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At least 19 recordsLinked to original sources

[Unusual tumor: liposarcoma of the spermatic cord].

Spermatic cord liposarcoma is a rare tumour, as only 60 cases have been reported in the literature. They represent 7% of all malignant spermatic cord tumours. The authors report a new case of spermatic cord liposarcoma unusual by its inflammatory and fibrotic features, occurring in an 83-year-old man in poor general health. Treatment consists of surgical resection as widely as possible. Adjuvant radiotherapy is sometimes effective on local recurrences. Despite the slow rate of progression of this tumour, prolonged surveillance is required due to the high risk of late recurrence.

Aged↗

[Intravaginal perinatal torsion of the spermatic cord].

Spermatic cord torsion is an urologic emergency that requires urgent evaluation and possibly emergency surgical management. In a neonate it occurs during testicular descent and is usually due to an extravaginal torsion, where the testis and sperinatic cord twist. We present a case of intravaginal testicular torsion in a neonate. In this situation, as the anomalous implant of the tunica vaginalis can occur bilaterally, it is important to fix the contralateral testis in order to prevent late torsion of this gonad.

English Abstract↗

Spermatic cord block and manual reduction: primary treatment for spermatic cord torsion.

A total of 16 consecutive cases of acute torsion of the spermatic cord less than 24 hours in duration are presented. All patients were diagnosed and treated initially by spermatic cord blockade and attempted manual detorsion. Of the 16 patients 15 underwent successful detorsion under local anesthesia. All patients underwent subsequent bilateral orchiopexy. Testicular salvage was 93 per cent in those patients who underwent successful detorsion by manipulation.

Adult↗

Familial torsion of the spermatic cord.

Familial spermatic cord torsion is rare. We present the fifth recorded family with this condition. Due to awareness of the condition and its consequences on the part of the family there was minimal delay in presentation and early testicular salvage occurred in all 4 patients.

Adolescent↗

[Spermatic cord torsion].

Spermatic cord torsion happens rather frequently in young men. It must be discovered early on, to allow for the possibility of removal by surgery. It appears from recently written medical articles that the endocrine function of the testis is protected following several hours of torsion and the risk of immunological damage to the contralateral testis is subsequently reduced.

Adolescent↗

Tubular embryonal remnants in the human spermatic cord.

The spermatic cords (SCs) obtained from: (a) autopsies of 67 adults and 50 children; (b) 3 fetuses; (c) 12 surgical specimens from 9 adults and 3 children with testicular tumors, and (d) 26 surgical specimens (14 adults and 12 children) with diagnosis of SC cysts, were studied by light microscopy. The histological study revealed the occurrence of tubular embryonal remnants (TERs) in 19 autopsied adults, 14 autopsied children, 3 fetuses, 2 surgical specimens (1 adult and 1 child) owing to testicular tumors, and 6 surgical specimens with diagnosis of SC cysts. The TERs were found in the low, middle or high thirds of the SC and consisted of a cuboidal or columnar, often ciliated epithelium surrounded by connective tissue. In the 3 fetuses and in 3 autopsied children renal glomeruli were found in close relation with the TERs. In 2 cases of SCs showing cysts and TERs both structures contained spermatozoa. The histological pattern of the TERs suggest that they are wolffian derivatives which might give rise to SC cysts.

Adult↗

Angioarchitecture of the human spermatic cord.

