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At least 19 recordsLinked to original sources

Brief report: progress reported in three children with autism using daily life therapy.

These observational data reflect the school's emphasis in its first few years. Through sharing these results with colleagues at the school and others familiar with the curriculum, additional informal validity was achieved. From this study, it stands out that several important areas of Daily Life Therapy are worthy of greater attention. There is a need to continue observing the progress of children enrolled. Long-term learning in the areas of academics, behavior, and language has not yet been studied. If, indeed, it takes several years to induce changes in the biobehavioral states of children with autism, then these three children should experience an increase in skill acquisition over the next few years. However, the lack of progress in the area noted was disturbing at the time of data collection. These observational results vary tremendously with the type of evaluation and progress reports which are standard procedure as part of the Daily Life Therapy program. In Tokyo, Kitahara had developed her own method of evaluating students, a form called "Standards to Measure the Degree of Autism." At the time of this study, this was still used with each entrant to the school. Japanese and American educators at the school might disagree with the analytic and behavioral style of observations used in this study. Trying to evaluate progress in a Japanese style school using American behavioral procedures was a complicated undertaking, one deserving a more complete review. Some of these intercultural differences are examined elsewhere in an article written collaboratively by a group of American and Japanese educators (Gurry et al., 1996). This study indicates that Daily Life Therapy may have some strengths which are worthy of educators' attention. Educators need to know which treatment might be expected to influence maintenance and generalization as well as acquisition of skills in particular populations of students in order to effectively and propitiously manipulate instructional elements (Donellan & Mirenda, 1983). When making a decision about where to educate children with autism, parents and professionals in the United States and internationally deserve the most complete and honest data. Only then can parents make well-informed decisions about the best educational program for their child.

Adaptation, Psychological↗

Partial amino acid sequences of organ of Corti proteins OCP1 and OCP2: a progress report.

Progress in amino acid sequencing of two low-molecular weight acidic proteins of unknown function which are present at high concentrations in the organ of Corti is reported. These two proteins, provisionally termed OCP1 and OCP2, were originally demonstrated by two-dimensional polyacrylamide gel electrophoresis; their presence at high concentrations in the inner ear sensory epithelia strongly suggests that OCP1 and OCP2 serve some important function in the ear. In the present paper, extension of the amino-terminal sequence of OCP2 to 71 residues is described. In addition, the first results on sequencing of OCP1 are presented. Computer algorithms are used to predict important structural features, and the sequences are analyzed for probable phosphorylation, glycosylation, and Ca-binding sites. Projected further studies in immunochemistry and molecular biology of OCP1 and OCP2 based on the amino acid sequencing data are discussed.

Amino Acid Sequence↗

The Frontlines of Medicine Project progress report: standardized communication of emergency department triage data for syndromic surveillance.

This article reports progress since the original publication of the Frontlines of Medicine Project. This project is a collaborative effort of emergency medicine (including emergency medical services and clinical toxicology), public health, other government agencies involved in health care and preparedness, law enforcement, and informatics to develop nonproprietary, standardized methods for reporting emergency department patient data. These data may be used for a variety of public health or clinical care initiatives, including syndromic surveillance for chemical and biological terrorism. This article reviews the outcome of the Project meeting in April 2002. Also, the article describes a Delphi Survey process to define the data elements in a triage surveillance report and to define a set of codified values for the chief complaint data element. An initial retrospective validation of the codified chief complaint values is provided, and prospective study of the proposed Frontlines' standards is encouraged.

Bioterrorism↗

The International Classification for Nursing Practice: a progress report.

This paper will review and report progress on the development of the International Classification for Nursing Practice. This project, begun in 1990 by the International Council of Nurses, aims to develop a standardised vocabulary and classification of nursing phenomena (nursing diagnoses), nursing interventions, and nursing outcomes which can be used in both electronic and paper records to describe and compare nursing practice across clinical settings. An Alpha Version of the Classification of Nursing Phenomena and Nursing Interventions was released for further development and field testing in 1996 and an outline for a Classification of Nursing Outcomes in 1997. Nurses around the world, and other classification experts, have been invited to participate in the development of the Beta Version which it is hoped will be ready for release in 1999.

Classification↗

The National Large Bowel Cancer Project: a progress report.

The progress report from the National Large Bowel Cancer Project updates the state of the art of investigations concerning causes, role of animal models, early diagnosis of disease including potential biochemical markers, genetic and pharmacological consideration, proventive measures, and new approaches to the treatment of large bowel cancer. It points out the many interrelations in the multidisciplinary approaches to understanding the mechanisms of disease, means of prevention, methods of earlier diagnosis, and development of rational approaches in the control of large bowel cancer.

Animals↗

Randomized, double-blind, placebo-controlled international clinical trial of the Ampakine CX516 in elderly participants with mild cognitive impairment: a progress report.

This progress report briefly describes the rationale and study design for the first cross-national clinical study of a positive AMPA-type glutamate receptor modulator in subjects with mild cognitive impairment (MCI). The study medication for the double-blind, placebo-controlled trial, the AMPAKINE CX516, represents a novel pharmacological approach to the treatment of memory disorders. Previous preclinical and pilot clinical studies have shown that CX516 has the ability to enhance memory and cognition. Design of the trial, including outcome measures and inclusion criteria, was aided by an international panel of experts in the newly emerging field of MCI.

Aged↗

Advanced detection of viral nucleic acids in the central nervous system: a progress report.

A progress report. We have helped to standardize an advanced in situ hybridization technology to detect viral nucleic sequences in formalin fixed paraffin embedded brain tissue with high sensitivity and specificity as well as good preservation of cytomorphology. It is our belief that if the inflammation in the multiple sclerosis central nervous system is associated with persistent virus this technique should reveal it. Technical reasons are given why we are continuing to search for measles virus in multiple sclerosis brain tissue.

