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Peritonsillar abscess, retropharyngeal abscess, mediastinitis, and nonclostridial anaerobic myonecrosis: a case report.

Peritonsillar abscess is a potentially life-threatening complication of acute tonsillitis. On occasion, peritonsillar abscess can extend to neck spaces and/or to the mediastinum. We describe a case of a patient with a peritonsillar abscess that extended to the neck, producing bilateral retropharyngeal abscesses and myonecrosis of the strap muscles. Culture of a specimen of the necrotic muscle yielded Prevotella intermedia, Prevotella buccae, Lactobacillus catenaforme, another Lactobacillus species, Peptostreptococcus anaerobius, and some nonanaerobes. Culture of the peritonsillar abscess yielded P. intermedia and P. buccae plus P. anaerobius, Peptostreptococcus asaccharolyticus, Bifidobacterium dentium, viridans and group F streptococci, and Citrobacter diversus. Culture of the retropharyngeal abscess yielded Fusobacterium nucleatum and Actinomyces odontolyticus in addition to most of the aforementioned organisms. The patient underwent repeated drainage and debridement procedures and was treated with various antimicrobial agents and ultimately recovered. This case highlights the polymicrobial nature of peritonsillar abscess and the serious complications that this infection may lead to.

Abscess↗

Clinical indicators of childhood retropharyngeal abscess.

Retropharyngeal abscess is a rare but distinctive cause of airway obstruction in childhood. Early recognition permits emergent airway management and surgical drainage. Even when the presentation is insidious and does not include respiratory compromise, early clinical diagnosis of retropharyngeal cellulitis and appropriate medical treatment may halt progression to an abscess. Delay in the diagnosis and management of a retropharyngeal abscess may lead to potentially lethal complications involving vital structures. A case of an infant whose diagnosis of retropharyngeal abscess was delayed because of absence of respiratory compromise is reported. Relapse of retropharyngeal abscess despite surgical drainage and appropriate antibiotic treatment was a complication of infection in this patient. Clinical indicators providing an early diagnosis of retropharyngeal infection, and aspects of evaluation, management, and outcome, are discussed.

Anti-Bacterial Agents↗

Cervical vertebral osteomyelitis presenting as a retropharyngeal abscess.

Retropharyngeal abscess as a manifestation of nontuberculous cervical vertebral osteomyelitis in adults has been described rarely in the literature. We report a case of cervical vertebral osteomyelitis that was caused by Staphylococcus aureus and that presented as a retropharyngeal abscess in a 66-year-old man. In addition, we review related cases.

Aged↗

Paediatric retropharyngeal abscess.

Retropharyngeal abscess (RPA) is an uncommon condition with the potential for significant morbidity and mortality if not detected early. The authors present a case report of a 19-month-old child who presented with the common clinical features of a retropharyngeal abscess and in whom the diagnosis was not established by examination and ultrasonography. This led to a delay in appropriate management until a computed tomography (CT) scan was performed under general anaesthesia. The scan demonstrated the diagnosis and surgical drainage was performed under the same anaesthetic. The child subsequently made a complete recovery. The investigation and treatment of RPAs is a matter of some debate and the authors review the recent literature to determine the best management strategy.

Drainage↗

Transverse cervical myelopathy: an unusual complication of retropharyngeal abscess.

Retropharyngeal abscess complicated by suppuration in the central nervous system, intra- or extraaxial, is rare. Acute transverse myelopathy complicating a retropharyngeal abscess may be more frequent than epidural spinal abscess and usually affects the thoracic cord. Therefore, the occurrence of acute high cervical transverse myelopathy is rarely encountered and warrants reporting. The need for neuroradiologic diagnostic evaluation is emphasized in order to rule out a surgically treatable lesion.

Abscess↗

[Mediastinal extension of retropharyngeal abscess].

Retropharyngeal abscesses in children are unusual and the involvement of the mediastinum is exceptional since the era of the antibiotics. It can be explained by the anatomic continuity between the retropharyngeal space and the retrooesophageal space. We report a case where the CT Scanner allows a complete evaluation of the disease in the mediastinum and a good follow-up.

Abscess↗

[A case of spinal epidural abscess associated with retropharyngeal abscess].

