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A Decade of Achievements and Future Directions in Global Antimicrobial Resistance Surveillance System in Korea (Kor-GLASS).

OBJECTIVES: To comprehensively evaluate the 10-year operational outcomes (2016-2025) Global Antimicrobial Resistance Surveillance System in Korea (Kor-GLASS), assess its public health significance for national stewardship and global surveillance, and propose strategies for future development. METHODS: The study described the operational framework of Kor-GLASS, including its strain collection, analysis, and quality control systems, based on surveillance data. It analyzed resistance trends among key bloodstream pathogen isolates collected from 2016 to 2024 and evaluated major achievements, including alignment with the World Health Organization (WHO)'s Global Antimicrobial Resistance Surveillance System (GLASS), integration with the Emerging Antimicrobial Resistance Reporting (EAR) system, and activities as a WHO Collaborating Centre. RESULTS: Kor-GLASS operates on a foundation of standardized, isolate-based surveillance supported by an independent quality management system that complies with WHO GLASS standards. In alignment with the strategic direction of WHO GLASS, the surveillance scope has progressively expanded in terms of catchment areas, target pathogens, specimen types, and antimicrobial panels. From 2016 to 2024, a total of 116,955 clinical isolates were collected and analyzed through the network of collection and analysis centers. This has enabled the continuous generation of nationally representative antimicrobial resistance (AMR) data from general hospitals. The accumulated surveillance data provide fundamental evidence for tracking long-term resistance trends and elucidating the molecular epidemiological characteristics of key pathogens. These outcomes are disseminated through the publication of the "National Antimicrobial Resistance Surveillance Annual Report" and data submissions to WHO GLASS and GLASS-EAR, thereby supporting both national and global AMR surveillance efforts. Furthermore, Kor-GLASS has strengthened international surveillance and One Health collaboration capacities through its designation and redesignation as a WHO Collaborating Centre for AMR Surveillance. CONCLUSIONS: Over the past decade, Kor-GLASS has served as the cornerstone of national antimicrobial resistance surveillance, providing evidence to inform policy and supporting global surveillance systems. Moving forward, Kor-GLASS is expected to evolve into a pivotal national AMR surveillance system through the introduction of whole-genome sequencing and stronger integration with national antimicrobial consumption surveillance.

Anti-bacterial agents

Exploring the use of death certificates as a component of an occupational health surveillance system.

An effort has been made to explore a case-finding surveillance system for occupationally-related disease using death records. A sentinel health event, here lung cancer in young males, was selected to seek unusual associations with occupations as listed on the death records. Fishermen appeared to be over-represented and population studies cited suggest lung cancer in this occupation deserves further exploration. Further efforts of this type could test the usefulness of an occupational health surveillance system based on the death certificate.

Adult

Design philosophy of air quality surveillance systems.

This paper discusses the design philosophy of the air quality surveillance systems which Kennecott is installing in the vicinity of its copper smelters in Arizona, Nevada, New Mexico, and Utah. These monitoring systems are part of supplementary control systems (SCS) that are utilized to ensure that short-term ambient air quality standards are met. These systems utilize minicomputers as remote terminals. The interface between a terminal and the primary sensors is via specially designed input/output circuitry. The system is controlled by a centralized host minicomputer, which is connected to each of the remote stations via a telephone line communication network. Real time data is displayed on cathode ray tubes located at strategic locations in the plants. This paper will discuss the system design philosophy from both a hardware and software point of view. The actual experience in design, development, and installation of the system will also be discussed.

Air Pollutants

Planning a food and nutrition surveillance system: the example of Honduras.

A description of the preliminary steps in establishing a food and nutrition surveillance system in a country of Central America is presented in outline. The system will provide the basis for policy formulation, program planning, and evaluation. It is organized on the basis of the participation and resources of seven national agencies and will operate at the local, regional, and central level.

Food Services

Hospital emergency department surveillance system: a data base for patient care, management, research and teaching.

The Johns Hopkins Health Services Research and Development Center and Emergency Department have developed a processing and feedback mechanism to provide a data base for management planning, allocating available resources, research strategies to evaluate the quality of care and teaching programs to train physicians in emergency medicine. A 10% sample of all emergency department visits is randomly selected each day, and data collected on patient age, sex, race, marital status, mode of arrival, method of payment, census tract of residence, complaint, diagnosis, disposition, date of visit, and times of entry and departure. In addition, process data on nursing care are collected. A sub-sample is selected for telephone or household follow-up aimed at gathering outcome data as part of the surveillance study. Turnaround time from the subject's emergency department visit to provider's feedback is one month. Thus, an ongoing, current description of usage is available. Retrieval of data for longer time periods provides valuable information on daily, monthly and seasonal usage patterns.

Abstracting and Indexing

History and status of the Cancer Surveillance System of Western Washington.

A cancer registry for a population of over 2 million people was established in 1973. Although the population is predominantly white, the presence of people of Oriental stock provides a potential for migrant studies and international comparisons. Over 7,900 resident cancer cases are detected annually, and a good system for evaluating completeness of reporting and quality of collected data has been devised. To utilize the resources that the registry represents, we have a competent staff of epidemiologists and biostatisticians with academic appointments at the University of Washington and interests in cancer etiology, evaluation of care, and teaching.

Adolescent

Followup of implanted pacemakers: an evaluation of surveillance methods.

A waveform analysis clinic augmented by telephone transmission of pacemaker interval in the late stages of pacemaker life will yield a considerable amount of information and will permit elective replacement of pacemakers in about 90 per cent of cases. The clinic has an advantage over other surveillance systems in the accuracy of the diagnosis, the identification of abnormalities that do not require pacemaker replacement, and the multiple benefits of a direct doctor-patient relationship. No system of surveillance can be recommended over all others in all circumstances. It is sufficient here to indicate the merits of each system and to allow the various centers to develop according to their own particular needs and desires. There is no objection to telephone monitoring alone as long as one realizes that only about 80 per cent of the problems can be detected and that there will be an irreducible percentage of false negative and false positive diagnoses. The danger of errors of this type is not great, but it does exist and should be avoided if possible. Other methods of pacemaker followup, such as simple examination and an electrocardiogram in a doctor's office or changing the pacemaker on the basis of the manufacturer's prediction, are relatively unsatisfactory. It should be stressed that pacemaker surveillance of some type is essential to satisfactory patient care because it provides for maximum utilization of the pacemaker, for replacement only if and when necessary, for detection of 90 per cent of pacemaker problems, and for protection of the patient against unexpected pacemaker failure.

Costs and Cost Analysis