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At least 19 recordsLinked to original sources
PubMed1984

Advances in diagnosis and management of salivary gland diseases.

Salivary glands may be involved in a wide variety of diseases, which may be broadly grouped into (1) inflammatory, (2) noninflammatory, nonneoplastic and (3) neoplastic categories. Most inflammatory and noninflammatory, nonneoplastic diseases should be managed conservatively and symptomatically. The common exceptions are first-arch branchialcleft cysts and calculi. Neoplastic lesions always require resection if that is feasible. For benign tumors, simple excision with a cuff of normal tissue around it will usually suffice. The prevailing trend for treatment of malignant neoplasms is conservatism. No longer is the facial nerve routinely sacrificed. The resection done is dictated by the tumor size and the facial nerve is spared unless directly invaded. Postoperative radiation therapy is increasingly used.

Cysts↗
PubMed1993

HIV-salivary gland disease. Salivary scintiscanning with technetium pertechnetate.

The salivary disease in two patients with human immunodeficiency virus infection was investigated by technetium pertechnetate scintiscanning. Although there was good histologic evidence of benign lymphoepithelial disease, scintiscanning failed to delineate any salivary lesions. Technetium pertechnetate scintiscanning seems to be of little value in the detailed investigation of salivary disease in human immunodeficiency virus infection, though gallium scanning can help. Fine needle aspiration or biopsy remain the main diagnostic tools.

AIDS-Related Opportunistic Infections↗
PubMed1985

[High-resolution real-time sonography in salivary gland diseases. II: Salivary gland tumors].

74 non-selected patients with suspected tumors of the major salivary glands were examined by high-resolution real-time sonography (7 MHz). The different tumors presented with characteristic but nonspecific echomorphological features. Cysts of the salivary glands, intraglandular lymphadenitis, and paraglandular lesions can be distinguished from real tumors of the salivary glands. In case of uncertain palpatory findings the demonstration of an intact echographic texture pattern proves the absence of a tumor. No false negative ultrasound tumor diagnoses were encountered (sensitivity 100%). In salivary-gland neoplasms high-resolution real-time sonography completes the clinical findings and provides important informations about size, number and type of space occupying lesions.

Adenoma, Pleomorphic↗
PubMedDate not supplied

A revolution in the management of obstructive salivary gland disease.

UNLABELLED: Salivary gland obstruction is the commonest cause of salivary gland disease presenting to the general dental practitioner. To date, with the exception of the most surgically accessible stones found within the anterior ducts, there has been little treatment to offer patients except surgical removal of the gland, with the associated risks to the facial and trigeminal nerves. In the last 10 years, more conservative treatment modalities have been developed, opening up a range of treatment options which combine to provide an alternative management of these cases. This paper presents data from one unit in which lithotripsy, which is the destruction of stones (calculi) using shock waves, basket retrieval, a modified minor surgical technique, and balloon dilatation have been used to treat salivary gland obstruction successfully. Over 70% of stones can now be retrieved leaving a functioning gland. CLINICAL RELEVANCE: Salivary gland obstruction is a clinical problem presenting to the general dental practitioner, and requires an understanding of the range of treatment options available.

Catheterization↗
PubMed1988

Viruses and salivary gland disease: are there associations?

Viruses can cause sialadenitis and may be associated with other diseases of salivary glands, particularly immunologically mediated and neoplastic lesions. The evidence that such an association with Sjögren's syndrome is causal is reviewed here and shown to be fairly tenuous at present.

Animals↗
PubMed1976

[Morphology of salivary gland diseases].

The human salivary glands represent a functional system with manifold responsibilities and interactions to the organism. The major and minor salivary glands show a common construction schedule consisting of an acinar functional system for the production of an enzyme- and mucin-containing primary saliva and a ductal functional system with manifold secretory, resorptive and regulatory responsibilities for the transport and the definitive composition of the saliva. The cyclic AMP and calcium iones localized in the glandular acini have an exceptional importance for the course of the secretory process. The neurohormonal control of the salivary secretion results by adrenergic and cholinergic transmitter substances. Moreover the secretory process shows a daily cycle combined with morphological alterations of the glandular cells (so called circadian structures). The fluid secretion of the salivary duct system (the output of sodium-, potassium- and chlorine-iones) represents an active energy-consumed transport process which will be regulated by several factors (autonomic nervous system, quantity of perfusion, hydrostatic pressure in the blood capillaries, transepithelial active transport by ATP-consumed pump systems). The striated ducts are the functional most important sector of the duct system for a rapid fluid- and electrolyte excretion. The terminal axons of the postganglionic sympathic and parasympathic neurits are characterized by spindle-shaped enlargements (varicosities) which contain neurosecretory granules. In the region of the acinar and intercalated duct cells a direct synaptic contact exists for the stimulation transmission, in the course of which the terminal axon contacts immediately with the effector cell by penetration of the basement membrane. The salivary glands form a part of the stabil tissues with reversible postmitotic cells in regard of the tissue regeneration. Under pathological conditions (inflammations, impediment of secretion fluid, radiation effects etc.) metaplasias and proliferations of the duct system arise with development of indifferent duct formations analogous to the type of an embryonal salivary gland. The terminal zone between intercalated and striated ducts represents an indifferent zone with large regeneratory potency. A special behaviour shows the myoepithelial cells which are developed as well to the outside of primitive embryonic duct buds as differentiated intercalated and striated ducts. Morphologically three types of diseases can be classified in the salivary glands: sialadenosis, sialadenitis and tumours.(ABSTRACT TRUNCATED AT 400 WORDS)

Adult↗
PubMed1987

[Value of sonography and sialography in the diagnosis of salivary gland diseases].

134 patients with diseases of the salivary glands who underwent both real-time sonography and sialography were analyzed retrospectively. Using the two imaging methods a correct diagnosis was established in 92.5% of the patients. Masses of the salivary glands were detected in 98% (60/61) of the cases with the ultrasound examination, in 90% with sialography. The exact differentiation between a peripherally placed intrinsic lesion and an extrinsic mass that is intending the peripheral salivary gland contour often showed to be difficult as well with sialography and sonography. A chronic obstructive or non-obstructive sialadenitis could be correctly diagnosed in 91% of the cases with sialography, but only in 65% using sonography. The results demonstrate the complementary role of sonography and sialography in evaluating salivary gland disease.

Adult↗
PubMed1993

[Evaluation of the panoramic sialography in the diagnosis of salivary gland diseases].

Pantomographic sialography (PS) and traditional sialography (TS) was performed and compared on 106 glands out of 94 patients. The main advantages of pantomographic sialography are: (1) sialectasic lesions of the salivary glands are shown well; (2) small lesions of the main salivary glands are shown well: (3) lesions of the main salivary ducts are shown well; (4) the imaging distortions are minor and the actual situation can be demonstrated well; (5) superimposition of surrounding tissues is avoided, the imagings are more clear; (6) more than one glands can be examined at the same time; and (7) patients are positioned easily and feel more comfortable.

Adolescent↗
PubMed1987

[Value and indications for high-resolution real-time sonography in nontumor salivary gland diseases].

308 patients with salivary gland diseases were investigated using real-time sonography. In 142 patients we suspected neoplasms of the salivary glands on the sonograms. In the remaining 166 patients we investigated the following entities: sialolithiasis (74 patients), acute sialadenitis (54 patients), abscess formation (16 patients), chronic sialadenitis or autoimmune disease (53 patients) and cysts of salivary gland (5 patients). The changes in the sonographic morphology of the different diseases will be described. The role of ultrasound in the diagnosis of the different diseases will be discussed and the indications for sonographic investigations are summarised.

Abscess↗