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Biomedical subjects

A Chaoui

Publications and source records attributed to A Chaoui.

At least 19 recordsLinked to original sources

[Bilateral breast cancer. Incidence and risk factors].

OBJECTIVE: To clarify, thanks to a retrospective study of 24 bilateral breast cancer cases, the frequency, the risk factors and the prognosis of bilateral breast cancers. PATIENTS AND METHOD: Between 1984 and 1999, out of 506 patients treated for unilateral non-metastatic breast cancer at Gynecologic and Obstetric ward, at Maternity Souissi of Rabat, 24 cases of bilateral breast cancers were diagnosed. Our results were compared to those of the literature. RESULTS: The frequency of bilateral breast cancers was 4.7% (24/506). In 87.5% of cases, these were metachronous cancers with a mean interval of 45 months (12-144 months). Patients under 40 at first cancer ran a fivefold superior risk than women more than 40 (P < 0.05). In cases of T3 or T4 tumors, the risk was 10-fold superior to that in smaller ones (P < 0.05). DISCUSSION AND CONCLUSION: Significantly more first metachronous tumors were invasive adenocarcinoma cancers. Histologic type of first and second tumor was the same in all cases. The prognosis depends at once on the first and second cancer staging and the treatment must be done according to the same rules as in the first cancer.

Adenocarcinoma↗

[Primary malignant melanoma of the cervix].

INTRODUCTION: Primary malignant melanoma of the cervix is an extremely rare histological variety of cervical tumor, with only 54 cases reported. OBSERVATION: A 70 year-old woman consulted for metrorrhagia and pelvic pain. Clinical examination revealed a tumefaction on the anterior labium of the cervix. The anatomo-pathological examination of the biopsy led to diagnosis of a malignant melanoma of the cervix. Despite enlarged Wertheim-type colpohysterectomy associated with pelvic lymphadenectomy, pulmonary metastases developed and the patient died six months later. COMMENT: This is a typical case of malignant melanoma of the cervix. All the authors underline the poor prognosis when visceral metastases occur early, as was the case in our patient.

Aged↗

[Angiosarcoma of the breast: a case report].

We report a breast's angiosarcoma case admitted at the maternity hospital Souissi of Rabat in 1997. We discussed epidemiologic, diagnostic and therapeutic aspects of this type of tumor insisting on the difficulties of diagnosis.

Adult↗

[Gestational trophoblastic diseases. Apropos of 105 cases].

The authors report a retrospective study of 105 observations of gestational trophoblastic diseases managed at the university clinic of obstetric gynecology I (Pr Chaoui). Of this study, one listed 72 cases of complete mole hydatiforme with 5 cases of sacrofetal pregnancy. The invasive mole is found in 4 cases and the choriocarcinoma in 24 cases. The general frequency of this pathology is of 1/770 pregnancies. The age of our patients varies from 15 to 52 years with an average age 27 years and the multiparity is found in 50% of the cases. 103 patients (95.5%) consulted for metrorrhagia associated pelvic pains in 31 cases (30%). The toxic syndrome was present in 20 patients (12%) with a preeclampsy in 6 cases (5.71%). The physical examination showed a very increased uterus of size in 92 cases (87.5%) associated adnexal mass in 37 cases (35.2%). The diagnosis was especially echographic in the totality of the cases associated or not with a proportioning of plasmatic beta HCG or prolans urinary. The treatment of the trophoblastic disease varies simple endo-uterine aspiration (85%) until the chemotherapy treatment (32.4%), the hysterectomy was indicated in a third of the cases. The evolution of the non complicated mole hydatiforme was good in 100% of the cases, it quasi totality of the invasive moles presented a complete remission. Among the 24 choriocarcinoma, we deplore 4 deaths in a table of pulmonary, hepatic and cerebral metastases. In order to improve the forecast of these diseases, the diagnosis must be early with an adequate treatment and a rigorous monitoring.

ABO Blood-Group System↗

[Breast tuberculosis].

