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Results for “Tooth Replantation”

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At least 19 recordsLinked to original sources
PubMed1991

[Indices of hexosamine-containing biopolymers in experimental tooth replantation].

The experimental findings showed that the content of hexosamine-containing biopolymers, in periodontal tissue increased by 38.23 and 124% conformably over 14 days after replantation of 4 teeth of the dogs. The indices normalized in 28 days of the experiment. Investigated biochemical parameters in the root of replantation tooth, in osseus tissues of alveolus 2nd blood. Changed slightly in dynamics.

Alveolar Process↗
PubMedDate not supplied

[One-stage tooth replantation in acute inflammatory processes].

The authors have developed and tried a method for simultaneous teeth replantation with the use of a low-frequency ultrasound in patients with acute inflammatory processes. Teeth replantation was carried out in 50 patients, followed up for 1 month to 3 1/2 years. A combination of ultrasonic treatment of a replanted tooth and hole with periosteotomy and corticotomy rules out the development of postoperative complications, shortens the period of temporary disability in the patients with acute odontogenic inflammatory processes.

Acute Disease↗
PubMed1998

Osteointegration of a replanted tooth followed by RVG densitometry.

The frequency of dental traumas in children has been increasing. This work reviews a patient aged 9 who had the 2-day old fracture of the root of first permanent central incisor skewed palatinally 3 mm under the bone. The tooth was extracted, its canal filled with calcium hydroxide, and within less than 10 minutes the tooth was replanted and fixed by a metal splint. Daily follow-up did not show either pathological perioodontal changes or subjective pain symptoms. After 3 months the tissue density of both incisors was the same, i.e. the fractured tooth showed entire osteointegration.

Absorptiometry, Photon↗
PubMed2001

Alteration in the expression of heat shock protein (Hsp) 25-immunoreactivity in the dental pulp of rat molars following tooth replantation.

The regeneration process of dental pulp following tooth replantation in rat molars was investigated by immunocytochemistry for heat shock protein (Hsp) 25 and protein gene product 9.5 (PGP 9.5). In control teeth at postnatal 4 weeks, the odontoblasts showed intense Hsp 25-immunoreactivity in the coronal dental pulp, but little or no immunoreactivity in the root and floor pulp. In contrast, the Hsp 25-negative odontoblasts in the latter areas displayed immunoreactivity for PGP 9.5. Tooth replantation caused loss of Hsp 25- and PGP 9.5-immunoreactions in the dental pulp during postoperative days 1-3. At postoperative day 5, plump cells with clear nucleoli and several fine processes--presumably newly differentiated odontoblasts--at the pulp-dentin border became immunopositive for Hsp 25. These data suggest that the expression of Hsp 25- and PGP 9.5-immunoreactivity reflects the status of differentiation of the odontoblasts. Furthermore, some pulpal nerve fibers as well as the Schwann cells in the dental pulp, ordinarily negative in Hsp 25-immunoreaction, acquired their immunoreactivity by postoperative day 5, but lost it thereafter, suggesting the involvement of Hsp 25 in the regeneration of pulpal nerve fibers. In the case of bone-like tissue formation in the pulp space, on the other hand, no Hsp 25-immunoreactive odontoblasts were recognized in the pulp-dentin border. Thus, the alignment of Hsp 25-immunopositive odontoblasts along the pulp-dentin border indicates a decisive factor for inducing the reparative dentin formation after tooth replantation.

Animals↗
PubMed2000

[Complicated tooth replantation].

The materials and techniques for tooth replantation in presence of complications are discussed on the basis of recent advances in oral medicine and surgery and dentistry. The following complications are examined: mucous and cutaneous wounds, retention of teeth and foreign bodies, bony and radicular fractures with or without tissue loss, root drying, infection. Other problems are also discussed: replantation of deciduous teeth, endodontic therapy, stabilization of replanted teeth, application of orthodontic forces. Some technical principles are presented for a better management of various clinical situations. At last, interesting clinical cases are reported.

Adolescent↗
PubMed2006

Histochemical and immunocytochemical study of hard tissue formation in dental pulp during the healing process in rat molars after tooth replantation.

