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Results for “Therapeutic Irrigation”

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At least 19 recordsLinked to original sources
PubMed1980

Dissolution of cystine stones by irrigated tiopronin solution.

A new method involving the introduction of tiopronin solution directly into the renal pelvis or bladder has been developed for the treatment of cystine stones. Therapeutic irrigation by tiopronin solution was done in 4 cases of residual cystine kidney stones using a nephrostomy tube, and in an infant with bladder cystine stones using a Foley 3-way catheter. In every case all of the cystine stones were dissolved completely. During the course of the treatment no abnormality was noted on blood, liver function or immunological tests. Neither have there been any negative side effects, such as eruption, anorexia, nausea, diarrhea or general fatigue. The significance of this irrigation process is that whereas nephrectomy, heminephrectomy or nephrolithotomy was necessary previously to remove kidney cystine stones, now only pyelolithotomy and nephrostomy tube insertion are necessary. Furthermore, an operation is unnecessary in cases of bladder cystine stone dissolution by tiopronin irrigation.

Adolescent↗
PubMed1982

Whole bowel irrigation in pediatric patients.

Whole bowel irrigation was used in 24 patients ages 8 to 17 yr, mean 13 yr, in preparation for colonoscopy (18), colon surgery (2), therapeutic irrigation for treatment of drug overdose (2), and constipation (2). An average of 9 liters warm, normal saline with added KCL (5 mEq/liter) was infused through a nasogastric tube over a period of 7 +/- 2 hr (mean +/- SD). This resulted in a weight gain of 2% and a mild hyperchloremia. The vital signs remained stable and there were no complications. The colonic preparation was complete in 10, adequate in 8 and unsatisfactory in 2. The irrigation was effective in the treatment of overdose ingestion and constipation. It is concluded that whole bowel irrigation is a satisfactory method of colonic preparation of pediatric patients.

Adolescent↗
PubMed2005

[Intracanal aspiration technique for root canal irrigation: evaluation of smear layer removal].

A new irrigation technique (intracanal aspiration technique, IAT) was developed to minimize the extrusion of root canal irrigant. Fifteen instrumented canals of extracted canines were divided into one control and four experimental groups of 3 teeth each. Each root was fixed in a case and surrounded with colored saline agar to measure the meter value of the Root ZX and to evaluate the extrusion of the irrigant. In control teeth, no irrigation was performed. In Groups 1 and 2, the root canal was irrigated using IAT with an aspiration needle placed 2 or 3 mm short of the apex. In Groups 3 and 4, the root canal was irrigated in a conventional manner with a washing needle placed 2 or 3 mm short of the apex. The file folder of a Root ZX was attached to the aspiration needle in Groups 1 and 2, and to a washing needle in Groups 3 and 4. Each canal was irrigated with 9 ml of 14% EDTA solution and 6 ml of 6% NaClO in experimental groups, and the meter value of the Root ZX during irrigation was recorded. After the irrigation, cleanliness of the canal was evaluated using a SEM and extrusion of NaClO by discoloration of the agar. Irrigation using IAT was more effective for removing smear layer compared to the conventional method and extrusion of the irrigant was minimized. In addition, the Root ZX measurement during IAT could monitor the extent of the irrigant in the apical canal.

Dental Pulp Cavity↗
PubMed1978

[Effect of the propellants O2 and CO2 on the efficacy of oral irrigation].

The therapeutical results obtained with oral irrigations when O2 or CO2 was used as a propellant air compared with those achieved with compressed air. The assessment of the therapeutical success was based on the periodontal disease index according to Kötzschke and the exsudate heights according to Egelberg. A significant improvement in the periodontal condition was stated in all three groups of patients. Though only the exsudate values for the O2 group were significantly better than those for the compressed air group, being the only difference between the groups which was significant, the greater efficiency of the O2 and CO2 application (compared to compressed air application) is, nevertheless, obvious and interpretable. The therapeutical results obtained permit the statement that a technically perfect device and the further increase of the partial pressure of O2 or CO2 in the irrigation fluid will lead to even better therapeutical results, for which purpose the suggestions given should be considered in establishing the indication. The favourable results achieved with compressed air testify to the beneficial action of each irrigation or spray treatment.

Aerosols↗
PubMed1984

The disc dressing for local irrigation of experimental burn wounds.

The newly designed disc dressing permits the surface of experimental burn wounds to be irrigated with liquid therapeutic agents without the need for frequent dressing changes. This approach is simple to handle, reduces the risk of trauma or contamination of the wound, and is not time consuming.

Animals↗
PubMed1976

The protective role of intraperitoneal antibiotic irrigation in contaminated penetrating wounds of the cecum.

Neomycin (500 mg.), polymyxin (500,000 U.), and bacitracin (50,000 U.) in one liter of saline, used as an abdominal irrigation solution, protects dogs against intraperitoneal infection and wound infections and markedly curtails adhesion formation after peritoneal contamination with cecal contents. Dogs treated with topical antibiotics after cecal puncture and local contamination were almost identical to control dogs without contamination. Equal volumes of saline irrigation offered no therapeutic advantage despite the theoretical benefit of diluting the bacterial and chemical challenge. Reported results are statistically significant (rho less than or equal to 0.05).

Animals↗
PubMed1984

Whole-gut irrigation as antiendotoxinaemic therapy in inflammatory bowel disease.

Marked endotoxaemia was found in 12 patients suffering from severe relapse of chronic inflammatory bowel disease. These patients did not respond satisfactorily to conservative treatment. Whole gut irrigation was employed to reduce drastically the absorbable endotoxin pool in the gut. Following the lavage the condition of all the patients thus treated improved. Plasma endotoxins dropped rapidly, serum iron increased, and in 7 febrile patients body temperature normalized. The results obtained suggest a beneficial use of whole gut irrigation as a therapeutic means in endotoxaemia associated with inflammatory bowel disease.

Adult↗
PubMed1992

Prophylactic and therapeutic carboprost tromethamine bladder irrigation in rats with cyclophosphamide-induced hemorrhagic cystitis.

Recently, prostaglandins have been shown to be effective agents for the treatment of cyclophosphamide-induced hemorrhagic cystitis. Among the prostaglandins studied is carboprost tromethamine, a PGF2a analog. To determine the effectiveness of carboprost tromethamine therapy on the urothelium, we induced hemorrhagic cystitis in 81 rats. These were divided into two treatment arms. One arm was treated prophylactically at the time of cyclophosphamide injection, and the other started treatment only after hemorrhagic cystitis was established. Animals were divided equally into groups receiving 0, 0.4, 0.8, and 1.6 mg.% carboprost tromethamine in 0.9% normal saline by continuous bladder irrigation. All bladders were examined grossly for edema and hemorrhage, then histologically for mucosal ulceration, congestion, and perivascular hemorrhage. Results from the prophylactic arm, as compared to those for controls, revealed that all groups except those treated only with 0.9% normal saline had a lower incidence of hemorrhagic cystitis (p less than 0.05). In the established hemorrhagic cystitis arm, the group treated with 1.6 mg.% carboprost tromethamine showed the best response (p less than 0.05), whereas the group treated with 0.9% normal saline showed the poorest response. This study reveals that hemorrhagic cystitis in the rat model may be prevented by prophylactic continuous bladder irrigation with carboprost tromethamine, whereas established hemorrhagic cystitis may be treated effectively with intravesical instillation of carboprost tromethamine. Although the mechanism of action of this prostaglandin on the urothelium is unknown, it appears grossly and histologically to decrease ulceration, perivascular hemorrhage, and congestion in the mucosa and submucosa.

Animals↗