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Results for “Soft Tissue Neoplasms”

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At least 19 recordsLinked to original sources
PubMed1979

[Clinical TNM classification of malignant soft tissue neoplasms].

A project for the classification of malignant soft tissue tumors according to the TNM system is suggested for a wide discussion. The classification takes into account the effect of some leading factors (histological type of a tumor, its size, the state of regional lymph nodes, the degree of the adjacent tissues infiltration) on the prognosis of this affection. Tumors staging is done through combining various grades of T, N, M criteria.

Humans↗
PubMed1979

[Biometric studies in the cytological diagnosis of soft tissue tumors].

Introducing of quantitative signs (the number of cells on the given area, size of cells, nuclei, optic and spectral characteristics) makes the cytologic diagnosis much more objective. Karyometric studies conducted by the author (the determination of nuclei volume) on cytological smears, obtained from 16 patients with soft tissue tumors, indicated some difference in nuclei size of various histotypes. The studies have evidenced that the method of karyometry associated with cytophotometry will offer the pre-conditions for using karyometry in the practice of pathocytologists and facilitate the finding of algorithms for computing analysis of soft tissue neoplasms.

Cell Nucleus↗
PubMed1979

[Differential diagnosis of nodular fasciitis].

A clinico-morphological analysis of 32 observations of nodular fascitis enabled the recognition of a number of signs (a rapid growth, polymorphism of the cellular and structural content, infiltration of the adjacent tissues), which might simulate a malignant character of the lesion. Whereas the analysis also revealed some distinguishing features of soft tissue neoplasms resembling nodular fascitis.

Adolescent↗
PubMed1979

[Cryotherapy of benign neoplasms of the soft tissues in the maxillofacial area].

In the light of the relevant literature and of personal studies, the author deals with the possibilities of treating benign neoformations in the maxillofacial region by cryotherapy. The results are discussed from the aspects of cryophysical and cryobiological prerequisites. The extension in depth of the changes is the decisive criterion for cold application.

Cryosurgery↗
PubMed1979

Computed tomography of paranasal sinus tumors.

Thirty-two patients with histologically proved malignant disease involving the paranasal sinuses were studied by CT. The radiological features of tumor were sinus opacification, a soft-tissue mass, bone erosion and/or displacement, sclerosis, and new-bone formation. Measurements of tissue densities were not helpful in distinguishing tumor from benign disease. Significantly greater tumor extent was demonstrated by CT than by conventional methods in 15 patients; the additional tumor most commonly involved the pterygoid region or orbit. The clinical importance of various directions of tumor spread is emphasized.

Adolescent↗
PubMed1978

Detection of subcutaneous metastases by computed tomography.

Subcutaneous fat provides excellent contrast for water density tissue. Five patients with subcutaneous metastases visualized on computed tomography (CT) scans are presented. In some cases, CT proved to be the optimal diagnostic modality for visualizing these lesions and documenting their response to therapy.

Adult↗
PubMed1979

Atypical lipoma, atypical intramuscular lipoma, and well differentiated retroperitoneal liposarcoma: a reappraisal of 30 cases formerly classified as well differentiated liposarcoma.

Thirty cases formerly diagnosed as Grade I lipogenic liposarcoma (well differentiated liposarcoma) were reviewed. The basic histologic pattern in all was that of adult fat modified by the presence of cells with enlarged, hyperchromatic nuclei; in most cases there was also a component of myxoid and/or fibrous tissue. The length of follow-up ranged from two to 30 years. Nine of the tumors were located in the subcutaneous layer. None of these recurred after excision, not even those which were simply "shelled out," and none metastasized. The term "atypical lipoma" is proposed for this group. Thirteen were located within or between muscles of the limbs, limb girdles, and head and neck. Nine of these recurred at least one, but there were no metastases and no deaths due to tumor. These were designated "atypical intramuscular lipoma." The remaining eight originated in the retroperitoneum. Although none of these patients developed metastases, five suffered inoperable recurrence and three died as a result of the neoplasm. It is suggested that the term "well differentiated retroperitoneal liposarcoma" be retained for cases of this type.

Adult↗
PubMed1978

Fibrous histiocytoma metastatic to the orbit.

The term fibrous histiocytoma encompasses a heterogenous group of tumors believed to have a common origin in the histiocyte. These tumors demonstrate a wide histopathologic spectrum ranging from a predominantly cellular to a predominantly fibrous pattern. No clinical or histological criteria have been identified that can predict malignant behavior. Although generally characterized by local recurrence, a metastatic potential does exist. Fibrous histiocytoma of the thigh metastasized to the orbit.

