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Biomedical subjects

A Buchner

Publications and source records attributed to A Buchner.

At least 127 records · Page 7Linked to original sources
PubMed1981

Verruciform xanthoma of the oral mucosa. Report of five cases and review of the literature.

Verruciform xanthoma is an uncommon lesion confined mainly to the oral mucosa. Only two extraoral cases have been reported, and these involved the genitalia. Clinically, verruciform xanthoma is a raised lesion with a papillary or granular surface, usually located on the gingiva or alveolar mucosa. Microscopically, it is characterized by epithelial cell proliferation and by the accumulation of xanthoma cells in the upper lamina propria. Five new cases are reported and analyzed together with an additional 29 cases found in a review of the literature.

Adult↗
PubMed1980

Elastosis in benign and malignant salivary gland tumors. A histochemical and ultrastructural study.

One hundred sixteen cases of various types of salivary gland tumors were examined for the presence of elastic tissue. Almost all the pleomorphic adenomas (97%) and all the malignant pleomorphic adenomas contained elastic tissue in varying amounts. A high percentage (82%) of adenoid cystic carcinomas also contained elastic tissue but the overall quantity was significantly less than in pleomorphic adenomas. All other salivary gland tumors studied, i.e. adenolymphomas, oxyphilic adenomas, mucoepidermoid tumor, and various variants of monomorphic adenomas, were devoid of significant elastic tissue. At the ultrastructural level, the elastic fibers were mainly seen close to neoplastic myoepithelial-like cells, and all stages of elastogenesis were present, ranging from young elastic fibers with a high microfibrilelastin ratio, usually associated with basal-membrane-like material, to mature fibers consisting mainly of an amorphous electron lucent central elastin component. It is postulated that elastic tissue in the salivary gland tumors is produced by the myoepithelial-like tumor cells rather than by tumor stromal induction as has been described in some types of breast carcinomas.

Adenolymphoma↗
PubMed1980

Langerhans' cells in a pleomorphic adenoma of submandibular salivary gland.

Large numbers of round and dendritic cells similar to Langerhans' cells of normal epidermis and other epithelia were seen within a pleomorphic adenoma of the submandibular salivary gland. These cells, which were present only in areas of non-cornifying epidermoid metaplasia, exhibited Birbeck granules with isolated terminal vesicles, cytoplasmic microfilaments, microtubules, and a few poorly developed intercellular junctions.

Adenoma, Pleomorphic↗
PubMed1980

Pigmented nevi of the oral mucosa: a clinicopathologic study of 32 new cases and review of 75 cases from the literature. Part II. Analysis of 107 cases.

Review and analysis of data of seventy-five cases from the literature, together with an additional thirty-two new cases, revealed that nevi of the oral mucosa are not rare and may be more common than previously thought. Nevi of the intramucosal type are the most common, followed by the common blue nevus. Compound nevi are uncommon, and junctional nevi are very rare. The data are analyzed as to the location, presence of clinical pigmentation, configuration, size, and duration of the nevi, as well as the patient's age, sex, and race. Oral nevi (especially those that are clinically nonpigmented) are often misdiagnosed, indicating that they are far more common than they would seem from the reported cases. The potential for oral nevi to undergo malignant transformation is unclear because of the paucity of cases and limited follow-up. Nevertheless, we recommend that all oral pigmented nevi be removed.

Adolescent↗
PubMed1980

Histopathologic spectrum of oral erythema multiforme.

The histopathologic tissue patterns found in twenty-five patients with oral erythema multiforme were as variable as the clinical appearances. The biopsies served an important role in ruling out malignancy, dysplasia, and other classified diseases. While all of the specimens were designated as showing nonspecific inflammatory reactions, in many biopsy specimens there were sufficient characteristic connective tissue and epithelial changes to suggest a tissue diagnosis consistent with the clinical diagnosis of erythema multiforme.

Adult↗
PubMed1980

Angiolymphoid hyperplasia with eosinophilia (Kimura's disease).

