Search PubMedSearch

SEARCH · Search PubMed

Results for “Zimbabwe”

Search indexed PubMed citations on genomics, clinical trials, systematic reviews and public health. Explore titles, authors and supplied subject terms, then open the PubMed record.

Quote a phrase for an exact phrase match. Source license links do not imply unrestricted reuse.

At least 19 recordsLinked to original sources

Zimbabwe's success story in education and health: will it weather economic structural adjustment?

The beginning of the 1980s saw the birth of Zimbabwe as a result of a protracted liberation war. It coincided with global interest in primary health care, the concept of universal primary school education and, unfortunately, moves towards economic stabilization and structural adjustment programmes. Economic structural adjustment was adopted by several sub Saharan African countries with dire consequences for the poor and vulnerable. Zimbabwe's commitment to social justice and to equitable distribution of resources demonstrated a practical move away from the culture of rhetoric so characteristic of many governments and non-governmental organisations and agencies. This commitment has been translated into impressive improvements in health and education. Current evidence shows that education has had a positive impact on health and related areas like contraceptive use, child mortality and the nutrition status of children. Conversely nutrition and health conditions among school children are important determinants of educational outcomes. Hitherto Zimbabwe's economy has been sufficiently strong to avoid excessive dependence on the International Monetary Fund, the World Bank and other foreign financial institutions. Unfortunately, however, the current economic recession together with economic structural adjustment programmes are beginning to have a negative impact on health and education. Will true synergism between health and education weather these structural problems? It seems that the people and government of Zimbabwe have the capacity and resolve to weather such a storm.

Economics

Psychometric properties of the revised UCLA Loneliness Scale and two short-form measures of loneliness in Zimbabwe.

The cross-cultural reliability in Zimbabwe of the Revised University of California at Los Angeles (UCLA) Loneliness Scale and two short forms of the Revised UCLA Loneliness Scale were investigated. Subjects comprised a sample of 1,354 adolescents and another sample of 754 adults. The reliability of the Revised UCLA Loneliness Scale was acceptable. The internal consistency of an eight-item short form of the Revised UCLA Loneliness Scale was adequate, but the reliability of a four-item short form was low. Factor analysis of the Revised UCLA Loneliness Scale, which yielded two factors similar to those reported in North America by Zakahi and Duran (1982) supported the construct validity of the Revised UCLA Loneliness Scale in Zimbabwe. The Revised UCLA Loneliness Scale and the eight-item short form were highly correlated, but this association was spuriously elevated by the fact the eight-item short form is part of the full scale. Factor analysis of the eight-item short form suggested that this scale does not consistently reflect the factor structure of the full scale. We concluded that the Revised UCLA Loneliness Scale possesses acceptable reliability and factorial validity in Zimbabwe and that the eight-item version is superior to the four-item form of the Revised UCLA Loneliness Scale as a short loneliness measure. However, additional refinements may be needed to further improve the eight-item short version.

Adolescent

Development of Health Systems Research and National HSR networking in Zimbabwe.

Health Systems Research (HSR) aims at improving the quality of health care delivery through health managers with a management tool for decision making. Since 1988, over 100 health cadres from provincial and district health teams, central hospitals and municipalities have received training in HSR methodology. This training has resulted in the implementation of 12 research projects with the results being used to solve immediate problems identified. The development of HSR in Zimbabwe has focused on training priority setting for essential health research and the development of infrastructure and local resource groups to sustain the initiative. The HSR unit in conjunction with the Medical Research Council of Zimbabwe (MRCZ) have developed a computerised databank for keeping track of all health and medical research conducted in the country. The databank is a mechanism for co-ordinating and promoting research through minimising duplication of research effort in the dissemination and utilisation of research findings. Prospects for HSR in Zimbabwe are good; further development requires adequate funding, networking of all research groups and a national commitment to build a critical mass of trained health research manpower at all levels.

Decision Support Systems, Management

Drug use and anticipated parental reaction among rural school pupils in Zimbabwe.

