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[Radionuclide radiation monitoring].

Radionuclide radiation monitors used nowadays can operate fairly well in measuring the parameters of the radiation type for which they are intended and calibrated. However, in many cases (particularly in emergency situations) the detector is exposed at a time to several types of radiation. Under such conditions its readings may be noticeably influenced by concomitant radiation. In view of this fact interpretation of the measurement data is embarrassing. Bearing this in mind, it is advisable that the available monitors be modernized and new ones be devised for mixed radiation with the common equivalent surface thickness amounting to 1 g/cm2 of tissue equivalent substance.

False Negative Reactions

Liquid crystal electromagnetic radiation monitor.

Liquid Crystals having color play centered at different temperatures are arranged on metal coated and nonmetal coated dielectric substrates and used to monitor electromagnetic radiation. While both substrates respond to changes in ambient temperature conditions, the metallized substrate will also have temperature changes due to absorbed radiation. The temperature-dependent light scattering properties of the liquid crystals are used as both the temperature measuring mechanism and the indicating mechanism, with the difference between the temperature indications of the two substrates being a measure of the radiation. An experimental model that measures radiation of 1 to 15 mW/cm2 at 2.45 GHz is described.

Calorimetry

Update on the independent radiation monitor (IRM).

The new independent radiation monitor (IRM), unlike its predecessor, is a reliable and sensitive safetly device for any radiation therapy room. It shows unequivovally that the beam is on, and it is inexpensive and simple to construct.

Radiation Monitoring

[Radiation monitoring in the area of metallic dental replacement during cobalt 60 gamma radiation and in electron radiation of oral tumors].

In the radiotherapy of malignant tumors of the oral cavity, the exact distribution of radiation dosage in the neighborhood of metallic dental replacement has been uncertain so far. Many authors therefore asked that crowns and bridges be removed before radiotherapy. By means of lithium fluoride thermo-luminescence dosimetry, punctate measurements of doses are possible for the first time. In view of the dose values obtained, removal of metallic dental replacement before the beginning of radiotherapy as a prophylactic measure to prevent radioosteomyelitis appears not to be necessary.

Cobalt Radioisotopes

The use of sequential fine-needle aspiration biopsy with flow cytometry to monitor radiation induced changes in breast carcinoma.

Thirteen patients with locally advanced or recurrent breast carcinoma were monitored during radiation therapy by multiple, sequential, fine-needle aspiration biopsies (FNAB) with flow cytometry. The material was analyzed for qualitative cytomorphological evidence of radiation effect and for DNA content and cell cycle alterations. DNA ploidy was not affected by the radiation therapy, although the aneuploid tumors showed an increased frequency of cell cycle alterations. The most common change seen was an increase in S-G2M (58%). Other changes included a decrease in the proliferative/growth fraction (17%) and no significant redistribution of cells (25%). There was a relationship between the initial proliferative activity of the tumors and the type of cell cycle change which occurred. Flow cytometric analysis was a better predictor of early clinical response than was cytomorphological assessment. Sequential FNAB with flow cytometry is an effective method of monitoring the response of breast cancer to radiation therapy.

Biopsy, Needle