Search PubMed⌕ Search

SEARCH · Search PubMed

Results for “Water”

Search indexed PubMed citations on genomics, clinical trials, systematic reviews and public health. Explore titles, authors and supplied subject terms, then open the PubMed record.

Quote a phrase for an exact phrase match. Source license links do not imply unrestricted reuse.

At least 19 recordsLinked to original sources

Evaluation of the contents of mineral water, spring water, table water and spa water.

The present study surveys and evaluates the mineral contents of the speciality drinking waters currently available in Germany. A total of 257 producers and 226 reports of water contents have been consulted. The minerals sodium, calcium, potassium and magnesium together with the halogens chlorine and fluorine have been of special interest here in view of their significance in infant feeding, caries prevention, and possible influence on the drinking waters, the sodium concentrated from 0.9 mg/l (Finkenbachquelle, mineral water) to 12830 mg/l (Bad Mergentheimer Albertquelle, spa water). The potassium values also, range broadly, between 1.4 mg/l (Kisslegger Sprudel, mineral water) and 611 mg/l (Obenauer Löwensprudel, mineral water). Fluoride concentrations were given special attention, since they are of significance in caries prevention, for the strength of bones, and also considerable importance in connection with the danger of fluorosis. Numerous commercial mineral waters and table waters contain too little fluoride (0.007 mg/l, Kirkeler Waldquelle, mineral water) or have fluoride concentrations over 4.1 mg/l (Hardenstein Brunnen, mineral water). The latter appear inappropriate, especially for small children. On the basis of the considerable variations of mineral and halogen contents in commercial mineral waters and table waters, the concentration of crucial trace elements should be clearly stated on the labels of the bottles, along with relevant information concerning possible effects.

Drinking↗

[Bacterial regrowth in drinking water. IV. Bacterial flora in fresh and stagnant water in drinking water purification and in the drinking water distribution system].

Six dead end water pipes were installed inside a Zurich drinking water plant and five others over a distance of 12 km along the distribution system and the water was left stagnating in there for 2 weeks. A total of 1508 bacteria from fresh and stagnating water were isolated and identified. Of these, 241 bacterial isolates from the distribution system were examined using the nutrient-tolerance test, i.e. testing the ability to grow in tap water and in media with low and very high nutrient content. In the fresh water of the treatment plant specific bacterial populations were obtained, these occurring particularly after the filters. According to different chlorine dosage and chlorine demand, they were finally washed into the distribution system in varying amounts and compositions. It was shown that in the fresh water of the distribution system the genera of Pseudomonas, Azotobacter and Actinobacteria were each present at a level of approximately 30%. After two weeks stagnation non-fluorescing pseudomonads were dominating in the treatment plant as well as in the fresh water of the distribution system. All isolated Actinobacteria and Azotobacter and almost half of the Pseudomonads proved to be oligotrophic oligocarbotolerants or oligocarbophilic organisms in the nutrient-tolerance test. The other half of the Pseudomonads plus the Flexibacter species were mesotrophic oligocarbotolerants, since they could grow in tap water and in culture media with very high nutrient content. Attention is drawn to the unrecognized danger of recontamination of mesotrophic bacteria growing rapidly in stagnating drinking water, which is used as rinsing water for cleaning food processing equipment.

Acinetobacter↗

The influence of water on the rates of 1,3-dipolar cycloaddition reactions: trigger points for exponential rate increases in water-organic solvent mixtures. Water-super versus water-normal dipolarophiles.

The nature of the rate enhancements caused by gradually increasing the mole fraction of water in the solvent (from 0 to 1) for the cycloaddition reactions of pyridazinium-dicyanomethanide 1,3-dipole, 2, with the dipolarophiles ethyl vinyl ketone (a water-super dipolarophile) and methyl acrylate (a water-normal dipolarophile) in the organic solvents acetonitrile, acetone, methanol, ethanol, and tert-butyl alcohol at 37 degrees C are explored. In each case as the mole fraction of water surpassed ca. 0.9, exponential rate enhancements were triggered. When methanol replaced water, the rate enhancements were smaller, and no triggering effect was observed. The dramatic rate enhancement triggered for the water-super dipolarophile was significantly reduced as the temperature was raised in the range 29-64 degrees C. The results suggest that a dominant hydrogen-bonding effect operates in water-induced rate enhancements of 1,3-dipolar cycloaddition reactions with water-super dipolarophiles as well as the hydrophobic effect. The hydrogen-bonding effect involves secondary bridging hydrogen bonding from the primary water-solvation shell of the transition state and the growth of structured water clusters. Theoretical calculations strongly support these conclusions.

