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At least 19 recordsLinked to original sources
PubMedDate not supplied

Breaking strength of native and sutured trachea. An experimental study on sheep trachea.

Tracheal anastomoses are, even more so than other sutures, often only possible to prepare under tension and thus in danger of breakage. No information is available regarding native tracheae and freshly sutured tracheae. For this reason, our objective was to examine the tensile strength of native tracheae and compare it with freshly sutured specimens. Fresh tracheae were collected from the local slaughterhouse within 30 min of slaughter. With the help of a suitable holding device, 24 fresh tracheae were mounted on a material testing machine and stretched to breaking point, during which the force and distance required were recorded. The same study was carried out on each 10 freshly anastomosed tracheae using three different suturing techniques. The mean value of the maximum force required for native tracheae was 198 N. With continuous suturing (polypropylene), a mean value of 171 N was attained, and with single interrupted suturing (polydioxanone and polyglactin 910), 123 N, respectively, 108 N. Differences between the groups proved to be highly significant. With respect to the mechanical strain from traction, the continuous suture proved to be statistically identical to native tracheae, whereas single interrupted sutures revealed a considerably lower stability under burden. Therefore, the continuous suture is of advantage in respect of the mechanical strain from traction and the suture protection of tracheal anastomoses. Further studies with differing survival times in vivo with this method provide insight into the stability of tracheal anastomoses during the healing process.

Anastomosis, Surgical↗
PubMed2003

Raillietiella trachea n. sp., a pentastomid from the trachea of an oriental white-backed vulture Gyps bengalensis taken in Pakistan, with speculation about its life-cycle.

A cephalobaenid pentastomid, Raillietiella trachea n. sp., from the trachea of a fledgling oriental white-backed vulture Gyps bengalensis taken in Punjab Province, Pakistan, is described. This is the first record of a pentastomid from a fully terrestrial bird. Overall, gross morphology was typical of Raillietiella Sambon, 1910 in most respects. However, the hooks of R. trachea were of equal size, whereas in other members of the genus anterior hooks are smaller than the posterior hooks. The diagnosis of R. trachea was made on the basis of four near-patent females, all of which contained relatively few eggs (c.570), all at the same stage of maturity. Comparison with the only other genus known to infect birds (two species of Reighardia Ward, 1899 from the air-sacs of marine birds) revealed striking parallels in this aspect of the functional anatomy of the female reproductive tract. As far as we know, this mode of egg-production is not found in other raillietiellids. Extrapolating primarily from the experimental life-cycle studies of Reighardia sternae (Diesing, 1864) Ward, 1899, we surmise that the life-cycle of R. trachea has to be direct and that parasite behaviour is an integral part of parasite transmission. The evidence suggests that transmission is from vulture-to-vulture, per os.

Animals↗
PubMed1990

[Effects of As2O3, MNNG and B(a)P on epithelia of human fetal tracheae and rat tracheae in organ culture].

The effects of As2O3, MNNG and B(a)P on epithelia of human fetal tracheae and rat tracheae in organ culture were studied. In human fetal trachea, a small dose of arsenic (1 mumol As) induced hyperplasia of the epithelium; 3-9 mumol As induced hyperplasia and cellular atypia in the epithelium, and hyperplasia and squamous metaplasia in the adenoepithelium. Similar effects were not observed in rat tracheae. MNNG and B(a)P induced hyperplasia, squamous metaplasia and dysplasia in human fetal tracheal and rat tracheal epithelia respectively, and MNNG also induced hyperplasia and squamous metaplasia in human fetal tracheal adenoepithelium. The data suggest that 1) arsenic may be carcinogenic to the human respiratory tract but not to the rat; and 2) human tissues in organ culture are very useful for detecting carcinogens and for studying carcinogenesis.

Animals↗
PubMed1987

[Development of the larynx and trachea following division of the cricoid cartilage and segmental resection of the trachea in the growth stage. An animal experiment study].

Laminotomy as described by Réthi, and segmental tracheal resection with end-to-end anastomosis have proved useful in the adult for the treatment of stenoses of the larynx. In children, the question arises why these may interfere with the growth of the larynx and trachea. A vertical split of the cricoid cartilage followed by stabilization of the larynx by the temporary introduction of a Montgomery silicone T-tube was carried out on four kittens aged four to six weeks. A segmental tracheal resection with end-to-end anastomosis was performed on other animals of the same age. When the animals had stopped growing, the larynx and trachea were investigated both endoscopically and histologically. Following laminotomy the larynx underwent remodelling, resulting in an oval shape, the lumen being wide and the function of the vocal cords normal. Following segmental resection of the trachea, a circular stenosis was found, as a result of irregular growth of the sutured tracheal cartilages. In none of the animals, however were either functional disorders or respiratory distress to be observed. Thus, laminotomy or segmental resection of the trachea can be employed during the formative years without fear of clinically relevant growth disorders.

Age Factors↗
PubMed1979

Surgical treatment of adenoid cystic carcinoma of the left main bronchus and trachea by left pneumonectomy, resection of 7.5 cm of trachea, and direct reanastomosis of right lung.

A 23-year-old woman, who had suffered recurrent acute bronchitis, dyspnoea, and stridor, was found to have a tracheal stenosis and complete left main bronchus obstruction. Biopsy of the tumour showed an adenoid cystic carcinoma. After pneumonectomy the trachea was closed through tumour tissue. Two weeks later a right thoracotomy showed that a tumour had invaded the trachea from the carina up to 6 cm and the right stem bronchus for 1 cm. Under extracorporeal circulation 7.5 cm of the trachea and right bronchus were resected. A direct tracheal anastomosis was easy to perform. Spontaneous respiration with efficient coughing returned after five days. Unfortunately, one month later, high fever caused by a lung abscess developed, which provoked a massive haemoptysis with fatal outcome.