Spinal epidural abscesses are known to occur associated with retropharyngeal abscess, but such cases are few in the literature. We treated a 72-year-old woman who reported pain in the back of the neck. Computed tomography (CT) showed a retropharyngeal abscess extending to the upper neck through the carotid space on the left side and an magnetic resonance imaging (MRI) showed a spinal epidural abscess without cervical vertebral osteomyelitis. The abscess was assumed to reach the epidural space along the nerve root through the intervertebral foramen. Since tonsillitis appeared to cause the retropharyngeal abscess, we performed tonsillectomy, and then drained pus through the superior constrictor muscle, effecting a subsequent cure. Staphylococcus aureus was recovered from both the pus and tonsil, and Streptococcus constellatus, a member of the Streptococcus milleri group, from the tonsil. Based on a review of the literature, clinical courses of spinal epidural abscess associated with retropharyngeal abscess are not always simple, as 4 of the 7 cases found demonstrated poor prognosis. Spinal epidural abscess should be considered a critical complication of retropharyngeal abscess.

Aged↗

Retropharyngeal abscesses in children revisited.

Retropharyngeal abscess appears in infancy and early childhood. Because of the advances in antibiotic therapy, the frequency of this disease has decreased considerably. If overlooked, however, the sequelae of retropharyngeal abscess can be disastrous. Of the typical signs and symptoms listed in presentation, the swelling of the posterior pharyngeal wall is referred to as an important diagnostic sign. This presentation will discuss the fallibility of this important sign in the evaluation of a retropharyngeal abscess in children. The size of the pediatric oral cavity and the presence of pooling secretions in the pharynx, due to retropharyngeal tissue swelling, make assessment of swelling of the posterior pharyngeal wall extremely difficult. Radiological assessment of retropharyngeal abscesses cannot differentiate between cellulitis and abscess formation. The presentation will discuss the radiological appearance of a retropharyngeal swelling and discuss the differentiation of abscess formation from cellulitis. The rationale for a therapeutic regime will be developed to validate the concept that with suggestive clinical signs, suggestive radiological diagnosis, and in spite of negative evidence of retropharyngeal swelling by oral examination, justification exists for an examination under anesthesia and incision and/or aspiration of the retropharyngeal abscess.

Abscess↗

[Retropharyngeal abscess in adults].

BACKGROUND: Retropharyngeal abscess is a rare disorder usually seen in children as a result of upper respiratory tract infections. In adults, retropharyngeal abscess can occur as a result of local trauma (such as foreign body ingestion or instrumental procedures) and odontogenic infections. PATIENTS AND METHODS: We report two cases of retropharyngeal abscess in adults. The clinical features, diagnostic procedures and treatment of the disease are discussed. RESULTS: Foreign body ingestion (fish bone) was the predisposing factor in one patient and no underlying cause was found in the other. Diagnosis was established by computed tomography of the neck. S. mitis and S. oralis were isolated in the culture of the abscess secondary to foreign body ingestion. Antibiotic treatment was successful in both cases without evidence of complications. Surgical drainage was not required. CONCLUSIONS: Antibiotic therapy is a useful alternative treatment to surgery in the management of non-complicated retropharyngeal abscess.

Adult↗

Retropharyngeal abscess in children.

BACKGROUND: Retropharyngeal abscess (RPA) is an uncommon, potentially fatal condition found more frequently in children than adults. Prompt diagnosis and surgical management of this condition is imperative to prevent complications including airway obstruction and mediastinitis. Few studies have been dedicated to paediatric retropharyngeal abscess. METHODS: A retrospective analysis of 21 cases of retropharyngeal abscess at the Sydney Children's Hospital over a 12-year period was performed. RESULTS: There were 12 boys and nine girls involved in the analysis. Their ages ranged from 3 months to 12 years. Common -presenting symptoms and signs included fever, dysphagia, neck swelling and torticollis. Respiratory compromise was present in 29% of the children at presentation. Foreign body ingestion accounted for 10% of cases. Seventeen cases were managed with surgical drainage. Surgical approaches adopted included transoral (70%), external cervical approach (20%) and a combined approach in 10%. There was no mortality. Mediastinitis occurred in two patients, one of whom also had recurrent laryngeal nerve palsy. No other serious complications occurred. CONCLUSION: Retropharyngeal abscess should be considered in all children presenting with neck pain and dysphagia. Prompt diagnosis and institution of appropriate medical and surgical therapy is imperative to prevent complications such as airway obstruction. The management of this condition should occur in a paediatric institution with appropriate medical, surgical and intensive care -facilities.

