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At least 19 recordsLinked to original sources

Usefulness of vascular examinations in diagnosis and treatment of the face-skull neoplasms.

Arteriography of external carotid artery and sporadically orbitophlebography were performed in 52 patients of both sexes, aged 10-74 years. Indications for arteriography and orbitography stemmed from cases in which routine clinical-radiological examinations failed to determine the extent of neoplastic changes. The technique of transdermic puncture of the common carotid artery of the supraorbital vein was applied in the studies. Uropolin 75% was used as control material. The studies confirmed usefulness of arteriography both in the diagnosis and surgical treatment of neoplasms of the jaws as well as the face facilitating the determination of topography of the tumor and the direction of growth.

Adolescent↗

[Surgical approaches to the skull base neoplasms].

OBJECTIVE: To discuss the best surgical approach to the skull base neoplasms. METHODS: Retrospective analysis the 79 skull base neoplasms cases treated with surgical resection in Qilu hospital of Shandong university from 1992 to 2002. Eleven surgical approaches including midfacial degloving, frontal coronal discission, nasal eversion, maxillary swing, partial maxillary resection, total resection of orbit, mandibular swing, combination of front, temple, preauricular, post aureum, neck, and transoral approaches were used to resect the tumor which involved fossae pterygopalatine, paranasal sinuses, nasopharynx, antero, meso and posterobasilar region, lobi frontalis and lobi temporalis of cerebrum. RESULTS: Seventy-nine skull base neoplasms were totally removed and no one died from the operation. Although 5 cases complicated with cerebrospinal fluid leak and all recovered within 1 week, no serious cranium-cerebrum complication occurred. In 29 patients with benign tumor including 11 cases of meningioma, 3 cases of chondroma, 1 case of hemangio-meningioma, 1 case of cavernous hemangioma, 2 cases of osteodysplasia fibromas, 9 cases of neurofibroma, 1 case of glomus jugular tumor, 1 case of neurilemmoma, 19 have survived over 5 years and the longest one has survived over 8 years. For 50 patients with malignant tumor including 3 cases of well-differentiated squamous cell carcinoma, 17 cases of moderately differentiated squamous cell carcinoma, 11 cases of poorly differentiated squamous cell carcinoma, 1 case of undifferentiated carcinoma, 2 cases of chondrosarcoma, 5 cases of canceration of papilloma, 2 cases of adenocarcinoma, 1 case of esthesioneuroblastoma, 2 cases of malignant fibrohistiocytoma, 1 case of fibrosarcoma, 2 cases of malignant mixed tumour, 3 cases of sarcoma survival rates of 3 and 5 years were 59.2% (29/49), 38.5% (10/26) respectively. CONCLUSION: In order to resect the tumor completely and reduce the complication and malformation as far as possible, different surgical approaches must be designed according to the pathological changes characters and involved area,and the surgeon should select the shortest approach, avoid to damage the important neurovascular structure, and resect the tumor through the natural anatomy space by the shelter incision.

Adult↗

Education and information needs identified by patients and key family members prior to surgery for a skull base neoplasm: implications for practice.

Many patients with extensive skull base neoplasms poorly understand the nature of their problems. Therefore, education of patients and family members is an important component of care. Research has established the benefits of pre-operative education for other types of surgery and information seeking as an important method of coping. Yet in 184 references on skull base surgery (1996-1999), no case-based or research data that examined education and information needs prior to hospitalization for surgery was found. The investigators present findings from Phase 1 of a descriptive research study designed to determine the education and information needs perceived by patients and family members at their initial visit to the neurosurgeon and on admission to hospital. Data was collected, using interviews and a questionnaire, from 18 patients with skull base neoplasms and 15 key family members. The study findings provide insight into the experience of patients and families during a time period (prehospitalization) that has not been explored. Results indicate that key education needs of participants are related to the brain tumour and surgery. Findings reveal patient participants in contrast to family members had little in the way of information needs. Underlying and impacting the education and information needs is the theme of 'Hearing the News'. Relevance of the results to nursing practice in the pre-operative phase is addressed.

Adult↗

[Surgical approaches to the skull and near skull base neoplasms].