Adult↗
PubMed1992

[Reconstruction of trachea, carina and bronchus for tumors of the trachea, carina and lung].

This paper reports on 70 patients with tumors of the trachea, bronchus and lung treated by reconstruction of the trachea, carina and the main bronchus (21 cases) and sleeve lobectomy (49 cases). Postoperatively, 2 patients died of tracheo-innominate artery fistula and 2 developed empyema which was healed. There was no mortality in the sleeve lobectomy patients. The 3- and 5-year survival rates of the cancer patients treated by reconstruction of trachea, carina and main bronchus were 54.5%(6/11) and 33.3%(3/9), respectively. The 3- and 5-year survival rates of lung cancer patients treated by sleeve lobectomy were 46.6% (14/30) and 33.3% (7/21), respectively.

Adenocarcinoma↗
PubMed1981

Primary malignant lymphoma of the trachea. Report of a case successfully treated by primary end-to-end anastomosis after circumferential resection of the trachea.

A 67-year-old Japanese man with exertional dyspnea was found by laminagraphy to have tracheal obstruction. The stricture was localized at the cervical and mediastinal trachea and was 5.0 cm long on an x-ray film. Eight tracheal rings were successfully resected and the ends of the trachea were anastomosed. The lumen of the removed trachea was narrowed by intramural and intraluminal polypoid growth originating from the tracheal wall. Histologically, the tumor was diagnosed as a mixed type of malignant lymphoma. The patient had serum hepatitis postoperatively, but now he is living normally without any difficulty in respiration. No signs of recurrence have been seen in the 5 years, 4 months since the operation. From this experience, the rarity and the possibility of curative operation of this tumor are discussed.

Aged↗
PubMed1975

"Saber-Sheath" Trachea: A Clinical and Functional Study of Marked Coronal Narrowing of the Intrathoracic Trachea.

Data are presented from thirteen patients with marked coronal narrowing of the intrathoracic trachea associated with widening of the corresponding sagittal diameter. The term "saber-sheath" trachea describes this deformity which can simulate a mediastinal mass. The absence of mediastinal masses and the presence of obstructive pulmonary abnormalities in each patient, either as a clinical diagnosis (11 of 13), functional abnormality (10 of 11) or both (8 of 11), suggest that the "saber-sheath" trachea may be a useful sign of chronic obstructive pulmonary disease.

Aged↗
PubMed1988

Trachea-noise biofeedback in asthma: a comparison of the effect of trachea-noise biofeedback, a bronchodilator, and no treatment on the rate of recovery from exercise- and eucapnic hyperventilation-induced asthma.

We review some of the evidence that supports the existence of psychosomatic triggers to bronchospasm in asthmatics, and hypothesize that it may also be possible to consciously reverse bronchospasm using trachea-noise biofeedback. We precipitated significant levels of bronchospasm in 16 asthmatics using exercise or eucapnic-hyperventilation challenges on five occasions, and administered four different treatments and a no-treatment control. The treatments were trachea-noise biofeedback (TNBF), wrong-information TNBF, an inhaled adrenergic bronchodilator, and a placebo inhaler, all given double blind. Half of the subjects had 3 training days in the use of the TNBF device before study. Our results show that TNBF, in the trained subjects only, is associated with a detectable, but not statistically significant, increase in the rate of recovery from bronchospasm over that found with no treatment. We conclude that, although asthmatics seem to have a strong ability to consciously induce bronchospasm, conscious reversal of a full asthma attack using TNBF is limited. Despite contrary conclusions by other investigators, we believe that this study demonstrated little TNBF-assisted recovery from bronchospasm. We suggest that this is because its effect may be inhibited by humoral mechanisms that sustain the attack, but we believe further work is required to support this.

Adult↗
PubMed2004

Anesthetic management of a patient undergoing segmental resection of trachea with an endotracheal neurofibroma and nearly total occlusion of trachea.

We report a case of endotracheal (ET) neurofibroma with resultant severe airway obstruction undergoing segmental resection of the trachea. After the extracorporeal membrane oxygenation system (ECMO) was set up handily for use and comprehensive monitoring system was established, ET intubation under fiberoptic bronchoscopy (FOB) was performed under mild sedation. Surgery and anesthesia proceeded uneventfully and she was discharged uneventfully. Thorough preoperative evaluation, comprehensively anesthetic planning, FOB-assisted ET intubation before induction of anesthesia were mandatory to achieve a safe and delicate anesthesia for such a patient. In critical situation, conduction of anesthesia after establishment of ECMO support would be another choice.

Adult↗
PubMed1984

Contraction of guinea pig trachea with antibodies to guinea pig IgE. An in vitro model for asthma. II. Reactivity of guinea pig tracheas to anti IgG1 and anti IgG2 in comparison with anti IgE.

Although relatively small quantities of antibody to guinea pig IgE were shown to contract isolated guinea pig trachea in vitro, relatively large quantities of anti IgG1 were required to elicit similar responses. Under similar conditions, anti IgG2 did not provoke contraction. Following intravenous injection of these antisera into normal guinea pigs, anaphylaxis or asthma could be only provoked by anti IgE.

Animals↗