Journal Article↗

[Investigation of Cryptosporidium spp. oocysts in tap water, well water, sewage water and sea water in Mersin, Turkey.].

Cryptosporidium spp. are protozoa which only live in a host cell and may cause an infection that may result in the death of people with immune deficiency. It is known that Cryptosporidium parvum and Cryptosporidium hominis infections may be spread by contaminated well and tap waters. The facts that there is no certain and reliable cure and that the organisms may be found asymptomatically in the healthy people increases the importance of cryptosporidiosis. Our study has been performed in the city of Mersin and surrounding areas. A total of 100 samples of water were taken from taps (44 samples), wells (2 samples), the sea (35 samples) and sewage (19 samples) to investigate the presence of Cryptosporidium oocysts. Cryptosporidium oocysts have been detected in 5 samples of tap water, one sample of well water, one sample of sea water and 4 samples of sewage water.

English Abstract↗

Studies on the adjuvant effect of water-in-oil-in-water (w/o/w) emulsion of sesame oil. 1. Enhanced and persistent antibody formation by antigen incorporated into the water-in-oil-in-water emulsion.

Water-in-oil-in-water (w/o/w) emulsion developed in our laboratory is as effective as water-in-oil (w/o) emulsion of Freund's incomplete adjuvant (FIA) in the stimulation of antibody formation. The emulsion is prepared by redispersion of water-in-sesame oil emulsion of an antigen solution in phosphate buffered saline with emulsifier, Tween 80. The emulsion can be stored at 4 degrees C for at least 3 months without any evidence of change in the adjuvanticity and in the w/o/w state. Even a single injection of bovine serum albumin (BSA) in the w/o/w emulsion elicited a high antibody response in mice over the period of almost whole lifespan. 10 microgram BSA in w/o/w could stimulate antibody formation up to 2(12) in hemagglutination titer, while the same dose in free solution did not elicit any detectable antibody. The tissue reactions caused by the w/o/w emulsion at the injected site and in the regional lymph nodes were much less prominent than those by FIA.

Adjuvants, Immunologic↗

NTP Toxicology and Carcinogenesis Studies of Chlorinated Water (CAS Nos. 7782-50-5 and 7681-52-9) and Chloraminated Water (CAS No. 10599-90-3) (Deionized and Charcoal-Filtered) in F344/N Rats and B6C3F1 Mice (Drinking Water Studies).