Study participants included 285 secondary school pupils in Zimbabwe who responded to a questionnaire assessing alcohol, tobacco, and marijuana use, and anticipated parental reaction to the pupil's drug-taking behavior. Results showed nearly 17% of the sample had used alcohol, 8% used tobacco, and 5% had used marijuana during the past seven days prior to questionnaire administration. Results regarding intentions to use alcohol, tobacco, and marijuana in the future show pupils' interest highest in using alcohol. Nearly 34% indicated intentions to use alcohol during the next year, while 16% reported intentions to use tobacco, and 12.9% indicated intentions to use marijuana. Nearly 17% reported they felt their parents would be favorable to their use of alcohol. Anticipated parental approval for tobacco and marijuana was 13.6% and 10.8%, respectively. Though current use and future intentions among the sample are not as high compared to similar populations in developed countries, this study suggests Zimbabwe should consider expanding its drug education effort in the school setting. Research to identify effective educational strategies to curb further increases in adolescent drug taking behavior also needs to be explored and identified.

Adolescent

Cancer of the oesophagus in Zimbabwe.

Data for oesophageal cancers were requested from the Cancer Registry of Zimbabwe for the three years 1986-1988. There were 437 cases notified compared with 783 cases recorded in the Government's Statistical returns. There was a ratio of 6.9 males to one female accounting for 13.2 pc of all reported cancers in males and 1.7 pc of cancers in females. Prevalence increased with age to a rate of around 83 per hundred thousand in men aged 55 and older and 19 per hundred thousand in women over 65 years old. Notifications are only received from the Central Hospitals in Harare and Bulawayo. Addresses were not available for 31 pc of patients so that geographical variations could not be determined accurately. However, higher rates occurred in Harare and in the Mashonaland Provinces. It is recommended that cancer notifications should be obtained from all Government, Mission and Private hospitals in Zimbabwe.

Adult

Progress in the control of schistosomiasis in Zimbabwe since 1984.

Schistosomiasis remains the second most important parasitic disease in Zimbabwe. In terms of its combined morbidity and prevalence, schistosomiasis is thought to be the most important helminth infection of man. Since 1984, a number of control programmes have commenced around the country and a national control programme aimed at reducing morbidity is being implemented. The strategy adopted in Zimbabwe is a community based approach integrated in the primary health care system.

Child

Zimbabwe National Cancer Registry: summary data 1986-1989. National Cancer Registry Advisory Committee.

The Zimbabwe National Cancer Registry began operation in 1986. Between 1986-1989, a total of 8 276 cases were identified. Among men of African descent, oesophageal (11.2 pc) and liver cancer (11.0 pc) were most common. Cervical cancer was by far the most common among women of African descent (34.5 pc). Among both males and females of non-African descent, skin cancers (other than melanoma) accounted for one-third of cancers followed by prostate cancer (7.7 pc) in males and breast cancer (18.5 pc) in females. These findings are comparable to earlier reports of the epidemiology of cancer in Zimbabwe.

Causality

A three-year prospective study of 137 cases of acute leukaemia in Zimbabwe.

We studied 137 cases of acute leukaemia seen between December 1985 and November 1988, using traditional staining techniques together with cytochemistry and in cases of probable acute lymphoblastic leukaemia (Sudan Black negative) by immunophenotyping. Not all tests were carried out in every case (some cases of ALL could only be classified as T or non-T). Paediatric group (age less than or equal to 14 yrs): 75 cases--acute lymphoblastic leukaemia 52, acute myeloid leukaemia 18, acute undifferentiated leukaemia 5. Peak incidence in 5-9 year group. Male:Female ratio = 1.7:1. acute myeloid leukaemia was associated with chloromas in 2 cases (11 pc). Adult group: 62 cases--acute lymphoblastic leukaemia 23, acute myeloid leukaemia 36 and acute undifferentiated leukaemia 3. Peak incidence in 50-54 age group. Male:Female ratio = 1:1.2. Acute lymphoblastic leukaemia subtypes (all ages) T 16, Common 20, Null 12, 'non-T' 16, B cell 0, untyped 11. 69 pc were of L2 morphology. In T-ALL, 11 had thymomas and Male:Female ratio = 15:1. Male:Female ratio for 'non-T' = 1.5:1. Acute myeloid leukaemia subtypes (all ages) M1 3, M2 8, M3 14, M4 19, M5 8, M6 2, M7 1. Overall incidence of acute leukaemia appears increased at 0.91 per 100,000 per annum from previous studies in Zimbabwe. Common ALL (mean age = 13 years) is an emerging problem and now outnumbers T-ALL (mean age = 10 years). This may be related to a general improvement in living standards and health in Zimbabwe.

