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Biomedical subjects

A Berger

Publications and source records attributed to A Berger.

At least 451 records · Page 25Linked to original sources

[Results following primary nerve sutures].

143 primary nerve sutures in the upper extremity were examined for sensory and motor recovery according to the scheme of Highet (1954). The majority of the patients had digital nerve lesions (72.3%). Different factors were evaluated for their influence on nerve regeneration. Using a standard operative technique static two-point discrimination returns in two thirds of the cases.

Finger Injuries↗

Comparison of early neonatal behavior in two Israeli ethnic groups.

A review of the literature on differences between Israeli children born to parents of North African and of European descent revealed only a few studies concerning child development. Two trends emerged: a) these developmental differences seemed to resolve gradually over time; and b) there appeared to be an early general developmental precocity in the infants of North African descent, while in later childhood, European children generally performed better in all developmental areas. The present study compared the early behavior of 40 second-generation Israeli neonates from these two ethnic groups. The results indicated a few statistically significant behavioral differences between the groups, all in favor of the North African group. The auditory habituation item was dependent on maternal education, a result which may be attributed to genetic and/or intrauterine environmental factors fostering the development of a protective mechanism in a potentially over-stimulatory future environment. The small-scale differences between the neonates of the two ethnic groups may represent the already documented tendency and gradual resolution of interethnic variations and the early North African precocity during infancy.

Africa, Northern↗

[Nerve regeneration in autologous and allogeneic transplant of the sciatic nerve of the rat with and without immunosuppression by cyclosporin A].

The following experimental studies show different stages of regeneration and rejection in autologous and allogenic nerve grafts in 162 rats with and without immunosuppression with Cyclosporin A. Allografts were used in congenic rats differing only in major histocompatibility complex (MHC). Nerve regeneration was studied in autologous grafts with and without treatment with Cy A and with toxic doses of Cy A. No difference in nerve regeneration was seen in these groups. Allografts were transplanted between congenic rats type LEW 1 A and 1 U and vice versa with and without treatment with Cy A. Various degrees of rejection from slight to moderate were seen. Without Cy A-treatment, nerve grafts were totally destroyed after four weeks. With Cy A, nerve grafting resulted in complete regeneration.

Animals↗

[Free vascularized nerve transplants, free donor nerves, suitable donor sites].

The vascularized nerve graft offers an alternative to the conventional free nerve graft. Possible nerves for grafting, the anatomy of the donor sites, and the advantages and disadvantages of vascularized nerve grafts are discussed. The variations in blood supply and the loss of function caused by harvesting play an important role. Clear indications in our opinion are long nerve defects, scar in the wound bed and reconstruction of the brachial plexus. Exact planning, correct indications and good micro-neurovascular technique are all important in neuromicrosurgery and the basis for good results.

Arteries↗

[Soft tissue injuries in the area of the hand].

Soft tissue injuries to the hand are always a problem to the surgeon. A thorough examination and a precise preoperative diagnosis are the most important factors regarding forming a treatment concept. Blood supply, sensitivity and additional injuries are especially important parameters. The modern methods of plastic and reconstructive surgery involving tissue transfer and microvascular and even combined reconstruction methods, all offer multiple possibilities for reconstruction--even for problematic soft tissue injuries. The method of determining the urgency (Urgence différée) permits as even to offer patients methods that are normally only useful or successful in the hands of a specialist. Primary treatment can even take place in the first 48-72 h. If adequate operative treatment is performed by a plastic and reconstructive surgeon, the further corrective procedures that are often necessary can often also be avoided.

Amputation, Traumatic↗

[Intercarpal dislocation in early childhood. A case report].

A case of intercarpal subluxation in a six-year old girl is described. The possibility and danger of open reduction is discussed. The potential complications are loss of bone density and growth arrest as a result of an injury sustained early in life.

Carpal Bones↗

[Endoscopic evaluation of a retard cimetidine preparation with reference to its effect in stomach and duodenal ulcer. A comparative study with a non-retard cimetidine preparation].

With the development of this new galenic retard administration, we found in conclusion a significant longer action interval. A dose increase, similar to non retard administrations was on no account necessary. The new drug, Cimetidine retard, offers accordingly the opportunity of full utilization of the offered pharmacologic effective substance in combination with low dose administration and poor side effects.

Cimetidine↗

Quantitative sensory testing demonstrates that subclinical sensory neuropathy is prevalent in patients with cancer.

Vibration threshold (VT) determinations were used to assess the function of the large nerve-fiber sensory system in 171 patients with cancer and 58 healthy subjects. Significant differences in VT indicate dysfunction of this sensory system in the cancer group. Twelve percent of the cancer patients had elevated VT compared with 1.7% of control subjects. Elevated VT was not associated with risk factors for neuropathy such as diabetes, renal disease, poor nutrition, or treatment with chemotherapy. Although VT elevation was associated with alcoholism and increasing age, these variables accounted for only a small proportion of the variance in VT. These data suggest that VT determinations are a useful method for quantifying sensory abnormalities in cancer patients. Sensory abnormalities occur in a significant proportion of patients with cancer and seem to be related directly to the neoplasm, rather than to known risk factors for neuropathy.

Humans↗

[Skin transplantation or artificial skin replacement?].

The closure of big skin defects is still a problem. Autologous skin is not unlimitedly available. Different skin substitutes are invented and available. All of them are suffering one problem. They can only be used for temporary closure. Even the immunological progress can not solve the problem of skin shortage. An interesting artificial skin was designed by Burke and Yannas. They designed an artificial dermis consisting of bovine collagen and chondroitin-6-sulfate. This is a fascinating possibility for solving the skin shortage problem especially in burn cases. But even this dermis needs autologous epithelial cells to create a complete skin coverage. So till now a complete skin substitute without autologous material seems not to be available.

Bandages↗

The usefulness of Doppler echocardiography in the management of rhabdomyoma diagnosed prenatally.

Cardiac rhabdomyoma diagnosed prenatally by cross-sectional echocardiography was confirmed after birth by Doppler echocardiography and cardiac catheterization in a baby with tuberous sclerosis. Doppler echocardiographic follow-up after 2 years revealed regression of tumour masses and concomitant disappearance of pulmonary regurgitation which was caused by the large tumour mass in the right ventricular outflow tract. In spite of a sizeable mass protruding into the left ventricular outflow tract, repeated Doppler examination failed to demonstrate any significant obstruction, thus avoiding repeated catheterizations and unnecessary surgery. Doppler examination of ventricular inflow revealed normal filling characteristics. Doppler and cross-sectional echocardiography was of great value in the management of this patient.

Echocardiography↗