Chlorine and chloramine are used as disinfectants in water supplies to prevent the spread of waterborne diseases. The U.S. Environmental Protection Agency and the U.S. Congress, through the Safe Drinking Water Acts and Amendments, initiated studies to determine the most effective way to disinfect water supplies and, at the same time, minimize any potential long-term health effects associated with direct chemical exposure or indirect chemical exposure through the formation of byproducts. As part of this evaluation, 2-year studies of chlorinated or chloraminated deionized charcoal-filtered drinking water were conducted in F344/N rats and B6C3F1 mice to determine the potential toxicity and carcinogenicity associated with prolonged exposure and eliminate possible confounding effects of byproducts of chlorination. Chlorinated Water Studies: Water containing 0, 70, 140, or 275 ppm chlorine (based on available atomic chlorine) was provided to groups of 70 F344/N rats or B6C3F1 mice of each sex for up to 2 years. Groups of 10 rats or mice of each sex were predesignated for evaluation at 14 or 15 weeks and 66 weeks. Survival at 2 years of rats and mice receiving chlorinated water was similar to that of the controls. Mean body weights of dosed male rats, high-dose female rats, and dosed mice were slightly lower than those of their respective control groups. There was a dose-related decrease in water consumption by rats and mice. Water consumption by high-dose rats during the second year of the studies was 21% lower than controls for males and 23% lower than controls for females; water consumption by high-dose mice was 31% lower than controls for males and 26% lower than controls for females. The incidence of mononuclear cell leukemia in mid-dose, but not high-dose, female rats was significantly higher than that in controls (control, 8/50; low-dose, 7/50; mid-dose, 19/51; high-dose, 16/50). The proportion of female rats that died of leukemia before the end of the study and the mean time for observation of animals dying with leukemia were similar among all dose groups and controls. Although the marginal increase in leukemia incidence in the mid- and high-dose female rats suggested a possible association with the administration of chlorinated water, the incidence of leukemia was not clearly dose related. There was no indication of reduced latency of leukemia, and the incidence of leukemia in concurrent controls was less than the mean for historical controls; furthermore, there was no supporting evidence of an effect in male rats. Thus, the marginal increase in leukemia incidence in female rats was considered equivocal evidence of carcinogenic activity. There were no neoplasms or nonneoplastic lesions in male rats or in male or female mice that were clearly associated with the consumption of chlorinated water. Chloraminated Water Studies: Water containing 50, 100, or 200 ppm chloramine was provided to groups of 70 F344/N rats or B6C3F1 mice of each sex for up to 2 years. The same control groups were used for the chlorinated water and chloraminated water studies. Groups of 9 or 10 rats or mice of each sex were evaluated at 14 or 15 weeks and 66 weeks. Survival at 2 years of rats and mice receiving chloraminated water was similar to that of the controls. Mean body weights of high-dose rats and dosed mice were lower than those of their respective control groups. There was a dose-related decrease in water consumption by rats and mice. Water consumption during the second year of the studies by high-dose rats was 34% lower than controls for males and 31% lower than controls for females; water consumption by high-dose mice was 42% lower than controls for males and 40% lower than controls for females. Mononuclear cell leukemia occurred with a marginally increased incidence in the mid- and high-dose female rats receiving chloraminated water (control, 8/50; low dose, 11/50; mid dose, 15/50; and high dose, 16/50). As in female rats receiving chlorinated water, the proportion of female rats that died of leukemia before the end of the study and t that died of leukemia before the end of the study and the mean time for observation of animals dying with leukemia were similar among all dose groups and controls. The marginal increase in leukemia incidence in females receiving chloraminated water was considered equivocal evidence of carcinogenic activity for the same reasons given for female rats receiving chlorinated water. There were no neoplasms or nonneoplastic lesions in male rats or in male or female mice that were clearly associated with the consumption of chloraminated water. Conclusions: Under the conditions of these 2-year drinking water studies, there was no evidence of carcinogenic activity of chlorinated water in male F344/N rats receiving 70, 140, or 275 ppm. There was equivocal evidence of carcinogenic activity of chlorinated water in female F344/N rats based on an increase in the incidence of mononuclear cell leukemia. There was no evidence of carcinogenic activity of chlorinated water in male or female B6C3F1 mice receiving 70, 140, or 275 ppm. Under the conditions of these 2-year drinking water studies, there was no evidence of carcinogenic activity of chloraminated water in male F344/N rats receiving 50, 100, or 200 ppm. There was equivocal evidence of carcinogenic activity of chloraminated water in female F344/N rats based on an increase in the incidence of mononuclear cell leukemia. There was no evidence of carcinogenic activity of chloraminated water in male or female B6C3F1 mice receiving 50, 100, or 200 ppm.

Journal Article↗

Ion-water and water-water interactions in a gramicidinlike channel: effects due to group polarizability and backbone flexibility.

In the gramicidin channel, ionic transport and water transport occur simultaneously. Gramicidin's transport properties are influenced by ionic interactions with both the polypeptide and the channel waters. We present results of molecular dynamics studies on a series of alkali metal ions interacting with a water-filled gramicidinlike channel (a configurationally constrained polyglycine analog) at the dimer junction, in mid-monomer, and near the channel entrance. We investigate details of both short and long range ion-water and water-water correlation; these are notably dependent on the explicit consideration of polarizability and the degree of backbone flexibility. The nature of ion-water and water-water correlations changes as ionic size decreases and these changes may be augmented or attenuated by manipulation of the two parameters under study. Incorporating polarizability generally shortens ion-water distances and enhances ion-induced electrostriction (decreased water-water separations), while simultaneously reducing the long range orientational correlation of the single filing waters within the channel. Increasing flexibility predictably results in a broadening of the distribution of water-water and ion-water separations and contributes to the loss of long range orientational correlations. Both effects are ion specific; Cs+ and Na+ interact with the channel in distinctly different ways, while K+ represents an intermediate case more closely resembling Cs+. Our results demonstrate that incorporation of polarizability in the potential function has significant effects on the properties of channel water and, consequently, on the ionic transport process. While ion-water and water-water distances are decreased due to this feature, thereby fostering longer ranged correlations within the channel, enhanced interactions between water molecules and peptide groups tend to mitigate this effect. Possible implications for the multiple occupancy states of gramicidin and long range information transfer via a single file water chain are considered.