OBJECTIVE: To seek for the best surgical approaches to the skull and near-skull base neoplasms. METHOD: 161 patients with skull or near-skull base tumors were surgically treated. The surgical approaches were craniofacial approach in 6 cases, total maxillectomy or/with orbital exenteration in 5 cases, lateral rhinotomy in 7 cases, frontorbital approach in 1 cases, maxillary swing or extended maxillary swing approach in 21 cases, mandibular swing approach in 30 cases, cervical approach in 48 cases, postaurical large C incision approach in 19 cases, transparotid approach in 8 cases, transoral approach in 6 cases, temporofrontal approach in 8 cases, subtemporal preauricular approach in 2 cases. RESULT: Of the 98 benign tumors cases, 2 recurred postoperatively. Of the 63 malignant tumors, 1 case had cerebrospinal fluid leakage and died of intracranial infection 1.5 months postoperatively. In the follow up period, the longest one survival was over 8 years, and 10 over 5 years, 19 over 3 years, 16 over 2 years, 16 over 1 year. Survival rates of 3 and 5 years were 59.18% and 38.46% respectively. CONCLUSION: According to the site, range and pathology of the skull base neoplasmas, surgical approaches were designed and selected rationally and the effects better.

Adolescent↗

Radiology of skull base neoplasms.

Computed tomography (CT) and magnetic resonance (MR) imaging are used routinely to stage skull base neoplasms preoperatively, define the extent of the tumor, identify perineural spread, plan surgery and radiation therapy, and evaluate the postoperative patient. Arteriography and interventional radiology also play a role in the identification and treatment of certain skull base neoplasms, particularly juvenile nasopharyngeal angiofibromas and paragangliomas. The skull base can be divided into three parts: anterior, central, and posterior. Pathology differs in each region, and CT and MR imaging often demonstrate characteristic imaging features suggestive of diagnosis.

Humans↗

[Tumor of the skull-report on 119 patients].

OBJECTIVE: To study the pathologic type, clinical manifestations and treatment of skull neoplasms. METHODS: A series of 119 patients with skull neoplasm were analyzed retrospectively with respect of clinical manifestations, radiologic features, treatment and prognosis. RESULTS: 122 operations were done with 3 patients being operated twice. Complete resection was done 75 times, subtotal resection 24 times, partial resection 22 times and biopsy only once. Gross type: exophytic 43(36.1%), endophytic 27(22.7%) and mixed type 49 (41.2%). Among the 85 patients followed, 78.6% have recovered and are living well, 16.6% of patients are self-caring, 2 need others' help and 2 have died. CONCLUSION: Most skull neoplasms require neurosurgical intervention. Surgical excision is able to confirm the diagnosis, slow down the progression of neurologic dysfunction, prolong the patients' lives and improve the cosmetic results.

Adolescent↗

Reconstruction of skull base defects after minimally invasive endoscopic resection of anterior skull base neoplasms.

BACKGROUND: The endoscopic resection of the cribriform plate during minimally invasive endoscopic resection (MIER) of the anterior skull base neoplasms may result in large anterior skull base defects. The objective of this study is to describe techniques for the management of skull base defects after MIER. METHODS: Retrospective analysis was performed on patients undergoing MIER and skull base reconstruction between April 2000 and August 2005. RESULTS: Fourteen patients underwent endoscopic resection of anterior skull base tumors and reconstruction during the study period. The mean age was 57.4 years (range, 26-84 years). The sex distribution was eight men and six women. The specific indications for resection included 11 malignant and 3 benign neoplasms. Ten patients received adjuvant therapy, and in two instances this occurred before surgery. In all instances, the dura was exposed; however, only 10 cerebrospinal fluid (CSF) leaks were encountered intraoperatively. Reconstruction of the skull base was successfully performed, most commonly in a multilayer fashion, using an array of materials including cartilage, fat, acellular dermal graft, and mucosal free grafts. Lumbar drain placement was used in seven cases for an average of 5.6 days. No postoperative CSF leaks occurred. The mean follow-up was 18.0 months (range, 1-56 months). CONCLUSION: This report describes methods for the reconstruction of the skull base after MIER. Reconstitution of the skull base barrier can be achieved through application of principles for surgical repair of CSF rhinorrhea.

Adult↗

Slow-flow phenomena in magnetic resonance imaging of the jugular bulb masquerading as skull base neoplasms.

Enhancement in the region of the jugular foramen on magnetic resonance imaging (MRI) is highly sensitive to the presence of a skull base neoplasm. Unfortunately, this imaging method lacks the specificity to be the sole criterion in the diagnosis of a lesion of the jugular foramen. Although well described in the radiological literature, the phenomenon of gadolinium enhancement of the relatively static blood in the jugular system continues to be erroneously diagnosed as glomus jugulare tumor. Instances of this phenomenon present in patients referred to our practice for surgical opinions before radiation therapy and/or definitive resection will be presented. The purpose of this communication is to bring this potential treatment pitfall to the attention of the neurotology community. Treatment planning for lesions of the lateral skull base cannot singularly be based on MRI findings but requires a healthy skepticism satisfied only by more complete evaluation.