Dental pulp is assumed to possess the capacity to elaborate both bone and dentin matrix under the pathological conditions following tooth injury. This study was undertaken to clarify the mechanism inducing bone formation in the dental pulp by investigating the pulpal healing process, after tooth replantation, by micro-computed tomography (mu-CT), immunocytochemistry for heat-shock protein (HSP)-25 and cathepsin K (CK), and histochemistry for both alkaline phosphatase (ALP) and tartrate-resistant acid phosphatase (TRAP). Under deep anesthesia, the upper right first molar of 4-week-old Wistar rats was extracted and immediately repositioned in the original socket. In control teeth at this age, the periphery of the coronal dental pulp showed intense ALP-positive and HSP-25-positive reactions, whereas there were no TRAP-positive or CK-positive cells. Tooth replantation weakened or terminated ALP-positive and HSP-25-positive reactions in the pulp tissue at the initial stages. At 3-7 days after operation, the ALP-positive region recovered from the root apex to the coronal pulp followed by HSP-25-positive reactions in successful cases showing tertiary dentin formation. In other cases, TRAP-positive and CK-positive cells appeared in the pulp tissue of the replanted tooth at postoperative days 5-10 and remained associated with the bone tissue after 12-60 days. Immunoelectron microscopy clearly demonstrated that CK-positive osteoclast-lineage cells made contact with mesenchymal cells with prominent nucleoli and well-developed cell organelles. These data suggest that the appearance of TRAP-positive and CK-positive cells is involved in the induction of bone tissue formation in dental pulp.

Acid Phosphatase↗
PubMed1998

Responses of macrophage-associated antigen-expressing cells in the dental pulp of rat molars to experimental tooth replantation.

Bacterial infection of the dental pulp is a major hindrance to successful pulp regeneration after tooth replantation. This study examined how macrophages and class II molecule-expressing cells of the pulp respond to tooth replantation, on the hypothesis that they contribute to the defence and repair of the traumatized pulp. Upper right first molars of 5-week-old male Wistar rats were replanted immediately after extraction; contralateral untreated teeth served as controls. Pulpal cells expressing macrophage-associated antigens were immunohistochemically demonstrated at 0 h (immediately after the replantation) to 84 days postoperatively using antirat monoclonal antibodies OX6 (anti-class II molecules), ED1 (pan-macrophage antibody, reactive also with dendritic cells) and ED2 (anti-resident macrophages). Between 3 and 7 days postoperatively, ED1+ and OX6+ cells, but not ED2+ cells, were concentrated in areas of degeneration formed in the coronal pulp, and frequently showed a marked accumulation along the pulp-dentine border of the cuspal area. Confocal laser scanning microscopy revealed that some of the OX6+ cells with a dendritic profile extended several cytoplasmic processes into the dentinal tubules communicating with the enamel-free area at the tip of the cusp. From 14-84 days, approx. two-thirds of specimens exhibited pulp-tissue regeneration with increasing formation of reparative dentine. Following the formation of sound reparative dentine, cells positive to each antibody were distributed more centrally in the pulp than in the controls, and thus did not show any accumulation along the pulp-dentine border. However, in the other specimens where a bone-like hard tissue had formed in the pulp chamber, many ED1+ and OX6+ cells were still concentrated in the remaining pulp tissue and showed a marked accumulation along the pulp dentine border. Few ED2+ cells were observed in these specimens. These findings suggest that, following tooth replantation, exudative macrophages are actively engaged in eliminating dentinal tubule-derived infectious stimuli and that class II molecule-expressing cells, most probably containing dendritic cells, are positioned strategically at the outermost portion of the injured pulp to monitor incoming antigens. The intensity of the pulpal defence reaction may be dependent on the status of hard-tissue formation, which influences the amount of incoming antigens.

Animals↗
PubMed1996

[Experimental study on the healing of immediate replanted tooth after using exogenous fibronectin].

The purpose of this article is to study the effect on the healing of immediate replanted teeth after the biological characters of roots were changed by using exogenous fibronectin (Fn). Two adult rhesus monkeys were chosen in the experiment. Upper-incisors of each monkey were extracted. The teeth of experimental group were extracted the roots treated by 0.5 mg/ml Fn solution and replanted immediately. The roots of another animal were used as controls. After operations, the experimental specimens of 4 weeks and 8 weeks were examed histologically by light microscope and studied quantitatively by computer image analysis system. The results reveal that Fn can enhance periodontal healing by improving periodontal reattachment and reducing root resorption of replanted tooth. Fn has also the function to reduce inflammatory reactions significantly during the healing process.

Animals↗
PubMed1979

Eleven-year follow-up of tooth replantation.

