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Biomedical subjects

A Calvo

Publications and source records attributed to A Calvo.

At least 91 records · Page 5Linked to original sources

Evaluation of the American Rheumatism Association preliminary criteria for remission in rheumatoid arthritis: a prospective study.

This study evaluates the American Rheumatism Association criteria for remission in rheumatoid arthritis (RA) using data gathered prospectively in 2 distinct patient groups: Americans (n = 181) and Peruvians (n = 44). The criteria were found to be highly specific in both patient groups but the sensitivity of the criteria was low in the American patients. The criteria most frequently not satisfied in the American patients with RA were subjective. Several explanations are offered: differences in disease severity, problems in using a translated questionnaire, differences in practice level among rheumatologists, but none of them fully explain the lower sensitivity of the criteria among the American patients.

Adult↗

[Pyometra].

Explore the source record for details and available documents.

Aged↗

[Endocardial cushion defect without ostium primum atrial septal defect associated with tetralogy of Fallot (author's transl)].

A case of endocardial cushion defect without ostium primum atrial septal defect associated with tetralogy of Fallot is presented. The echocardiogram is specially interesting showing two atrioventricular valves recorded simultaneously without an intervening ventricular septum, mitral continuity with the posterior semilunar valve and impossibility of recording the anterior semilunar valve. Findings similar to those of single ventricle with pulmonary stenosis. The anatomopathological findings and their possible embryonic basis are analyzed.

Down Syndrome↗

Approximation of baseline and BrdU-induced SCE frequencies.

In the present paper we have developed a new rationale and an experimental schedule to approximate the frequency of SCEs which occur independently of BrdU incorporation, namely, the baseline frequency of SCEs. The method used includes the analysis of SCE yields in second and third division chromosomes after BrdU-substitution for 1, 2, and/or 3 successive replication rounds in the presence of this thymidine analogue, leading to a set of ten different experimental results. As a result of formulating various mathematical equations and applying them to the data, an accurate estimation of the frequency of baseline (BrdU-independent) and BrdU-induced SCEs, can be made, thus avoiding the difficulties inherent in the current extrapolation methods. The conclusions are that 1) SCEs seem to be formed after DNA synthesis (by exchanging post-replicative DNA portions), but, obviously, very near to the replication fork and 2) that under our experimental conditions about 0.065 SCEs per picogram of DNA per cell cycle occur as a consequence of chromosome replication, this frequency being increased by BrdU-substitution. The methodology seems to be reliable enough to be used in other species and systems in order to compare baseline SCE frequencies.

Animals↗

Air-borne fungi in the air of Barcelona (Spain). III. The genus Aspergillus Link.

During a survey on the presence of species of the genus Aspergillus in the air of the city of Barcelona (Spain), the following species were identified: Aspergillus flavus Link, A. niger van Tieghem, A. fumigatus Fresenius, A. clavatus Desmazières, A. terreus Thom, A. chevalieri (Mang.) Thom et Church, A. niveus Bloch, emend. Thom et Church, A. ochraceus Wilhelm, A. versicolor (Vuillemin) Tiraboschi, and A. amstelodami (Mang.) Church et Thom.

Air Microbiology↗

[Termino-lateral anastomosis of the carotid of the rat. Histological evaluation of permeability in relation to the number of suture stitches and the thread used].

A histological study of end-to-side anastomosis on the carotid arteries of the rat, is presented comparing the results according to the type of suture material and the number of stitches. Two groups of 5 animals were studied. Group "A" in which the 11-0 monofilament nylon (18 microns; needle of 70 microns) was utilized with an average of 11 stitches; and group "B" corresponding to the 10-0 nylon (25 microns; needle of 100 microns) with an average of 8 stitches. The patency of the anastomosis was ascertain in all cases except one where a complete thrombosis of the donor artery was discovered. The fact that there were no difference between both groups is stressed. Other findings were: dehiscence, 3; invagination, 3; partial thrombosis, 4 in spite of actual patency. It was concluded that the 10-0 nylon is easier to handle, and 8 stitches are enough to perform and end-to-side anastomosis in 1mm diameter arteries. A regular distance among the stitches and a balanced tension of knotting are important to prevent or to diminish the risk of dehiscence, first range factor of occlusive thrombosis.