Child↗

Retropharyngeal abscess: a clinical review.

Retropharyngeal abscesses are uncommon but potentially lethal infections, especially in the paediatric population under the age of five years. Abscesses in this group are classically secondary to upper respiratory infections especially oropharyngeal infections, while in the adult group they are usually secondary to trauma, foreign bodies, or as a complication of dental infections. Early diagnosis and the wide spread use of antibiotics have made these infections less common today. Between the years 1985-1996, 19 cases of retropharyngeal abscesses were treated in our department. Factors such as age, sex, aetiology, presenting signs, symptoms, methods of diagnosis, treatment and complications were reviewed. Thirty-two per cent of the cases were secondary trauma. A lateral neck film showing widening of the prevertebral space was the most important diagnostic tool, computed tomography (CT) scan was used in 63 per cent of cases to verify the signs of an abscess and to provide more accurate anatomical localization. Thirteen cases required surgical drainage. The single most commonly-isolated pathogen was Streptococcus pyogenes. There were no deaths and only one recurrence requiring repeated surgical drainage. One case was complicated by a spinal canal abscess. We also report two cases of retropharyngeal abscess in children caused by swallowing of unusual foreign bodies.

Adolescent↗

Retropharyngeal abscess: clinical review.

Retropharyngeal abscess, once a relatively common entity in children, is uncommon today. From 1981 to 1991, we treated 20 cases. Abscesses secondary to upper respiratory infection in children were seen only in three (15%) cases. Trauma and foreign bodies were the most common etiologic factors in the adult subgroup. Streptococcus viridans and Klebsiella pneumoniae were the most common pathogens. The use of contrast-enhanced computed tomography has had a significant impact on the diagnostic work-up. The choice of initial antibiotic therapy is discussed. There were no deaths in this series.

Adolescent↗

Retropharyngeal abscess: recent trends.

Retropharyngeal abscess (RPA) is relatively rare today. A study of 17 cases of RPA treated at our hospital in the past 10 years showed a shift in the disease from children below 6 years of age (41%) to older children and adults (58%). Upper respiratory tract infection (URTI) was found to be the commonest (52%) aetiological predisposing factor in all age groups. Other aetiological factors were septicaemia (11%) in children below the age of 6 years and trauma due to foreign body (35%) in the older children and adult age groups. Klebsiella, Staphylococcus and Streptococcus were the commonest species of microorganisms grown from pus. The changing clinical trends, microbiology, choice of antibiotics, usefulness of radiology, and complications of this potentially fatal illness are discussed.

Adolescent↗

Retropharyngeal abscess--the foreign body connection.

Retropharyngeal abscesses have been described to be more common among children especially under the age of three or four years and oropharyngeal infection have been implicated as a common etiological factor. However, this series reveals that retropharyngeal abscesses are more commonly seen in adults in our local population. Regional trauma resulting from an ingested foreign body is the leading cause of retropharyngeal abscess in this series. Twenty-three patients seen consecutively between January 1983 and June 1989 at the Department of Otolaryngology, Singapore General Hospital were reviewed retrospectively. Factors such as age, sex, racial distribution, presenting symptoms and signs, methods used to arrive at diagnosis, therapy and complications were studied and analysed. A lateral radiograph of the neck was the single most valuable investigation in the evaluation of the retropharyngeal space. Retropharyngeal and retrotracheal width were measured in 210 normal lateral neck radiographs to establish a normal range in our population. Retropharyngeal widening greater than 5 mm and retrotracheal widening greater than 15 mm was considered significant and was noted in all 23 patients. Regional trauma resulting from an ingested foreign body was the cause of the retropharyngeal abscess in thirteen (56.5%) patients.

Abscess↗

[Retropharyngeal abscess: report of 2 cases].