Human spermatic cords were investigated by means of cast preparations, light-microscopic examination and computer-aided 3-dimensional reconstructions from serial sections of paraffin-embedded material. After leaving the testis, the testicular veins formed two principal groups co-existing side by side. Numerous veno-venous anastomoses could be observed within each individual group, whereas only a few mutual intergroup anastomoses were found. The testicular artery ran within one group but showed no close topographical relationship to the other group. Light microscopy of the serial sections revealed that the group of veins with no close topographical relationship to the testicular artery ran at a distance of several centimeters embedded within fatty tissue. With the help of computer-aided 3-dimensional reconstructions, a spatial picture of the vascular organization was obtained. These results allowed the following classification of the veins of the pampiniform plexus. Group-I veins formed a tight plexus around the testicular artery by means of veno-venous anastomoses. Group-II veins formed veno-venous anastomoses between each other and ran over at a sizeable distance embedded in fatty tissue but showed no close topographical relationship to the testicular artery. Group-III vessels formed veno-venous anastomoses between group-I and group-II. Group IV veins formed arterio-venous anastomoses with the testicular artery. Based on the differences in wall structure and diameter, a subclassification in group-I and group-II was undertaken. This organization of the veins of the human pampiniform plexus should further the understanding of physiological processes, such as the transfer of hormones and other substances from the veins to the testicular artery and vice versa. It should also facilitate the tracing of the veins during antegrade sclerosing.

Adult↗

Is ipsilateral testis mandatory for the occurrence of contralateral intratesticular biochemical changes indicative of hypoxia after unilateral spermatic cord torsion?

Experimental unilateral spermatic cord torsion has been shown to induce both ipsilateral and contralateral intratesticular biochemical changes indicative of hypoxia. An experimental study was conducted to see whether the presence of the ipsilateral testicular tissue is necessary for the occurrence of the biochemical changes in the contralateral testis. Male, adult, albino rats were divided into four groups each containing 10 rats. One group served to determine basal values of biochemical parameters indicative of tissue hypoxia, another group was subjected to unilateral spermatic cord torsion in the presence of ipsilateral testis; a further group was subjected to unilateral spermatic cord torsion after ipsilateral subepididymal orchiectomy, and the last group underwent unilateral subepididymal orchiectomy alone as control. Lactic acid, hypoxanthine and lipid peroxidation product levels which are biochemical indicators of tissue hypoxia were determined in testicular tissues and kidneys. All three parameters increased significantly in contralateral testes but not in kidneys after unilateral spermatic cord torsion both when the ipsilateral testis was present and absent (p < 0.05). It is concluded that the ipsilateral testis does not play a role in transmitting these contralateral changes after unilateral spermatic cord torsion. Impulse-triggering contralateral changes may arise from spermatic vessels or nerves.

Animals↗

An adult patient with a mixed germ cell tumor of the spermatic cord.

Tumors of the spermatic cord are very rare, and approximately one half of all primary spermatic cord tumors are malignant. We report the presentation and treatment of an adult (36-year-old) patient with a mixed germ cell tumor that originated in the spermatic cord. No similar cases of mixed tumors of the spermatic cord in adults have been reported.

Adult↗

Primary lymphoma of spermatic cord.

Primary lymphomas of spermatic cord are extremely rare. In a review of the world medical literature, until now, only fourteen cases of spermatic cord lymphoma have been reported, and, furthermore, they have a poor prognosis even in patients with stage I disease. Herein, we report a new case of primary non-Hodgkin's lymphoma of the spermatic cord. In August, 1993, 76-year-old man visited an urological hospital with a compaint of a right intrascoral mass, and underwent orchiectomy. Macroscopically no invasive lesion in the testis was observed, and the tumorous lesion was restricted to the epididymis. The histopathological study indicated that he suffered from primary malignant lymphoma of the spermatic cord (B-cell, diffuse medium-sized cell type). As radiographic investigations showed no other invasive lesion, the patient was diagnosed to be in stage IE. He was followed only with clinical observation, and, in August, 1996, relapsed with extensive disease in the abdoninal cavity, and was transferred to our hospital. Fourty months after the orchiectomy, he died of progression of disease irrespective of the salvage radio-chemotherapies given to him.

Aged↗

[Utility of pre-operative imaging diagnosis in spermatic cord liposarcoma].

