[Creative experience and psychotic experience].
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Adolescent↗
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[For a logic of the psychotic experience].
The psychotic experience is often seen as qualitatively different from normality. Empirical data show that psychotic symptoms have to be described on a continuum between normality and psychosis. A model of construction of delusional ideas starting from making sense of perceptual aberrations integrating reasoning styles, personal and cultural variables is presented. This model also show how delusional ideas are maintained through bias of selection and behaviors associated with delusional ideas which are naturally reinforced in natural environments. Cognitive-Behavior Therapy (CBT) for psychotic symptoms is a validated psychological set of techniques useful to treat persistent psychotic symptoms. CBT is presented as a five steps intervention including: engagement and assessment, education and normalization of psychotic symptoms, verbal questioning of evidences supporting the beliefs, reality testing and consolidation.
Behavior Therapy↗
Childhood victimisation and developmental expression of non-clinical delusional ideation and hallucinatory experiences: victimisation and non-clinical psychotic experiences.
BACKGROUND: Victimisation in childhood may be associated with adult psychosis. The current study examined this association in the crucial developmental period of early adolescence and investigated whether (1) unwanted sexual experiences, and (2) being bullied, were associated with non-clinical delusional ideation and hallucinatory experiences in a general population sample of 14 year olds. METHODS: Data were derived from standard health screenings of the Youth Health Care Divisions of the Municipal Health Services in Maastricht, the Netherlands. A self-report questionnaire was filled out by a total of 1290 adolescents to assess non-clinical psychotic experiences, as well as experiences of being bullied and sexual trauma. RESULTS: Non-clinical psychotic experiences were strongly and independently associated with both bullying (OR=2.9, 95% CI 1.8-4.8) and sexual trauma (OR=4.8, 95% CI 2.3-10.1). CONCLUSIONS: The results suggest that reported associations between childhood victimisation and adult psychosis can be understood in a developmental framework of onset of at-risk mental states in early adolescence. In addition, the data suggest that the traumatic experience of being bullied may also feed the cognitive and biological mechanisms underlying formation of psychotic ideation.
Adolescent↗
Do different psychotic experiences differentially predict need for care in the general population?
INTRODUCTION: The pathway from subclinical psychotic experiences to need for care may depend on type of psychotic experience, level of associated distress, and previous experience of psychosis. METHOD: In a general population sample with no previous Diagnostic and Statistical Manual of Mental Disorders , Revised Third Edition , psychotic disorder (n = 4722), 83 subjects displayed at least one psychotic experience. Within the group of 83, subjects with (n = 24) and without need for care (n = 59) were compared. Presence of psychotic experiences at younger ages had been assessed at earlier interviews. RESULTS: Of 7 different psychotic experiences, only hearing voices, nonverbal hallucinations, and passivity phenomena were significantly associated with need for care. These associations were largely explained by the distress associated with the psychotic experience, but whether individuals had had psychotic experiences at earlier ages did not matter. CONCLUSIONS: Different psychotic experiences differ in the associated level of need for care and the mediating role of distress. Longer prior exposure to psychosis may not influence the pathway from subclinical to clinical.
Adolescent↗
Early trauma may increase the risk for psychotic experiences by impacting on emotional response and perception of control.
OBJECTIVE: Exposure to early trauma may increase the risk of dysfunctional responses to anomalous psychotic experiences resulting in psychotic symptom formation. METHOD: In a three-wave longitudinal general population study, 4045 never-psychotic individuals exposed and non-exposed to trauma before the age of 16 years, according to baseline interview were interviewed for the onset of psychotic experiences 3 years later (T2). In 36 individuals with incident psychosis at T2, assessments were made, for each psychotic experience, of i) the amount of distress associated with and ii) the degree of coping and subjective control over the experience. RESULTS: In the 16 observations of an incident psychotic experience, in the absence of distress, the baseline rate of early trauma was low (6%), whereas it was much higher in the 21 observations of an incident psychotic experience with distress [43%; odds ratio=10.0, 95% confidence interval (CI): 1.04, 96.3; P=0.046]. Similarly, coping attempts in the context of early trauma was associated with less control (reduction of 2 points on a seven-point scale, 95% CI: -4.0, -0.07). CONCLUSION: Early experience of trauma may create lasting cognitive and affective vulnerabilities to develop clinical symptoms arising out of early, non-clinical psychotic experiences.
Adaptation, Psychological↗
The incidence and outcome of subclinical psychotic experiences in the general population.
