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Biomedical subjects

A Buchner

Publications and source records attributed to A Buchner.

At least 91 records · Page 5Linked to original sources
PubMed1990

Bone formation in peripheral giant cell granuloma.

Mineralized products were analyzed in a series of 62 cases of peripheral giant cell granuloma of the gingiva or alveolar ridge of man. Histologic sections were examined by routine light microscopy and under polarized light to assess the extent and composition of mineralized tissues in these lesions. In 35% of the cases, mineralized tissue was identified in the form of woven and/or lamellar bone and dystrophic calcification. The most common type was the woven bone which appeared alone or in combination with lamellar bone in 82% of the lesions containing mineralized material. Unlike peripheral ossifying fibroma, no cementum-like material was identified in peripheral giant cell granuloma.

Adolescent↗
PubMed1990

The retrocuspid papilla of the mandibular lingual gingiva.

The retrocuspid papilla (RCP) is a circumscribed nodule that lies lingual to the mandibular cuspid on the gingival tissue. RCP is observed more frequently in young children and seems to regress or disappear with age. Little information is available in the literature on this entity and there are contradictory reports regarding its histologic features. Histomorphologic analysis of 30 specimens diagnosed as RCP revealed that in most cases (80%) it is composed of loosely-arranged delicate fibrous connective tissue with stellate and multinucleated fibroblasts. Elongation of the rete ridges and/or increased vascularity are also present in a significant number of cases. Stellate and multinucleated fibroblasts are not unique to RCP and they have been described as prominent histologic features in other lesions of skin and mucous membrane. RCP is considered to be a "normal anatomical structure" or an "anatomic variation" of the gingiva. The clinical significance of RCP is that it may simulate pathological gingival conditions from which it must be differentiated.

Adolescent↗
PubMed1989

Touton-like giant cells in periapical granulomas.

Two types of multinucleated giant cells were observed in periapical granulomas--the foreign body type and the Touton type. In the Touton type, the nuclei were near the center of the cell, surrounded by foamy cytoplasm. Both types of giant cells reacted positively to lysozyme, alpha 1-antitrypsin and alpha 1-antichymotrypsin, indicating their histiocytic origin.

Giant Cells↗
PubMed1989

Myofibroblasts in peripheral giant cell granuloma. Light and electron microscopic study.

Myofibroblasts are found in various pathologic conditions including lesions containing giant cells, such as central giant cell granuloma and the giant cell tumor of tendon sheath (nodular tendosynovitis). In the present study, myofibroblasts were found in peripheral giant cell granuloma (PGCG) using the TP-Levanol fast cyanine 5RN histochemical procedure and electron microscopy. A number of myofibroblasts displayed intracellular collagen fibrils. The presence of myofibroblasts supports the reactive nature of PGCG.

Fibroblasts↗
PubMed1989

Peripheral odontogenic fibroma. Report of 5 cases.

The peripheral odontogenic fibroma (WHO type) is a relatively rare, benign, unencapsulated, exophytic gingival mass of fibrous connective tissue. Odontogenic epithelium is found within the gingival mass, but usually appears to play a minor role when compared to the fibrous component. According to the present concept, cases reported in the literature under the terms "odontogenic gingival epithelial harmartoma" "hamartoma of the dental lamina" and "peripheral ameloblastic fibrodentinoma" are actually examples of peripheral odontogenic fibroma. Review of the literature revealed only 30 acceptable cases that fit the present concept of peripheral odontogenic fibroma. Because of the paucity of reported cases, the histomorphological spectrum and the clinical features of this lesion have not yet been fully established. This article presents five new cases of peripheral odontogenic fibroma. The connective tissue ranged from markedly cellular to relatively acellular well collagenized. Islands and strands of epithelium were present in all five cases: in four they were scanty and in one abundant. A matrix of mineralized material was present in four cases. The peripheral odontogenic fibroma must be differentiated histologically from peripheral ossifying fibroma, which is a reactive lesion, and from the peripheral ameloblastoma and the calcifying epithelial odontogenic tumour.

Adult↗
PubMed1989

Ancient neurilemmoma (Schwannoma) of the oral cavity.

Ancient neurilemmoma is a rare lesion of the oral cavity. The present article describes an additional case and discusses some difficulties in its histological diagnosis. The final diagnosis is based on both light and electron microscopy morphology. Immunohistochemical studies are, at present, only of supportive value.

