Search PubMed⌕ Search

Biomedical subjects

A Dimitrov

Publications and source records attributed to A Dimitrov.

At least 19 recordsLinked to original sources
PubMed2006

[Assessment of Bishop's pelvic score in induction of labor prognosis].

Aim of the present mixed prospective and retrospective study is to determine the prognostic significance of the 5 parameters of the pelvic score of Bishop for the continuity and the final outlet of induction of labor. Based on the given results the authors conclude that the dilatation of the cervix is a good prognostic factor for the nulliparous and bad prognostic factor for multiparous. The effacement of the cervix is significant for the outlet of the induction regardless of parity. The level of the presenting part is a valuable criterion for the nulliparous when the pelvic is well assessed but for the multiparous it has no prognostic value. The firmness of the cervix has a bad prognostic value regardless of parity. The position of the is a good prognostic factor for the outlet of the induction but has no value prognosis of the continuity of the induction.

Cervix Uteri↗
PubMed2006

[Phlebothrombosis and thrombophlebitis during the second half of pregnancy and puerperium].

Fhlebothrombosis and thrombophlebitis of the cerebral veins and sinuses develop relatively rare, but they affect young people and have poor prognosis. Pregnancy and puerperium are et risk due to hormonal and homeostatic changes in the organism. This report exhibits the most frequent etiologic factor, early symptoms, clinical manifestation, diagnostic value of the different methods, treatment principals and the factors that determine the outcome of thrombofphlebitis and phlebothrombosis during pregnancy and puerperium. In the acute phase a treatment with direct anticoagulants (intravenous heparin or low molecular mass heparins) and symptomatic treatment with anticonvulsants and drugs against oedema. After the acute phase the treatment continues with oral indirect anticoagulant as long as the severity of the disease requires.

Female↗
PubMed2006

[Magnetic resonance imaging--diagnosis and differential diagnosis of tumor formations (cyst) in the abdomen cavity during pregnancy].

The existence of tumor formations with unidentified origin in the abdomen cavity of the pregnant can cause serious problems during the operative intervention. It is critical to find the organ origin of the existing formation and it's relations with the neighboring organs. In the following article we present some of the capabilities of the magnetic resonance tomography as a complementally to the existing in the clinical practice classical and special methods for diagnosis and differential diagnosis of tumor formations in the abdomen cavity during pregnancy. MRI locates precisely the organ origin, the type and the size of the cyst formation, furthermore it helps to determine in detail the access point, the type and size of the operative intervention. The technique is harmless concerning the pregnancy and the development of a normal, healthy fetus.

Abdominal Cavity↗
PubMed2006

[Pregnancy after treatment of primary sterility with zoladex in patient with essential thrombocytopenia].

We have a patient with essential /idiopathic/ thrombocitopeny and primary sterility, who becomes pregnant after medical and operative treatment. With the beginning of the menarche her menstrual cycle goes irregular with menstrual bleeding duration from 8 to 20 days, cystic ovaries, non-ovulation cycles, trombocytopeny and anemia. A laparotomy was performed twice, because of the existence of hemoperitoneum, caused by a rupture of the corpus luteum. After achieving a amenorrhoea with Zoladex treatment, a splenectomia was performed. As a result we observe a physiological recovery of the menstrual cycle, the ovulation cycle and the pregnancy. The patient's hematology and hemostaseology statuses went back to normal.

Amenorrhea↗
PubMed2006

[The efficacy of the misoprostol in cases of abnormal and pathologic hypotonic hemorrhage in the early puerperium].