Cesium↗

Water from (waste)water--the dependable water resource.

Water reclamation and reuse provides a unique and viable opportunity to augment traditional water supplies. As a multi-disciplined and important element of water resources development and management, water reuse can help to close the loop between water supply and wastewater disposal. Effective water reuse requires integration of water and reclaimed water supply functions. The successful development of this dependable water resource depends upon close examination and synthesis of elements from infrastructure and facilities planning, wastewater treatment plant siting, treatment process reliability, economic and financial analyses, and water utility management. In this paper, fundamental concepts of water reuse are discussed including definitions, historical developments, the role of water recycling in the hydrologic cycle, categories of water reuse, water quality criteria and regulatory requirements, and technological innovations for the safe use of reclaimed water. The paper emphasizes the integration of this alternative water supply into water resources planning, and the emergence of modern water reclamation and reuse practices from wastewater to reclaimed water to repurified water.

Conservation of Natural Resources↗

Hydrogen bond and residence dynamics of ion-water and water-water pairs in supercritical aqueous ionic solutions: dependence on ion size and density.

We have carried out a series of molecular dynamics simulations to investigate the hydrogen bond and residence dynamics of X(-)-water (X=F, Cl, and I) and pairs in aqueous solutions at a temperature of 673 K. The calculations are done at six different water densities ranging from 1.0 to 0.15 g cm(-3). The hydrogen bonds are defined by using a set of configurational criteria with respect to the anion(oxygen)-oxygen and anion(oxygen)-hydrogen distances and the anion(oxygen)-oxygen-hydrogen angle for an anion(water)-water pair. The F(-)-water hydrogen bonds are found to have a longer lifetime than all other hydrogen bonds considered in the present study. The lifetime of Cl(-)-water hydrogen bonds is shorter than that of F(-)-water hydrogen bonds but longer than the lifetime of water-water hydrogen bonds. The lifetimes of I(-)-water and water-water hydrogen bonds are found to be very similar. Generally, the lifetimes of both anion-water and water-water hydrogen bonds are found to be significantly shorter than those found under ambient conditions. In addition to hydrogen bond lifetimes, we have also calculated the residence times and the orientational relaxation times of water molecules in ion(water) hydration shells and have discussed the correlations of these dynamical quantities with the observed dynamics of anion(water)-water hydrogen bonds as functions of the ion size and density of the supercritical solutions.

Journal Article↗

Water mobility in poly(ethylene glycol)-, poly(vinylpyrrolidone)-, and gelatin-water systems, as indicated by dielectric relaxation time, spin-lattice relaxation time, and water activity.

The mobility of water molecules present in poly(ethylene glycol) (PEG)-, poly(vinylpyrrolidone) (PVP)-, and gelatin-water systems was determined by dielectric relaxation and 17O NMR spectroscopy. Water activity was also measured. Dielectric relaxation spectra indicate that all the polymer systems studied contained water exhibiting a dispersion at a frequency > 10(9) Hz; in other words, water with high mobility close to that of bulk water. The dielectric relaxation time of the highly mobile water increased as polymer concentration increased. The PVP- and gelatin-water systems also contained water exhibiting a dispersion at a frequency < 10(9) Hz, which can be considered to be "bound water" with a restricted mobility because of its association with polymer molecules. Dielectric relaxation spectroscopy was used to determine water mobility separately for the populations of highly mobile water and bound water, whereas NMR relaxation spectroscopy was used to determine the average mobility of both populations. The spin-lattice relaxation time of water in these polymer-water systems showed a deviation from the isotropic two-state model. Dielectric relaxation data indicate that this deviation can be ascribed to variations in the relaxation time of highly mobile water caused by a change in polymer concentration. The dielectric relaxation time of highly mobile water in the gelatin system did not change with a change in polymer concentration to the extent that it did in the PEG and PVP systems. This result is consistent with a slight change in water activity of the gelatin system with increasing polymer concentration.(ABSTRACT TRUNCATED AT 250 WORDS)

Chemical Phenomena↗

Investigation on water consumption characteristics and water use efficiency of poplar under soil water deficits on the Loess Plateau.

