Search PubMed⌕ Search

SEARCH · Search PubMed

Results for “Viral epidemiology”

Search indexed PubMed citations on genomics, clinical trials, systematic reviews and public health. Explore titles, authors and supplied subject terms, then open the PubMed record.

Quote a phrase for an exact phrase match. Source license links do not imply unrestricted reuse.

At least 19 recordsLinked to original sources
PubMed1978

The seroepidemiological pattern of acute viral hepatitis. An epidemiological study on viral hepatitis in the Hannover region.

The natural incidence of the etiologically distinct types of viral hepatitis was determined by investigating acute phase sera of symptomatic hepatitis cases occuring in the Hannover area in 1975 for the presence of hepatitis B surface antigen, antibodies to hepatitis A, hepatitis B core and surface antigens, and by measuring the IgM serum levels. Fourteen different seroepidemiologic patterns were recognized. Although there was a high prevalence of hepatitis A antibody in the population, the frequency of hepatitis A was low (n = 56) suggesting that the hepatitis A virus does not play a major role in symptomatic hepatitis in the Hannover area at present. Spread of the hepatitis A virus was mostly associated with person-to-person contact or tourist travel in southern Europe. Hepatitis B was the predominant type of hepatitis (n = 211). Hepatitis non-A, non-B was observed infrequently (n = 62). A high percentage of patients with hepatitis B and hepatitis non-A, non-B reported parenteral exposure to potentially contaminated materials. No other findings, however, suggested an infectious etiology of hepatitis non-A, non-B.

Antibodies, Viral↗
PubMed1977

[Role of the instrument transmission factor in the epidemiology of viral hepatitis. II. Methods, materials, chief results].

The authors conducted a prospective controlled epidemiological observation in two towns of the Moldavian SSR. There were 50 000 persons under observation. Over 300 000 parenteral manipulations carried out in them were recorded. Analysis of the materials obtained on the Minsk-22 computer demonstrated the same incidence of viral hepatitis in the groups given parenteral manipulations and without them. Consequently, the instrumental transmission factor had no essential significance in the epidemiology of viral hepatitis, this corresponding to the results of the authors' preceding theoretical study.

Adult↗
PubMedDate not supplied

The epidemiology of viral hepatitis: an overview.

Type A hepatitis maintains itself in human populations without either an extrahuman or human reservoir. Intestinal carriers do not appear to be epidemiologically important; viremic carriers have not been demonstrated. Person-to-person transmission by the fecal-oral route is the usual mechanism. Epidemic and endemic occurrence is usually recognizable by well-defined characteristics; a "hyperendemic" patern has been documented. In some countries, but not all, the long-term trend of type A disease has been downward in recent years. Type B hepatitis is worldwide in distribution, and capable of maintaining itself by the carrier reservoir. Transmission is by multiple mechanisms, with the percutaneous route still of major importance when adequately defined in terms of subtle exposures. Contact-associated transmission probably occurs by both the oral-oral and venereal routes. The long-term trend of type B hepatitis is unknown, but some evidence suggests an increase in the United States apart from the epidemic associated with drug abuse. The existence of additional viruses of human hepatitis is suggested by data concerning transfusion-associated disease and multiple episodes in the same individual.

Adolescent↗
PubMed2026

Oropouche virus: viral evolution, epidemiological trends, and challenges for control.

PURPOSE OF REVIEW: In recent years, OROV has emerged as a significant public health threat beyond the Amazon region. Here we review current epidemiological, virological, clinical and ecological knowledge of OROV to inform health practitioners, public health authorities and the scientific community and to facilitate the development of effective control strategies for OROV. RECENT FINDINGS: We describe the epidemiological, virological, ecological and clinical characteristics of OROV, focusing on lessons from the recent expansion, and highlighting needs for control and management of this emerging arbovirus. SUMMARY: This review aims to inform health practitioners, public health authorities and the scientific community of the recent reemergence and expansion of OROV beyond the Amazon Basin. The ecology, epidemiology, virology of OROV and clinical presentations of OROV infection are discussed, and knowledge gaps are identified.

Humans↗
PubMedDate not supplied

[Various problems of epidemiology of viral hepatitis].

