Biomedical subjects
Publications and source records attributed to A D Steinfeld.
The rise in the level of environmental radiation resulting from man's activities has been relatively small in relation to naturally occurring background [corrected] radiation. (One exception to this is microwave radiations.) There are no quantitative data on the effects of low levels of radiation on man, and the possible health consequences remain unclear. The risks of hazardous amounts from x-rays can be minimized by careful use.
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Gray scale ultrasound B-mode scanning provides a rapid and safe method for evaluating the origin of a pulsatile midline abdominal mass. In those patients who do not have an aortic aneurysm, ultrasound will frequently provide another explanation. Tortuous aortas, pancreatic pseudocysts, metastatic cancers, lymphomas, and low-lying livers may all present as pulsatile masses clinically mimicking an aortic aneurysm. Visualization of the para-aortic soft tissues as well as the aorta allows these conditions to be distinguished by abdominal ultrasound.
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Many patients as children or adolescents received treatment for nonmalignant conditions with therapeutic-range doses of ionizing radiation. Great interest exists in this group of patients because of the possible long-term adverse effects of such irradiation. A thorough physical examination should be performed, and a careful history, listing any instances of radiation exposure, should be taken. Photographic documentation of skin and/or mucosal changes is beneficial.
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Postoperative radiation therapy was given for medullary carcinoma of the thyroid in 5 patients. Moderately high doses of radiation achieved local control. Four patients died of metastatic disease. The favorable response of this tumor to doxorubicin suggests that both postoperative irradiation and chemotherapy should be used in its treatment.
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Testicular infiltration developed in 6 of 56 boys with lymphoblastic leukemia. All exhibited platelet counts under 100,000, indicating poor prognosis. Patients were treated with vincristine, prednisone, and craniomemingeal prophylaxis (2,400 rads/12 fx) extending to the C2 level. Only 3 patients did not suffer recurrence of testicular disease during their multiple leukemic relapses. Alternate treatment courses are suggested.
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Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.