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Biomedical subjects

A Autret

Publications and source records attributed to A Autret.

At least 127 records · Page 7Linked to original sources
PubMed1980

[Influence of the cerebellum on voluntary ocular movements (author's transl)].

The influence of the cerebellum on voluntary ocular movements was assessed by an oculographic study of twelve patients with localized cerebellar lesions. The most frequent anomaly observed was dysmetry of movement. When asymmetric, if appeared as a homolateral hypometria of at least relative degree. The speed of the movements was normal in all cases. This study confirms the role played by the cerebellum as a "pre-programmer" and suggests that it controls rapid eye movements without the intervention of the long cerebellothalamocortical pathways.

Adolescent↗
PubMed1980

[Influence of the cerebellum on ocular statics and visual tracking movements (author's transl)].

It has long been admitted that the vestibular cerebellum plays a major role in the control of slow ocular movements. A study of 12 patients with localized lesions of the paleo- and neo-cerebellum has demonstrated that these recent structures also participate in the organization of visual tracking movements. These patients often have disturbances of ocular statics as well, and this can be the cause of slow movement disturbances. In most cases, however, ataxia of the tracking movement is not related to a statics disorder, but on the contrary, to disturbances of the movement itself. This suggest that the two cerebellar levels involved in ocular motility are related to two different types of movement strategies: vestibular cerebellar tracking having the very elementary function of maintaininf fixation within the overall picture of postural regulation: neo-cerebellar tracking, on the contrary, being already the beginning of voluntary motility.

Adolescent↗
PubMed1979

[Polygraphic study of nocturnal sleep in three degenerative diseases: ALS, oligo-ponto-cerebellar atrophy, and progressive supranuclear palsy].

A polygraphic study of nocturnal sleep was carried out on 12 patients suffering from amyotrophic lateral sclerosis (ALS), 6 patients suffering from olivio-ponto-cerebellare-atrophia (OPCA) and 9 patients suffering from the Steele-Richardson disease (SR). A disturbance of sleep--if it exists--always runs parallel with the course of the disease. No disturbances were registered in the group of patients suffering from ALS, in the OPCA group a specific disease of paradoxal sleep is observed. The sleep disturbances are more global in the group of patients suffering from the SR disease. A particular electrooculogram was taken from the patients from the awakening and from the paradoxal sleep. Respiratory difficulties were registered on certain patients of each of the three groups. These sleep disturbances, registered by the polygraph, were compared with those observed on patients presenting a cortical disease.

Adult↗
PubMed1979

A study on sleep in amyotrophic lateral sclerosis.

A polygraphic study of sleep has been performed on 12 patients with ALS and 12 normal controls. Neither the total duration of sleep, nor the proportion of different stages of sleep differed significantly between the patient and control groups. A variety of morphologic peculiarities were observed in certain patients: frequent and repetitive blinking movements during the waking state (under quiet, dark conditions); persistence of EMG activity during both PS and SWS; and an early appearance of marked slow delta wave activity at the beginning of sleep. We observed in patients increased PS latency, and longer and more frequent awakenings. Certain patients also showed both qualitative and quantitative abnormalities of respiratory rhythm. A longitudinal study was performed on one patient. Results are discussed in relation to the existing literature.

Aged↗
PubMed1979

[Bromide encephalopathies (author's transl)].

Bromide encephalopathies are frequently reported in Northern America and Great Britain. There is no characteristic clinical pattern, the neurological symptoms are multiple, this is readily explained by the diffusion of bromide ions to all regions in the central nervous system. An accurate history (bromide intake, followed by the slow onset of digestive and neuropsychiatric symptoms) as well as an apparent hyperchloremia are of the greatest aid in suggesting the diagnosis. The incidence of this type of intoxication is greater in women over 50. The association of a salt free diet to bromide therapy favors the onset of clinical symptoms because of the competition between bromide and chloride at the choroid plexus and at the renal tubule.

Brain Diseases↗
PubMed1978

Sleep respiratory arrhythmias in control subjects, narcoleptics and non-cataplectic hypersomniacs.

Normal subjects may present central-type apneas or periodic respiration during sleep (stages I and II and paradoxical sleep). The importance of these respiratory disorders increases with age. Hypersomniac patients can manifest either similar or more significant sleep respiratory disorders than normal subjects. The presence of cataplexy or obesity does not permit the prediction of the existence of respiratory arrhythmias or of their type. Sleep respiratory arrhythmias of central type are not likely to cause hypersomnia; however, an aggravating role may be played by obstructive apneas.

Adult↗
PubMed1978

[Action of Tiapride on wakefulness].

A "blind" study of the action of tiapride on vigilance was carried out in 3 healthy volunteers using polygraph recordings and psychometric tests. A total of 48 recordings were made in order to study the effects during initial treatment, long-term administration of a dose of 299 mg/day, and the rebound period, we also studied the effect of a single dose of 400 mg of tiapride. No quanlitative or quantitative changes in the polygraph recordings were noted. The psychological tests showed reduction of highest scroes and lowering of the overal efficiency level, but diminished attention during treatment was not observed.

Adult↗
PubMed1977

Effect of clonidine on sleep patterns in man.

Clonidine (300 microgram orally) increased in man the total duration of sleep and strikingly reduced the duration of REM sleep. Yohimbine (10 mg per os) did not alter the sleep patterns in man but antagonized the effects of clonidine. These results provide evidence that an alpha sympathomimetic mechanism could suppress REM sleep and increased the total duration of sleep.

Adult↗
PubMed1977

Clinical and polygraphic effects of d.1 5 HTP on narcolepsy-cataplexy.

d.1 5 hydroxy-trytophan (600 mg a day) or a placebo were administered during 4 weeks following a double blind cross over design to 11 narcoleptic-cataplectic patients. Daily number of cataplectic and narcoleptic attacks did not vary. The 36 hours polygraphic recordings performed at the end of each treatment exhibit: a trend toward a decrease of the duration of the day time sleep and a significant increase of the duration of the night sleep.

5-Hydroxytryptophan↗