A case of spermatic cord liposarcoma was revealed by imaging diagnosis. The patient was a 59-year-old male, who consulted our clinic with the complaint of painless right scrotal swelling on June 30, 1989. One year earlier, he noticed this swelling, which was slow growing little by little. Palpation revealed a movable mass in right scrotum, 7 x 3 x 3 cm in size and separated from the right testis. Scintigraphy could not show RI accumulation and ultrasonography showed a capsulated homogeneous mass. Computed tomography (CT) and magnetic resonance imaging (MRI) showed capsulated fat-like almost homogeneous mass, which enclosed the right spermatic cord. This mass was suspected of spermatic cord lipoma or liposarcoma and was removed with radical orchiectomy. The weight of the mass was 246 g. This mass had a bunch of grape appearance and consisted of several masses of various sizes surrounding the spermatic cord, and could be separated from the right epididymis and testis. Histological examination revealed well differentiated liposarcoma and lipoma. Spermatic cord liposarcoma is very rare and this preoperative diagnosis is very difficult. Imaging diagnosis, such as CT, MRI may help our preoperative diagnosis.

Genital Neoplasms, Male↗

Giant malignant mesenchymoma of the spermatic cord with bidirectional differentiation.

BACKGROUND: Spermatic cord neoplasms are a rare tumor entity and, moreover, of benign behavior. Malignant tumors of the spermatic cord are mostly of mesenchymal origin. We present the unusual case of a giant malignant mesenchymoma of the spermatic cord with bidirectional differentiation into a liposarcoma and a leiomyosarcoma. CASE REPORT: A 84-year-old male patient presented with a scrotal mass on the left side which was observed growing since 1 year and misdiagnosed as scrotal hernia or testicular hydrocele. Ultrasound and computed tomography demonstrated a solid tumor suggesting a spermatic cord tumor. The patient underwent hemiscrotectomy, and the histological examination of the 2,500-gram specimen revealed a malignant mesenchymoma originating from the spermatic cord with two distinct histopathological compartments of liposarcoma and leiomyosarcoma. Because an adjuvant therapy protocol is of questionable effect and because of the patient's age no further therapy was applied. The patient was closely followed and is now, 5 years after surgery, still free of disease. CONCLUSION: Even in older patients, scrotal masses should be considered malignant tumors as long as no benign diagnosis has been proven. Although malignant mesenchymomas are rare tumors with poor prognosis, in selected cases even large tumor masses, as presented, can be cured by surgery.

Aged↗

Mesotheliomas of spermatic cord.

Mesotheliomas of the spermatic cord are exceedingly rare and scarcely mentioned in the urologic literature. An additional case of spermatic cord mesothelioma is presented and the literature reviewed.

Adult↗

Giant liposarcoma of the spermatic cord.

Liposarcoma of the spermatic cord is rare and easily masquerades as a more common benign neoplasm of the spermatic cord. If neglected, these malignancies may grow to tremendous size and become formidable management problems. The treatment of this malignancy is orchiectomy and en bloc removal of the tumor. More radical operative therapy has not generally proved beneficial. Adjunctive therapy may be helpful in selected cases.

Genital Neoplasms, Male↗

Quantitative evaluation of testicular biopsies from men with unilateral torsion of spermatic cord.

Torsion of the spermatic cord is not uncommon among young men. Various abnormalities in the histology of the contralateral testis have been reported due to unilateral torsion of the spermatic cord. We quantitatively estimated the germ cells from three groups of men: normal individual (Group I), men with unilateral torsion of short duration (Group II), and men with unilateral torsion of long duration or some other condition such as varicocele or intermittent torsion to the contralateral testis (Group III). No significant difference in the number of spermatogonia, spermatocytes, and spermatids of Groups I and II patients was observed. This observation indicates that there was no pre-existing morphophysiologic defect in the testis of Group II patients. Severe damage in the contralateral testis was noted in Group III patients. This indicates that if a damaged testis is retained in the body for a long time, the contralateral testis may be affected. Contralateral testis may also be affected by intermittent torsion or varicocele.

Adolescent↗

Liposarcoma of the spermatic cord.

A case of spermatic cord liposarcoma is reported in a 40-year-old man. The clinical presentation, pathogenesis and role of sonography in pre-operative diagnosis is reviewed. The role of radical orchiectomy, retroperitoneal lymph node dissection, radiation therapy and chemotherapy in treatment of spermatic cord liposarcomas is discussed.

Adult↗