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Biomedical subjects

A Cerillo

Publications and source records attributed to A Cerillo.

At least 19 recordsLinked to original sources
PubMed2001

Neurocysticercosis. Case report.

In the present review we report a case of a 53-year-old woman affected with a cyst solitary cerebral hemispheric lesion causing acute generalized seizure. Clinical and neuroradiologic diagnosis of cystic astrocytoma was performed and the patient was operated. Microscopic analysis of the surgical specimen led to a diagnosis of parasitic infection, consistent with neurocysticercosis (NCC). NCC is the most frequent parasitosis of the central nervous system (CNS) in the world. The infective agent is taenia solium larvae. It is endemic in Latin America, Africa and some Asiatic countries, such as India. In Europe, many cases have been reported in Portugal, Spain, Poland and Romania. In Italy NCC is a rare disease. In recent years no cases have been described, but with high rate of immigration from endemic areas (Africa and East Europe) this parasitosis will be found in our country too, particularly affecting communities where hygienic conditions are poor. In conclusion we briefly analyze the relationship between pathogenesis of this parasitosis and its clinical symptoms.

Cerebral Cortex↗
PubMed1998

Soft cervical disc herniation. An analysis of 187 cases.

METHODS: During the period from January 1986 to December 1994, 187 consecutive patients (102 males and 85 females, between the ages of 24 and 63 years) with soft disc herniations of the cervical spine were operated on by anterior approach. RESULTS: One hundred and twenty-seven (67.9%) patients presented pure radicular syndrome, 17 (9.1%) with pure medullary syndrome, and 43 (23%) with myeloradiculopathy. Disc herniation was at the C3/4 level in 8 (4.3%) cases, at the C4/5 level in 17 (9.1%) cases, at the C5/6 level in 101 (54%) cases, and at the C6/7 level in 87 (46.6%) cases. In 18 (30%) patients suffering from myelopathy (with or without radiculopathy) an area of high MR signal intensity was observed within the cervical cord on T2-weighted images; such area corresponded at the level of cord compression by the herniated disc and was not demonstrated on T1-weighted images. All patients underwent microdiscectomy without bone grafting. Complete or almost complete relief of preoperative symptomatology was observed in 95.6% of patients with radiculopathy and in 83.3% of those with myelopathy.

Adult↗
PubMed1998

Atypical pleomorphic xanthoastrocytoma.

A 65-year-old man experienced an ictal episode. CT revealed a left capsulo-thalamic mass, and SPET showed hypoperfusion of the left cerebral emisphere. The lesion was subtotally removed, and postoperative radiotherapy was given. Pathological examination demonstrated an "atypical" pleomorphic xanthoastrocytoma. The patient died of massive regrowth of the tumor 22 months after surgery. This case is discussed in light of the pertinent literature.

Aged↗
PubMed1998

Myeloradicular damage in traumatic cervical disc herniation.

BACKGROUND: The literature on pure traumatic disc herniation is now voluminous but diversity of opinion exists regarding frequency, pathogenesis and management of this type of lesion. As a further contribution to the solution of the question it is thus justified to report our series of cervical traumatic disc herniation. METHODS: During the period from January 1986 to December 1994, 41 patients (25 males and 16 females, between the ages of 24 and 51 years) with traumatic cervical disc herniations were operated on by anterior approach. Twenty-six (63.4%) patients presented with radicular syndrome, 3 (7.3%) with medullary symptoms and signs, and 12 (29.3%) with myeloradiculopathy. Disc herniation was at the C3/4 level in 4 (9.7%) cases, at the C4/5 level in 7 (17.1%) cases, at the C5/6 level in 24 (58.5%) cases, and at the C6/7 level in 8 (19.5%) cases. In 6 (40%) patients suffering from myelopathy (with or without radiculopathy) an area of high MR signal intensity was observed within the cervical cord on T2-weighted images; such area corresponded at the level of cord compression by disc and was not demonstrated on T1-weighted images. All patients underwent discectomy without bone grafting. RESULTS: Among patients with radiculopathy, 27 (71%) experienced complete relief of preoperative symptomatology, and 11 (29%) minor pain and/or neurological deficits without interference with work activities. The myelopathy completely disappeared in 11 (73.3%) cases whereas remained unchanged in 3 (20%); 1 patient with myelopathy experienced amelioration of preoperative specific symptoms and signs. CONCLUSIONS: The results of surgery for cervical radiculopathy due to traumatic disc herniation are satisfactory since 92 to 100% of the patients postoperatively regain prior activities, an observation we have confirmed with our own series. The results in cases of myelopathy are less satisfactory: although approximately 73% of our patients with myelopathy reported total relief of preoperative symptomatology, published reports indicate that a significant postoperative improvement is seen in 33 to 56% of patients.

