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Biomedical subjects

A Agnoli

Publications and source records attributed to A Agnoli.

221 records · Page 13Linked to original sources

[The computerized electroencephalogram in evaluating the action of vasoactive and eumetabolic drugs in chronic cerebrovascular disorders].

In this work the authors estimated the effect, on cortical bioelectric activity, of two groups of drugs commonly used in the so-called chronic vascular cerebropathies. Through the computerized analysis of EEG the authors estimated vasoactive drugs (papaverine hydrochloride and xanthinol-nicotinate) and eumetabolic drugs (cytidin, uridin, cytidin + 1-glutamine association) in two groups of subjects (healthy volunteers and patients suffering from stabilized conditions of acute cerebrovascular insufficiency). As to vasoactive drugs, a different action of papaverine hydrochloride as compared to xanthinol-nicotinate was pointed out. Eumetabolic drugs showed an action of electroencephalographic activation statistically significant only if administered associated between them and with glutamine.

Adult↗

Mental impairment in Parkinson's disease. The role of anticholinergic drugs.

The trial has been carried out on 33 treated Parkinsonian patients and 14 healthy controls. A series of psychometric tests were employed in order to show a possible intellectual deterioration in Parkinsonian patients. Bender's test showed greater motor-perceptive deterioration in Parkinsonian patients respect to control, the Wechsler-Bellevue Intelligence Scale evidenced in patients significant deterioration of mnesic and psychomotor capacity. When considering drug treatments patients undergoing combined treatment or anti-cholinergics alone obtained worse results in all tests made whilst patients on L-Dopa alone obtained the best results.

Aged↗