Search PubMedSearch

SEARCH · Search PubMed

Results for “Radiodermatitis”

Search indexed PubMed citations on genomics, clinical trials, systematic reviews and public health. Explore titles, authors and supplied subject terms, then open the PubMed record.

Quote a phrase for an exact phrase match. Source license links do not imply unrestricted reuse.

At least 19 recordsLinked to original sources

[Radiodermatitis].

All radiations that cross the skin to reach the target organ may produce dermatitis. The skin reaction essentially depends on the total dose delivered, but the fractioning of that dose and its distribution over time are important factors. As benign lesions are no longer irradiated and as accidental or occupational exposure to radiations has become exceptional, the main cause of these lesions is irradiation of malignant tumours, increasingly combined with supportive treatments. Owing to technical improvements radiodermatitis is now less frequent than formerly. Acute radiodermatitis clinically resembles burns. Chronic radiodermatitis may follow the acute phase or occur suddenly after a latent period, sometimes very long. An untractable ulceration developed on an area previously irradiated should suggest malignant degeneration which is by no means infrequent. The best treatment of radiodermatitis is prevention, but plastic surgery has progressed, and patent lesions can now be removed in one stage (skin and muscle), thus transforming the patients' life, previously made very uncomfortable by invalidating lesions.

Humans

Radiation-induced skin cancer and radiodermatitis of the head and neck.

From a cohort of 2400 patients who had been irradiated 19 to 48 years previously for benign diseases in the head and neck region a randomly selected group of 605 patients was selected and traced back. From the 360 patients alive, 257 were examined clinically and 49 were examined by questionnaire for radiation-induced skin tumors and radiodermatitis. In 21 patients, a total of 30 skin tumors were diagnosed. In 8 of 21 patients, 10 skin carcinomas were detected at recall. A dose-effect relationship of 40 carcinomas/10(4) persons/Gy for a median follow-up period of 41 years for the area exposed was calculated. The severity of radiodermatitis is associated with a higher prevalence of skin cancer. The number of radiation-induced skin cancers rises with the post-treatment time. Because of these late radiation effects, radiotherapy of benign skin lesions is contraindicated, especially now that other therapy modalities are available.

Age Factors

Acute radiodermatitis from occupational exposure to iridium 192.

Industrial radiography using the man-made radioisotope iridium 129 is commonplace in the southern states. Despite established procedures and safeguards, accidental exposure may result in typical acute radiodermatitis. We have presented a clinical example of this phenomenon.

Acute Disease

Occupational radiodermatitis from Ir192 exposure.

3 cases of occupational radiodermatitis from Ir192 exposure in personnel handling a gamma ray projector in industrial radiography are presented. The diagnosis was confirmed histologically. The nature and use of the industrial machines are described.

Adult

[Capillaroscopic and clinical correlations in chronic occupational radiodermatitis].

72 patients (69 M, 3 F) occupationally exposed to X-rays were subjected to a clinical and capillaroscopic evaluation so as to determine the morphological changes occurring within the skin and the microcirculatory system. The two parameters were correlated showing that microvasal lesions appear before clinical signs become evident. Therefore, the authors underline the importance of adding periodic capillaroscopic exams to the clinical control in order to prevent the occurrence of occupational chronic radiodermatitis.

Adult