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[Current data on atmospheric pollutions].

Atmospheric pollutions (AP) are very important for human health and ecological equilibrium. They may be natural or anthropogenic and in this later case they can appear outdoor or indoor. Urban air pollution is the most known form of AP. Its main sources are industries, individual and collective heating and now mainly automobile traffic in most cities. Classical AP indicators are SO2, particles, NOx, CO and Pb measured in networks. Important factors of AP are amounts of pollutants emitted and local climatic and meteorological characteristics. Health effects of AP peaks and of AP background levels are not well known. But generally, mean AP levels of SO2 and particles decreased in the last years in most towns as the consequence of collective actions on the three main sources of AP and on fuels, emission and immission levels; but more is wanted about motor-cars. Progress are necessary for limitation of three major ecological risks: "acid-rain" (SO2 and NOx derivatives, ozone,...) which participates in lake and forest attacks; "green house" effects whose air CO2 concentration increase is the main responsible, and stratospheric ozone depletion mainly due to freons (CFC); the consequences of these two last phenomena are not well known but ecological and health risk exist. Besides, indoor air pollution (IAP) is very important because we live more than 20 h a day indoor. IAP may be occupational (a lot of chemical or biological agents) or not. In the later case air pollutants are very various: CO, NOx and particles from heating or cooking, formaldehyde from wood glue, plywood or urea-formol foams, radon and derivatives in some granitic countries, odd jobs products, cosmetics, aero-allergens of chemical or biological origins, microbes,... Environmental tobacco smoke (ETS) is also an important pollutant complex. Risks of IAP are real or potential: acute risk is obvious for CO, aero-allergens, formaldehyde, NOx,...); irritations are produced by ETS, formaldehyde, solvants,...; long term or potential risks are of concern for asbest, radon,... A complex and bad known pathology is described in a lot of modern buildings as the "Sick Building Syndrom". Indoor air quality is very dependant of the quality of ventilation and possible air treatment. It may be considered in all urban epidemiological studies about air pollution.

Air Pollution↗

Immunoglobulins and some serum proteins in children with altered resistance coming from areas with variously polluted atmosphere.

In four areas with different types of atmospheric pollution 534 children of school age were examined for serum immunoglobulins (IgG, IgA, IgM and IgE), saliva IgA (sIgA), lysozymes (LYS) and acute phase reactants (alfa-l-antitrypsin - A1AT, alfa-2-macroglobulin -A2M, ceruloplasmin -CPL, transferrin - TRF). The children were divided into two groups: those with altered resistance (AR) comprising allergoses of all types and recurrent or persistent infections and those without the above health problems, i.e. healthy (H). There were more children with AR in areas with higher atmospheric pollution than in control areas. The frequency of AR was higher among boys than among girls. In the control area BN, a number of parameters in the AR group differed significantly from those in the H group. In areas with substantial atmospheric pollution these differences were generally less pronounced. Significant differences were found between the control and polluted areas in many indicators. In the area KO characterized by an intermediate degree of industrial pollution the means of the tested parameters were habitually elevated, whereas in the heavily polluted areas they were decreased. The most sensitive tests for evaluating differences between the areas were the levels of A1AT, LYS, and IgE, while the variations of sIgA, sLYS and CPL were less pronounced.

Air Pollution↗

Activation of polycyclic aromatic hydrocarbons to mutagens by singlet oxygen: an enhancing effect of atmospheric pollutants?

Chrysene and 3-methylcholanthrene are transformed to direct-acting mutagens by photodynamically generated singlet oxygen. In view of the presence of this species of oxygen in the polluted atmosphere, the possible conversion of environmental polycyclic aromatic hydrocarbons to mutagens and to potential direct-acting ('ultimate') carcinogens deserves consideration.

Carcinogens, Environmental↗

Industrial atmospheric pollution, historical land use patterns and mortality.

BACKGROUND: The measurement of atmospheric pollution for epidemiological studies is problematic. This study presents a new proxy measure of atmospheric pollution of industrial origin and uses it to determine, at electoral ward level, the relationship between atmospheric pollution and all-cause mortality. METHODS: All-cause Standardized Mortality Ratios (SMR), all ages, and for persons under 65 years for the period 1984-1988, proportions of land in each ward utilized by industrial works (the proxy for atmospheric pollution) and levels of socioeconomic deprivation of the ward residents were compared in 104 electoral wards. RESULTS: The all-age SMR in the 22 wards containing the largest proportions of industrial land (113) was 9.7 per cent higher than the SMR (103) in the 60 wards with no industrial land. The under 65 years SMR in the 22 highly industrialized wards (120) was 22.4 per cent higher than the SMR (98) in the wards with no industrial land. After matching the levels of deprivation, the all-age SMR in the 15 wards containing over 10 per cent industrial land (116) was significantly higher than the SMR in 15 wards containing no industrial land (108); corresponding figures for the under 65 years SMR were 135 and 118. CONCLUSIONS: A greater proportion of industrial land in a ward is associated with a higher mortality of the ward residents, even after controlling for the level of socio-economic deprivation of the residents. The association between deprivation and mortality is stronger than the association between atmospheric pollution and mortality. There is an urgent need for better measures of atmospheric pollution which are usable in epidemiological studies.