Retropharyngeal abscesses are uncommon and their frequency has decreased since the development of antibiotics. It is important to recognize this serious condition in order to begin treatment promptly. The causes of these processes differ in children and adults, as do the symptoms of presentation. Lateral cervical radiography and CT are diagnostic in only a few cases. Treatment is abscess drainage. Two cases of retropharyngeal abscess are reported. The first case occurred in a child and was due to infection of Waldeyer's lymphatic ring. The second occurred in an adult as a result of foreign body trauma.

Adult↗

Recognition of retropharyngeal abscess in children.

Retropharyngeal abscess is a rare deep-neck infection that usually affects young children. Swelling in the neck can lead to sudden and fatal airway obstruction. Enlargement of lymph nodes located between the posterior pharyngeal wall and the prevertebral fascia occurs secondary to infection of the nasopharynx, paranasal sinuses or middle ear. Penetrating trauma or foreign-body penetration may also lead to abscess formation. Common symptoms include fever, swollen neck, difficult swallowing, muffled voice and hyperextension of the head and neck. Lateral neck radiographs confirm the diagnosis. Early surgical treatment prevents serious complications, such as mediastinal spread, aspiration of pus, airway obstruction or erosion into a major vessel.

Abscess↗

[Peritonsillar and retropharyngeal abscesses: study of 13 years].

INTRODUCTION: Peritonsillar and retropharyngeal abscesses are the most common deep head and neck infections. We present a series of patients with these infections. MATERIAL AND METHODS: We performed a retrospective study of peritonsillar and retropharyngeal abscesses in children admitted to the Infectious Diseases Unit of our hospital between January 1991 and January 2004. Diagnosis was based mainly on clinical and laboratory findings. RESULTS: We studied 54 patients, 10 with retropharyngeal abscess and 44 with peritonsillar abscess. The mean age was 6.7 and 7.5 years respectively. There was a slight predominance of boys (1.45:1). The number of cases diagnosed increased from 1997, with a maximum (nine cases) in 2002. Twenty-nine children had received previous antibiotic therapy. The main symptoms and signs were: fever, odynophagia, cervical lymphadenitis, and asymmetric tonsillar hypertrophy. All children received intravenous antibiotic therapy. Puncture-aspiration was carried out in seven patients. Eleven children underwent tonsillectomy, two with retropharyngeal abscess and nine with peritonsillar abscess. Of these 11 patients, five had had several episodes of tonsillitis and three had previously had a peritonsillar abscess. Three children who developed an abscess had previously undergone tonsillectomy. In most patients, outcome was favorable. CONCLUSIONS: In the last few years the frequency of peritonsillar and retropharyngeal abscesses has increased in the pediatric population. Most of the children have a good response to conservative treatment. The main risk factor for abscess recurrence is a previous history of repeated tonsillitis. Consequently, these patients are candidates for tonsillectomy.

Adolescent↗

Colour Doppler ultrasonography of retropharyngeal abscess.

OBJECTIVE: This study was conducted to determine the capability of colour Doppler ultrasonography (CDU) in evaluating retropharyngeal abscess in children. MATERIALS AND METHODS: From July 1996 to February 1998, five children with clinical suspicion of retropharyngeal abscess were evaluated by CDU. The distance from internal carotid artery (ICA) to cervical vertebra (CV) (DICA-CV) at the upper cervical level was measured by longitudinal ultrasonography. Fifty healthy children, aged from 1 to 15 years, were recruited in the study to measure DICA-CV as control. Colour Doppler ultrasonography was used to differentiate abscess from other pathology and to detect carotid sheath invasion. Computed tomography was performed to confirm the sonographic diagnosis. Measurements of the DICA-CV at regular intervals were performed to monitor the progression of retropharyngeal abscess. RESULTS: Retropharyngeal abscess was highly suspected in all cases under sonographic studies. A patient was found to have carotid sheath invasion. Computed tomography confirmed the diagnosis of retropharyngeal abscess in all cases. Retropharyngeal abscess can be evaluated by the measured DICA-CV. The DICA-CV decreased as the retropharyngeal abscess gradually resolved. CONCLUSION: Colour Doppler ultrasonography offers a sensitive method to evaluate retropharyngeal abscess in children. It can also be used to monitor the progression of retropharyngeal abscess and avoid unnecessary radiologic examinations.

Adolescent↗