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At least 19 recordsLinked to original sources
PubMed2006

Medical topography.

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Disease Transmission, Infectious↗
PubMed2002

N2 and P3 components of event-related potential in first-episode schizophrenic patients: scalp topography, medication, and latency effects.

Auditory N2 and P3 components of event-related potentials were assessed in first-episode schizophrenic and normal control subjects (n=12/group). P3 amplitude was decreased in the patients most prominently over the frontal areas in contrast to a widespread P3 amplitude decrease reported in chronic schizophrenia. Moreover, frontal attenuation of P3 amplitude was greater in the non-medicated compared with medicated patients, a finding that suggests frontal areas are primarily affected at the onset of the first schizophrenic episode. Prolongation of N2 and P3 latencies was also observed in the patients, which indicates that stimulus classification and memory updating processes were slowed even in early stages of schizophrenia. These findings indicate that first-episode schizophrenic patients produce N2 and P3 abnormalities that are distinct from those in chronic patients, and that psychotropic medication can attenuate event-related potential effects in specific ways.

Acoustic Stimulation↗
PubMed2000

The role of local knowledge in medical practice: a trans-historical perspective.

This article explores the role of participant-observation and ethnographic writing in the shaping of medical practice since Hippocrates. Drawing on a range of historical sources and genres that include the 17th- and 18th-century medical topographies and medical geographies, 19th-century medical ethnography and folklore, and their marginal persistence into the 20th century in the form of Mexican pasante reports, I argue that these writings should not be approached as part of the history of anthropology, but as specifically medical genres related to medical practice. The abandonment of these ethnographic practices by modern biomedicine is, I conclude, a consequence of two related developments: the hegemony of clinical epistemology and the depersonalization and depoliticization of physicians' commitment to their patients.

Anthropology, Cultural↗
PubMed2000

Optic disk topography after medical treatment to reduce intraocular pressure.

PURPOSE: We examined changes in optic disk topography using confocal scanning laser ophthalmoscopy after reducing intraocular pressure with administration of latanoprost. METHODS: Twenty-nine patients with glaucoma or ocular hypertension were imaged using the Heidelberg Retina Tomograph before and after the administration of latanoprost to decrease intraocular pressure. Average time between pretreatment and posttreatment imaging was 2.7 +/- 1.8 weeks. Heidelberg Retina Tomograph software-measured parameters were mean height of contour, cup area, cup volume, mean cup depth, maximum cup depth, cup shape, rim area, rim volume, cup-to-disk ratio, and retinal nerve fiber thickness. RESULTS: Average intraocular pressure decreased significantly (mean +/- SD) by 7.2 +/- 5.4 mm Hg (25 +/- 16% decrease). No statistically significant changes in measured topographic parameters were found. When data from patients with decreases in intraocular pressure of 7 mm Hg or greater were analyzed separately (mean intraocular pressure decrease = 10.79 +/- 4.32 mm Hg, 36 +/- 8% decrease), cup area (P =.005), cup volume (P =. 002), and cup-to-disk ratio (P =.005) decreased significantly, and rim area (P =.005) increased significantly. Linear regression analysis of the data from all subjects showed that a change in intraocular pressure after latanoprost administration accounted for 12% or more of the variance in two measured topographic parameters (mean cup depth and cup shape). CONCLUSIONS: These results suggest that, in some patients, moderate decreases in intraocular pressure may affect disk topography, as measured by Heidelberg Retina Tomograph. Intraocular pressure should be considered when analyzing consecutive confocal scanning laser ophthalmoscopy images for glaucomatous progression.

Antihypertensive Agents↗
PubMed2002

The role of French-language contributors to the development of medical geography (1782-1933).

In the literature it is L. L. Finke's three volume work Versuch einer aligemeinen medicinisch-praktischen Geographie, 1792-1795, that is commonly cited as the first to use the term "medical geography". However, Rofort's investigations on the 18th and 19th century development of medical topography in France (1987, 1988) has revealed that a French physician, Dehorne, used the term a decade earlier, and in 1784 Dehorne suggested that a project be undertaken by the Royal Medical Society of Paris on a "Medical Geography of France". The proposal was debated in the Journal de Médecine Militaire in 1786. This correspondence probably is the earliest critique of the concept of medical geography. It was also the French who were the first to have entries on medical geography in dictionaries and encyclopedias. Dr. Jean-Noël Hallé wrote a lengthy piece conceptually placing medical geography as a foundation for medical hygienics in Encyclopédie Méthodique (1787, 1792). In 1817 Julien Virey wrote a 66 page entry on medical geography in the Dictionnaire des Sciences Médicales. Throughout the nineteenth century authors writing in the French language continued to make advances and in 1933 the French geographer Max Sorre suggested new directions for the field in the light of bacteriological discoveries and the re-orientation of medicine.

Dictionaries, Medical as Topic↗