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At least 19 recordsLinked to original sources
PubMed1978

[Controlled vacuum extraction by measuring the pressure exercised by the truss (author's transl)].

The article explains a method for measuring the adhesivity between the anterior part of the foetus and the suction bulb of the vacuum extractor described by Malmström (1). The cover plate of the suction bulb, which is fitted with an expanding measuring strip, is used for reading off the measurements. This enables a quantitative recording of the pressure existing between the foetal part and the truss which corresponds very closely with the adhesivity of the suction bulb to the anterior part of the foetus. The device allows control and recording by means of an instrument with indicator and scale and a recording device. In this manner, vacuum extraction can be subjected to continuous control, thus rendering this obstetric procedure safer and easier.

Extraction, Obstetrical↗
PubMed1990

Trusses.

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Equipment Design↗
PubMed1991

Trusses.

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Aged↗
PubMed1994

Digital rectal examination, serum prostate specific antigen, and prostatic ultrasound: how effective is this diagnostic triad?

Ninety-nine of 105 consecutive men who underwent transrectal prostatic ultrasound (TRUS) at Highland Park Hospital had the results correlated with digital rectal examination (DRE), serum prostate specific antigen (PSA), and biopsy results. Ninety-six cases had evaluable ultrasound studies. Thirty-two of the 99 who underwent biopsy had primary carcinoma of the prostate. Prostate volume, predicted PSA, a ratio of observed/predicted PSA, and Gleason score were examined. There was no correlation between age and prostate volume, volume and the presence of carcinoma, or PSA and Gleason score. Thirty-one point six percent of the abnormal DREs, 36.6% of the abnormal TRUSs, and 40.6% of the elevated PSAs occurred in men with prostatic carcinoma (PCa). If PSA was normal (less than or equal to 4.0 ng/ml) and either DRE or TRUS was abnormal, then the risk of carcinoma was 2.9%. If PSA was elevated, regardless of the other two tests, the risk of finding PCa was at least 38%. If all three tests were abnormal, the risk of carcinoma was 38% in our series and 68% in a meta-analysis. Many men with PSA values between 4 and 10 ng/ml have benign biopsies. However, close future follow-up with consideration of repeat biopsy should be strongly considered.

Aged↗
PubMed1981

Effect of early return to work after elective repair of inguinal hernia: Clinical and financial consequences at one year and three years.

Since January, 1976, male patients undergoing elective unilateral inguinal herniorrhaphy have been included in a trial to see whether early return to normal activity is associated with an increased recurrence rate and to investigate economic consequences. By June, 1981, 500 patients had been reviewed at one year. 2 patients had defaulted. The first 200 patients had been examined at one year and three years. Recurrence was assessed independently, and recurrences were found of which the patient was unaware. The acceptable definition of recurrence was need for reoperation or a truss. The overall recurrence rate at one year was 3.9%. At three years no further recurrences were detected in the first 200 patients. There was no difference in the recurrence rate for those in the "early" group with 8 recurrences in a total of 246 patients and 10 recurrences in 245 patients in the control group. the median inactivity period in the "early" group was 48 days, compared with 65 days in the control. This differences of 17 days is significant (p=0.001). The self-employed "early" group returned to work in a median of 31 days. One-third of workers were losing a median of pounds 31 per week (range pounds 3- pounds 200). Patients can return to normal activity sooner after inguinal herniorrhaphy than has been advised without increasing the recurrence rate at one year and three years and with considerable monetary benefit to one-third of workers.

Clinical Trials as Topic↗
PubMed1991

1H NMR studies of DNA recognition by the glucocorticoid receptor: complex of the DNA binding domain with a half-site response element.

The complex of the rat glucocorticoid receptor (GR) DNA binding domain (DBD) and half-site sequence of the consensus glucocorticoid response element (GRE) has been studied by two-dimensional 1H NMR spectroscopy. The DNA fragment is a 10 base-pair oligonucleotide, 5'd(GCTGTTCTGC)3'.5'd-(GCAGAACAGC)3', containing the stronger binding GRE half-site hexamer, with GC base pairs at each end. The 93-residue GR-DBD contains an 86-residue segment corresponding to residues 440-525 of the rat GR. Eleven NOE cross peaks between the protein and DNA have been identified, and changes in the chemical shift of the DNA protons upon complex formation have been analyzed. Using these protein-DNA contact points, it can be concluded that (i) the "recognition helix" formed by residues C460-E469 lies in the major groove of the DNA; (ii) the GR-DBD is oriented on the GRE half-site such that residues A477-D481, forming the so-called D-loop, are available for protein-protein interaction in the GR-DBD dimer on the intact consensus GRE; and (iii) the 5-methyl of the second thymine in the half-site and valine 462 interact, confirming indirect evidence [Truss et al. (1990) Proc. Natl. Acad. Sci. U.S.A. 87, 7180-7184; Mader et al. (1989) Nature 338, 271-274] that both play an important role in GR-DBD DNA binding. These findings are consistent with the model proposed by Härd et al. [(1990) Science 249, 157-160] and the X-ray crystallographic complex structure determined by Luisi et al. [(1991) Nature 352, 497-505].

