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At least 19 recordsLinked to original sources
PubMed2000

Epidemiology of rheumatic diseases.

Rheumatic diseases are among the oldest diseases recognized. The classification of rheumatic diseases is sometimes difficult due to unknown aetiology and heterogeneity in their clinical presentation. Osteoarthritis (OA) and rheumatoid arthritis (RA) are the two most common rheumatic diseases, accounting for a large percentage of disability worldwide. The economic and social burden of these diseases is great. Their impact on both individuals and society results from a decreased quality of life, lost productivity and increased costs of health care. Without appropriate approaches to patient management and control of these diseases, this impact can be expected to increase as the population ages. One of the challenges in studying OA and RA, and rheumatic diseases in general, is deriving epidemiological data that can be used to understand better the factors that contribute to the initiation and progression of these diseases. Only with such an understanding can significant progress be made in the diagnosis, treatment and management of patients.

Arthritis, Rheumatoid↗
PubMed2002

[Treatment of peptic ulcer related to rheumatic diseases].

Rheumatic diseases often have gastrointestinal(GI) manifestations, and may present as GI bleeding and perforation due to peptic ulcer associated with high mortality. Major causes of peptic ulcer related to rheumatic diseases are drugs such as nonsteroidal anti-inflammatory drug(NSAID) and corticosteroid, and vasculitis. The analgesic effects of NSAID often mask abdominal pain until they cause GI bleeding and perforation. Therefore, it is important to make early diagnosis of peptic ulcer with upper gastrointestinal endoscope. Fundamental treatment of NSAID induced peptic ulcer is to quit it, however it is difficult because of activity of rheumatic diseases. Also, most NSAID induced peptic ulcers heal by administration of proton pump inhibitor or misoprostol. Corticosteroid pulse therapy or administration of immunosuppressant agents is effective for vasculitis induced peptic ulcer, however it is difficult to make diagnosis of it. Development of NSAID with less side effects such as cyclooxygenase-2 selective inhibitors and establishment of diagnosis and treatment of peptic ulcer related to rheumatic diseases are expected.

Anti-Inflammatory Agents, Non-Steroidal↗
PubMed1989

Approach to rheumatic diseases.

Rheumatic diseases are the most prevalent of the chronic painful disorders in the world today. The specialty of rheumatology is one of the most clinically orientated. Hence the approach to rheumatic diseases must be clinical. Proper history taking and physical examination including that of the musculoskeletal system cannot be overemphasized. Special attention must be paid to the skin, mucous membrane, the eyes, the gastrointestinal and genitourinary systems. Laboratory tests are meant to supplement a thorough history and physical examination and never in place of them. Because there is so much overlap in the clinical manifestations of the different rheumatic diseases, a precise diagnosis may be difficult in the early stages. Management goals must therefore be bipartite. Short term goal is aimed at symptomatic relief, gaining the patient's confidence and preventing disability. Long term goal requires the physician's attention to diagnosis and prognosis, drug toxicity, negotiating with the patient regarding an acceptable life-style and degree of relief and finally prolonging or protecting life. In fact the modern approach to health care delivery in rheumatic diseases must be based on the team concept. The team should consist of the physician/rheumatologist, the orthopaedic surgeon and a spectrum of arthritis health professionals composed of physical therapists, occupational therapists, nurses, psychologists, social workers, dietitians, bioengineers and administrators.

Health Services Needs and Demand↗
PubMed1976

[Psychsomatic aspects of rheumatic, especially soft tissue rheumatic diseases].

Rheumatic diseases may be connected to varying degrees with psychic factors. On the one hand, rheumatic diseases may produce psychic reactions, while on the other hand rheumatic symptoms--especially in extra-articular rheumatism--may be induced by psychosomatic hysteric pararheumatic diseases and depressive mechanisms. Special reference is made to psychosomatically induced extra-articular rheumatic diseases in which not only the complex genesis but also the clinical symptomatology are discussed. During therapy more attention should be directed to psychic factors than in the past, as only an intensive psycho and/or psychopharmacotherapy can influence the disease.

Adult↗
PubMed2002

[Radiologic diagnosis of rheumatic diseases].

Rheumatic disease have many common radiological characteristics. They all affect one or more joints. Radiological exams represent a part of the diagnostic procedure when there is a suspicion of rheumatic disease. This paper describes both the basics and characteristics radiological changes visible on a classic radiograph which, in addition to other results, allow the discrimination of different rheumatic diseases. Standard or classical radiographs are the cornerstones of radiological evaluation, and can be improved by other radiological methods such as US, CT or MR.

Humans↗
PubMedDate not supplied

Orofacial manifestations in the rheumatic diseases.

Rheumatic diseases will often affect the temporomandibular joint, but other orofacial tissues may also show manifestations. This article, based on a lecture given at the Royal National Hospital for Rheumatic Diseases, Bath, is intended to help the dental practitioner recognize and treat these symptoms.

Adult↗
PubMed2001

Development, content, and process evaluation of a coping intervention for patients with rheumatic diseases.

