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At least 19 recordsLinked to original sources

Protein deficiency and tribal warfare in Amazonia: new data.

Increasing numbers of anthropological studies about native Amazonian warfare and demographic practices attempt to explain these phenomena as competition over or a response to scarce game animals and other sources of high-quality protein. Recently completed field research among the Yanomamö Indians living at the Venezuela-Brazil border indicates that their protein intake is comparable to that found in highly developed industrialized nations and as much as 200 percent more than many nutritional authorities recommend as daily allowances. Recent data on other Amazonian tribes likewise fails to indicate a correlation between protein intake and intensity of warfare patterns.

Animals

Persistent trauma three decades after the Halabja massacre: psychological symptom profiles and hair cortisol levels in gas attack survivors.

BACKGROUND: Survivors of the 1988 Halabja chemical attack have experienced severe, chronic trauma, yet limited research has examined the long-term psychological and biological consequences of chemical warfare exposure more than three decades later. AIMS: To examine long-term post-traumatic stress disorder (PTSD) symptoms, depression/anxiety symptoms, somatic symptoms and perceived stress among survivors of the Halabja chemical attack, and to investigate the associations of trauma exposure, sociodemographic factors and hair cortisol concentrations (HCCs) with psychological symptom severity and symptom profiles. METHOD: A total of 209 survivors of the Halabja chemical attack participated in structured interviews using culturally adapted and field-tested instruments, including the Post-Traumatic Stress Disorder Checklist for DSM-5, Hopkins Symptom Checklist-25, the Patient Health Questionnaire-13, the Perceived Stress Scale-14 and an adapted War and Adversity Exposure Checklist-26. Hair cortisol and cortisone concentrations were assessed as biomarkers of chronic stress. Data were analysed using correlations, independent-samples t-tests, multiple linear regression analyses, multinomial logistic regression and latent profile analysis (LPA). RESULTS: Survivors demonstrated a substantial long-term psychological symptom burden. Overall, 87.6% of participants exceeded the cut-off for probable PTSD symptoms, and 75.1% exceeded the cut-off for elevated depression/anxiety symptoms. Most participants (81.8%) reported exposure to 11 or more lifetime traumatic events. Men reported significantly greater cumulative trauma exposure, whereas women reported significantly greater somatic symptom severity. Higher educational attainment and employment were consistently associated with lower psychological symptom severity across multiple outcomes. HCCs were not significantly associated with PTSD symptoms or latent symptom-profile membership after adjustment for trauma exposure and psychosocial variables. The LPA identified four symptom-severity classes characterised by differing levels of PTSD and depression/anxiety symptoms. Greater cumulative trauma exposure and lower social support were associated with membership in more severe symptom classes. CONCLUSIONS: Survivors of the Halabja chemical attack continue to experience substantial psychological distress more than three decades after exposure. Long-term symptom severity appears to be more strongly associated with cumulative trauma exposure and psychosocial adversity than with HCCs. The findings highlight substantial heterogeneity in symptom presentation and support the need for long-term, culturally sensitive and trauma-informed mental health interventions for survivors of chemical warfare and mass violence.

Halabja chemical attack

Reflections on military psychiatry.

The need for psychiatrists in the military was recognized for the first time during World War I, which involved millions of men in unusually protracted warfare. The policy of treating psychiatric casualties close to the from and returning soldiers to their military units as quickly as possible proved of great significance in the U.S. war effort. During World War II, the Korean conflict, and the war in Viet Nam, military psychiatry made great contributions and learned many lessions, both at home and abroad. The lessions learned by military psychiatry have important applications for the rest of medicine, especially in the fields of stress, crisis therapy, and community psychiatry.

Community Psychiatry

Some missile injuries due to civil unrest in Northern Ireland.

Some missile injuries are reviewed after nearly 8 years of continuous warfare. A feature of many of these injuries is the early admission to hospital which has had a profound effect on the survival rate and the recovery period. Some examples are given of injuries inflicted by rubber bullets. The effects of wounding by low and high velocity missiles are described and examples given. An injury caused by a missile incorporated in a bomb is also shown.

Adolescent

Colony-specific territorial pheromone in the African weaver ant Oecophylla longinoda (Latreille).

Major workers of Oecophylla longinoda mark their territories with persistent pheromones that are distinguishable to the ants at the colony level. Workers detecting the deposits of an alien colony respond with increased amounts of aversive and aggressive behavior, and they later recruit nestmates to the area at a higher rate. Colonies entering a field impregnated with their own scent also gain an initial advantage in warfare with other colonies. The pheromones are located at least in part in drops of rectal sac fluid deposited by workers over the territorial surface.

Animals

Effect of toxogonin and P2S on the toxicity of carbamates and organophosphorus compounds.

Toxogonin (80 mg/kg intraperitoneally) given 15 min. prior to the administration of organophosphorus insecticides dimethoate, malathion, parathion and azinphos-methyl, organophosphorus warfare agents soman and tabun, or carbamates physostigmine, pyridostigmine and aldicarb, reduced the toxicity in mice of these agents by increasing their LD50 dose 1.5-3 fold. The toxicity of the carbamate insecticide carbaryl, however, was significantly increased by toxogonin. Similar results were obtained for P2S (150 mg/kg intraperitoneally) with respect to the toxicity of dimethoate, soman and pyridostigmine, whereas no effect could be detected on the toxicity of tabun. Only a slight reduction in the toxicity of physostigmine was observed. The acetylcholinesterase activity in erythrocytes, cerebrum and diaphragm of surviving mice 20 hours after organophosphate intoxication was similar both in toxogonin and P2S treated animals and untreated animals.

Animals

A noncontiguous code for RNA-guided DNA recognition at the origin of CRISPR-Cas.

CRISPR-Cas provides RNA-mediated adaptive immunity, but how its first RNA-guided effector arose is unclear. In this study, we report the discovery of Viral Interference Programmable Repeat (VIPR) systems consisting of a Vipr protein ancestral to the earliest CRISPR-Cas effectors and VIPR RNAs (vrRNAs) comprising alternating GGY/NN motifs. Unlike canonical guide RNAs that pair with target nucleic acids through contiguous complementarity, vrRNAs recognize double-stranded DNA through a noncontiguous code in which the variable NN dinucleotides collectively specify a gapped target sequence. Natural vrRNA targets suggest that VIPR systems act against competing phages, and we demonstrate programmable phage defense by redirecting the complex for transcriptional repression. These results suggest that adaptive immunity originated from ancient warfare between viruses, revealing a previously unidentified logic for encoding information in sequence.

CRISPR-Cas Systems

Apartheid: focus on health.

This paper focuses on health in the Republic of South Africa and calls not only for technical warfare against disease, poverty, and bigotry but also for attention to predisposing causes of disease and ill health among the African majority.

Delivery of Health Care