Adult↗
PubMed1998

[Posttraumatic syringomyelia. A report of an atypical case].

An atypical case of post-traumatic syringomyelia is reported. Clinical presentation, electrophysiological and MR findings, as well as therapeutic efforts adopted for this case are discussed in the light of pertinent literature.

Cervical Vertebrae↗
PubMed1997

Pleomorphic xanthoastrocytoma: clinical, imaging and pathological features of four cases.

Four cases of pleomorphic xanthoastrocytoma (PXA) were collected from among 688 glioma patients who underwent operation at the Institute of Neurosurgery, University of Naples "Federico II" between January 1973 and December 1994. Three were females and one male, ranging in age from 10 months to 65 years. Three tumors were superficial in location, appearing as a meningo-cerebral mass in the temporo-parietal region. In one case, the tumor was situated deep within the brain (capsulo-thalamic region), without contact with leptomeninges. Three patients had experienced epileptic seizures, whereas one patient presented with an ictal episode. Tumor excision was grossly total in two cases, and subtotal in the remaining two. In three cases, histological examination demonstrated a "typical" PXA; conversely one tumor (subtotal excised) was an "atypical" PXA. The two patients with incomplete surgical resection were postoperatively treated with fractionated brain radiation therapy. Of the two patients who had grossly total removals, one showed tumor recurrence 6 years after surgery, and underwent operation (the recurrent neoplasm did not exhibit malignant transformation); the second patient was free of tumor at 14 months following craniotomy. Of the two patients who had undergone subtotal removals, one died because of massive regrowth of the lesion 22 months after surgery, whereas the second patient was asymptomatic at 1 year follow up.

Adolescent↗
PubMed1997

[The microsurgical treatment of the carpal tunnel syndrome].

Between 1988 and 1994, 101 patients with carpal tunnel syndrome underwent microsurgical treatment. In 69 (68.3%) patients, simple incision of the transverse carpal ligament was performed. The remaining 32 (31.7%) patients also required neurolysis: external neurolysis in 17 (16.8%) patients, both external and internal neurolysis in 15 (14.9%) patients. There were no intra- and postoperative complications. After surgery, preoperative symptoms completely disappeared in 98 (97.1%) patients and improved in 3 (2.9%).

Adult↗
PubMed1995

Supratentorial dermoid cysts. Presentation and management of five cases.

Five patients with supratentorial dermoid cysts who were surgically treated are presented. There were three males and two females, between the ages of 17 and 35 years (mean 26.6 years). The tumor location was frontobasal and/or temporobasal. The duration of illness before the diagnosis ranged from 1 to 14 months (mean 7.4 months). Clinical presentation included seizures, intracranial hypertension syndrome, aseptic meningitis, homonimous lateral hemianopsia, and memory defect. Preoperatively, all patients were investigated by computerized tomography (CT); in two cases, magnetic resonance (MR) imaging was also obtained. Tumor removal was performed by microsurgical procedures; it was total in 3 cases and subtotal in the remaining 2 cases. Histologically, all of the tumors exhibited the typical dermoid cyst pattern. There were no operative deaths. Two patients experienced postoperative language dysfunction and/or hemiparesis. No patient developed clinicoradiological evidence of tumor recurrence at 1 to 10 years (mean 5 years) following surgery. These results are discussed in light of the data previously reported by the literature.

Adolescent↗
PubMed1994

Antibiotic prophylaxis in elective neurosurgery. Epidemiological study.

The authors present an epidemiological study of patients who have undergone elective neurosurgery and who have been treated with different types of antibiotics throughout a ten year time span. From the statistic analysis of the different parameters taken into consideration (administering modalities of the short-term and long-term antibiotic, type of sepsis encountered, isolated microorganisms) the authors show, as a result, that the long-term antibiotic prophylaxis is a clearly improper method; the short-term prophylaxis is a correct method the effect of which is, however, still controversial as it does not modify a natural low percentage of infections in elective neurosurgery. The role given to the antibiotic seems much less important compared with the adoption of correct antiseptic measures and of proper nursing.

Anti-Bacterial Agents↗
PubMed1992

Vascular injury related to lumbar disk surgery.

The authors report a case of left common iliac artery injury, as a complication of diskectomy, in a 57 year-old male patient, with herniated disk at L4-L5. A review shows that L4-L5 disk space is the most common site for this rare complication of lumbar disk surgery.

Hemorrhage↗
PubMed1990

[The role of inflammatory infiltrate as a prognostic criterion in cerebral metastases. Preliminary results].

Data concerning a preliminary study on the prognostic significance of inflammatory infiltration in cerebral metastases are reported. Seventeen cases of operated cerebral metastases have been studied to investigate their histotype and grade of necrosis, stromal reaction, and inflammatory infiltration. Finally, the results obtained are discussed in relation to the postoperative survival rate of the patients.

Brain↗