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Results for “reticular cells”

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At least 19 recordsLinked to original sources
PubMed1976

[Appearance of phosphatase reticular cells in the spleen parenchyme of normal and tumor-bearing mice].

The splenic mouse parenchyma presents 3 reticular cells types revealed by histo-enzymatic technics: the phagocytic cells show a strong phosphatasic acid activity, the endothelial cells possess a phosphatasic alcalin or adenosine-triphosphatasic reaction, the perithelial cells are 5' nucleotidasic. These different cells are distributed by forming specific topographic structures in the splenic tissue. The phosphatasic alcalin reticular cells seem to be, with their distribution, characteristic elements of mouse spleen. Indeed the modifications in tumoral animal interest chiefly this cell category. In this case, the reticular cells form a deep and large membrane between marginal zone and perivascular lymphoid sheath of the white pulp. These different reticular cells probably react for the defense system of the animal.

Acid Phosphatase↗
PubMed1977

Fine structure of the reticular cells in the rat spleen, with special reference to their fibro-muscular features.

Reticular cells in the rat spleen were studied with the electron microscope. Besides well developed cisterns of the granular endoplasmic reticulum and the Golgi complex like in fibroblasts, the reticular cells contain small bundles of microfilaments, dense bodies and hemidesmosomes as in the smooth muscle cell. Based on these cytological characteristics, it is suggested that the reticular cells are fibro-muscular in nature, and they may play roles in fibrogenesis as well as in regulation of the blood flow by their contraction in the splenic reticular tissue.

Animals↗
PubMed1975

[The effect of cortisone on lympho-reticular cells with specific enzyme activity of the white pulp of rat spleen].

By its destructive effect on the small lymphocyte, cortisone was used to separate the T-lymphocyte from other cells which might be found in the same areas. A reticular cell showing a predominant 5' nucleotidasic activity distinct from that of the phosphatasic acid appeared to be a component of the thymus-dependent areas in the splenic white pulp of Rat. Specific correlations seem to exist between this reticular cell and T-lymphocytes. This histoenzymatic feature involves the reticular cell in the process of maturation of the small lymphocyte.

Animals↗
PubMed1976

Reticular cell hyperplasia and amyloidosis in a line of mice with low leukocyte counts.

Two pathologic conditions, reticular cell hyperplasia and amyloidosis, were studied in a strain of mice selectively bred for low leukocyte counts (LLC). At the age of 3 to 6 months, 70% of the mice developed reticular cell hyperplasia in the inguinea lymph nodes, and at 11 to 18 months, about 100% of them developed amyloidosis in the spleen and in the kidney, liver, and adrenal glands. Immunofluorescence was revealed in the glomeruli, interstitium of the tubules, and the amyloid skeleton of the papilla when the kidney sections were incubated with fluorescein-labeled antimouse immunoglobulins. Both intracellular and extracellular amyloid fibrils were found in the liver, spleen, and kidney sections by electron microscopy. Distended rough endoplasmic reticulum (RER) cisternae and hypertrophy of RER with or without the simultaneous presence of amyloid fibrils in the reticular cells of the spleen and Kupffer cells of the liver were observed. In this light, we believe that the pathologic conditions are manifestations of immunologic events that are characteristic of the LLC mice with immune deficiency or abnormality in the immune system. We conclude that the origin of amyloid protein is at the RER. We discuss processes of amyloid fibril formation and some genetic aspects of amyloid development.

Adrenal Glands↗
PubMed1978

[Release of the nucleoli and karyoplasm into the cytoplasm of reticular cells in lymph node cultures].

Successive stages of the process characterizing the release of the nucleoli and part of the nuclei contents into the reticular cell cytoplasm were recorded in the primary cultures of the lymph nodes of albino mice with transplantable leukemia. Comparison of the results obtained with the autoradiographic data pointing to the high proliferative and metabolic activity of the reticular cells permits a suggestion that the recorded phenomenon reflected the secretory function of the stroma cells of the hemopoietic organs at the morphological level.

Animals↗
PubMed1978

[Formation of heterosymplasts in human reticular cell cultures].

The cell fusion has been studied in human reticular cell cultures J-96 and J-41 treated with the Sendai virus or with polyethylene glycol 1000 and 6000. The J-96 cells have a high alkaline phosphatase activity, in J-41 cells the enzyme is not detectable. No heterogenous alkaline phosphatase activity was seen in the protoplasm of symplasts 18 hours after virus cell fusion. It has been shown with polyethylene glycol treatment that during the fusion of cells J-96 and J-41 the enzyme activity was spreading over the symplast protoplasm.

Alkaline Phosphatase↗
PubMed1976

[Species characteristics connected with the distribution of reticular cells with predominant enzymatic activity of the white pulp of the spleen of various rodents].

The histo-enzymatic comparative study of the reticular cells of some rodents' spleens (Rat, Guinea-Pig, Rabbit), shows many differences between these species. Three cell types can be seen; the phosphatasic type is phagocytic and derives from the M.P.S. system, the 5'nucleotidasic is not a phagocytic cell and probably comes from the vascular perithelium, the ATPasic cell is, perhaps, an endothelial cell. These different cells are not equaly distributed in the splenic parenchyma of all animals but one type can be lacking.

Acid Phosphatase↗
PubMed1975

[Comparison of topographical locations of reticular cells with 5'-nucleotidase activity in spleen white pulp and lymph nodes in man and rat].

The cells connections occuring in thymus-dependent areas of the splenic white pulp of rat between 5'nucleotidasic reticular cells and small lymphocytes allowed to research this same associated cells in the rat lymph node and the human splenic white pulp and lymph node. The locations of the thymus- dependent areas seem different in man and rat.

Animals↗
PubMed1976

[Karyometry of thymic reticular cells in the rat. Effect of hydrocortisone and adrenalectomy].

A new process in taxinomic analysis clearly confirmed the presence of three different types of cells (epithelial, hypertrophic and mesenchymal) in the reticular zone of the thymus. The injection of hydrocortisol as well as adrenalectomy induced specific changes in nuclear surfaces of three cell types, while hydrocortisol tented to increase the surface of epithelial and mesenchymal cells, adrenalectomy reduced it, while a modification was seen in the percentages relative of the cell types. In adrenalectomized animals, the effect result was counteracted by injections of hydrocortisol.

Adrenalectomy↗
PubMed1976

An ultrastructural analysis of lympho-reticular cell interactions in primary cultures of human non-lymphoid neoplasms and lymphomas.

The morphology and interactions of lymphoreticular cells in cultures of human tumour tissue was studied by transmission and surface scanning electron microscopy. Macrophages are very common in non-lymphoid neoplasms and vary considerably in shape and surface morphology, with features of mature stimulated cells. Lymphocytes adhere to macrophages more often than to tumour cells. Close contact between macrophages and tumour cells also occurs, but there is no evidence that the infiltrating macrophages or lymphocytes have an overt cytotoxic effect under these cultural conditions. A variety of interactions are seen in cultures of Hodgkin's lymphoma, lymphosarcoma and reticulum cell sarcoma. The only cultural characteristics that may be specific for lymphoma tissue are large intravacuolar collections of lymphocytes within macrophages or giant cells and the rare close spatial relationship between lymphocytes and degenerate macrophages, the latter particularly in Hodgkin's lymphoma. These observations demonstrate the disturbed cellular interrelationships that exist in lymphoma tissue.

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