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Biomedical subjects

A Bosch

Publications and source records attributed to A Bosch.

At least 145 records · Page 8Linked to original sources

Anaplastic seminoma.

Eight patients with the diagnosis of anaplastic seminoma of the testicle were treated during the megavoltage era from January 1959 to January 1976. Two patients with Stage I disease and one patient with Stage IV disease have died from their malignancy. By contrast, 57 patients with typical seminoma were treated during the same interval and with the same treatment methods. However, only two patients with typical seminoma have died. One of these patients had Stage II disease and one had Stage IV disease. There were no deaths among patients with Stage I typical seminoma. These results suggest that anaplastic seminoma has a poorer prognosis than typical seminoma even when the diseases are compared stage for stage. Implications for therapy are discussed.

Adult↗

Complications after radiation therapy for cervical carcinoma.

A series of 1 139 patients with invasive carcinoma of the cervix uteri who received a complete course of treatment by means of external irradiation followed by intracavitary curietherapy was evaluated in order to assess the results of treatment and, in particular, the radiation complications induced. Complications developed in 145 instances (12.7%). Severe complications occurred in only 3 per cent. Twenty-four cases had more than one complication. Rectosigmoidal injuries accounted for 72 per cent of all complications, and appeared earlier than did bladder complications and within the first two years after treatment. No apparent correlation between age and the occurrence of complications was found. The rate was higher in early stages. The radiation complications did not adversely affect the survival results.

Colitis↗

Staging laparotomy and survival in carcinoma of the uterine cervix.

Pretreatment staging laparotomy in carcinoma of the uterine cervix has been advocated because surgical staging may detect disease not apparent clinically. An analysis of survival and local control data from previously reported large series of patients with carcinoma of the uterine cervix shows that surgical staging does not increase survival rates. It is likely that surgical staging may also increase morbidity from therapy.

Evaluation Studies as Topic↗

Cancer of the nasal cavity.

The experience with 40 consecutive cases of cancer of the nasal cavity seen over a period of 15 years is presented. Males outnumbered females in a ratio or 5 to 3. Age ranged from 35 to 88 years, and the median age was 67 years. Epidermoid carcinoma accounted for 78% of the cases. Smoking from early age was a noticeable habit among these patients. The median length of smoking history was 51 years. Most lesions were diagnosed in an advanced stage of the disease, 58% of the cases being T3 lesions. Regional lymph nodes metastases were infrequent; only 12% of the patients presented nodes on admission; another 5% developed metastatic nodes during the follow-up period. An overall 5-year survival of 56% was obtained. The survival of cases with T1N0 lesions was 91%. Radiation therapy was the treatment of choice employed in 85% of the cases. A 5-year survival of 50% was obtained in these patients. Irradiation offers an additional means of salvaging recurrences after surgery. The special characteristics of tumors of the nasal cavity merit the evaluation of such lesions separately from tumors of the paranasal sinuses.

Adult↗