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At least 19 recordsLinked to original sources

Reasons for rejecting potential donors from a sperm bank program.

PURPOSE: Recruiting donors to a sperm bank program is difficult and slow because of high dropout rates and high rejection rates. The profile of successful and unsuccessful donors was determined at our sperm bank. METHODS: A total of 199 men was screened from 1986 to 1994 in the anonymous sperm bank donor programs; 174 (87%) men dropped out or did not meet minimum guidelines. The study included 25 accepted donors and 20 rejected men (of 52 rejected donors, only 20 donors who came for two consecutive semen analyses were selected). Sperm quality variables and demographic data were compared between the groups. RESULTS: Accepted donors had significantly better semen quality in motility, velocity, linearity, and ALH than did rejected donors (P < 0.01). More rejected donors than accepted donors were single (P < 0.01). A higher percentage of accepted donors consumed caffeine (P < 0.001), and they were more likely to have college degrees (P < 0.03). CONCLUSIONS: These results indicate that loss of interest and poor semen quality were the major reasons for rejection of donors in our anonymous donor sperm bank program.

Adolescent↗

[The Munich cryopreserved sperm bank--intermediate 1974-1986 evaluation].

The storage of spermatozoa from tumour patients in sperm banks is an important medical task. As a result of improved treatment strategies the survival rate, particularly in patients with testicular tumours and Hodgkin's disease, is excellent if the diagnosis is made early. However, the necessary therapeutic measures often lead to the mutilation of reproductive function. At the Department of Dermatology at the University of Munich a sperm bank has been in existence since 1974; most of the patients who consult the sperm bank are men with testicular tumours. A synopsis of the last 12 years provides information about the patients, indications for storage, the method of preservation used and the fate of the cryopreserved samples used for insemination. To guarantee that optimal results are achieved, cryopreserved sperm samples should only be used by gynaecologists who are particularly experienced in the treatment of sterility.

Adolescent↗

Sperm banking and patients with cancer. Issues concerning patients and healthcare professionals.

In 1994, approximately 52,000 new cancers will have occurred in patients < or = 34 years of age. Reported survival rates for tumors common to males in this age group are promising and are expected to improve. Chemotherapy treatment may produce infertility, and without appropriate intervention, the aspiration of producing offspring may never be realized. Semen cryopreservation (sperm banking) may be offered to male patients with cancer as an intervention to circumvent loss of procreation ability resulting from chemotherapy-induced infertility. Oncology nurses can discuss infertility and sperm banking with patients at the most opportune time, before initiation of chemotherapy. Considerable debate exists among health-care professionals regarding the practicality and usage of sperm banking for young adult male patients with cancer being treated with chemotherapy. In addition, health-care professionals may be uncomfortable discussing issues of a sexual nature with patients. Staff nurses administering chemotherapy to young adult males need to work toward improving their knowledge about the effects of cancer and cancer treatment on reproduction. Improved knowledge will reinforce the importance of offering sperm banking to circumvent treatment-induced infertility.

Adult↗

Poor semen quality from patients with malignancies does not rule out sperm banking.

Cancer therapy can further impair the already poor semen quality in cancer patients. This study evaluated the prefreeze and postthaw semen quality before treatment of patients with malignancies to examine the rationale for sperm banking for these men. Records of nine patients with different malignant tumors, who had been referred for sperm cryopreservation between 1982 and 1997, were reviewed and the results were compared with those of 50 normal healthy donors. Patients did not differ from donors in age, ejaculate volume, or duration of sexual abstinence. The total motile sperm count (median and interquartile range) was significantly different between patients and donors for prefreeze specimens (P = 0.026) and postthaw specimens (P = 0.008). Also, the percent motility was significantly lower in the patients as compared with the donors in prefreeze (P = 0.035) and postthaw specimens (P = 0.005). The percentage change in motility after thawing was also larger for patient samples (-54% versus -47%, P = 0.39). Other sperm motion characteristics did not significantly differ between the two groups except for postthaw curvilinear velocity (P = 0.01). This study concludes that fresh and frozen thawed semen from patients with malignant tumors is poor in quality but is still adequate for assisted reproductive techniques. As cancer therapy may further impair semen quality, patients should be offered the chance to bank sperm before undergoing cancer therapy.

Adolescent↗

Causes of donor rejection in a sperm banking program.

During a 2-year period, 93 men between the ages of 18 and 46 years were screened for sperm donation using a three-stage protocol. Thirty (32%) applicants became active donors. Eighty-five percent of the semen specimens from these men were successfully frozen, quarantined, and released for insemination. The three-stage protocol successfully eliminated most uncommitted or unqualified applicants in an efficient, cost-effective manner. Sperm cryopreservation increased the rejection of otherwise acceptable donors by 27%.

Adolescent↗

Clinical aspects of sperm bank.

The ability to preserve human sperm by cryogenic methods has been developed and successfully applied to reproductive biology. Some of the advantages include 1) availability of sperm for heterologous (donor) insemination, 2) accumulation of multiple oligospermic specimens for homologous (husband) insemination, 3) preservation of sperm prior to vasectomy, 4) collection and preservation of sperm from men who face permanent injury to spermatogenesis through an operation, chemotherapy or radiation, 5) to obviate the potential genetic danger of man's exposure to environmental pollutants such as radiation and 6) availability of husband's sperm at ovulation time.

California↗

Sperm banking.

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Adolescent↗