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At least 19 recordsLinked to original sources

Study of arboviruses in Romania (1958--1978). Results obtained in the "Stefan S. Nicolau" Institute of Virology.

The results obtained in the Institute of Virology by the study of arboviruses in Romania are reviewed. Isolation of tick-borne encephalitis virus and detection of specific serum antibodies in humans, animals and migratory birds demonstrate its presence on the territory of Romania. Serum antibodies could also be detected to other three flaviviruses (West Nile, Ntaya, dengue types 1, 2, 3), though none of them could be isolated in our country. However, isolation of Kemerovo and Tahyna viruses and detection of antibodies to these viruses as well as to Calovo virus draw attention to the possibility of human infections with arboviruses belonging to Kemerovo, California and Bunyavirus groups.

Animals

[History of smallpox vaccination in Romania and source of the IC strains of vaccinia virus].

Smallpox existed in Romania since the 17th century, when both variolation and vaccinia were used for preventing the disease. Jenner's vaccination was performed in 1801 in Cluj and Tirgu Mures and extended to the entire country during the following 31 years. The vaccinia virus strain used for preparing the smallpox vaccine was received in 1893 from the Vaccine Institute of Berlin by Prof. Riegler of the Faculty of Veterinary Medicine, Bucharest. In 1949, it was taken over by the Cantacuzino Institute and has been carried through at most 27 passages in buffalo calves ; it is now designated as strain ICn+m27.

History, 18th Century

[Tuberculosis in Romania (author's transl)].

The incidence of tuberculosis in Romania has decreased considerably over the past years, particularly since 1972 when the combined rifampicin-ethambutol-pyrazinamide therapy was introduced. During the period 1968-1977 it fell from 127.9 per 100,000 to 73.4 per 100,000. The incidence of relapses fell at a slower rate. The most endangered are the 20-24 years age-group and old people; but here again the number of cases tends to fall. Childhood tuberculosis showed a yearly decline by an average of 20%. Bacteriological examinations and diagnosis are assuming increased importance.

Adolescent

Investigations on the presence of antibodies to Tahyna virus in Romania.

Serological results are presented of the HAI reaction to Tahyna virus performed in 1,749 apparently healthy subjects from two countries of Romania where Culex pipiens mosquitoes occur frequently, in 113 febrile patients (some of which exhibited signs of interstitial pneumonia) and in 675 domestic animals (swine, cattle, sheep and goats).

Animals

[Sensitivity to antibiotics and chemotherapeutic agents in some strains of Salmonella typhi isolated in Romania during the period 1974-1976].

Investigations were carried out on 781 S. typhi strains isolated from patients and carriers. Testing of the sensitivity to chemotherapeutical agents by diffusiometry and the incorporation technique led to the detection of four resistant strains: 1 strain isolated by coproculture from a carrier since 1958, resistant to A, K, N, Ca and Cf and 3 strains isolated by coproculture, biliculture and uroculture from a carrier since 1974, resistant to A and Ca. The R factors of these strains were transferred in their totality. The resistant strains did not manifest any particular pathogenicity for the laboratory animal, and their immunogenic potential was below that of the current typhoid vaccine. None of the 781S typhi were resistant to Cmx, C, G, T, Co and Po. Consequently, in Romania Chloramphenicol may be used in continuation in the treatment of typhoid fever, and Cotrimoxazol, Gentamycin, Tetracyclin and Ampicillin are and remain reserve substitutes. The possible unexpected appearance of resistant S. typhi strains demand, however, further control of the sensitivity to chemotherapeutics of all the isolated strains.

Anti-Bacterial Agents