UNLABELLED: The aim of this study is to determine the efficacy of the Misoprostol (Cytotec) in cases of abnormal and pathologic hypotonic hemorrhage in the early puerperium as a result of hypotonia of the uterus. MATERIAL AND METHODS: A group of 50 women with vaginal or abdominal labor developing hypotonic abnormal/pathologic bleeding after the placental delivery were given Misoprostol (Cytotec 200-400 microgr per rectum and/or per oral every 15 min). We compared this group with a control group without having postpartum bleeding. RESULTS: The application of Misoprostol resulted in uterine contraction and discontinuing the abnormal bleedings in both vaginal and Caesarian deliveries. The main blood lost in the next two hours period after vaginal labor didn't differ with the blood lost of the normal labors (66 ml vs. 75 ml). In the Caesarian deliveries the blood lost after application of the Misoprostol also didn't differ with the blood lost after normal caesarian section (78 ml vs. 80 ml). CONCLUSIONS: Misoprostol decreases the hypotonic uterine bleedings in the placental and early puerperal period. The significance of the Misoprostol in the group of therapeutic events is determined by its fast therapeutic effect, its convenient application and its good tolerance.

Administration, Oral↗
PubMed2006

[Vaginal candida infection in the third trimester of pregnancy].

The aim of this study is the determination of the frequency of vaginal Candida colonization in pregnant women in the third trimester, the status of the vaginal ecosystem, the grade and the subspecies of the candidal colonization, clinical manifestations and the therapeutic effect of the local antimycotic treatment. In this study it has been followed 172 pregnant women with a normal pregnancy at the end of the third trimester. It has been estimated that about 28.4% of all women get a vaginal yeast colonization - Candida spp. In 89.7% (44 women) of the cases, the colonization was caused by an overgrowth of the yeast Candida albicans. The remaining cases are caused by other subspecies of Candida - 5 cases (10.3%) - C. tropicalis /2/, C. parapsilosis /2/, C. glabrata/1/. The women in the first group were with symptoms of active candidosis (25.6%) and 88.3% of the cases were confirmed by microscopy, and 90.6% after a bacterial growth in a culture. In 7.7% of the cases was specified a mild to moderate colonization without a clinical signs of infection (II group). The local treatment with antimycotic vaginal globules and crème for 5 to 7 days alleviates the clinical symptoms. It was not observed a case of maternal - fetal transmission of this infection not a clinical manifestation in the early postpartal period.

Candida↗
PubMed2005

Omega- and Omega+ production in central Pb + Pb collisions at 40 and 158A GeV.

Results are presented on Omega production in central Pb+Pb collisions at 40 and 158A GeV beam energy. For the first time in heavy ion reactions, rapidity distributions and total yields were measured for the sum Omega(-) + Omega(+) at 40A GeV and for Omega(-) and Omega(+) separately at 158A GeV. The yields are strongly underpredicted by the string-hadronic UrQMD model but agree better with predictions from hadron gas models.

Journal Article↗
PubMed2005

System-size dependence of strangeness production in nucleus-nucleus collisions at squareroot[sNN]=17.3 GeV.

Emission of pi+/-, K+/-, phi, and Lambda was measured in near-central C+C and Si+Si collisions at 158 AGeV beam energy. Together with earlier data for p+p, S+S, and Pb+Pb, the system-size dependence of relative strangeness production in nucleus-nucleus collisions is obtained. Its fast rise and the saturation observed at about 60 participating nucleons can be understood as the onset of the formation of coherent systems of increasing size.

Journal Article↗
PubMed2005

[Reference values range of the fetal oxygen saturation and its dispersal during labor without cardiotocographic evidence for fetal distress].