Tuberculosis rarely affects the breast. The authors report the case of a 50 years-old woman with breast tuberculosis. The main purpose of this case report is to remind clinicians of the unusual presentations of extrapulmonary tuberculosis that can easily be forgotten. Mammary tuberculosis presents a number of diagnostic pitfalls. Diagnosis is based on identification of the tubercle bacillus in cultures or demonstration of typical histological lesions. Antibacillary drugs are the mainstay of therapy. Surgery is used only is cases that fail to respond to medical treatment and/or involve extensive tissue damage. Although rare, tuberculosis of the breast should be considered as a possible diagnosis, particularly in countries where tuberculosis is endemic.

Breast Diseases↗

[Renal transplantation and pregnancy. Report of a case].

The authors report a case, the first in Morocco, of a kidney transplanted woman pregnancy. The pregnancy occurred eleven months after the kidney transplantation. The renal function has not been modified. Treatment immunosuppressor has been maintained. The pregnancy evolution has been marked by a moderate hypertension arterial without child reverberation. To shortcoming this observation and to the lights of data of the literature, authors recalls factors that condition the stability of the renal function and the good progress of pregnancy and insist on the necessity of the scheduling of pregnancy and a multidisciplinary surveillance.

Adult↗

Incidence of adrenal masses in patients referred for renal artery stenosis screening MR.

RATIONALE AND OBJECTIVES: Prior work has shown the efficacy of magnetic resonance (MR) in renal artery stenosis evaluation. The increasing role of renal artery stenosis in the differential diagnostic evaluation of hypertension raises the question of whether MR should be used as a screening modality. This project evaluated the additional potential benefits of MR by determining the incidence of adrenal masses in this selected population. METHODS: A 2-year retrospective study analysis of patients who failed to respond to antihypertensive medical management and were referred for renal MR for hypertension amassed 77 subjects ranging in age from 18 to 88 years. A masked analysis for adrenal masses was performed on this data set. Magnetic resonance techniques included T2-weighted turbo spin-echo (repetition time [TR] 2000-4000 ms, echo time [TE] 80-100 ms, turbo factor 2-16), T1-weighted spin-echo (TR 200-500 ms, TE 10-30 ms), gradient-echo time-of-flight (TR 26 ms, TE 6.9 ms, 40 degrees flip angle, 2 excitations), and dynamic gadopentetate dimeglumine-enhanced MR angiography (three-dimensional gradient recalled echo, TR 10 ms, TE 3 ms, 40 degrees flip angle, 1 excitation). RESULTS: Thirty-three patients had renal artery disease, 44 had normal renal arteries, and 7 had adrenal masses. Forty-three percent of patients who underwent renal MR had disease of the renal arteries detected, and 9% of patients referred for MR had adrenal masses that would have been missed with scintigraphy and/or angiography, of which 57% were responsible for hypertension. CONCLUSIONS: The ability to evaluate renal artery and adrenal anatomy globally can be useful, as exemplified in the current series, and the adrenals should be examined carefully in any renal MR in a hypertensive patient.

Adolescent↗

[Congenital cystic adenomatoid malformation of the lung. Prenatal diagnosis in a case].

We report a case of congenital cystic adenomatoid lung malformation, type I in the Stocker classification, diagnosed at ultrasonography at 27 weeks gestation. The lesion stabilized as was the hydramnios. Vaginal delivery was uneventful. Early surgery with lobectomy led to a favorable outcome at 8 months follow-up. Congenital adenomatoid lung malformation is a rare finding. Prenatal ultrasound diagnosis has enabled early treatment and improved prognosis.

Adult↗

Standardized measurement of the future liver remnant prior to extended liver resection: methodology and clinical associations.