Female↗
PubMed1989

Detection of human papillomavirus (HPV) DNA in focal epithelial hyperplasia.

Five focal epithelial hyperplasia (FEH) specimens from four patients were examined by Southern blot hybridization analysis to determine the specific human papillomavirus (HPV) types present. The histomorphologic features of these specimens were also evaluated and a broad variety of changes including koilocytes, mitosoid cells, ballooning cells and cells showing individual cell keratinization were noted. FEH lesions from the three patients sharing a familial relationship demonstrated HPV DNA sequences that were either the prototype HPV-13 or a very closely related HPV-13 subtype. These patients also showed similar clinical features. Lesional tissue from the other patient was found to harbor HPV DNA sequences similar to HPV-32. In view of these findings it is suggested that these specific HPV types are associated with the characteristic FEH histomorphology described.

Adolescent↗
PubMed1988

Lipid pigment (lipofuscin) in human perioral muscles with aging.

In a study of 80 perioral muscle specimens, lipid pigment (Lipofuscin) granules were present in 68.5% of the cases. The pigmented granules, which were stored at the nuclear poles, were PAS positive, stained black or brown with the Masson-Fontana procedure, black with Sudan black and strong purple-pink with Ziehl-Neelsen staining; yellow autofluorescence was emitted in ultraviolet light. The morphology, histochemical reactions and autofluorescence of the pigmented granules were characteristics of the endogenous lipid pigment--lipofuscin. Statistical analyses indicated a direct correlation between increase in quantity and distribution of the pigment and increase in age (p less than 0.0001), in both males and females. Accumulation of the pigment in the perioral muscles with aging was found to be similar to that in the myocardium and tongue muscles.

Aging↗
PubMed1988

Cholesterol granuloma of the jaws. Report of a case.

A case of a cholesterol granuloma of the mandible, which manifested as a solitary radiolucent lesion in an edentulous area, is presented. There is a lack of accurate data regarding its nomenclature and pathogenesis. In this report, the literature is reviewed, the nomenclature is clarified and the pathogenesis discussed.

Cholesterol↗
PubMed1988

The peripheral odontogenic keratocyst.

A case with a firm asymptomatic nodule of 1 cm diameter on the gingiva between the left upper cuspid and first bicuspid is presented. Radiographic examination did not reveal any pathology of the bone in that region. Histologic examination revealed a cyst wall lined by squamous stratified epithelium, characteristic to the lining of an odontogenic keratocyst. It is suggested that the term peripheral odontogenic keratocyst be used for the diagnosis of this lesion.

Adult↗
PubMed1987

Peripheral odontogenic fibroma.

Peripheral odontogenic fibroma (WHO type) is an uncommon lesion of the gingiva; 18 well-documented cases have been published. It is considered to be the extraosseous counterpart of the central odontogenic fibroma. Because of the paucity of reported cases, the full histomorphologic spectrum of this lesion has not yet been established. This article presents nine cases of peripheral odontogenic fibroma that illustrate the variety of its histopathologic findings. The connective tissue ranged from loose (almost myxomatous) to markedly cellular to relatively acellular and well-collagenized. Islands and/or strands of odontogenic epithelium were present in all lesions. Matrix of mineralized material was present in three cases, and juxtaepithelial hyalinization was seen in one case. To avoid the introduction of additional diagnostic terms, we suggest that all these lesions be considered a spectrum of the peripheral odontogenic fibroma (WHO type). We also suggest that the term WHO type be used to distinguish peripheral odontogenic fibromas from the peripheral ossifying fibroma with which they have often been confused.

Adolescent↗
PubMed1987

Pigmented nevi of the oral mucosa: a clinicopathologic study of 36 new cases and review of 155 cases from the literature. Part I: A clinicopathologic study of 36 new cases.

Pigmented nevi are uncommon oral lesions. This study adds data on 36 new cases. The most common type of nevus was the intramucosal type (20 cases), followed by the common blue nevus (11 cases). Only three cases were of the compound type and only two were of the junctional type. The hard palate was the most frequent location for the blue nevus, whereas the buccal mucosa was the most frequent site for the intramucosal nevus. One nevus (intramucosal type) was located on the tongue, and to our knowledge, this is the first reported example of pigmented nevus at this site. The individual data on the 36 cases are presented and compared with a previous study on oral nevi from the University of California at San Francisco. The previously unpublished clinical details on the 32 nevi from the previous study are also presented.

