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Results for “war of nerves”

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7 recordsLinked to original sources

Brinkmanship in intragenomic conflict.

When the Darwinian interests of genes in the genome collide, intragenomic conflicts evolve. Recent advances in social evolution predict that intragenomic conflicts shape diverse phenotypes. However, principles governing which side wins remain unresolved. Here, we use game theory to predict that power asymmetries arise from differences in appetite for risk between rival genes in 'wars of nerve'. We focus on 'genomic imprinting': differing expression between alleles inherited from mothers and fathers. Escalating conflict is commonly believed to risk damaging the whole organism. We show that genes can exploit risk strategically: genes prepared to take greater risks with the body's vulnerability to disorders and mortality gain coercive advantages, deterring countermoves. Kin selection generates differences in appetite for risk: for instance, if harm to the body frees resources for maternal siblings, genes from mothers have less to lose from gambling with the current body than do genes from fathers. Seemingly maladaptive developmental risks can be adaptively useful for higher-nerve genes, much as political states manipulate risk to coerce rivals. Our results suggest a determinant of power alongside the 'loudest voice prevails' principle, and call for empirical investigation of the extent and means by which risks of imprinting-related disorders are amplified by intragenomic brinkmanship.

Genomic Imprinting

[Effects of the nervous system on the kidney. Part I. Review of the literature].

The authors review the literature on the effects of the nervous system on the kidney in 3 stages: 1) Historical stage when the role of the renal nerve supply was overetimated by Claude Bernard. 2) Intermediate stage between the two wars with a clinical description of uremic encephalits or acute delirium. From the experimental point of view was demonstrated the inessential character of the nerve supply for the survival of the kidney. 3) Modern stage: from the clinical point of view one may distinguish functional nephropathies including those of nervous origin. The latter are due to metabolic or vascular mechanisms which are intricated to various degrees. Problems of regulation are raised in man by certain findings.

Brain Diseases

[The influence of TNS (transcutaneous nerve stimulation) on placental flow (author's transl)].

A report about 12. gravid patients with a diminished uteroplacental flow is given. To increase their placental perfusion a transcutaneus lumbo-sacral electric nerve stimulation was performed. In all 12 cases a distinet increase war measured by the method of radioisotope placenta-perfusion. The mean values showed a high significant difference (p less than 0,001). The reasons for this results and the possibilities of this findings for the therapy of funcitonal placental insufficiency are discussed.

Electric Stimulation

Acupuncture analgesia and anesthesia.

After the war of liberation, Mao Tse Tung encouraged an integration of Western and traditional Chinese medicine. Several schools of therapeutic acupuncture have defined different points of puncture, originally assumed to be on an empiric basis but now rationalized as areas where nerve endings congregate. Results of therapeutic acupuncture in China cannog be evaluated because of inadequate record keeping. At the University of Washington Pain Clinic, immediate results (two to three days) are good but never lasting, nor do they decrease concomitant medication. For anesthesia, acupuncture acts to produce only hypalgesia in most patients, although some experience total analgesia. Patient selection and mental preparation are careful. Hence, the method is used in much less than 10% of the operations in China, and in these the analgesia is satisfactory by Western standards in only approximately 30%. Concepts as to the mode of action of acupuncture analgesia range from an attitudinal change towards sensory input to the release of a neurohumoral analgesic substances.

Acupuncture Therapy

Extracranial vertebral aneurysm with neurofibromatosis.

With neurofibromatosis neuromas of the cranial and cervical nerves are common findings and meningiomas and ependymonas appear more often than in the average population. Vascular manifestations of the disease are also commonly known in the renal and gastrointestinal vessels but rarely in the large cerebral arteries. The case of a 50 year old man with neurofibromatosis and a vertebral aneurysm is reported. The plain X-ray of the cervical spine and the Pantopaque myelogram were compatible with a cervical neuroma and the patient was operated but a large aneurysm of the vertebral artery was found. The operation was discontinued and vertebral angiography was performed revealing a large saccular aneurysm which war excised. This aneurysm is most probably a manifestation of vascular disease with neurofibromatosis.

Aneurysm