BACKGROUND: There is no agreement regarding the preoperative measurement of liver volumes and the minimal safe size of the liver remnant after extended hepatectomy. METHODS: In 20 patients with hepatobiliary malignancy and no underlying chronic liver disease, volumetric measurements of the liver remnant (segments 2 and 3 +/- 1) were obtained before extended right lobectomy (right trisegmentectomy). The ratios of future liver remnant to total liver volume were calculated by using a formula based on body surface area. In 12 patients, response to preoperative right trisectoral portal vein embolization was evaluated. In 15 patients who underwent the planned resection, preoperative volumes were correlated with biochemical and clinical outcome parameters. RESULTS: The future liver remnants increased after portal vein embolization (26% versus 36%, P < .01). Smaller size liver remnants were associated with an increase in postoperative liver function tests (P < .05) and longer lengths of hospital stay (P < .02). Preliminary data indicates an increase in major complications for liver volumes < or = 25% (P = .02). CONCLUSIONS: A simple method of measurement provides an assessment of the liver remnant before resection. It is useful in evaluating response to portal vein embolization and in predicating the outcome before extended liver resections.

Adult↗

[Malignant schwannoma of the breast. A case report].

Malignant schwannoma is a very rare sarcomatous tumor of unknown etiology. Primary mammary localization is exceptional. Clinically, the tumor manifests as an isolated painless nodule visualized as a benign nodule on standard radiogram. Positive diagnosis is provided by pathology. Treatment is surgical. The risk of local recurrence imposes a radical treatment. We report one case and review the literature, underlining the difficulties encountered in diagnosis and emphasizing the recurrent nature of this tumor after conservative treatment.

Adult↗

Gouty tophus simulating soft tissue tumor in a heart transplant recipient.

Gouty arthritis is the most frequent rheumatological complication among cyclosporine-treated organ transplant recipients. We report one case of pseudotumoral intramuscular tophaceous deposit of the forearm, in a heart transplant patient with a history of traumatic wound to the same area 17 years previously, and with no known arthritis.

Adult↗

[Complete non-obstetrical uterine inversion].

A rare case of a gynaecologic uterine inversion is reported emphasizing on the exceptional character of the gynecologic uterine inversion and the pathogenic problems which are tackled. Gynaecologic inversion results from a tumor implanted on fundus of the uterus or from the essential atrophy of suspension ligaments of the uterus. Treatment depends on the anatomic type and the stage.

Adult↗

[Zinc phytotoxicity and induction of stress proteins in bean (Phaseolus vulgaris L.)].

Bean seedlings (Phaseolus vulgaris L., cv. fin de Bagnol) were grown for ten days in nutrient solutions at 0, 50, 100, 500 and 1000 microM ZnS0(4). The results obtained show that Zn treatment is followed by a pathological behaviour, the precocity and intensity of which are dependent on the applied dose. In addition to the depressive effects on the biomass yield and the tissue water content, a decrease in the proteins contents was also observed. Zinc toxicity seems to induce synthesis of low molecular weight proteins in Zn-treated bean stems, but not in the roots and leaves. These peptides, in stems, may protect, hypothetically, the susceptibles metabolic sites in foliar parenchyma against the zinc deleterious effects.

Fabaceae↗

[Struma ovarii. A case report].

Struma ovarii is a rare ovarian tumor composed entirely or in part of thyroid tissue. Pathogenesis is unclear. Diagnosis rests on the histologic study. A case is reported. Specific features of struma ovarii are discussed based on a review of the literature. The treatment is surgical and the outcome generally favorable.

Female↗

[Krukenberg's tumors. 9 cases. Review of the literature].

The authors report a series of nine cases of Krukenberg's tumor, operated at the university clinic of obstetric gynecology (Professor Chaoui) during a period from 1977 to 1990. They underline the metastatic character of this tumor, whose primitive lesion is very often digestive. In most cases, the diagnosis is set late by histological study of the operatory piece, showing the revealing character of this tumor. All the authors agree upon the very dark prognostic of this tumor. The only hope of improvement lies in an extraction as soon as possible of the primitive tumor, followed by a radical treatment of the ovarian tumor. The contribution of complementary treatment is questionable; however, adjuvant chemotherapy keeps a positive efficacy, according to certain authors. The authors deplore one death in keeping with a late diagnosis.

Adult↗