Angiolymphoid hyperplasia with eosinophilia (Kimura's disease) primarily affects the skin of the head and neck and the oral mucosa. While the clinical picture is nonspecific, the variable microscopic tissue pattern often is diagnostic. The etiology is unknown, and treatment is unpredictable. A case is presented in which Kumura's disease was not suspected clinically prior to the biopsy. The patient responded to topical fluocinonide, and there was no evidence of an immunologic defect.

Adolescent↗
PubMed1980

Amalgam pigmentation (amalgam tattoo) of the oral mucosa. A clinicopathologic study of 268 cases.

A series of 268 cases of amalgam tattoo is analyzed both clinically and histologically. The most common location was the gingiva and alveolar mucosa, followed by the buccal mucosa. Histologically, the amalgam was present in the tissues as discrete, fine, dark granules and as irregular solid fragments. The dark granules were arranged mainly along collagen bundles and around blood vessels. They were also associated with the walls of blood vessels, nerve sheaths, elastic fibers, basement membranes of mucosal epithelium, striated muscle fibers, and acini of minor salivary glands. Dark granules were also present intracellularly within macrophages, multinucleated giant cells, endothelial cells, and fibroblasts. Although in 45% of the cases there was no tissue reaction to the amalgam, in 17% there was a macrophagic reaction and in 38% there was a chronic inflammatory response, usually in the form of a foreign body granuloma, with multinucleated giant cells of the foreign body and Langhans types. Asteroid bodies were also found in some of the foreign body giant cells.

Adolescent↗
PubMed1980

Reactive lesions of the gingiva. A clinicopathological study of 741 cases.

A series of 741 consecutive cases of localized hyperplastic lesions of the gingiva were studied. The lesions were reclassified into four groups: pyogenic granuloma, peripheral giant cell granuloma, fibrous hyperplasia and peripheral fibroma with calcification. This study indicates that there are some differences between these groups in age and sex distribution as well as in location and size of the lesion. Fibrous hyperplasia was the most common type, followed in descending order by pyogenic granuloma, peripheral fibroma with calcification and peripheral giant cell granuloma. The peripheral giant cell granuloma showed no sex predilection while fibrous hyperplasia, pyogenic granuloma and peripheral fibroma with calcification were more common in females. Pyogenic granuloma and peripheral fibroma with calcification occur in younger patients more often than fibrous hyperplasia, and thus may represent a stage in the development of fibrous hyperplasia.

Adolescent↗
PubMed1980

Metastatic renal cell carcinoma in the gingiva mimicking a hyperplastic lesion. Case report.

An unusual case of metastatic cell carcinoma in the gingiva, without roentgenographic evidence of underlying bone involvement, is described. The tumor had the clinical appearance of a pyogenic granuloma and peripheral giant cell granuloma. Histologic sections and the pertinent history revealed the tumor to be a metastatic renal cell carcinoma. Review of the literature reveals that metastatic lesions to the gingiva are rare, but when they occur they tend to mimic clinically the common localized hyperplastic lesions of the gingiva.

Adenocarcinoma↗
PubMed1980

The application of tetracyclines in forensic dentistry.

Therapeutic administration of tetracyclines, widely used antibiotic drugs, permanently labels layers of dentin that are calcifying at the same time. A method is described for detecting and photographing these stained layers of dentin. The presence of tetracycline-labeled dentin layers in the teeth of subjects of a forensic science investigation can be used for the individualization of specimens as well as to provide information about the age of the individual. When compared to medical records, the tetracycline-labeled dentin layers can also assist in establishing the identity of the subject. The interpretation of tetracycline-labeled dentin layers and its pitfalls are discussed.

Age Factors↗
PubMed1980

Gustafson's method for age determination from teeth--a modification for the use of dentists in identification teams.