Carotid Arteries↗

[Tumors of the sellar region and the cavernous sinus. Evaluation of diagnostic procedures and therapeutic orientation].

Two cases of infrequently seen tumors of the cavernous sinus and the clivus regions are presented. One of them was a chordoma and the other, a myeloma, and both were approached by the transphenoidal route. The clinical picture and the diagnostic procedures are reviewed, and the several surgical approaches to these regions are discussed. These regional processes should be submitted to a precise radiological evaluation: plain skull films, conventional tomography, arteriography, and computerized tomography scan, in order to establish their origin and their extension, and also to determine the proper approach. The authors conclude that all these regional tumors must be operated on, and that the transphenoidal approach is the most effective. This approach is extradural, well known through the experience brought about by the pituitary surgery, and with a low morbi-mortality rate.

Adult↗

[Dysplastic gangliocytoma of the cerebellum or Lhermittee-Duclos disease].

Lhermitte-Duclós disease is an infrequent condition of which there are only 37 cases described in the literature. Although presently considered as a displasic process, its clinical presentation is of a typical posterior fossa tumour and should be treated as such. Even though it is a benign growth there are only 7 cases described with postoperative survival. The uniform pathological anatomy in all the cases presented makes the definitive diagnosis. The authors present a new case with postoperative survival and discuss its clinical presentation, treatment and origin of the disease.

Adult↗

[Quantitative measurement of red cell antigens with Groupamatic].

Groupamatic 360 can be adapted to the quantitative measurement of erythrocyte agglutination reactions. Here the authors give the necessary conditions to obtain the best sensitivity and the best reproductibility. They have considered globular suspensions, incubation of the erythrocyte antiserums mixtures, centrifugation, agitation, photometric measurement. As concerns the quantitative technique, we used the average peripheral measurement obtained in the twleve cuvettes of the same selected disc sector. The calibration is fixed to 50 mV for a non agglutinated red cell suspension and to 950 mV for albumin in a saline solution. In these conditions, the best discrimination is obtained for agglutination with measures between 400 and 800 mV. The maximum sensitivity is reached with reactions corresponding to 600 mV, that is to say in our selected conditions with 50% of free red cells. The choice of the zone between 500 and 600 mV enables to detect variations from 1.5 to 2% in an antibody solution concentration. This zone is particularly favorable for quantitative work. Although a part of these operations in this preliminary work were manually effected, the automatic centrifugation, agitation, photometric measurement and results print out make possible a large number of measurements with very satisfactory reproductibility conditions. Besides, these experiments pointed out some factors of improvement which will be helpful for the new 360 G Groupmatic equipments.

ABO Blood-Group System↗

[Abdominal complications of the ventriculo peritoneal derivations].

Thirty-nine ventriculo-peritoneal shunts in children have been analyzed since 1962 to 1976 at the Neurological Institute in Montevideo. In these cases there were 8 important abdominal complications (20%): 7 were associated with ventriculitis, all with infiltration or fistula on the trajet, 3 cases were operated on because of intestinal occlusion, 1 of them with perforative acute peritonitis. In the others, gastric distention, abdominal distention, and transient ileus were found. Five patients died, 4 of them with ventriculitis, 3 children who had suffered ventriculitis, survived. They overcame their hydrocephalus by means of ventriculo-atrial shunts, afterwards their infection was cured. From the result of the test of these cases it is gathered in view of a ventriculo-peritoneal shunt disfunction, that it is necessary to: 1) As far as possible rule out ventriculitis. 2) In cases in which ventriculitis should be proved to exist and with a peritoneal reject, after the infection has been cured, one should not insist with the ventriculo-peritoneal diversion, because in this case the possibility of the relapse taking into account the abdominal intolerance, increases. After the ventriculitis should be got over with a proper bacteriological control, a ventriculo-atrial shunt must be performed. 3) The changing of the form of the divertion system is considered immediately after an abdominal aseptic intolerance is present (ileus, ascites, etc.), due to the double risk of intestinal occlusion or ventriculitis.

Cerebrospinal Fluid Shunts↗