Adult↗

Combined orbito-frontal, sub- and infratemporal fossa approach to skull base neoplasms. Surgical technique and clinical application.

Neoplasms located along the antero-lateral skull base, with probable involvement of the orbit and with extension into the pterygoid and/or infratemporal fossa can usually not be sufficiently exposed using standard neurosurgical or otosurgical approaches, which is why combined approaches to these skull base targets have been developed in the recent past. In this report we describe our experience, using a combined orbito-frontal, sub- and infratemporal fossa approach which, starting with a pre-auricular incision and a standard pterional craniotomy, is extended to an extensive osteoplastic enbloc resection of the orbito-zygomatic area allowing for direct visualisation of the antero-temporo-lateral skull base from the orbital cavity to the depth of the infratemporal and pterygoid fossa. The surgical technique as well as the clinical experiences accumulated with this approach are described.

Chordoma↗

Midfacial degloving for the management of nasal, sinus, and skull-base neoplasms.

The midfacial degloving approach to the midfacial orbital and anterior skull base structures is very versatile. It provides excellent access to a wide range of resections, such as medial maxillectomy, radical maxillectomy with and without orbital exenteration, anterior skull base cranifacial resection, and partial rhinectomy. This technique is useful for removal of benign and malignant lesions. The postoperative complications are rare. Because of absence of external skin incisions the cosmetic results are excellent.

Adult↗

Facial paralysis caused by malignant skull base neoplasms.

OBJECT: Bell palsy remains the most common cause of facial paralysis. Unfortunately, this term is often erroneously applied to all cases of facial paralysis. METHODS: The authors performed a retrospective review of data obtained in 11 patients who were treated at a university-based referral practice between July 1988 and September 2001 and who presented with acute facial nerve paralysis mimicking Bell palsy. All patients were subsequently found to harbor an occult skull base neoplasm. A delay in diagnosis was demonstrated in all cases. Seven patients died of their disease, and four patients are currently free of disease. CONCLUSIONS: Although Bell palsy remains the most common cause of peripheral facial nerve paralysis, patients in whom neoplasms invade the facial nerve may present with acute paralysis mimicking Bell palsy that fails to resolve. Delays in diagnosis and treatment in such cases may result in increased rates of mortality and morbidity.

Adenocarcinoma↗

Facial paralysis caused by malignant skull base neoplasms.

OBJECT: Bell palsy remains the most common cause of facial paralysis. Unfortunately, this term is often erroneously applied to all cases of facial paralysis. METHODS: The authors performed a retrospective review of data obtained in 11 patients who were treated at a university-based referral practice between July 1988 and September 2001 and who presented with acute facial nerve paralysis mimicking Bell palsy. All patients were subsequently found to harbor an occult skull base neoplasm. A delay in diagnosis was demonstrated in all cases. Seven patients died of their disease, and four patients are currently free of disease. CONCLUSIONS: Although Bell palsy remains the most common cause of peripheral facial nerve paralysis, patients in whom neoplasms invade of the facial nerve may present with acute paralysis mimicking Bell palsy that fails to resolve. Delays in diagnosis and treatment in such cases may result in increased rates of mortality and morbidity.

Adenocarcinoma↗

Image-guided surgery for skull base neoplasms using the ISG viewing wand. Anatomic and technical considerations.

Image-guided surgery of the cranial base requires a knowledge of both surgical anatomy and the technical aspects of the particular system being used. The authors report on their experience using the ISG Viewing Wand over the last two years, concentrating on the technical considerations for the use of the system and lessons learned. Image-guided surgical systems may well replace the current forms of intraoperative imaging used for anatomic orientation and localization and are considered a valuable addition to the armamentarium of the skull base surgeon.

Brain Neoplasms↗

Cranioplasty by means of molded polymethylmethacrylate prosthetic reconstruction after radical excision of neoplasms of the skull in two dogs.

Two dogs with osteoma or multilobulated tumor of bone of the skull were treated with large en bloc resections. The resections resulted in exposure of the brain above the horizon line of the remaining calvarium; in 1 dog, the removal of the dorsal orbital rims also exposed both orbits dorsally. Protection of the brain and exposed tissues and restoration of the cosmetic appearance of the skull were attempted by use of molded polymethylmethacrylate prosthetic reconstruction of the calvarium. The technique described involves cranioplasty by use of a preformed molded polymethylmethacrylate implant. Such prosthetic cranioplasty may benefit dogs undergoing radical excision of extensive tumors, and the usefulness and potential complications of its application are discussed.

Animals↗