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At least 19 recordsLinked to original sources
PubMedDate not supplied

The advantage of modular software design in computerized ECG analysis.

In the early 1970s, modular software design was advocated as a means to obtain better structured and more reliable software systems. Such a modular approach was also introduced for computerized ECG processing in 1972. The TNO Modular ECG/VCG interpretation system was developed along these lines. During the last decade, the algorithms of this system were thoroughly improved and evaluated. This resulted in 1983 in a new version of this system named MEANS (Modular ECG ANalysis System). This paper outlines the ideas of the modular approach as they were originally defined in 1972 and developed over the years. The usefulness and advantages of these ideas will be discussed based on 12 years of experience. It appeared that modularity is the ideal approach to the development and maintenance of complex systems such as for ECG/VCG interpretation.

Computers↗
PubMed1992

[A software design for standard grayscale printout of China-made automatic static quantitative TBC visual field analyser].

A method of "TBC GRAPH" software design for standard grayscale printout of TBC static quantitative perimetry is introduced. The software is operated in IBM PC/XT or PC/AT compatible computer, using Chinese Character Disk Operating System (CCDOS) which has widespread users in China. Symbols were established by using CCDOS word--make function, and sectoral as well as symbolic matrix were made, which realized the standard grayscale printout. The software is recommended for use in ophthalmic clinic and education.

Humans↗
PubMed1987

Computer assisted psychiatric diagnosis: experiments in software design.

The process of psychiatric diagnosis involves the real-time utilization of large amounts of knowledge to maintain and test multiple hypotheses. Therefore, the development of an on-line computerized assistant that can aid a clinician performing psychiatric diagnoses presents challenging problems in data-base organization and retrieval. We have developed the DUNE (Diagnostic Understanding of Natural Events) system architecture that organizes the knowledge around processing structures. The system was designed as a shell for expert-systems that aid diagnoses and assessment tasks in ill-structured domains in general. These domains have previously proven unfeasible for traditional expert-systems such as rule based systems. Currently, DUNE contains sufficient knowledge to aid the diagnosis of anxiety and affective disorders. Among DUNE's advantages: a large degree of tolerance to clinician errors, and flexibility at run time. In this paper, we discuss the general specifications for a program that can aid psychiatric diagnoses, and then describe DUNE and its capabilities.

Adolescent↗
PubMed1986

Software design for an inexpensive, practical, microcomputer-based DNA cytometry system.

Recent advances in digital electronics have made it possible to put together videophotometry systems capable of practical DNA ploidy measurements at a relatively modest cost. Such a system, based upon the IBM PC microcomputer and other "off-the-shelf" components, is now operational in our laboratory. This paper discusses the design considerations that went into the development of the software for this system. It examines the choices, constraints and tradeoffs involved in such a software engineering project and considers the practical implementation of image processing algorithms and a user-friendly interface. An overview is given of the modular, menu-driven software through which the system is controlled, along with a description of normal operational flow.

Cell Nucleus↗
PubMed1992

[Use of a computer-controlled servo system to produce "ephysiological" contraction of isolated rat papillary muscle].

A computer-controlled servo system consisting of an ergometer with a force-displacement dual mode transducer, a Z-80 single-board microcomputer and a designed software was constructed. This servo system can be used to generate physiological contraction in isolated rat papillary muscle, in which the muscle went through a complete 4-phase cycle of force and length changes, similar to those undergone by muscle fibers in the beating heart during the cardiac cycle. This system is being used to investigate the tension-length relation and the network of isolated myocardium as well as the end-systolic tension-length relation and the force-velocity relation simultaneously.

Animals↗
PubMed1992

VA's Integrated Imaging System on three platforms.

The DHCP Integrated Imaging System provides users with integrated patient data including text, image and graphics data. This system has been transferred from its original two screen DOS-based MUMPS platform to an X window workstation and a Microsoft Windows-based workstation. There are differences between these various platforms that impact on software design and on software development strategy. Data structures and conventions were used to isolate hardware, operating system, imaging software, and user-interface differences between platforms in the implementation of functionality for text and image display and interaction. The use of an object-oriented approach greatly increased system portability.

Computer Graphics↗
PubMed1988

Pharmacokinetic estimation for therapeutic dosage regimens (PETDR)--a software program designed to determine intravenous drug dosage regimens for veterinary applications.