Gustafson's method for age determination from teeth is based on the evaluation of ground sections of teeth. Six age-associated parameters are evaluated in the ground section and are compared to a regression curve of age versus the age-associated changes. Two of these changes, transparency of radicular dentin and secondary dentin, have the highest correlation with age. The evaluation of these parameters only from thin (0.25-mm) ground sections may lead to an artificially high "secondary dentin value." These artifacts may be caused by the attempt to include the whole pulp chamber and root canal in a 0.25-mm-thick ground section and by an accidental overgrinding of the apical area of the root, respectively. These artifacts were encountered occasionally even in ground sections prepared by highly trained personnel and became more frequent in ground sections prepared by a person who, though trained, did not use this technique daily. A modification of the data-collecting method is suggested to make possible the use of thick (1.0-mm) ground sections for the evaluation of most of the aging criteria, thereby eliminating the possible inaccuracies in the preparation and evaluation of the thin (0.25-mm) ground sections.

Age Determination by Teeth↗
PubMed1979

Melanotic macule of the oral mucosa. A clinicopathologic study of 105 cases.

A series of 105 cases of melanotic macule of the oral mucosa is analyzed, both clinically and histologically. In most patients the melanotic macule was a solitary lesion, and the most common location was the vermilion border, followed by the gingiva. Histologically, the melanotic macule is characterized by increased pigmentation in either the basal-cell layer, the lamina propria (mainly within melanophages), or in both locations. It is suggested that the term melanotic macule be reserved for lesions in which there is a definite clinicopathologic correlation between a clinically pigmented macule and the aforementioned histologic features and that the term focal melanosis be used only as a histologic designation when these features appear in clinically nonpigmented pathologic conditions.

Adolescent↗
PubMed1979

Pigmented nevi of the oral mucosa: a clinicopathologic study of 32 new cases and review of 75 cases from the literature. Part I. A clinicopathologic study of 32 new cases.

Pigmented nevi are much less common in the oral cavity than they are in the skin. The present study adds thirty-two new cases to the literature. The most common type of nevus was found to be the intramucosal, followed in decreasing order by the common blue nevus, compound nevus, and junctional nevus. The clinical and histologic features of the nevi are analyzed and discussed.

Adolescent↗
PubMed1979

The histomorphologic spectrum of the gingival cyst in the adult.

Gingival cysts with clinical manifestations are relatively uncommon lesions. The present study adds thirty-three new cases to the literature and analyzes their clinical and histologic features. The mandibular cuspid and first premolar region was found to be the most common location. The epithelial lining of the cysts was of several types. The most common type was a thin, flattened lining with or without localized thickenings (buds). Other types included nonkeratinized stratified squamous epithelium, keratinized stratified squamous epithelium, and parakeratinized epithelium with palisading basal cells. Gingival cysts should be distinguished from lateral periodontal cysts on the basis of their origin in the gingiva rather than in bone. It appears that most gingival cysts with clinical manifestations are of odontogenic origin.

Adolescent↗
PubMed1979

Unilateral enlargement of the masseter muscle.

Benign hypertrophy of the masseter muscle is a relatively uncommon condition which may occur unilaterally or bilaterally. The etiology of the ailment is unclear in the majority of cases, and the histopathological features are usually those of normal muscle. A case of unilateral masseter muscle enlargement is described in a 19-year-old Arab male. The histopathological findings were compatible with a mild myopathic disorder. The characteristics, differential diagnosis, etiology, treatment and histopathological features of masserteric hypertrophy are discussed.

Adult↗
PubMed1979

Lipofuscin in human tongue muscle.

In a study of 107 tongue specimens lipofuscin granules were found to be present in the muscle fibers of 93% of the cases. The pigment was not found in young individuals under the age of 18 years. The pigmented granules, which were stored in clusters of different sizes at the nuclear poles, were PAS-positive, stained black or brown with the Masson-Fontana procedure, black with Sudan black, and strong purple-pink with Ziehl-Neelson staining; yellow autofluorescene was emitted in ultraviolet light. The morphology, histochemical reactions and autofluorescence of the pigmented granules were characteristics of the endogenous lipid pigment described as lipofuscin. Statistical analyses indicated a direct correlation between increase in quantity and distribution of the pigment and increase in age (P = 0.001), in both males and females. Accumulation of the pigment in the tongue with aging was found to be similar to that in the myocardium.

Adolescent↗