UNLABELLED: The objective of this study is to establish the reference values range of the fetal oxygen saturation during the first and the second period of labor and their dispersal according to the extent of cervical dillatation in cases with normal FHR--absence of fetal hypoxia and asphyxia of the newborn. MATERIAL AND METHODS: This is a prospective study which involves 94 women with normal FHR. All of the newborns are with umbilical artery pH values greater than 7.15 and 5 min Apgar score greater than 7; there was no necessity for any reanimation procedures, assisted ventilation or intensive care treatment. The fetal oxygen saturation (SpO2) is monitored by fetal pulseoxymeter Nellcor N 400, fetal sensors FS - 14. Cardiotocographic monitoring is carried out simultaneously. Blood is obtained from the fetal scalp during labor for blood gas and pH analysis, and umbilical artery pH as well as the Apgar score of the newborn are determined. RESULTS: The average monitoring time during the first period of labor is 107.19+/-29.49 min. with reliability of the recordings 86.54+/-6.10%. The average monitoring time for the second period of labor is 36.72+/-8.31 min. with reliability of the recordings 75.42 +/-9.61%. The mean SpO2 values are 48.71+/-5.52% during the first period and 47.30+/-4.62% during the second period of labor. The reference SpO2 values ranging between the 25-th and 75-th percentile in fetuses with normal FHR are 46-52 % for the first and 44-50 % for the second period. The results for fetal SpO2 during the different stages of cervical dillatation are as follows: for 4-5 cm - 49.49+/-5.12%, for 6-7 cm - 48.76+/-5.42%, for 8-9 cm - 48.39+/-5.49%. CONCLUSIONS: The fetal SpO2 dispersal during cervical dillatation of 4-5, 6-7 and 8-9cm accordingly demonstrates a nonsignificant decrease of SpO2 for the different groups (p>0.05). The fetal SpO2 dispersal between the first and the second period of labor also demonstrates decrease of SpO2 values and shows a minor statistically significant difference (p < 0.05 - Repeated measures ANOVA), which is considered to be within the normal range and does not reflect on the newborn's well-being.

Apgar Score↗
PubMed2005

[Localization of leiomyoma with respect to the placenta--factor for complications during pregnancy?].

We are presenting two cases of pregnant women with leiomyoma of the uterus, diagnosed antepartum. In both cases the patients were admitted on an emergency basis due to premature uterine contractions. In both cases preterm hemorrhage and fetal malpresentations were observed. The complications of pregnancy in both of the cases were primarily based on the location of the leiomyoma with respect to the placenta--intramural or submucosal disposition of the leiomyoma, retroplacentarily situated.

Adult↗
PubMed2005

[Prognostic significance of Bishop's pelvic score for the continuity and the final outlet of induction of labor].

Aim of the present mixed prospective and retrospective study is to determine the prognostic significance of the pelvic score of Bishop for the continuity and the final outlet of induction of labor and to determine the optimal score in the beginning of the induction related with a successful outlet. Based on the given results the authors conclude that the pelvic score of Bishop has a good prognostic value for the continuity and the final outlet of induction of labor with a various values of the separate parameters. Pelvic score > or = 5 is related with a shorter and more successful inductions of labor.

Delivery, Obstetric↗
PubMed2005

[Treatment of life-threatening bleeding in obstetrics and gynaecology --NovoSeven (recombinant factor VIIa)].

The study offers the results from the application of recombinant factor VIIa (NovoSeven) in 19 patients with obstetric or gynaecological problems showing severe haemorrhage of non-surgical origin, which could not be controlled by standard therapy (surgery and resuscitation). Haematological and haemostaseological values as well as final outcome are being monitored. The role of the drug and its special indications in complex urgent treatment of life-threatening bleeding are being discussed. Conclusions. The use of NovoSeven (recombinant factor Vlla) on time and when indicated guarantees rapid and effective haemostasis. Thus laparotomy or relaparotomy can be avoided. If no effect is observed after the application of NovoSeven indicates bleeding from a major blood vessel, demanding laparotomy and surgery. The use of the drug leads to reducing the incidence of blood derivatives transfusions and (being a recombinant product)--no risk of transmissive infections.

Factor VIIa↗
PubMed2005

[Contraception in women with diabetes mellitus].

