Search PubMed⌕ Search

Biomedical subjects

A Baraka

Publications and source records attributed to A Baraka.

At least 163 records · Page 9Linked to original sources
PubMed1989

Propofol versus thiopentone for induction of anesthesia in patients undergoing outpatient surgery.

Investigation was carried out on 40 females undergoing dilation and curettage or laparoscopy on outpatient basis. All patients were premedicated with pethidine and atropine. In 20 patients, anesthesia was induced with intravenous propofol 2 mg/kg (Group I), and in the other 20 patients thiopentone 4 mg/kg was used (Group II). Prior to induction of anesthesia, 80 mg of lignocaine (4 ml of 2%) was injected intravenously to be followed by the induction agent. No pain followed the injection of propofol or thiopentone and smooth induction of anesthesia was achieved within 60 seconds. Injection of suxamethonium 100 mg and tracheal intubation was then performed and anesthesia was maintained with 66% N2O in O2 supplemented by suxamethonium drip. In the thiopentone group, SBP decreased after induction and tracheal intubation was followed by a significant increase of SBP and HR. In the propofol group, both SBP and HR decreased after induction and tracheal intubation was also followed by an increase of SBP and HR. However, the increase of SBP was less than that observed in the thiopentone group and the increase of HR was not significant when compared to the control value. At the end of surgery and cessation of anesthesia, recovery was scored. After 10 minutes, all patients in the propofol group were awake and initiated conversation while 12 patients of the thiopentone group were still sleepy. The results suggest that propofol may be preferred to thiopentone for induction of anesthesia in outpatient surgery.

Adult↗
PubMed1989

Epidural meperidine for control of autonomic hyperreflexia in a quadriplegic undergoing cystoscopy.

Epidural meperidine was used to control autonomic hyperreflexia (AH) during cystoscopy and transuretheral sphincterotomy, in a quadriplegic patient who had chronic spinal cord transection at C6 level. Meperidine 100 mg diluted in 10 ml saline was injected in the epidural space at L3-L4 level. Within 10 minutes and throughout the surgical procedure, the blood pressure stabilized at 125/70-140/80 mmHg. Epidural meperidine produces selective blockade of the spinal opiate receptors and hence may block the nociceptive reflexes below the level of cord transection and prevent AH.

Autonomic Nervous System Diseases↗
PubMed1988

Severe bradycardia following propofol-suxamethonium sequence.

Anaesthesia was induced with propofol 2.5 mg kg-1 followed by suxamethonium 1.5 mg kg-1 in six young healthy females undergoing laparoscopy. ECG was monitored continuously. In two unpremedicated patients, this was followed by severe sinus bradycardia, while no bradycardia was observed in the other four patients who were premedicated with atropine 0.6 mg i.m. These observations suggest that propofol-suxamethonium sequence may be followed by severe bradycardia in patients who have not received atropine. The bradycardia may be prevented by premedication with atropine. In contrast to thiopentone, propofol apparently lacks central vagolytic activity and may exert a central vagotonic effect which can exaggerate the muscarinic effects of suxamethonium.

Adolescent↗
PubMed1988

Recurarisation following a suxamethonium-alcuronium sequence in patients with atypical cholinesterase.

Alcuronium 10 mg was administered to maintain muscle relaxation in two patients before recovery from suxamethonium neuromuscular blockade to facilitate tracheal intubation. This sequence resulted in a markedly prolonged block which could not be antagonised adequately by neostigmine 0.05 mg/kg; initial antagonism was followed rapidly by prolonged recurarisation. Estimation of plasma cholinesterase activity revealed that the two patients were homozygous for the atypical and silent genes. respectively.

Adult↗
PubMed1988

Differential lung ventilation during thoracotomy.

The effect of differential lung ventilation on arterial PO2 and PCO2 was compared to that achieved during one-lung ventilation in 8 patients undergoing thoracotomy. In all patients, OLV of the dependent lung, while collapsing the nondependent lung, was associated with lowering of the arterial PO2. DLV using a special double-lumen tube adaptor was then initiated; the dependent lung was preferentially ventilated by 75-80% of the tidal volume, while the nondependent lung on the operative side was only ventilated by 20-25% of the tidal volume. DLV improved oxygenation and maintained adequate carbon dioxide elimination, with minimal inflation of the nondependent lung into the surgical field. DLV may be used to increase oxygenation whenever conventional OLV is associated with hypoxemia despite the use of 100% oxygen.

Adult↗