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A Bordeianu

Publications and source records attributed to A Bordeianu.

At least 73 records · Page 4Linked to original sources
PubMedDate not supplied

Histochemical alterations in the digestive tract of rats after 13 days of flight in the "Cosmos 1887" biosatellite.

In rats recovered after 13 days of cosmic flight a diminution of acid and neutral glycoproteins was observed in the gastric mucosa and proximal segments of the small intestine: the decrease was less evident in the sublingual glands and colon. Leucine aminopeptidase and acid phosphatase in the small intestine were intensified. No significant changes were observed in the other enzymes investigated. Acid phosphatase showed a more intense activity in the endocrine pancreas B cells. The alterations observed after 13 days of flight in the "Cosmos 1887" biosatellite are significant but less marked than after 18 days of flight, and more accentuated than after 5-7 days of flight.

Animals↗
PubMedDate not supplied

Effects of a seven-day hypokinesia on the digestive tract of nonpregnant and pregnant rats.

Hypokinesia (HK) produced by a 7-day contention of pregnant rats in small cages is followed by a discrete decrease of PAS reaction for glycoproteins in the submandibular and sublingual glands, in the mucosa of the stomach, duodenum, small intestine and colon, and also by a small but evident increase of that for leucineaminopeptidase and acid phosphatase in the duodenum and in the intestine. The moderation of these reactions may be explained by the small interval of contention, and not by pregnancy, because the changes are similar in male rats after the same interval. After a longer interval, these reactions change in the same manner but they are more evident, as results from our previous studies. They are not connected with a corticosterone hypersecretion (the principal glucocorticoid in rat) because adrenalectomy does not influence them as results from our previous research. HK increases the 4 and 5 isoenzymes of lactic dehydrogenase (LDH) in the stomach. In the small intestine appeared only the LDH 4 and 5 isoenzymes, HK increases LDH5 isoenzyme. Adrenalectomy increases all LDH isoenzymes of gastric mucosa, and in the small intestine all five fractions appeared, but with a slight activity of LDH 1 and 2. This relation between adrenal hormones and these isoenzymes must be further studied, especially after HK. After a 7-day HK, nonpregnant female rats present an augmented total gastric acid output (TAO), as previously found by us in males. After adrenalectomy this acid hypersecretion disappeared. Even smaller values for TAO were found. Pregnancy considerably increased TAO which may be due, as we have already found, to a blood pH decrease. After HK this hypersecretion decreased remaining nevertheless great. Progeni born of rats submitted to HK have, after 30 days of life, an augmented TAO. Parts of this research were carried out in order to reproduce by HK, at ground level, the 5-day orbital flight conditions of the soviet Cosmos 1514 biosatellite containing pregnant rats in which we studied some identical parameters.

Acid-Base Equilibrium↗
PubMedDate not supplied

Histochemistry of the gastrointestinal tract in pregnant rats subjected to cosmic flight and in their progeny (Cosmos 1514).

Investigations were carried out in the digestive tract of pregnant rats submitted to 5 days orbital flight, as well as in rats aged 30 and 100 days, to which the pregnant experimental rats had given birth. The flight produces, in pregnant rats, a mild reduction of the glycoproteins of the salivary glands, of the gastric mucosa and the goblet cells of the small intestine, as well as an augmented activity of some intestinal enzymes. The progeny born after flight presents at 30 days a mild decrease of the glycoproteins in the sublingual gland and stomach and a slight increase in the activity of some enzymes in the small intestine. In 100-day-old rats, the differences between control and experimental group are not significant.

Animals↗
PubMedDate not supplied

The digestive tract of rat after flight in the biosatellite Cosmos 1667.

From the histochemical investigation carried out on the digestive tract of rats after 7 days space flight in the soviet biosatellite Cosmos 1667 it resulted that neutral and acid glycoproteins diminished slightly in the sublingual gland, stomach, small intestine and the colon. Some intestinal enzymes augmented (leucineaminopeptidase, acid phosphatase, adenosinetriphosphatase and glucose-6-phosphatase). The changes observed after this flight were less marked than after an 18 day flight (in the Soviet biosatellite Cosmos 936 and 1129) and similar to those revealed after 7 days of hypokinesia. The glycoprotein changes were close to those observed after a 5-day flight (Cosmos 1514) but in which there were pregnant rats; after these last flights, the enzymes were not studied.

Animals↗