OBJECTIVES: To examine the incidence and 2-year stability and outcome of subclinical psychotic experiences in the general population. DESIGN: The Netherlands Mental Health Survey and Incidence Study (NEMESIS), a longitudinal general population study. METHODS: A representative population sample of 7,076 participants was interviewed with the composite international diagnostic interview at baseline, 1 year later at T(1) and again 2 years later at T(2). A sample of individuals was identified who had onset of a new, broadly defined psychotic experience between baseline and T(1) (N = 79; incidence = 2%). Stability and outcome of these incident positive psychotic experiences was reassessed by interview at T(2), at which 25 individuals had a CIDI rating of broadly defined psychotic experience (subclinical outcome) and 11 individuals had psychotic experiences with functional impairment and need for care (clinical outcome). RESULTS: The majority of individuals with an incident psychotic experience did not display persistence of the experience. Only 8% of individuals with a T1 incident psychotic experience had evidence of a T2 subclinical outcome, and only 8% had evidence of a T2 clinical outcome. The emotional context and the number of the T1 incident psychotic experiences were strong modifiers of predictive power for the clinical outcome, but not (or to a much lesser extent) for the subclinical outcome. CONCLUSIONS: The incidence of positive psychotic experiences in the general population is around 100 times greater than traditional estimates of incidence of psychotic disorder such as schizophrenia. The far most likely outcome for these experiences is discontinuity. For the small proportion who display continuity, there is an equally large likelihood of subclinical and clinical 2-year outcomes. Emotional appraisal and degree of intrusiveness of psychotic experiences are important modifiers not for continuity per se but for clinical outcome specifically.
Adolescent↗
Self-reported psychotic experiences in the general population: a valid screening tool for DSM-III-R psychotic disorders?
OBJECTIVE: To examine the diagnostic value of self-reported psychotic-like experiences for DSM-III-R psychotic disorders. METHOD: A general population sample of 7076 subjects aged 18-64 years was interviewed with the Composite International Diagnostic Interview (CIDI) and, if there was evidence of psychotic experiences, the Structured Clinical Interview for DSM-III-R. RESULTS: The probability of having a psychotic disorder increased in a dose-response fashion with the level of self-reported psychotic experiences, but individual CIDI psychotic experience ratings had relatively low post-test probabilities (PPs) (range: 5.1-26.5%). However, limiting the sample to individuals who had been in contact with mental health services substantially improved PPs (range: 13.3-43.1%). CONCLUSION: Screening for psychosis in the population carries a high risk of stigmatization in false-positive cases and violation of the right 'not to know' in true-positive cases. However, in mental health care users, self-reported psychotic experiences may be a useful screening tool in individuals who have already developed help-seeking.
Adult↗
Epidemiological analysis of alcohol and drug use as risk factors for psychotic experiences.
Clinical and laboratory studies link alcohol and other drug use to the occurrence of psychotic experiences, but epidemiologic evidence has been lacking. In this study, the quantitative relationships between alcohol or other drug use and psychotic experiences were examined by analysis of prospective data from 4994 adult household residents sampled in a multisite survey of mental disorders in the population, the NIMH Epidemiologic Catchment Area Program. After control for sociodemographic factors and preexisting psychiatric conditions, the risk for onset of self-reported delusions or hallucinations was observed to be greater for daily users of marijuana or cocaine and for users of anxiolytics or sympathomimetics compared with nonusers. After control for daily cocaine use and alcohol disorder, the risk of onset of psychotic experiences for daily users of marijuana was double that for nonusers. Alcohol disorder in men was associated with eightfold risk and in women with threefold risk. Baseline depressive episodes, manic episodes, agoraphobia, and obsessive-compulsive disorder also were associated with increased risk of onset of psychotic experiences.
Alcoholism↗
Hemispheric lateralization patterns and psychotic experiences in healthy subjects.
The hypothesis that psychotic experiences in healthy subjects are associated with a dysfunction of the right hemisphere is supported by some, but not all, available studies. Differences in gender composition of study samples may explain in part the divergent findings. The present study was carried out in 42 healthy, right-handed university students. Scores on the Schizophrenia and Paranoia scales of the Minnesota Multidimensional Personality Inventory-2 were used in correlation analyses and to define a High- and a Low-Psychotic group. Brain Electrical Microstates and Low Resolution Electromagnetic Tomography (LORETA) source analyses of the auditory P300 (P3a and P3b) components of the event-related potential, as well as a battery of neuropsychological tests, were used to assess hemispheric functioning. Scores on the Paranoia scale were positively associated with a leftward shift of the P3a topographic descriptors in females but not in males. When comparing High-Psychotic and Low-Psychotic females, a leftward shift of P3a descriptors and an increased cortical activation in left fronto-temporal areas were observed in the High-Psychotic group. Our results demonstrated gender-related differences in the pattern of hemispheric imbalance associated with psychotic experiences in healthy subjects.