Adolescent↗

Plants as bioassay systems for monitoring atmospheric pollutants.

Plant species act as natural bioindicators of atmospheric pollutants. Plants can be used as bioassay systems for monitoring atmospheric pollutants. Plant injury symptoms, altered growth and reproductive pattern, changes in yield and/or productivity, and changes in species distribution can be used singly or in combination as monitoring devices. The results must be accepted as semiquantitative, but within that constraint, air quality can be sufficiently well defined to enable the setting of air quality standards. Genetic variability of higher plant species has yielded cultivars which display a range of tolerance to gaseous and particulate atmospheric pollutants. Asexual propagation of these cultivars provides pollutant-sensitive and pollutant-tolerant plant material which can be grown on selected sites for observation. Gymnosperm and Angiosperm species as well as species of lichens and mosses have been used to establish field monitoring networks in Europe, Canada, and the United States. White pine, shade tobacco, mosses, and lichens have proven particularly useful as bioassay tools. Pollen from pollutant-sensitive and pollutant-tolerant plant cultivars has also been used as a sensitive laboratory bioassay tool for studying air quality. Epiphytic mosses are particularly efficient as monitors of particulate pollutants, especially heavy metals, some of which may act as chemical mutagens. The cost, complexity, and lack of reliability of instrumented systems for air quality monitoring make imperative the need to develop successful plant bioassay systems for monitoring air quality.

Air Pollutants↗

[Simulation of polluted atmospheres for animal experimentation: toxic gases].

A process for the generation of standardized polluted atmospheres usable for animal exposure is described. It is based on the diffusion of compressed gases across a silicone membrane. This device has been tested with four gases of particular importance in the field of atmospheric pollution (sulfur dioxide, nitrogen oxide, carbon monoxide and ammoniac).

Air Pollutants↗

[Atmospheric pollution. Biological aspects and role of meteorologic factors in the distribution of respiratory hazards in the environment and relative prognostic and preventive measures].

The biometeorological factors underlying atmospheric pollution are discussed, together with its biological effects and its direct and indirect damage to human health. Damage is particularly likely when particularly adverse ambient and climatological conditions result in a massive and persistent concentration of contaminants in the ambient air. In this case, since the highly biologically interesting phenomenon of physicochemical reaction between pollutants and atmospheric components prevails over that of the dilution and dispersion of such contaminants, nature's major processes of removal and self-purification may be rendered nugatory and insufficiently prompt. The effects of atmospheric pollution, primarily with respect to urban background pollution, on human health make their appearance in the respiratory system, where there is a continuous relation between man and his environment throughout his life, in the form of immediate or short, medium and long-term damage. The desirability of preparing a meteorological map showing the distribution of the risk of atmospheric pollution is discussed. For this purpose, use could be made of meteorological data, and the hi-tech observations now made possible, inter alia, by the employment of satellites and aerospace data. A map of this kind would give more precise information concerning the part played by the weather in distributing the risk of respiratory damage caused by environmental pollution. It would also provide the knowledge required for the purpose of prediction and prevention in an organised struggle against such pollution. This would be of great social significance and value. Its practical applications could be enormous consequence to humanity.

Air Pollutants↗

[Morphological features of the nasal mucosa in healthy children exposed to different concentrations of atmospheric pollution].

OBJECTIVE: During the last decades the impact of pollution in big cities on the upper respiratory tract of children has become an issue of interest. The purpose of the present study was to determine if exposure of healthy children to different concentrations of atmospheric pollution alters morphologically the nasal respiratory epithelium. MATERIAL AND METHODS: In this randomised, prospective, open clinical trial we included 71 healthy children matched for age and sex and divided them into 3 groups: Group I, 31 children from Mexico City. Group II, 21 children from Tula, Hidalgo a moderate polluted area, and Group III, 19 children from Contepec, Michoacán, a rural non-polluted area. We took a nasal biopsy from the lower turbinate and performed nasal cytology in all children. The samples were examined twice by a pathologist with a double-blind technique. Ozone measurements were taken during 1992. RESULTS: Nasal symptoms (nasal obstruction, pruritus and dryness) were present in 96.8%, 71.4% and 52.6% of patients in groups I, II and III respectively (p = 0.001). We also found bilateral hypertrophy turbinates in 100% of children in group I versus 81% and 73% in groups II and III (p = 0.009). Citologic examination disclosed no significant differences among the study groups, although p values were 0.06 respecting inflammation and abnormal goblet cells when we compared group I versus group II and III. Respecting histological examination we found significant differences when comparing group I versus II and III in squamous metaplasia (p = 0.02) and pseudoepitheliomatous hyperplasia (p = 0.003), with not significant differences among keratinization (p = 0.06) and dysplasia (p = 0.06). CONCLUSIONS: The results of this study indicate that exposure to a polluted atmosphere is followed by severe changes in the histology and cytology of the nasal mucosa in healthy children, with these changes being more frequent and severe in the more polluted areas. These findings implicate that we must put more attention on the long term effects of atmospheric pollution in order to establish stronger control measures.