Acute Disease

The pattern of poisoning from traditional medicines in urban Zimbabwe.

A 10-year (1980-1989 inclusive) retrospective study was carried out at Zimbabwe's six main urban hospitals to evaluate the epidemiology of poisoning caused by traditional medicines. A total of 1456 cases were recorded, and this represented 23% (the biggest single group) of all poisoning cases. Sixty-seven per cent (982) of the patients were male and 33% (474) were female. The majority of patients (53%; 776) were under 5 years of age; 18% (264) were 21-30 years old; the 31-40-year age group accounted for 9.1% (132) of patients, and the 11-20-year age group for 6.7% (97). A mere 1.5% (22) of patients were over 60. Sixty-one per cent (892) of all cases were of poisoning associated with medication (treatment) and 8% (113) were accidental poisonings, while suicides and parasuicides accounted for 0.2% (3) and 2% (30) respectively. The mortality rate was 6% (2% of deaths were accidental and/or treatment-related). The main reasons for seeking treatment with traditional medicines were for depressed fontanelles and fever in children and diarrhoea and abdominal pain in adults. Treatment consisted mainly of supportive therapy and involved the induction of vomiting with ipecacuanha in children. This study indicates that the use of traditional medicines is common in Zimbabwe.

Adolescent

The pattern of poisoning in urban Zimbabwe.

A 10-year (1980 to 1989 inclusively) retrospective analysis of poisoning admissions to the six major referral hospitals in Zimbabwe revealed 6018 cases. The majority of the patients were aged 0-5 years (35%) and 21-30 years (22.6%). The main agents associated with acute poisoning were traditional medicines (22.9% of the total), household chemicals (18.8%, 13.2% of which was due to paraffin), snake and insect envenomation (17.1%), orthodox medicines (16.7%) and insecticides (14.8%, 10% of which is accounted for by organophosphates). Mortality was 15% and the main agents associated with fatality were pesticides, traditional medicines and orthodox medicines, in descending order. The prevention and treatment of intoxication caused by traditional and orthodox medicines, the proper storage and disposal of pesticides and legislation regulating their sale and distribution are of high priority in the fight to reduce poisoning caused by these agents.

Adolescent

The use of time-series analysis to forecast bont tick (Amblyomma hebraeum) infestations in Zimbabwe.

Studying the dynamics of tick infestations on cattle is an essential step in developing optimal strategies for tick control. Successful strategic tick control requires accurate predictions of when tick infestations will reach predetermined threshold levels. In the case of Amblyomma hebraeum, earlier work has shown that there is no consistent pattern of seasonal activity. This means that a statistical model for predicting A. hebraeum infestations cannot reliably use climatic factors as the only independent variables. An alternative method is to apply time-series, or auto-regressive moving-average (ARMA), analysis which uses only the past population patterns to predict future trends. This technique was applied to a data set consisting of 108 weekly tick counts of A. hebraeum (adult males, standard females, flat females and standard nymphs), conducted at an experimental station in southeastern Zimbabwe. The ability of the ARMA models to fit and predict actual tick infestations was judged using two sets of criteria. The first set focused on the goodness-of-fit, and used the adjusted R2 values, Q statistic and the Akaike Information Criteria. The second set of criteria measured the forecasting accuracy of an estimated equation, and consisted of regressing a 9-period forecast against an actual out-of-sample data set not used in the estimation process. The root mean square error of the forecast was also considered when comparing several models for the same data set. Using these criteria, the models estimated using the ARMA technique were judged to both fit and forecast with sufficient accuracy to warrant their use in strategic tick control. Although the success of using ARMA to forecast A. hebraeum is partly due to the non-seasonal behavior of the species, the results presented here suggest that it is worthwhile exploring the use of ARMA techniques to model the dynamics of other tick species. Where independent variables exert considerable influence on the dynamics of a tick species, these variables can be incorporated into an ARMA-style model.