Adult↗
The importance of subjective psychotic experiences: implications on psychiatric rehabilitation of people with schizophrenia.
Starting with Jaspers in 1910, subjective psychotic experiences of people with schizophrenia became an important area in treatment and rehabilitation of people with schizophrenia. Nevertheless, this area of study is overshadowed by the statistically and diagnostically oriented DSM movement. In this article, the writer tries to re-visit various approaches in understanding subjective psychotic experiences of people with schizophrenia. It seems that subjective psychotic experiences represent persons' inner feelings; their spontaneous struggle in their process of treatment and rehabilitation. All these experiences are meaningful for the persons with psychiatric disabilities. In this paper, the writer tries to show that empathetic understanding of subjective experience can help individuals to re-establish a meaningful relationship with people with schizophrenia and motivate them to become involved in their own rehabilitation process.
Humans↗
LSD: the varieties of psychotic experience.
The varieties of psychotic LSD experiences are many. A very few may resemble a delirium, some are quite reminiscent of schizophrenia and others have an idiosyncratic quality not seen in the naturally occurring psychoses. The psychotic response to LSD is better understood than transcendent experiences because its neurochemistry and phenomenology have been worked out. Additionally, there is greater familiarity with the endogenous psychoses than the endogenous cosmic experiences. The LSD condition, especially the unsane state, is indeed an experience in search of an explanation. It is doubtful that an animal model for it will be found. It is even possible that not all humans are capable of achieving that state by means of the hallucinogenic drugs. The LSD state remains an area of enormous interest that requires exploration and research.
Humans↗
[Recalling the acute psychotic experience].
In this study we have analysed the memory of the acute psychotic experience in chronic schizophrenics to evaluate the influence of memory on present symptomatology. We briefly examine the literature on this subject, then we describe some clinical cases trying to give a sense to the different way of "recovery", in schizophrenics. In particular we note that sensorial events of the acute psychotic experience have an important role in memory. Besides this study deepens some particular aspects of memory in schizophrenics.
Chronic Disease↗
Deconstructing the familiality of the emotive component of psychotic experiences in the general population.
OBJECTIVE: Genetic and environmental influences on variation in distress associated with subclinical psychotic experiences were examined. METHOD: A total of 289 twin pairs filled in the Community Assessment of Psychic Experiences, a self-report instrument assessing subclinical positive and negative psychotic experiences and associated distress (distresspos and distressneg). Using structural equation modelling, univariate and bivariate models were fitted. RESULTS: Univariate model fitting showed genetic and non-shared environmental influences on both distresspos and distressneg. Bivariate model fitting showed that 52% of the correlation between the two phenotypes (r=0.46) was because of shared genes and that non-shared environmental factors accounted for 48% of the correlation. CONCLUSION: Liability to psychosis not only refers to the development of psychosis per se, but also to the liability to develop dysfunctional emotional appraisals. The emotive component of psychosis liability involves genetic transmission of a general, non-symptom-specific distress factor that may be a target for molecular genetic research.
Adolescent↗
What do psychotic experiences mean for young men? A qualitative investigation.
This study is of a grounded theory analysis of the transcripts of young men talking about their experience of psychosis. Six young men were interviewed twice during the critical period of 3-5 years following their first psychotic episode. The young men were asked to reflect on themselves and their lives before, during, and after having psychotic experiences. The transcripts were considered to have a phenomenological status, in that they represented the participants' perspectives on their experiences. Four themes emerged that were common to all the accounts: experience of psychosis, immediate expression of psychotic experiences, personal and interpersonal changes, and personal explanations. These themes are explored in detail, and their links with existing research and clinical implications are considered.
Adult↗
Validity and reliability of the CAPE: a self-report instrument for the measurement of psychotic experiences in the general population.
OBJECTIVE: General population longitudinal cohort studies have demonstrated the prognostic validity of self-reported psychotic experiences, but data on reliability and cross-validation with interview-based measures of these experiences are sparse. This study tested the reliability and validity of the Community Assessment of Psychic Experiences (CAPE42). METHOD: At baseline, the CAPE42 was used to measure the subclinical psychosis phenotype in a general population sample (n = 765). At follow-up (mean interval: 7.7 months), the Structured Interview for Schizotypy, Revised (SIS-R), the Brief Psychiatric Rating Scale (BPRS), and the CAPE42 were administered (n = 510). RESULTS: Baseline self-reported dimensions of psychosis were specifically and independently associated with their equivalent interview-based dimension at follow-up (standardized effect sizes of 0.4-0.5) and with their equivalent self-reported measure (standardized effect sizes of 0.6-0.8). CONCLUSION: The results indicate that self-reported dimensions of psychotic experiences in general population samples appear to be stable, reliable and valid.