Because a rise in incidence of virus hepatitis observed in some years and showing an epidemic nature begins in one year and continues in the first quarter of the following year, it is recommended to register the incidence not from January to December, but from July to June of the next year in studies of some regularities of the epidemic process. Also, since in Baku a rise in incidence begins in July, it is suggested that planned gamma globulin prophylaxis be carried out not in September, but in early July. It has been established that children under 14 have virus hepatitis type A 10--24.4 times as frequently as adults.

Adolescent↗
PubMed1977

[New findings in the epidemiology of viral hepatitis].

At present there is not yet a causal therapy of hepatitis. The modern state of knowledge on the mode of transfer, on the persistence of the causative organisms and the immunological reactions evoked by the causative organisms gives the possibility for new ways in prevention. The HBs Ag-carriers are a reservoir of causative organisms in the sense of chronic carriers. In a particular degree they endanger the personnel of public health. A supplementation of the general hygienic preventive measures by the immunoprophylaxis is desirable.

Acute Disease↗
PubMed1978

[Viral neuraxitis. Epidemiological and clinical aspects].

Seven cases of acute neuraxitis due to Coxsackie B3, 2 to mumps, 1 to measles, and 1 to influenza B observed in the province of Alessandria between Jan. 1975 and July 1977 are described. In the coxsackie cases, blood chemistry and clinical examinations were coupled with determination of serum levels of complement fixing, haemagglutin-inhibiting and neutralising antibodies on two successive specimens, isolation of virus from cerebrospinal fluid and faeces, and, in one case, from a cerebral biopsy specimen, and determination of cerebrospinal fluid IgA, IgG, and IgM. Some particularly interesting epidemiological, immunological and clinical features of teh series are discussed more fully.

Adolescent↗
PubMed2025

Wastewater Sequencing Reveals Persistent Circulation and Rising Prevalence of Several Oncogenic Viruses Across Texas.

BACKGROUND: Oncogenic viruses cause high-risk cancers in humans and are responsible for nearly 20% of all cancer cases worldwide. Currently, very limited data exists in the realm of wastewater-based viral epidemiology (WBE) of cancer-causing viruses, with existing studies using targeted approaches (i.e PCR-based approaches) which lack scalability. Our study aims to carry out WBE with hybrid-capture probes to detect and track multiple oncogenic viruses simultaneously in wastewater across Texas, USA, overcoming the drawbacks associated with targeted approaches. METHODS: Here, we used a hybrid-capture approach to detect, filter and sequence oncogenic virus signals from wastewater samples collected over a duration of three years, from May 2022 to May 2025. Once viral reads were sequenced, we utilized established computational tools to characterize reads into their respective virus of origin. Next, viral abundances of each characterized oncogenic virus were tracked over time and read coverage across their genomes was measured using read mapping techniques. FINDINGS: We detected six known oncogenic viruses, along with three suspected oncogenic viruses across all sampling locations within Texas. Over three years, viral abundance gradually increased, with distinct peaks and dips over the summer and winter months. The prevalence of high-risk viruses such as HPV and EBV rose sharply, with increases in abundance observed post-2024. We also obtained nearly 100% genome coverage with viral reads captured using a hybrid-capture technique for almost all oncogenic viruses and their types. INTERPRETATIONS: Our study shows that a hybrid-capture method can efficiently overcome the challenges faced with using targeted approaches for WBE. Using this method, we get broader read coverage, coupled with concurrent and consistent real-time tracking dynamics of multiple oncogenic viruses. Our findings also emphasize the persistent circulation and rising prevalence of high-risk cancer-causing viruses, underscoring the need for sustained public health interventions to protect communities and assess viral prevalence in high-risk populations. FUNDING: This work was supported by S.B. 1780, 87th Legislature, 2021 Reg. Sess. (Texas 2021), the Baylor College of Medicine and the Alkek Foundation Seed Funds.

Journal Article↗
PubMedDate not supplied

Epidemiological investigations on viral hepatitis in preschool and school communities. Note I. Prevalence and incidence of viral hepatitis and the role of the community in transmission.

A transversal and longitudinal epidemiological follow up was undertaken of the viral hepatitis cases occurring in two types of children communities (kindergartens and schools). The role of organized communities in the spread of hepatitis viruses and the contribution of external factors to the maintenance of hepatitis endemicity are discussed.

Child↗