Animals

An outbreak of haemorrhagic septicaemia (septicaemic pasteurellosis) in cattle in Zimbabwe.

An outbreak of haemorrhagic septicaemia caused by Pasteurella multocida in beef cattle in Zimbabwe grazing effluent-irrigated pastures, is described. The outbreak occurred during the wet summer months and predisposing stress factors included excessive rainfall and unusual cold weather during the preceding month. History, clinical features and post-mortem findings were consistent with reports of the disease from other countries, except that meningitis was also a constant feature. Morbidity approached 77% and mortality 5 per cent. Prophylactic treatment and vaccination with a killed bacterin together with a return of warmer and drier weather were probably important in halting the outbreak.

Age Factors

Reproduction in female cattle in a communal farming area of Zimbabwe.

Cattle in a communal farming area of Zimbabwe were identified and examined in the late dry and mid wet season of 1985/86. Ovarian activity rates were 17.9% and 38.6% in the dry and wet season respectively. Pregnancy rates were 16.1% and 24.6% respectively. A major limitation to reproduction was the percentage of anoestrous females. There was no evidence of a seasonal calving pattern. Median body condition score was 2.0 in the dry season and 1.5 in the wet season. Adult females of body condition score 2.5 and above had ovarian activity rates of 41.9% and pregnancy rates of 41.9 per cent. Those with a body condition score below 2.5 had rates of 26.8% and 16.4% respectively. Serum progesterone levels in pregnant animals were positively related to body condition score, with some animals having progesterone levels similar to non-pregnant animals. Metabolic profiles suggested that the major limiting nutrient in both seasons was nitrogen, although other micronutrients might also be involved in low reproductive rates.

Agriculture

Maternal height and age: risk factors for cephalopelvic disproportion in Zimbabwe.

Maternal age and stature are among several factors used to screen pregnant women for potential risk of labour complications. In a population-based case-control study in Harare, Zimbabwe, multivariate analysis was carried out to evaluate the importance of maternal age and height as risk factors for cephalopelvic disproportion (CPD). Using data abstracted from the medical records of 203 women with operative deliveries due to CPD and 299 women with normal unassisted vaginal deliveries, multiple logistic regression models were developed. Although maternal age < 18 years was not a significant risk factor in this study (perhaps because there were few women in this age group), advanced maternal age (> or = 35 years) was associated with a relative risk of 2.7 compared to women 20-34, after adjusting for other demographic and obstetric factors. Maternal height < 160 cm was associated with a twofold increased risk of CPD as compared to taller women.

Adolescent

Distribution of HLA-DQA1, -DQB1 and DRB1 alleles in black IDDM patients and controls from Zimbabwe.

We have used the XI Histocompatibility Workshop sequence-specific oligonucleotide probes to determine the DRB1, DQA1 and DQB1 genotypes by dot-blot hybridization of polymerase chain reaction (pcr)-amplified material from a homogenous black population in Zimbabwe. The DR4 subtype DRB1*0405, the DR3 subtype DRB1*0301, DQB1*0201 and DQB1*0302 and DQA1*0301 and DQA1*0501 were significantly increased in the IDDM group compared to the controls, whereas DRB1*11, DQB1*0602 and DQA1*0102 were significantly decreased. Taken together, the data show that susceptibility and resistance to IDDM are associated both with particular haplotypes and DQA1-DQB1 heterodimers without one or other being overriding.

Adult

Pathogens in dog bite wounds in dogs in Harare, Zimbabwe.