The water consumption characteristics and water use efficiency (WUE) of poplar (Populus simonii) were investigated under the condition of three different soil water regimes, which were 70%, 55% and 40% of field capacity (FC), respectively. The results showed that water potential, water content, photosynthetic rate, WUE of leaves, and plant growth rate decreased significantly with reduction in soil water content. At the level of adequate and medium soil water content, rapid growth and biomass accumulation in poplar occurred during May and June, whereas this phenomenon occurred only during May under severe soil drought condition. Total water consumption and biomass growth were the greatest under adequate soil water condition, decreased under medium soil drought condition, and lowest under severe soil drought condition. Total WUE was the highest under medium soil water condition and lowest under severe soil condition. Changing patterns of water consumption for daily rate, every 10-day rate, and month rate were quite different under these three soil water regimes. For all these three treatments, the highest monthly water consumption rate occurred during July and June. The highest water consumption over a 10-day period was during in the second 10 days of July, the first 10 days of July, and the last 10 days of June for these three treatments, respectively. The day for the highest water consumption in the medium and severe drought treatments occurred 1 or 2 months earlier than the adequate soil water treatment. The daily time for the greatest water consumption was different throughout the life span of poplar under these soil water levels. According to these results, we concluded that poplar did not have the characteristics of drought-resistance plants, and we do not recommend that this tree species be planted over a wider range of the Loess Plateau in China.

Biomass↗

Mapping the energetics of water-protein and water-ligand interactions with the "natural" HINT forcefield: predictive tools for characterizing the roles of water in biomolecules.

The energetics and hydrogen bonding pattern of water molecules bound to proteins were mapped by analyzing structural data (resolution better than 2.3A) for sets of uncomplexed and ligand-complexed proteins. Water-protein and water-ligand interactions were evaluated using hydropatic interactions (HINT), a non-Newtonian forcefield based on experimentally determined logP(octanol/water) values. Potential water hydrogen bonding ability was assessed by a new Rank algorithm. The HINT-derived binding energies and Ranks for second shell water molecules were -0.04 kcal mol(-1) and 0.0, respectively, for first shell water molecules -0.38 kcal mol(-1) and 1.6, for active site water molecules -0.45 kcal mol(-1) and 2.3, for cavity water molecules -0.55 kcal mol(-1) and 3.3, and for buried water molecules -0.56 kcal mol(-1) and 4.4. For the last four classes, similar energies indicate that internal and external water molecules interact with protein almost equally, despite different degrees of hydrogen bonding. The binding energies and Ranks for water molecules bridging ligand-protein were -1.13 kcal mol(-1) and 4.5, respectively. This energetic contribution is shared equally between protein and ligand, whereas Rank favors the protein. Lastly, by comparing the uncomplexed and complexed forms of proteins, guidelines were developed for prediction of the roles played by active site water molecules in ligand binding. A water molecule with high Rank and HINT score is unlikely to make further interactions with the ligand and is largely irrelevant to the binding process, while a water molecule with moderate Rank and high HINT score is available for ligand interaction. Water molecule displaced for steric reasons were characterized by lower Rank and HINT score. These guidelines, tested by calculating HINT score and Rank for 50 water molecules bound in the active site of four uncomplexed proteins (for which the structures of the liganded forms were also available), correctly predicted the ultimate roles (in the complex) for 76% of water molecules. Some failures were likely due to ambiguities in the structural data.

Binding Sites↗

Water security in Uzbekistan: implication of return waters on the Amu Darya water quality.