Diagnosis, Differential↗
PubMed1977

Malignant fibrous histiocytoma. An electron microscopic study.

Sixteen cases of malignant fibrous histiocytoma are presented. Electron microscopy of 15 cases demonstrated fibroblast-like and mononuclear and multinucleated histiocyte-like cells. A small capillary was at the center of all storiform areas examined. Ultrastructural examination can be diagnostically useful within the context of a narrow differential diagnosis by conventional microscopy and the ability, by electron microscopy, to eliminate other mesenchymal cell types. In 13 cases, follow-up information was available from 18 months to 9 years following histological diagnosis. Five patients are alive and 8 patients have died, including two non-tumor related deaths. In 3 cases follow-up was less than 4 months. The biologic behavior of the tumor in this series was generally not related to histopathological parameters. The issue of histogenesis is largely unresolvable. Ultrastructural studies of various types of fibrous histiocytomas, suggesting cells of origin other than histiocytes, give credence to the concept that the histiocyte may represent a morphologic state of a given mesenchymal cell rather than a particular cell type.

Aged↗
PubMed1979

Malignant neoplasms in Saudi Arabia.

In a sample of 1000 consecutive malignant neoplasms in Saudis resident in the Western Region of Saudi Arabia, malignant lymphoma was the commonest of the life-threatening malignancies. The differences between malignant lymphoma in this sample and Western series include the greater frequency of lymphoma; the tendency for reticulum cell and poorly differentiated lymphomas to present as abdominal lesions; the earlier peak of prevalence of Hodgkin's disease, and the dissimilar proportions of its subtypes. The distribution of cancers in the gastrointestinal tract in our sample is almost the reverse of that encountered in the West in that cancer of the mouth and esophagus were more common than cancer of the lower intestinal tract. Lung cancer was relatively uncommon. The smoking habit is not so prevalent in Saudi Arabia as in the West and there is a need to maintain this situation by discouraging smoking. Cancer of the breast was by far the commonest major malignancy in the female, although most Saudi women have their first child early in their reproductive life. Skin cancers proved to be the most prevalent malignancy, and of these squamous cell carcinoma was the most common. The biases that affect studies such as ours in Saudi Arabia are stressed.

Adolescent↗
PubMedDate not supplied

Rhabdomyosarcoma of the head and neck: diagnosis and management.

Rhabdomyosarcoma represents the most common soft-tissue neoplasm of the head and neck found in children. The tumor is most commonly seen in Caucasian children under the age of 12, usually presenting as a painless mass. Distant metastases are frequently present, especially in regional lymph nodes, lung, and bone marrow. All patients suspected of having this disorder should have a thorough examination of the head and neck, as well as a complete radiographic evaluation of the primary region. Histologic disagnosis should be made as rapidly as possible. Once this has been accomplished, a thorough search for metastatic disease can be undertaken. Therapy must be individualized, and a team approach is advocated. The roles of surgery, radiation therapy, and chemotherapy are discussed. A staging system and a treatment-therapy plan are outlined.

Child↗
PubMed1978

Adriamycin and other anthracycline antibiotics under study in the United States.

Adriamycin is now firmly established as a drug with a very broad spectrum of antitumor activity. It has had a major impact on the therapy of sarcomas. The dose response effect in this tumor is steep and combinations which compromise the dose of adriamycin too greatly are showing inferior results. In lung and breast cancer combinations with adriamycin have been extensively tried. The FAC Regimen in breast cancer has given excellent results at the M.D. Anderson Hospital. The inclusion of adriamycin in combinations has had an impact in the poor prognosis histologies of non-Hodgkin's lymphomas. The CHOP regimen is one of the best developed to date for diffuse histiocytic lymphomas. In the leukemias adriamycin is probably equivalent to daunorubicin which has been more extensively used in this country. A new analog called Rubidazone has shown good activity in AML with a smooth induction and its incorporation into combination with Ara-C, vincristine and prednisone in a regimen called ROAP is being investigated. Adriamycin in complex with DNA has been clinically evaluated, but at this time, no advantage for this approach can be demonstrated.

Antibiotics, Antineoplastic↗
PubMed1979

Congenital fibrosarcoma metastatic to the choroid.

A 2 1/2-year-old boy developed a choroidal metastasis from a congenital fibrosarcoma of the lower left limb that had been amputated shortly after birth. To our knowledge this is the first reported case of a congenital fibrosarcoma that metastasized to the choroid.

Amputation, Surgical↗