Adolescent↗

[Long-distance transportation of atmospheric pollutants and its effects on ecosystems].

It was known, as far back as the nineteenth century, that rain water from industrial areas was more acid than that from rural areas. The potential risks for life in general were discussed, but no further attention was paid to the issue. At the end of the twentieth century, the ecosystems of Europe, Canada and the United States have been severely damaged by pollutants borne by atmospheric winds to places distant from their origin. The main effects of these atmospheric pollutants are due to sulfur and nitrogen oxide dilution and to photochemical reactions. International organizations have been formed and agreements pronounced and ratified by many countries for a universal study on the pollution process, on the transport of pollutants--mostly sulfur, nitrogen and ozone--and on how to collaborate in order to reduce emissions in the respective countries of origin for the worldwide profit.

Air Pollutants↗

Impact of urban atmospheric pollution on coronary disease.

Recent epidemiological findings have suggested that urban atmospheric pollution may have adverse effects on the cardiovascular system as well as on the respiratory system. We carried out an exhaustive search of published studies investigating links between coronary heart disease and urban atmospheric pollution. The review was conducted on cited articles published between 1994 and 2005 and whose main objective was to measure the risk of ischaemic heart diseases related to urban pollution. Of the 236 references identified, 46 epidemiological studies were selected for analysis on the basis of pre-defined criteria. The studies were analysed according to short-term effects (time series and case-crossover designs) and long-term effects (case-control and cohort studies). A link between coronary heart disease and at least one of the pollutants studied (PM10, O3, NOx, CO, SO2) emerged in 40 publications. Particulate matter, nitrogen oxides, and carbon monoxide were the pollutants most often linked with coronary heart disease. The association was inconstant for O3. Although the mean mortality or morbidity risk related to urban atmospheric pollution is low compared with that associated with other better-known risk factors, its impact on health is nevertheless major because of the large number of people who are exposed. This exhaustive review supports the possibility that urban pollution is indeed an environmental cardiovascular risk factor and should be considered as such by the cardiologists.

Air Pollution↗

Interpretation of atmospheric pollution phenomena in relationship with the vertical atmospheric remixing by means of natural radioactivity measurements (radon) of particulate matter.

In this paper the results of seasonal monitoring campaign for primary (benzene and carbon monoxide) and secondary (nitrogen dioxide and ozone) pollutants and for the natural radioactivity of the particulate matter in the urban area of Rome, are reported to investigate acute atmospheric pollution episodes. Comparing the daily concentration trends of primary and secondary pollutants with those of the natural radioactivity, considered as index of the vertical diffusion in the low boundary layer, it has been evidenced that the acute pollution episodes in Rome occur in the winter period for the high atmospheric stability (primary pollution) and in the summer period for the strong diurnal atmospheric remixing (secondary pollution).

Air Movements↗

[Structuro-functional changes in the placenta as a result of exposure to atmospheric pollutants].

Under the influence of atmospheric pollutions certain structural-functional changes take place in placenta: terminal villi per stipulated square unite, villi with desquamated epithelium, with dilated vessels, with deposition of fibrinoid masses, with plasmodial buds increase in number; section area occupied by epithelial layer decreases; RNA concentration and histoenzymatic activity change in the latter.

Adolescent↗

Concentration of atmospheric pollutants in the gaseous emissions of medical waste incinerators.

The purpose of this paper is to quantify the production of medical waste from a general hospital and to evaluate the atmospheric pollutant concentrations in gaseous emissions associated with its incineration. A 3.8 kg (bed.day)-1 production of medical waste was estimated for 1998; its incineration is related with an ash production of 0.3-0.4 kg (bed.day)-1. The concentrations of atmospheric pollutants were estimated using emission factors, comparing the effluents with and without control of atmospheric pollutants. The calculated concentrations were compared with the emission limits established by Portuguese legislation. The results indicate that, if there is no control of atmospheric pollutants, their concentrations exceed the established limits. This is observed even if correct operation and maintenance procedures are used. The emission concentrations of dioxins are higher than the Portuguese emission limit, which is particularly worrying due to the high toxicity of some of these compounds. Generally, it is possible to reduce pollutant concentrations if appropriate control equipment is used. The conclusions obtained clearly justify the great concern regarding air pollution associated with medical waste incinerators currently operating in Portugal.