An 11-year clinical and radiographic follow-up of an avulsed tooth, replanted within 15 minutes, has been presented. The periodontal membrane can be traced around the replanted central incisor, indicating the tooth is not ankylosed and is functionally attached. It is not anchored immutably to the bone. The tooth has responded dynamically to growth and development of the maxilla and now abuts and aligns well with the other teeth in the arch.

Adolescent↗
PubMed1992

Effect of stannous fluoride and tetracycline on periodontal repair after delayed tooth replantation in dogs.

Previous studies have indicated that inflammatory resorption and ankylosis, which are frequent sequela after delayed tooth replantation, can be greatly reduced by treating the root surface with 1% solutions of stannous fluoride and tetracycline. However, the SnF2 conditioning leaves a long-standing inflammatory reaction in the periodontal ligament. To examine whether a more dilute SnF2 solution would reduce postoperative inflammation without jeopardizing any beneficial effects, anterior teeth in three young adult beagles were extracted and allowed to air-dry for 45 min. They were then immersed in 0.1% SnF2 for 5 min, rinsed in saline, immersed in 1% doxycycline HCl for 5 min, rinsed, and replanted. Control teeth were air-dried and replanted without further treatment. Block biopsies were harvested after 4 wk of healing and processed for histometric analysis. In experimental teeth, 85% of the root surface area showed normal healing, compared to 33% in control teeth. Conversely, resorption and ankylosis were more frequent in controls than in experimental teeth. A persisting inflammatory reaction either adjacent to or at a distance from the root surface was seen in limited areas in both experimental and control teeth. Compared to preceding studies, the findings indicate that reducing the strength of the SnF2 solution from 1% to 0.1% may result in less persistent inflammation, at the cost, however, of less complete prevention of inflammatory resorption and ankylosis.

Alveolar Process↗
PubMed1999

A case report of a vital replanted tooth with unfavourable extra-alveolar condition: a 10-year follow-up.

This case report describes the survival of a maxillary left central incisor after an avulsion injury under unfavourable extra-alveolar condition, when the patient was 9 years old. At subsequent clinical follow-ups, the tooth maintained vitality 10 years after the injury. There was sign of gradual obliteration of the root canal space. Concomitantly, the replanted tooth manifested typical characteristics of ankylosis with minimally detectable resorption complication.

Adolescent↗
PubMed2004

Effect of recombinant human bone morphogenetic protein-12 (rhBMP-12) on regeneration of periodontal attachment following tooth replantation in dogs.

OBJECTIVES: Subcutaneous and intramuscular implants of bone morphogenetic protein-12 (BMP-12) have been shown to induce formation of tendon and ligament tissue. BMP-12 induced a new attachment with a distinct fibrocartilaginous zone at the tendon-bone interface in the rat tendon-bone attachment model. Surgical controls showed poor healing and failure to reform the appropriate tendon-bone attachment morphologically. Application of recombinant human BMP-12 (rhBMP-12) to periodontal defects suggests that rhBMP-12 has the potential to support regeneration of the periodontal ligament (PDL). The objective of this pilot study was to evaluate this effect of rhBMP-12 in a tooth replantation model. METHODS: Six, young adult, male Hound Labrador mongrel dogs were used. Maxillary and/or mandibular incisor and premolar teeth were extracted and the PDL was either left "intact" or removed by root planing. rhBMP-12 (1.0 mg/ml) or a buffer control was topically applied to teeth with "intact" PDL in contralateral jaw quadrants in each of 3 animals. The teeth were immersed in 1.0 ml of the rhBMP-12 or the buffer solution for 10 min and then replanted. The remaining three animals received rhBMP-12 (1.0 mg/ml) and the buffer control in a similar fashion applied to teeth instrumented to remove the PDL and cementum, and surface demineralized with citric acid. The animals were euthanized at 8 weeks postsurgery and block sections were collected and processed for histopathologic analysis. RESULTS: No dramatic differences were found between teeth receiving topical rhBMP-12 and the buffer control. Application of rhBMP-12 did not have an apparent effect on new cementum and PDL formation in the tooth replantation model. Moreover, application of rhBMP-12 did not increase nor did it decrease the apparent presence and extent of ankylosis along the root surface compared to the control. CONCLUSIONS: The observations from this study do not support the use of topical rhBMP-12 to support the reestablishment of the PDL including regeneration of cementum and functionally oriented fibers, and to prevent ankylosis and root resorption following replantation of teeth.

Animals↗
PubMed1967

Tooth replantation.

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Tooth Replantation↗