Pharmacokinetic estimation for therapeutic dosage regimens (PETDR) is a soft-ware program used to design individualized intravenous dosage regimens, determine concentration-time profiles, predict serum concentrations at a specific time after intravenous dosing and predict the time after the last dose to achieve a specified concentration of drug. The reference pharmacokinetic parameters may be based on an individual animal's pharmacokinetic disposition of drug or on FARAD (Food Animal Residue Avoidance Databank) mean population kinetic parameters. An individual animal's kinetic parameters may be input for predetermined analysis or the program can calculate these values by input of raw serum concentration-time data. The program allows the user to specify certain parameters of the dosage regimen, then calculates the other parameters (given desired maximum and minimum serum concentrations, dose and interval are calculated; given desired maximum serum concentration and interval, dose is calculated, etc.). Given the kinetic parameters, the dose and dosing interval, the program calculates and plots the serum concentration-time profile of the drug for that animal. The time and the number of doses to reach steady state can be calculated as well as the determination of loading dose. The percentage of the time of a dosing interval at steady state that the serum concentration is above a specific minimum inhibitory concentration (MIC) allows evaluation of efficacy of an antimicrobial regimen. Similarly, the time to reach a specific concentration (e.g. residue tolerance) or the MIC of a drug can be calculated. Legal tissue tolerances can be accessed from FARAD to aid in predicting for what period of time illegal residues will remain in the animal.(ABSTRACT TRUNCATED AT 250 WORDS)

Animals↗
PubMed1988

Quality controlling interpretive reporting systems in clinical medicine--a changing responsibility.

This paper presents some observations on a number of topics which affect the quality of computer software and includes: current trends in software design, current levels of responsibilities for the various parties involved in bringing automation to clinical medicine, why software development is so difficult to quality control, and certain characteristics of system development which contribute most to the construction of inaccurate models.

Humans↗
PubMed1988

Development of stereological analysis software for the calculation of volume, number and surface density.

COSAS, an acronym for COmputerized Stereological Analysis System, is software designed to facilitate the process of quantitative morphological analysis. It is a flexible, reliable, and easy to use software system which provides the biologist with a simple means for performing stereological analysis. It provides for estimation of volume and surface density and allows for direct calculation of diameter information from planimetric data. The latter capability is unique to COSAS and provides the ability to calculate longest and shortest diameters for convex profiles, enabling calculation of number density. Access to all intermediate calculations is possible, so the process of transformation of raw data into the stereological descriptors can be completely exposed. This serves two purposes: (1) it provides a means for tracing results; (2) the intermediate values can be utilized independently. This system was used to analyze peroxisomes in tissues from patients with Zellweger's disease and neonatal-onset adrenoleukodystrophy. The system was also used to facilitate an immunocytochemical analysis of cytochrome P450 topology in the endoplasmic reticulum membrane.

Algorithms↗
PubMed1992

A manufacturing system for contoured foam cushions.

The design, application and evaluation of a specialized, personal computer-based manufacturing system for contouring foam cushions is presented. The topics discussed include both the hardware configuration and the software design. The target applications of this device are local or centralized fabrication of custom-contoured seat cushions. Although the technologies used for the development and implementation of this system are not new, using a personal-computer-based (PC) controller in place of a stand-alone numerically controlled (NC) motion controller significantly reduced the cost associated with this component. Further reductions in cost resulted from an optimization of the mechanical configuration for the dedicated task of carving foam cushions.

Computer-Aided Design↗
PubMed1992

Analysis of beat-to-beat cardiovascular hemodynamic variables obtained from long-term biotelemetry.

Manual methods of large volume data storage, retrieval, and analysis are difficult, time consuming, and present numerous opportunities for calculation errors. We have designed and implemented a comprehensive computer-based system for performing these functions. Development of this system was necessary since left ventricular (LV) blood pressure and two regional LV wall thickness measurements were obtained during long-term extracorporeal biotelemetry of miniswine for 24-h periods. During a single recording period over 100,000 individual cardiac cycles were recorded on analog tape and later analysed for determination of global myocardial oxygen demand and regional myocardial function. In addition, custom designed software was developed to determine the extent and duration of myocardial dysfunction. Batch file commands enabled the customized software to operate without prompting by the user thus optimizing the time usage of the computer, and the computer based data acquisition and analysis system. Although this system was designed specifically for analysing cardiovascular hemodynamic variables, it is flexible and can be applied to other experimental applications.

Analog-Digital Conversion↗
PubMedDate not supplied

X-File: a program for maintaining a radiographic teaching file.

Software designed for entry, retrieval, and maintenance of radiographic case-file data on a microcomputer offers considerable help in maintaining such records in a radiology department. The case files are based on the Index for Roentgen Diagnoses, published by the AmericanCollege of Radiology. The terms and code numbers of the index are included in the software, so that the user need only enter the diagnostic term desired; the code numbers and exact terminology are assigned automatically. The software is written for an IBM-compatible microcomputer. Residents and staff radiologists have been using the program for the past two years to store and find both confirmed cases and other interesting cases. The system's capacity exceeds 70,000 entries on a 20-megabyte had disk. The program has five features not found in previous similar programs and not attainable with manual methods.

Hospital Information Systems↗