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Results for “Trichomonas Infections”

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At least 19 recordsLinked to original sources
PubMed1989

Cervical intraepithelial neoplasia among women with papillomavirus infection compared to women with Trichomonas infection.

This study was undertaken to determine if women with papillomavirus infection were more likely to develop cervical intraepithelial neoplasia (CIN) than women with other sexually transmitted infections. Women with cytologic evidence of papillomavirus infection and a comparison group of women with cytologic evidence of Trichomonas infection were identified from a reexamination of cervicovaginal smears initially evaluated between 1973 and 1981 in a private pathology laboratory. To identify subsequent CIN among these women the authors reviewed records of private obstetric and gynecology practices and public clinics through 1983. After accounting for possible confounding variables, including age, marital status, frequency of cervical cytologic examination, and selected characteristics of pregnancy history, a 2.7-fold increase in the rate of CIN was found among the 613 women with prior papillomavirus infection compared to the 410 women with previous Trichomomas infection. The rate ratio was higher among women with more severe cervical neoplasia than for those with less severe neoplasia and for those followed for greater than 12 months than for those followed 7 to 12 months. The results of this study provide further evidence of the role of papillomavirus in the etiology of cervical cancer.

Adult↗
PubMed1991

[Therapeutic aspects of trichomonas infection of the female genitals].

Infection with trichomonas is a common event in patients in gynecologic practice. In patients in an outpatient department the incidence of trichomonas infection was 7%, in cases with other genital infections 16%. Especially in alcalic vaginal milieu and in Gardnerella infections higher rates of trichomonas could be observed. The recurrence rate after monotherapy was 8%.

Drug Therapy, Combination↗
PubMed1989

Trichomonas infections in men.

Trichomonas vaginalis, a common pathogen in the female genital tract, produces a characteristic clinical picture in women. Less well recognized are the manifestations of Trichomonas infestations of the male genital tract, which include urethritis and chronic prostatitis. Multiple-glass urinalysis and selective use of Trichomonas cultures may improve recognition of this organism in the family practice setting.

Adult↗
PubMed1999

Iron modulates phenotypic variation and phosphorylation of P270 in double-stranded RNA virus-infected Trichomonas vaginalis.

Trichomonas vaginalis infected with a double-stranded RNA virus undergoes phenotypic variation on the basis of surface versus cytoplasmic expression of the immunogenic protein P270. Examination of batch cultures by flow cytofluorometry with monoclonal antibody (MAb) to P270 yields both fluorescent and nonfluorescent trichomonads. Greater numbers and intensity of fluorescent organisms with surface P270 reactive with MAb were evident in parasites grown in medium depleted of iron. Placement of iron-limited organisms in medium supplemented with iron gave increased numbers of nonfluorescent trichomonads. Purified subpopulations of trichomonads with and without surface P270 obtained by fluorescence-activated cell sorting reverted to nonfluorescent and fluorescent phenotypes when placed in high- and low-iron media, respectively. No similar regulation by iron of P270 was evident among virus-negative T. vaginalis isolates or virus-negative progeny trichomonads derived from virus-infected isolates. Equal amounts of P270 were detectable by MAb on immunoblots of total proteins from identical numbers of parasites grown in low- and high-iron media. Finally, P270 was found to be highly phosphorylated in high-iron parasites. Iron, therefore, plays a role in modulating surface localization of P270 in virus-harboring parasites.

Animals↗
PubMed2004

[Molecular diagnosis of oral cavity trichomonas infections in HIV patients].

The occurrence of trichomonas in oral cavity of HIV patients is not well known. HIV patients often suffer from oral lesions (candidiosis, advanced caries) and it remains unclear if any oral parasites can affect that, therefore the aim of the study was verification of species that can occur in HIV patients' oral cavity. Diagnosis of oral trichomonas can be performed by conventional methods (microscopic observation of wet and stained preparations and cultivation) but these are time consuming and insufficient for proper species differentiation, therefore in order to detect and identify species of parasites precisely, molecular methods such as PCR (Polymerase Chain Reaction) and sequencing of its product, were applied. 54 HIV patients (18 females and 36 males at the age of 20-54) were examined. All of them were addicted to intravenous drugs for at least 6 years. Saliva, smears and spittle samples were collected and used for cultivation, preparations and molecular diagnosis. For PCR amplification a pair of primers (T1 and T2) specific for ITS 1 - 5.8 SrRNA - ITS 2 region was designed. The oral trichomonas were detected in saliva samples of 3 HIV patients; these were males at the age of 25, 27 and 44. The identification of species by PCR and sequencing of the PCR products showed the trichomonads belonging to Trichomonas tenax. Infection of HIV patients' oral cavity caused by T. tenax is rather related with inflammatory processes than with the immunosuppression of these patients but should be considered as a potential factor in pathogenesis of oral disorders in immunosuppressed patients.

AIDS-Related Opportunistic Infections↗