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At least 19 recordsLinked to original sources

[Fiber endoscopy and radiology in stomach ulcer, stomach neoplasms and hiatal hernia: questions, timing and value].

In 306 patients, fiberpanendoscopy and radiology were performed within a time interval of 7 days or less. In 196 cases, radiology was performed before endoscopy and in 110 cases after endoscopy. In cases with histologically unproven divergent findings, follow-up studies were performed. In the diagnosis of gastric ulcer and gastric cancer, endoscopy with biopsy was more accurate than radiology. In the diagnosis of hiatal hernia, radiology was more accurate. Important additional findings difficult or impossible to observe with endoscopy were present in 36% of the radiological examinations. Thus, the first examination should be endoscopy when ulcer or carcinoma is suspected. In patients with uncharacteristic epigastric symptoms, radiology should be performed first.

Duodenum↗

[Complicated form of chronic stomach ulcer].

Stomach ulcer is one of the most important problems of gastroenterology. Complicated, often recurring, giant and refractory stomach ulcers are most complex in the pathogenetic and treatment regard. The chronic and often recurring course of the disease, high percent of complications including such severe ones as perforation and bleeding, malignization, penetration and stenosis quite often result in a partial or complete disability in patients. As is well known, it is generally the most active and capable part of population that suffers from this disease.

Adult↗

[Stomach ulcer and stomach cancer].

About 5--10% of the gastric carcinomas develop from a gastric ulcer (ulcerocancer). This process, however, is, referred to gastric ulcers, too rare to indicate a prophylactic resection of the stomach on account of the danger of the development of cancer. Careful diagnostics and following control with X-ray examination and gastroscopy are, however, necessary in every gastric ulcer. The retrogression of the complaints neither proves healing of the ulcer nor benignity of the ulcer. Compared with the ulcerocarcinoma the differential diagnosis of the gastric ulcer is easy when locally advanced, patelliform carcinomas are in question. It is difficult in small carcinomas and especially in the carcinoma of the mucous membrane of type III. Individual radiologic and endoscopic signs and especially their combination are useful for the differentiation, but they may be misleading. A carcinomatous ulcer may radiologically and endoscopically look like a peptic ulcer and may apparently also fully heal. Therefore, a certain differential diagnosis is only possible with the help of an aimed biopsy of the stomach or the cytodiagnostics. The two methods serve further propagation. They should be used in every case, when an apparantly benign ulcer does not reveal a clear retrogression under effective treatment with carbenoxolone within four weeks. The examination of the gastric juice may be used for the differential diagnosis.

Carbenoxolone↗

[The dependence of the formation of stress stomach ulcers on the function of the hypothalamo-hypophyseal-adrenal cortical system].

The effect of supraphysiological doses of corticosteroids on mucosal ulceration of stomach was studied in rats. Cortisol (30 mg/100 g) blocked the PACS. During the PACS block, ulcerogenic properties of stressor increased. This effect was reduced by subsequent corticosterone replacement therapy. The new concept of supraphysiological doses of corticosteroids effect is discussed. The stomach ulceration seems to result from the corticosteroid insufficiency.

Adrenal Cortex Hormones↗

[Stomach ulcers in newborn swine].

Stomach ulcers were established in sucking pigs, aged 1-3 days, on a pig-breeding farm. Thirty-two out of 40 pigs (spontaneously affected) of 5 primiparous sows died for 24 hours. Necropsy revealed ulcers on the mucous membrane of the stomach, varying in size and development of morphologic lesions. Histologic investigations were also carried out. Hemolytic Escherichia coli organisms were isolated form the same pigs, and were studied for pathogenicity and toxigenicity. An analysis was made of the etiologic factors contributive of stomach ulcers in newborn pigs.

Animals↗