Rheumatic diseases, like many other chronic diseases, represent an important public health problem. To reduce the impact of rheumatic and other chronic diseases, the appropriate management of these conditions should be encouraged through the use of established educational programs. This article describes the development and content of a coping intervention for groups of patients with rheumatic diseases aimed at increasing social support and quality of life. Patients' and supervisors' perceptions of the coping intervention as the results of a process evaluation will also be discussed. The purpose of this paper is to provide information for health educators who want to use the coping intervention with patients with rheumatic diseases or who want to develop a similar intervention for other target populations. Results of the process evaluation show that the intervention was well received by the patients as well as the supervisors.

Adaptation, Psychological↗
PubMed2006

The pharmacoeconomics of newer therapeutics for rheumatic diseases.

Rheumatic diseases are common, serious conditions characterized by alterations in normal immune homeostasis with resultant end-organ injury. Although diverse in clinical expression and pathophysiologic basis, therapeutic approaches for these conditions frequently overlap. Over the past decade, several important new therapies have been introduced into the clinic for the treatment of many rheumatic conditions. Although these agents have proven highly effective, their higher costs have raised questions concerning their most appropriate use in the clinic. This issue has been analyzed in greatest detail in rheumatoid arthritis. Increasing data suggest that newer therapeutics may be cost-effective for rheumatoid arthritis and other rheumatic diseases.

Antirheumatic Agents↗
PubMed2003

Endothelial nitric oxide synthase gene polymorphisms in Behçet's disease and rheumatic diseases with vasculitis.

OBJECTIVE: To assess potential associations between Korean Behçet's disease (BD) or other rheumatic diseases with vasculitis and two polymorphisms of the endothelial nitric oxide synthase (eNOS) gene, which include the Glu298Asp polymorphism in exon 7 and a variable number of tandem repeats (VNTR) polymorphism in intron 4. METHODS: 65 patients with BD, 27 with rheumatic diseases with vasculitis, and 80 controls were studied. Analyses of the Glu298Asp polymorphism in exon 7 and VNTR polymorphism in intron 4 of the eNOS gene were made by the polymerase chain reaction (PCR)-restriction fragment length polymorphism technique and PCR genotyping, respectively. Additionally, HLA-B51 typing was performed in the BD group and controls by a two step PCR sequence-specific primers method. RESULTS: Significant differences in Glu298Asp genotype frequencies were found between the BD or vasculitis groups and the controls (BD group v controls: p(corr)=0.006; vasculitis group v controls: p<0.001). The Asp298 frequency was much higher in the BD and vasculitis groups than in the controls. Even after stratification of the BD group based on the results of HLA-B51 testing, a significant association of the Glu298Asp polymorphism was still found (p=0.002, Mantel-Haenszel weighted odds ratio 4.3, 95% confidence interval 1.7 to 10.9). Distribution of the genotype frequencies in two eNOS gene polymorphisms was similar in connective tissue diseases-associated vasculitis and primary vasculitic syndromes. In contrast, distribution of alleles and genotypes of VNTR polymorphism did not differ between BD or vasculitis groups and the controls. CONCLUSION: The Glu298Asp polymorphism in exon 7 of the eNOS gene seems to be a susceptibility gene for Korean BD and other rheumatic diseases.

Adult↗
PubMed1990

Introduction to rheumatic disease.

Rheumatic diseases are very common. They comprise one of the commonest causes of consultation by patients with general practitioners and hospital specialists. There are considerable financial implications for the community, as well as morbidity for the patient. Inflammatory and non-inflammatory categories are the major subdivisions of this group of over 200 diseases. They involve the joints, the bones, the muscles and connective tissue throughout the body.

Female↗
PubMed2000

[News in the treatment of rheumatic diseases].

Rheumatic diseases are frustrating issue for the rheumatologists because ethiologic remedy is still missing and much more, they are great socio-economic burden for patients and society. In the last 10 years there was bustling endeavour in creating new products with exact known action. This article deal the new options to treat rheumatoid arthritis with leflunomide, infliximab, etanercept and anakinra and osteoarthritis with hyaluronan, diacerhein, glucosamino sulphate, chondroitin sulphate and avocado/soya unsaponifiables. In particular patients all mentioned products have their place in the treatment plan but critical risk-benefit assessment is needed.

Humans↗
PubMedDate not supplied

Soft tissue problems associated with rheumatic disease.

Rheumatic disease and associated soft tissue problems encompass a large number of syndromes and account for a high percentage of visits to primary care practitioners. This article describes the symptoms, causes, and treatments for five of the problems most commonly encountered: bursitis, tendinitis, carpal tunnel syndrome, myofascial pain syndrome, and fibromyalgia. Effective management requires a structured history, physical examination, and definitive diagnosis that distinguishes the soft tissue problem from a joint problem and an inflammatory syndrome from a noninflammatory syndrome. The overriding principle is self-management of treatments that focuses on relief of pain, maintenance of function, and avoidance of factors that cause recurrence or exacerbation of the problem. Medications, physical therapies, biomechanical aids, and exercise strategies, along with cognitive-behavioral techniques for the more chronic problems, are all known to decrease symptoms and to assist patients in returning to normal functioning.

Bursitis↗