GOAL, SCOPE AND BACKGROUND: Amu Darya river, one of the main water resources of Uzbekistan, shows a relevant longitudinal enrichment of soluble contents which strongly limits the human uses of its waters. Because of the low natural run-off processes, salts and pollutants are mainly driven to the river by the return waters used for washing and irrigating the surrounding lands. The influence of return waters on stream quality is dramatically relevant in the lower reaches of the river where almost all the flowing waters have been previously used for the agriculture practises. To provide analytical evidence on the potential effects of return waters on the quality of the Amu Darya river, the paper reports and comments data on salinity and metals contents of the waters flowing in the artificial channel network of Bukhara and in the Amu Darya river, from Bukhara up to the dam forming the Tuyamuyn Hydro Complex (THC). METHODS: A total of 15 sampling sites were selected for the analytical survey: Two sites were located on the Amu Darya river downstream from the inflow of the return waters from Bukhara, two in the river entering in the THC, and three downstream from the dam forming the reservoir complex. The waters entering and leaving the Bukhara agricultural area were sampled in two main collectors, while the waters flowing in the channel system were sampled in six distinct collectors. The following parameters were considered in the survey: pH, Oxygen, Hardness, Salinity, Conductivity, P-PO4(3-), P tot, N tot, N-NO3(2-), N-NO2-, COD, Ca2+, Mg2+, Fe, Mn, Zn, Cr, Cu, Ni, Cd, Pb. RESULTS AND DISCUSSION: Salt concentrations below 1000 mg/l were measured in the Amu Darya waters upstream to Bukhara. In the drainage system, salinity exceeds the palatability limit and reaches the maximum peak of 3200 mg/l in the outflow collector. Due to dilution effects, salinity returns to lower values (400-700 mg/l) along the Amu Darya river downstream from Bukhara; calcium and magnesium resulted the major constituents of the overall salinity. No serious metal contaminations were detected in the waters entering and leaving the examined channel system. Differently, the Amu Darya waters upstream to the THC showed a relevant metal contamination, with Cr, Ni, Fe concentrations exceeding the limits for human consumption. In the downstream sites, located in the Tuyamuyn Hydro Complex and in the Amu Darya river flowing out from this reservoir, excluding Fe, all the examined metals showed lover concentrations and values below the normative limits. CONCLUSION: The direct human consumption of the lower Amu Darya waters is strongly limited by salinity and by metal contamination. Although the salinity of the return waters from the Bukhara drainage system results in above normal limits, no corresponding increases were measured in the Amu Darya river downstream from the return water inflow at the time of the survey. As for the metal contamination of the Amu Darya river, the survey revealed the presence of relevant sources of metal contamination downstream from Bukhara external to the agricultural drainage system. This contamination resulted in reduced sedimentation processes taking place in the limnetic zones of the Amu Darya river upstream to the dam forming the Tuyamuyn Hydro Complex. RECOMMENDATION AND OUTLOOK: To fully understand the longitudinal increase of Amu Darya salinity, an evaluation of the cumulative effects of the loads from the main agricultural areas is required, also by using mass-balance models. As for the metals, an investigation should be addressed to identify the anthropogenic sources of contaminations present in the lower Amu Darya region and the metal loads should be diverted.

Agriculture↗

Response of the water status of soybean to changes in soil water potentials controlled by the water pressure in microporous tubes.

Water transport through a microporous tube-soil-plant system was investigated by measuring the response of soil and plant water status to step change reductions in the water pressure within the tubes. Soybeans were germinated and grown in a porous ceramic 'soil' at a porous tube water pressure of -0.5 kpa for 28 d. During this time, the soil matric potential was nearly in equilibrium with tube water pressure. Water pressure in the porous tubes was then reduced to either -1.0, -1.5 or -2.0 kPa. Sap flow rates, leaf conductance and soil, root and leaf water potentials were measured before and after this change. A reduction in porous tube water pressure from -0.5 to -1.0 or -1.5 kPa did not result in any significant change in soil or plant water status. A reduction in porous tube water pressure to -2.0 kPa resulted in significant reductions in sap flow, leaf conductance, and soil, root and leaf water potentials. Hydraulic conductance, calculated as the transpiration rate/delta psi between two points in the water transport pathway, was used to analyse water transport through the tube-soil-plant continuum. At porous tube water pressures of -0.5 to-1.5 kPa soil moisture was readily available and hydraulic conductance of the plant limited water transport. At -2.0 kPa, hydraulic conductance of the bulk soil was the dominant factor in water movement.