Adolescent↗
PubMed1987

The histomorphologic spectrum of peripheral ossifying fibroma.

A series of 207 cases of peripheral ossifying fibroma was analyzed both clinically and histologically. Almost 60% of the lesions occurred in the maxilla, and in both jaws more than 50% occurred in the incisor-cuspid region. The lesion was most common in the second decade. Females were affected more frequently than males; the ratio was 1.7:1. The recurrence rate--16%--was relatively high. Histologically, in 66% of the cases the surface epithelium was ulcerated and in the remainder it was intact. The ulcerated lesions were composed of highly cellular fibroblastic connective tissue, whereas in the nonulcerated lesions part of the tissue was more collagenized. Both types contained mineralized products in the form of bone, cementum-like material, and/or a dystrophic type of calcification. The dystrophic calcification was most prevalent in the ulcerated lesions. The mean duration at time of excision for the ulcerated lesions was 5.6 months and for the nonulcerated lesions was 24 months. It is proposed that the ulcerated and nonulcerated lesions represent a spectrum of one lesion with different stages of maturation.

Adolescent↗
PubMed1987

Pigmented nevi of the oral mucosa: a clinicopathologic study of 36 new cases and review of 155 cases from the literature. Part II: Analysis of 191 cases.

Review and analysis of data on 191 cases of oral pigmented nevi from the literature and from two studies at the University of California, San Francisco, revealed that nevi of the intramucosal type are the most common, followed by the common blue nevus. Compound and junctional nevi are rare, and combined nevi are the rarest. The data on location, presence of clinical pigmentation, configuration, size, and duration of the nevi, as well as on the patient's age, sex, and race, are analyzed. Blue nevi were found mostly on the hard palate, whereas intramucosal nevi occurred on the buccal mucosa, on the gingiva, and on the lips as well as on the palate. Nonpigmented nevi were especially common (22%) in the intramucosal group. Most oral nevi are raised, which can be of help in the differential diagnosis. Oral nevi are small, most being between 0.1 and 0.6 cm at the largest dimension. Because the malignant potential of oral nevi is still uncertain and because preexisting macular pigmentation is present in about one third of all patients with oral melanoma, it is advisable to accurately diagnose all oral pigmented lesions, many of which will require microscopic examination.

Adolescent↗
PubMed1987

Peripheral epithelial odontogenic tumors: a review.

Peripheral (extraosseous or soft tissue) odontogenic tumors are rare lesions that occur in the soft tissue overlying the tooth-bearing areas of the mandible and the maxilla. A review of the English-language literature revealed only 48 well-documented cases of peripheral epithelial odontogenic tumors. Thirty-two were peripheral ameloblastomas; six were peripheral adenomatoid odontogenic tumors; nine were peripheral calcifying epithelial odontogenic tumors; and one was a peripheral squamous odontogenic tumor. An additional four cases were reported as peripheral ameloblastomas in extragingival locations, but their odontogenic origin is debatable. Although the peripheral ameloblastoma is histologically similar to its central counterpart, it differs in its clinical features and biologic behavior. It does not exhibit an aggressive, destructive behavior and does not invade the underlying bone. Conservative excision of the tumor with minimal but adequate margins is the treatment of choice and recurrences are uncommon. This benign biologic behavior appears to be true also for lesions diagnosed as peripheral calcifying epithelial odontogenic tumors and undoubtedly is true for the peripheral adenomatoid odontogenic tumors.

Gingival Neoplasms↗
PubMed1986

The retrocuspid papillae in Israeli Jews.

The prevalence of an anatomic variation, called retrocuspid papilla, was determined in Israeli Jews. The distribution of the retrocuspid papillae, according to two age groups, and symmetry within the dental arch and in relation to ethnic origin were examined. Results showed that retrocuspid papillae were observed in 38.5% of the young group and in 11.3% of the adult group. Greater occurrence of bilateral than unilateral retrocuspid papillae was observed in each age group and in both sexes. No significant ethnic trend was found when the prevalence of retrocuspid papillae was examined in relation to the ethnic origin of the study sample.

Adolescent↗