Over a year swabs were taken from 87 untreated bite wounds in dogs seen by veterinary practitioners in Harare, Zimbabwe. Swabs were also taken from normal skin adjacent to the wound site, and gingival swabs were collected from normal dogs coming to the same clinics. The swabs were cultured aerobically for pathogens, particularly Staphylococcus intermedius, and the antibiotic sensitivities of the pathogens were determined by disc diffusion assay. The most common pathogens isolated from the wounds were S intermedius (23 per cent), Escherichia coli (18 per cent) and non-lactose-fermenting coliforms (14 per cent). S intermedius was common on the normal skin of the dogs with infected wounds, and was associated with wounds on the abdomen, hindlimbs and tail and wounds that were more than three days old. This organism was, however, isolated only infrequently from the gums and there was little correlation in general between the prevalence of pathogens in the mouth and their prevalence in wounds. Of the S intermedius isolates from wounds, 30 per cent were resistant to penicillin and multiple antibiotic resistance was common among the enterobacterial isolates. The majority of the pathogens were sensitive to cotrimoxazole.

Animals

Aspects of orthodox medicines (therapeutic drugs) poisoning in urban Zimbabwe.

1. A retrospective study (extending over 10 years, 1980 to 1989 inclusively) of hospital admission cases, due to therapeutic drug poisoning was carried out at the six main hospitals of Zimbabwe's four cities. 2. The four cities have a total population of approximately 4 million. 3. A total of 1061 cases were recorded and analysed. This constituted 16.7% of all poisoning admission cases (i.e. the fourth biggest cause of poisoning after traditional medicines, household chemicals and snake/insect venom). 4. Of the 1061 cases, 31% were aged 21-30 years, 21.9% were aged 11-20 years, 14.9% were aged under 5 years and 12.8% were aged 31-40 years. Those aged over 80 years accounted for only 0.6% of the cases. 5. The major groups of drugs implicated were: the analgesics, 22% of the total; sedatives and hypnotics, 13.2%; antipsychotics, 11.6%; antimalarials, 9.3%; antidepressants, 9.0%; antimicrobials, 7.5%; and alcohol, 7.1%. The other drugs each accounted for the less than 7%; the least used group were the gastrointestinal drugs which formed only 0.6% of the total. Poisoning due to drug abuse was cited at 1.3%. Overdose, either accidental or in the course of treatment, accounted for 63.5% of the cases. 6. The mortality rate was 3.9% and most of the deaths were suicides. 7. Treatment consisted mainly of the administration of ipecacuanha in those under 5 years old age and supportive therapy in adults. A few cases were given an antidote if it was specifically indicated.

Adolescent

A pattern of acute poisoning in children in urban Zimbabwe: ten years experience.

1. A retrospective analysis was performed to evaluate the epidemiology of poisoning in children based on admissions to six of Zimbabwe's main urban hospitals over a 10-year period from 1980 to 1989 inclusive. 2. A total of 2873 cases were children aged between 0-15 years. This constituted 47.8% of poisoning cases from all age groups (6018) recorded during the study period. 3. All of the children (0-15 years) had signs and symptoms of poisoning on admission and, depending on their severity, were admitted to a ward or to an intensive care unit. A total of 4.9% (141) died. Most of those who died were suicide cases among the 11-15 year age group and accidental poisonings among the 0-15 year old group. 4. The under 0-5 age group constituted the majority of cases (75.4%) in the 0-15 age group, and most were between 1 and 3 years old. The 6-10 and 11-15 age groups formed 12.6% and 12% of the cases, respectively. The sex distribution showed that 53.1% were male. 5. Most incidences were accidental (93.2%). Suicides and parasuicides accounted for 1.9% and there were only two homicides. 6. The commonest toxic agents were: household products (27.2%), traditional medicines (23.%), venoms from snake bites and insect stings (16%) and therapeutic agents (12.4%). Of the therapeutic agents the most frequently implicated were antipsychotics 18.9%, analgesics 16.8%, anti-infectives 11.7%, anticonvulsants (8.2%) and benzodiazepines (7.7%).(ABSTRACT TRUNCATED AT 250 WORDS)

Acute Disease