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Results for “TABES DORSALIS”

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At least 19 recordsLinked to original sources

Rapidly progressive tabes dorsalis associated with selective IgA deficiency.

Tabes dorsalis is uncommon and progresses slowly from infection to clinical manifestation. We report a rare case of rapidly progressive tabes dorsalis associated with selective IgA deficiency (sIgAD). A 28-year-old man was hospitalized with lightning back pain, nausea, and bladder bowel dysfunction. Serum and cerebrospinal fluid (CSF) revealed high titers of Treponema pallidum antibody, and the serum IgA level was less than 5 mg/dl. Thl-dominant cytokine expression was observed, as is usually seen in neurosyphilis. He was treated with Ceftriaxone and CSF pleocytosis disappeared. We postulate sIgAD influenced the atypical rapid clinical course of tabes dorsalis in this patient.

Adult↗

Neurosyphilis presenting as tabes dorsalis in a HIV carrier.

Tabes dorsalis associated with human immunodeficiency virus (HIV) infection is extremely rare. This is a report of a 36-year-old male who had developed unsteady gait for 4 months. Tabes dorsalis was diagnosed by clinical manifestation and CSF examination. HIV antibody was proved by Western blotting. HIV accelerates and alters the natural course of treponemal infection by changing the immunological response of the lues.

Adult↗

Abnormal chemoreceptor response to hypoxia in patients with tabes dorsalis.

Nine patients with tabes dorsalis and one patient with diabetic autonomic neuropathy were subjected to hypoxia to test the integrity of their carotid chemoreceptors. Ventilation and pulse rate changes were monitored and compared with those of a group of normal subjects of comparable age and sex. Four patients had a completely negative response to hypoxia, and the changes in ventilation in the group of patients as a whole were significantly less than in the control subjects. The results indicate that some patients with autonomic denervation are unable to adjust their respiratory system in response to hypoxia.

Aged↗

Tabes dorsalis: electrodiagnostic features.

Electrodiagnostic data have not been previously reported in tabes dorsalis. A patient with tabes dorsalis is described whose nerve conduction studies and median nerve somatosensory evoked responses (SEPs) were normal. H-reflexes were absent. SEPs of the tibial nerve suggested posterior column dysfunction. These electrodiagnostic findings correlate precisely with the known pathology of tabes dorsalis.

Afferent Pathways↗

Tibial nerve SEPs localized the lesion site in a patient with early tabes dorsalis.

There is controversy regarding the initial pathology of tabes dorsalis. In a patient with early tabes dorsalis, tibial nerve somatosensory evoked potentials elicited normal P15, a delayed traveling peak in the lumbar bipolar leads, and absent subsequent components. Based on the comparison with normative data and stimulation at different intensities, the authors conclude that only the slower conducting antidromic motor volleys are preserved, whereas the dorsal root is damaged at its distal end.

Adult↗

[A case of tabes dorsalis observed in an HTLV-1 carrier].

We report a case of a 53-year-old female HTLV-1 carrier with tabes dorsalis. In addition to typical symptoms of tabes dorsalis, she presented HTLV-1 associated myelopathy (HAM) like clinical features such as sensory disturbance with thoracic sensory levels and bladder disturbance (pollakiuria). Although penicillin treatment did not improve in her neurological symptoms, steroid therapy was effective especially in HAM like symptoms. The CSF neopterin level was markedly decreased after steroid therapy, indicating that inflammation in the spinal cord was settled down after treatment. Our case suggests that CNS infection like tabes dorsalis may be modified by HTLV-1 infection and then present some atypical clinical features based upon altered immunological aspects of HTLV-1 carriers.

Carrier State↗

Suspicion of somatoform disorder in undiagnosed tabes dorsalis.

We present a case of tabes dorsalis, which consisted of intermittent, sharp pains and diffuse neurological abnormalities, and was initially considered to be a somatoform disorder. The unusual behavioural presentations of neurosyphilis may lead to premature psychiatric diagnoses. It is thus important that psychiatric consultants be aware of the myriad manifestations of the disease.

Diagnosis, Differential↗

[Changes in the femoral neck in tabes dorsalis. Case report].

The authors analyze diagnostic and therapeutic problems in fractures associated with tabes dorsalis. In the foreground of the clinical picture are in the majority neurological symptoms. The first symptoms develop 15 years after the primary infection. The laboratory results are not decisive for the diagnosis. Previously treatment of these fractures was conservative in rare instances arthrodesis of the affected joint was performed. In the case-history the authors submit new therapeutic possibilities in fractures of the neck of the femur associated with tabes dorsalis, using total endoprostheses of the hip joint. The authors mention also possible complications. The subjective evaluation by the patient is, however, very favourable.

Arthropathy, Neurogenic↗

Disorders of micturition in tabes dorsalis.

The aim of this study was to determine whether the disorders of micturition that occur in patients with tabes dorsalis can be attributed exclusively to disturbed bladder sensation, as has been previously suggested. Urodynamic studies were performed in 8 patients with tabes dorsalis who had no obvious organic obstructive urological disease. The results indicated that not only disturbed bladder sensation but also suprasacral and/or sacral lesions innervating the detrusor could be responsible for voiding dysfunction in such patients.

Adult↗

[A case of severe rarefaction osteopathy associated with tabes dorsalis].

The authors report the case of a 63 years old man who presented 13 years after a diagnosis of a tabes dorsalis, stress fractures of the lower limbs and Charcot's joints (knees). 7 years later, he had multiple stress fractures of the sacrum and pelvis and of the ribs following a minor trauma. Laboratory investigations revealed a major osteoporosis probably related to the neurochirurgical complications of the tabes dorsalis.

Fractures, Stress↗

'Oblongata' crises in tabes dorsalis.

A patient in the pre-ataxic stage of tabes dorsalis suffered from gastric crises, but in addition had numerous episodes of apnoea and coma which in the older literature have been described as 'oblongata crises'--the presumption being that the crises are due to a brain stem disturbance.

Abdomen↗