and drug therapy (lowmolecular anticoagulants, antibiotics, spasmolytics and analgetics, protease--inhibitors, inhibitors of protome pump, regulators and inhibitors of pancreas secretion normalize renal and pancreatic function if based on special dietary regimr. Coagulation status also normalizes.

Acute Disease↗