Adolescent↗
A study of the link between food-water insecurities and self-reported psychotic experiences among young adults in Gaza Strip: What role does social support play under conditions of war and extreme suffering?
BACKGROUND: The war in Gaza, coupled with severe restrictions on humanitarian access and assistance, have led to a rapid and large-scale exacerbation of food insecurity (FI) and water insecurity (WI) in Gaza, which can cause a myriad of deleterious effects on both physical and mental health. Previous evidence suggests that environmental stressors (such as FI and WI), coupled with lack of support, can compromise coping ability and trigger psychosis. Elucidation of these pathways can inform efforts to reduce the incidence of psychosis in war settings in particular, and in global communities more generally. This study aimed to assess the mediating role of social support on the association between food-water insecurities and psychotic experiences (PEs). METHODS: This study was carried-out over a period of one month (September 2024) by using a free online form builder. Data were collected at a single time point using snowball sampling. A total of 476 adults aged 18–35 years and living in Gaza at the time of the survey took part in this study. The Prodromal Questionnaire- Brief, the Food Insecurity Experience Scale, the Four-Item Household Water Insecurity Experiences Scale, and the Single Item Measure of Social Supports have been administered to participants. RESULTS: A total of 110 participants (23.1%) reported low tangible social support (i.e., having no or 1 person in the social support network), 27.3% were classified as moderately-to-severely food insecure and 41% were categorized as water-insecure. The mediation analysis was adjusted for the following covariates: marital status, living arrangement and age. Higher food-water insecurity experiences were significantly associated with lower social support. Higher food-water insecurity experiences were also significantly associated with higher PEs. Higher social support was significantly associated with lower PEs. The results of the mediation analysis showed that social support mediated the link of FI (indirect effect: Beta = 0.06; Boot SE = 0.03; Boot CI 0.01; 0.12) and WI (indirect effect: Beta = 0.04; Boot SE = 0.02; Boot CI 0.01; 0.08) to PEs. CONCLUSION: Our findings support the case for bolstering social support networks in war-affected communities facing survival challenges such as FI and WI. This study points to the urgent need for increased food aid and improved water supplies in the short term, and sustainable food and water systems in the long term, to support mental health. In times of war, mental health prevention and interventions strategies might do well to increase social support and resources in order to help buffer such intense environmental stressors and prevent the emergence of psychosis. CLINICAL TRIAL NUMBER: Not applicable.
Humans↗
Psychotic experience and disordered thinking: a reappraisal from new perspectives.
The reports of a person suffering from loose associations and disordered behavior serve as the basis for a phenomenology of some central components of psychotic experience. Especially salient are "the expansion of the horizon of meanings," "the emergence of explicit experiences from implicit ones," and "the reduction of complexity." The phenomenological concepts thus developed supplement recent discoveries in neuroscience and experimental psychopathology. Cognitive neuroscientists have depicted the surface of the brain as a repository of self-organizing cortical maps of mental life. Furthermore, experimental psychopathologists have characterized semantic associative networks in normal experience and in psychosis. The authors conclude by joining the phenomenology of psychotic consciousness with the findings of these neuroscientists and experimental psychopathologists.
Adult↗
Event attributes and the content of psychotic experiences in first-episode psychosis.
BACKGROUND: Previous psychosocial stress research, contemporary cognitive models, and new cognitive behavioural treatments for psychosis converge in suggesting that stressful events influence the content of psychotic experiences. In this paper we test whether the attributes of stressful events preceding the initial onset of psychosis are associated with core themes of the illness. METHOD: Forty-one people who had experienced a first episode of psychosis were assessed on the attributes of stressful events occurring in the year before onset, the themes (persecutory, depressive, and grandiose) associated with their delusions and the content of their auditory hallucinations. RESULTS: Principal component analysis yielded four components accounting for 72% of the variance. As hypothesized, intrusive events were associated with the development of delusions with persecutory themes. Grandiose delusions were negatively associated with loss events. Depressive delusions appear to be associated with danger events rather than loss events. CONCLUSION: There are links between stressful event attributes and core psychotic themes at first-episode psychosis. This has implications for theoretical models of, and early psychological intervention for, psychosis.
Adult↗