Biological Transport↗

Comparison of nitrate levels in raw water and finished water from historical monitoring data on Iowa municipal drinking water supplies.

Nitrate contamination of water sources is a concern where large amounts of nitrogen fertilizers are regularly applied to soils. Ingested nitrate from dietary sources and drinking water can be converted to nitrite and ultimately to N-nitroso compounds, many of which are known carcinogens. Epidemiologic studies of drinking water nitrate and cancer report mixed findings; a criticism is the use of nitrate concentrations from retrospective drinking water data to assign exposure levels. Residential point-of-use nitrate data are scarce; gaps in historical data for municipal supply finished water hamper exposure classification efforts. We used generalized linear regression models to estimate and compare historical raw water and finished water nitrate levels (1960s-1990s) in single source Iowa municipal supplies to determine whether raw water monitoring data could supplement finished water data to improve exposure assessment. Comparison of raw water and finished water samples (same sampling date) showed a significant difference in nitrate levels in municipalities using rivers; municipalities using other surface water or alluvial groundwater had no difference in nitrate levels. A regional aggregation of alluvial groundwater municipalities was constructed based on results from a previous study showing regional differences in nitrate contamination of private wells; results from this analysis were mixed, dependent upon region and decade. These analyses demonstrate using historical raw water nitrate monitoring data to supplement finished water data for exposure assessment is appropriate for individual Iowa municipal supplies using alluvial groundwater, lakes or reservoirs. Using alluvial raw water data on a regional basis is dependent on region and decade.

Cities↗

Understanding long-term baseflow water quality trends using a synoptic survey of the ground water-surface water interface, central Wisconsin.

The relationship between stream water quality and landscape activities is difficult to evaluate where the principal source of stream flow is ground water seepage because the average travel time from ground water recharge areas to stream discharge positions can be on the order of decades. We tested the idea that past and future baseflow water quality can be predicted based on a synoptic survey of ground water recharge age-dates (based on chlorofluorocarbon [CFC] measurements) and water quality measurements obtained at the ground water-surface water interface. In this study we (i) characterize the discharge-weighted age distribution and water quality of ground water seepage into the Little Plover River (LPR); (ii) use this information to backcast and forecast baseflow NO(3)(-) concentrations; and (iii) evaluate NO(3)(-) backcasts against historical baseflow data (1960 to 2000). The discharge-weighted apparent CFC age of ground water seepage into the LPR was 23.7 (+/-7) yr. Baseflow backcasts matched the four decade rise of baseflow NO(3)(-) from 2 to 8 mg L(-1). Baseflow forecasts included three scenarios. Scenario A projects the historical rise of NO(3)(-) in the LPR basin's ground water recharge through 2050. Scenario B projects a leveling off of NO(3)(-) in ground water recharge in the year 2000. Scenario C projects a leveling off in the year 1985. Under Scenario A, LPR baseflow NO(3)(-) will increase steadily from 8 to 19 mg L(-1) between 2000 and 2050. Under scenarios B and C baseflow NO(3)(-) will plateau at 13 mg L(-1) in 2030 and at 10 mg L(-1) in 2010, respectively. The approach developed in this study can be used to (i) reconstruct historical baseflow water quality patterns in the absence of long-term monitoring data and (ii) project the effects of potential management decision on future water quality.

Data Collection↗

[Study on the unscheduled DNA synthesis in primary rat hepatocyte induced by source water, tap water and active carbon-treated tap water].

To study the mutagenicity of source water with different turbidities, tap water and active carbon-treated tap water, unscheduled DNA synthesis in primary rat hepatocyte was detected. Increased unscheduled DNA synthesis was found in a dose-depend manner inducted by tap water, source water and tap water treated with 5, 10 and 15 milligrammes active carbon per liter water. The results also showed that the mutagenicity of the source water increased with the increasing of its turbidity, and mutagenicity of the tap water is higher than that of the source water as well. There was no unscheduled DNA synthesis in tap water followed by the treatment with 20 milligrammes active carbon per liter water. It is suggested that the development of the water treatment technics including sedimentation, filtration and treatment with active carbon is needed for decreasing or eliminating the mutagenicity of tap water.

Animals↗