Air Pollutants, Occupational↗

[Changes in the spatial structure of the destruction process under the conditions of atmospheric pollution of forest ecosystems].

Contamination of the southern taiga forests (Middle Urals) by discharges from cooper smelters (heavy metals combined with SO2) not only decreases the mean rate of decomposition of pure cellulose, but also radically changes the spatial structure of the destruction process. Heterogeneity of distribution of the destruction rate is sharply increased near the source of discharge due to differentiation of the space into microregions with high and low destruction rates. The characteristic size of spatial heterogeneity amounts to several tens of centimeters and the distribution of microregions with a high rate is accidental within several tens of meters. A hypothesis has been put forward that the described changes in the spatial structure of the destruction process are related, above all, to disturbed colonization of the substrate by soil myxomycetes.

Air Pollutants↗

Influence of meteorological parameters on particulates and atmospheric pollutants at Taichung harbor sampling site.

Atmospheric aerosol particles and metallic concentrations, ionic species were monitored at the Experimental harbor of Taichung sampling site in this study. This work attempted to characterize metallic elements and ionic species associated with meteorological conditions variation on atmospheric particulate matter in TSP, PM2.5, PM2.5-10. The concentration distribution trend between TSP, PM2.5, PM2.5-10 particle concentration at the TH (Taichung harbor) sampling site were also displayed in this study. Besides, the meteorological conditions variation of metallic elements (Fe, Mg, Cr, Cu, Zn, Mn and Pb) and ions species (Cl(-), NO3 (-), SO4 (2-), NH4+, Mg2+, Ca2+ and Na+) concentrations attached with those particulate were also analyzed in this study. On non-parametric (Spearman) correlation analysis, the results indicated that the meteorological conditions have high correlation at largest particulate concentrations for TSP at TH sampling site in this study. In addition, the temperature and relative humidity of meteorological conditions that played a key role to affect particulate matter (PM) and have higher correlations then other meteorological conditions such as wind speed and atmospheric pressure. The parameter temperature and relative humidity also have high correlations with atmospheric pollutants compared with those of the other meteorological variables (wind speed, atmospheric pressure and prevalent wind direction). In addition, relative statistical equations between pollutants and meteorological variables were also characterized in this study.

Air Pollutants↗

Urban atmospheric pollution: personal exposure versus fixed monitoring station measurements.

We initiated the PETER (pedestrian environmental traffic pollutant exposure research) project to investigate pedestrians' exposure to traffic related atmospheric pollutants, based on data obtained with the collaboration of selected categories of pedestrian urban workers. We investigated relations between roadside personal exposure levels of volatile aromatic hydrocarbons (including benzene) and particulate matter <10 microm (PM10) among traffic police (n = 126) and parking wardens (n = 50) working in downtown Bologna, Italy. Data were collected from workshifts throughout four 1-week periods in different seasons of 2000-2001. For benzene and PM10, comparisons were made with measurements by fixed monitoring stations, and influence of localized traffic intensity and meteorological parameters was examined. Roadside personal exposure to benzene correlated more strongly with other volatile aromatic hydrocarbons (toluene, xylenes and ethylbenzene) than with PM10. Benzene and PM10 personal exposure levels were higher than fixed monitoring station values (both p<0.0001). At multivariate analysis, benzene and PM10 data from fixed monitoring stations both correlated with meteorological variables, and were also influenced by localized traffic intensity. Plausibly because of the downtown canyon-like streets, weather conditions (during a period of drought) only marginally affected benzene personal exposure, and moderately affected PM10 personal exposure. These findings reinforce the concept that urban atmospheric pollution data from fixed air monitoring stations cannot automatically be taken as indications of roadside exposures.

Air Pollution↗

Comparative biochemical and morphological investigation of the liver of experimental animals in the process of hepatotropic effect of atmospheric pollution (on the model of carbon tetrachloride).

The authors effected a comparative examination of morphologic and biochemical investigation of structural and enzymic reactions of the rat liver during different periods of permanent inhalation influence of carbon tetrachloride. Three stages of morphologico-biochemical parllels in the development of hepatotropic effect characterized by certain regularities in the enzymic desorganization of lysosyme, mitochondrias and cytasol by derangement of the exchange of biopolymers containing carbohydrate (of glycoproteids, glycosaminoglycans) and DNK-synthetizing function in liver in comparison with control animals were revealed. Mechanisms of the hepatotropic effect and hygienic importance of structural function changes of hepatocytes due to action of factors polluting the atmosphere are appreciated.

Air Pollutants↗