Contraception in women suffering of diabetes mellitus is an important question mainly due to it has been proven that pregnancy outcome both for the fetus and for the mother depends on glycemic control before conception right to delivery. That's made planning of future pregnancy mandatory for patients with diabetes mellitus. Patients are advised for contraception until optimization of metabolic control has been achieved or until complete and contemporary treatment of the diabetes complications has been fulfilled. Incorrect contraceptive method could extend metabolic disorders and to reinforce vascular complications of the diabetes. Choice of contraception depends on the aim: short lasting contraception aiming on future pregnancy planning or long lasting contraception aiming on family planning. In women with diabetes mellitus it is extremely important to take into consideration such factors as type of the diabetes, its lasting, degree of metabolic compensation, presence of diabetic complications, body-mass index of the patient, presence of risk factors for cardiovascular diseases and future pregnancy planning. In cases when pregnancy is planning it has been preferred local contraception, such as condoms, diaphragms. In cases of nullipara or in women with plenty of partners, condoms are method of choice. In women who gave birth intrauterine device is such a method. In women with diabetes mellitus type I (insulin dependent diabetes mellitus) it is possible to use hormonal contraception depending on patient's request or on medical indications only in cases when diabetes has less than 15 years duration and microangiopathic complications and other vascular risk factors lack. Combined hormonal contraceptive preparations have to contain less than 30 microg ethinylestradiol and gestagen of "third" or "fourth" generation. This contraception has to be prescribed together with insulin dosage correction and demands on strict metabolic control of the diabetes and body weight. When the combined preparations are contraindicated it could be suggested progestagenic oral hormonal contraception if gynecologic contraindications lack and if this not leads to menstrual disturbances. In women with diabetes mellitus type II (non insulin dependent diabetes mellitus) combined hormonal contraceptives has not to be used, because they could provoke clinical manifestation and deteriorate progress of the diabetes mellitus.

Contraception↗
PubMed2005

[Cesarean section for fetal distress--is the decision interval for delivery significant?].

UNLABELLED: The recommended Interval between the decision to perform emergency cesarean section and the delivery itself is 30 minutes. There is not enough clinical evidence in maintenance of this opinion. AIM: to study the interval from the decision of the cesarean section for fetal distress to delivery itself, as well as to analyze fetal and mother's outcome. METHODS: Prospective 13-month-study for the period 2003-2004 in Delivery room "Majchin Dom" included observation of 125 women. Cesarean section is classified in 3 Categories--1st--deemed highly hazardous for mother or/and fetus (crush); 2nd--not directly hazardous for mother or/and fetus (emergency); and 3dt--not direct mother or/and fetal distress, but the delivery is necessary in a short period of time (urgency). The Interval and the Categories are comparable with the presence or absence of fetal distress (Apgar < 7, pH < 7.20). RESULTS AND DISCUSSION: Positive results are found in the 1st category when the C-section is performed in 30 minutes. There are significant differences between the three Categories--the percentage of fetal distress is growing up comparable to prolongation of the time interval. Prolongation of the time interval for more than 60 minutes lead to poor fetal outcome.

Apgar Score↗
PubMed2005

[Optimization of prenatal screening for group B streptococcus].

The prophylaxis of endogen B streptococcal infections (GBS are part of the normal flora of the gastrointestinal and genital tract) in the presence of predisposed conditions for development of experience for every delivery (tissues' damage, time of delivery, loss of blood, obstetrics manipulations) has been a complicated objective. In the University Hospital of Obstet. Gynecol. "Maichin dom" have been delivered annually on the average 0,6-0,9/1000 born alive with GBS sepsis. The medium Granada shortens the duration for detection of GBS by 24 hours. On entrance of a pregnant woman the direct inoculations of cervico-vaginal secretions and the fast positive reactions of GBS can assist the therapeutical behavior of the mother as well as the newborn.

Female↗
PubMed2004

Lambda and lambda production in central Pb-Pb collisions at 40, 80, and 158A GeV.

Production of Lambda and Antilambda hyperons was measured in central Pb-Pb collisions at 40, 80, and 158A GeV beam energy on a fixed target. Transverse mass spectra and rapidity distributions are given for all three energies. The Lambda/pi ratio at midrapidity and in full phase space shows a pronounced maximum between the highest BNL Alternating Gradient Synchrotron and 40A GeV CERN Super Proton Synchrotron energies, whereas the Lambda/pi ratio exhibits a monotonic increase.

Journal Article↗