Amino Acid Sequence↗
PubMed1990

Surface tension and the dodecahedron model for lung elasticity.

Macroscopic elastic moduli governing the incremental deformations of lung parenchyma are calculated on the basis of a model for an individual lung element in the shape of a regular dodecahedron. Elastic stiffness within the element is provided by pin-jointed tension members along the edges of the dodecahedron, surface tension is incorporated into its pentagonal faces, and the influence of transpulmonary pressure is simulated by an externally applied hydrostatic tension. The analysis is based on a variational statement of nonlinear structural mechanics, and the results show how the moduli depend on the effective inflation pressure, the constitutive behavior of the idealized truss members, and the surface-area dependent surface tension. The theory is discussed in the light of available experimental information. A more general analysis is needed to account for the effects of structural as well as surface-tension hysteresis.

Elasticity↗
PubMed1990

Nonlinear analysis of intervertebral disk under dynamic load.

This study pertains to the response of intervertebral joint under dynamic axial load. The numerical model represents two vertebral bodies with an interposed disk and uses three-dimensional elements. A transversely isotropic material law is adopted for cortical bone and an isotropic law for cancellous bone. Annulus collagen fibers are modelled using truss elements with no compressive resistance. The disk material is assumed hyperelastic, using a mixed finite element approach, allowing a representation of the disk involving the incompressibility characteristics for the material. The analysis considers finite displacement and strain fields under dynamic load. Intensity, trend and distribution of loads on the vertebral body are deduced from the literature. The problem is investigated with reference to different compressibility levels of disk material related to disk degenerationn phenomena.

Biomechanical Phenomena↗
PubMed1975

External herniae: ventral herniae and summary.

1. In three articles, inguinal, femoral, and ventral herniae have been discussed, one of the aims being to draw the attention of those who are new to surgery in the tropics to some of the things the author thought were peculiar to these herniae. Experiences in the 1,100-bed Korle Bu Hospital, Accra, where a retrospective survey showed that 609 external herniaw were mended in 15 months, formed the basis of the discussions. 2. The applied anatomy of the inguinal canal of adult Ghanaians was described. Three things were pointed out: the infantile type of inguinal hernia was the rule not the exception; the floor and the conjoint tendon were well developed and useful for repair; the pubic branch of the inferior epigastric artery was normal not aberrant. 3. IN Accra inguinal herniae are big and a man's disease. The differential diagnosis of scrotal hernia includes vaginal hydrocele, scrotal elephantiasis, testicular tumours, and tuberculous epididymoorchitis. A case was made in favour of differentiating between direct and indirect inguinal herniae preoperatively. 4. Elective herniorrhaphy was recommended as the treatment of choice and operative techniques were described. The suture material to employ for the Bassini repair must be non-absorbable, e.g. silk or nylon. Whereas herniotomy is adequate in children, in women herniorrhaphy is combined with clearance and obliteration of the inguinal canal. 5. The author did not recommend a truss for an inguinal let alone a femoral hernia. There is suggestive evidence that even in the tropics a man's hernia could be safely repaired on an out-patient basis. 6. Since femoral hernia is rare, it was recommended that in the interest of the patients, skillful surgeons should repair them. 7. The surgical anatomy of the femoral canal, and clinical features of femoral hernia were described. The differential diagnosis included inguinal hernia, abscesses in the groin, hydrocele of the femoral canal, saphena varix, lymphadenopathy, simple tumours and aneurysm of the femoral artery. 8. The treatment of choic is a surgical operation of which three were named and one described ("the low" operation of Lockwood). Recurrence is rare...

Cesarean Section↗
PubMed1992

[Mechanical principles of L-trapezoid compression plate in the fixation of trochanter fractures].

Three pairs of human cadaver femur were used for simulation electric test with load on both legs and single leg. An Evans III osteotomy was made, and stabilized with L-trapezoid compression plate (L-TCP). L-angled plate (L-AP) 95 degrees and 130 degrees respectively. The results demonstrated that the stability of fixation of L-TCP was significantly greater than L-AP. Since the cancellous screw of L-TCP can hold the proximal fragment and forms a stable triangular truss with the L end, the bony support of the medial posterior part can be reconstructed by holding the lesser trochanter with the lag screw. From June 1980 to August 1990, 68 patients with 71 trochanter fractures and osteotomies were treated with L-CTP. 54 patients with 57 fractures and osteotomies were followed up for 6-52 months. All fractures and osteotomies were healed. No bone cutting off failure was encountered. The hips and knees of 51 patients (54 limbs) (94.8%) showed excellent and good functions. Infection occurred in 3 patients (4.4%). Varus deformity developed in 2 patients with an Evans IV fracture, and plate fracture occurred in one of them.

Aged↗