Base Sequence↗

Diagnostic markers in human neurooncology. A progress report.

In this progress report, some of the most commonly used antibodies are discussed in regard to their immunohistochemical application to human neurooncology. The importance of determining the spectrum of antibody immunoreactivity in a wide panel of normal, reactive, and neoplastic tissues is stressed. in atypical and aberrant cases, immunopositivity needs to be interpreted with caution and in the context of all other available data. The demonstration of a well-characterized, cell type-specific marker in a tumor reflects not so much its cytogenesis as its differentiation potential and its capacity for metaplasia. The relation of an abnormal or aberrant expression of antigenic determinants to the process of neoplasia raises a number of intriguing questions to which research in the next few years will likely provide answers.

Antigens, Differentiation↗

Preventive cardiology: a progress report.

The progress to the current era of preventive cardiology covers a period of more than 40 years, beginning with epidemiological studies on coronary heart disease and other forms of atherosclerotic disease and related factors and progressing through prevention trials and community demonstration projects to the actual implementation of preventive measures by combined population and high-risk strategies. The scientists of the United States have played a leading role in the data collection which forms the scientific basis for preventive cardiology and the fruitful collaboration in the United States between the scientists and governmental, as well as nongovernmental, organizations in the implementation of preventive cardiology has served as a good example for other countries. The Section on Epidemiology and Prevention of the International Society and Federation of Cardiology and the Cardiovascular Diseases Unit of the World Health Organization, working in close liaison, have had key roles in the worldwide promotion of preventive cardiology. The rapid progress in preventive cardiology during the past 4 years, since the 1st International Conference of Preventive Cardiology, has been dominated by a "snowballing" movement toward more intensive application of cholesterol-lowering measures at both the population and the individual level. Promising progress has also been made in the field of nonpharmacological control of elevated blood pressure.

Adult↗

Meeting Report: 10 Years of Progress: Report from Selected Presentations at the 19th ECTRIMS Congress, 1720 September 2003, Milan, Italy.

The success of the European Committee for Treatment and Research in Multiple Sclerosis (ECTRIMS) is notable, and Chris Polman (Amsterdam, the Netherlands), the new President of ECTRIMS, pointed out that the Congress had grown from an attendance of 50 delegates in 1982 to over 3000 at this 19th meeting. ECTRIMS 2003 provided an overview of recent achievements in clinical multiple sclerosis (MS) research, with sessions highlighting understanding and promoting functional and structural recovery, and the necessity and progress made in co-ordinating research efforts in MS. The impact of molecular biology, new perspectives in MRI and advances in treatment were covered in comprehensive reviews and original presentations. Five hundred stimulating posters from researchers around the world were also presented. Several satellite symposia, a young scientific investigators' session, an international workshop on remyelination in MS, a comprehensive exhibition and presentations of late-breaking research complemented the main programme.

Biomedical Research↗

Intraoperative progress reports decrease family members' anxiety.

The researcher used a four-group quasi-experimental posttest design to examine the effect of intraoperative progress reports on 200 family members' anxiety. Group one (ie, control group) received standard perioperative care, which did not include intraoperative progress reports. Group two received in-person progress reports from perioperative nurses. Group three received an "attention" protocol (ie, checklist explaining hospital routines, waiting room procedures). Group four received progress reports delivered by telephone. The researcher compared family members' state anxiety scores, mean arterial pressures (MAPs), and heart rates measured halfway during their relatives' surgical procedures, measuring these dependent variables after providing the interventions. The in-person intraoperative progress report group reported lower state anxiety scores (P < .001) and had significantly lower MAPs and heart rates (P < .05) than the other three groups. In-person progress reports appear to be the most beneficial perioperative nursing intervention for reducing family members' anxiety during the intraoperative waiting period.

Adolescent↗

Should it be parietal cell vagotomy or selective vagotomy-antrectomy for treatment of duodenal ulcer? A progress report.

This is a progress report of a prospective, randomized study involving 200 consecutive patients treated electively with either parietal cell vagotomy (PCV) or selective vagotomy and antrectomy (SV-A). Both groups comprised patients with pyloric, prepyloric, or duodenal ulcers. There was no operative mortality in either group. Patients were examined at 2, 6, 12 months, and every 12 months thereafter for 8-10 years. The two operations produced no statistical difference in the frequency of diarrhea. Dumping (p less than 0.0005) and weight loss (p less than 0.0005-p less than 0.05) were statistically less after PCV than after SV-A. There were two recurrent ulcers (2.2%) after SV-A. One was treated successfully by medical therapy and one patient suspected of having gastrinoma had total vagotomy. Nine patients had recurrent ulcers in the PCV group for an accumulated recurrence rate of 10.1% at 10 years by life-table analysis. There was a significant difference (p less than 0.033) between the curves for recurrent ulcers in the two groups of patients. The recurrent ulcer rate after PCV was 21% for patients with pyloric and prepyloric ulcers and 6% for patients with duodenal ulcer. There was no significant difference between the recurrent ulcer rate for PCV and SV-A if the patients with pyloric and prepyloric ulcers were withdrawn from the study. Of the nine patients with recurrent ulcers in the PCV group, three had an inadequate vagotomy and four had a pyloric or prepyloric ulcer before operation. Three patients were successfully treated with antrectomy. Five patients were treated successfully by medical therapy and remained healed for long periods without recurrence. One patient had five recurrences. He declined operation and remained free of symptoms for 3 years after his last recurrence. Poor gastric emptying necessitated gastroenterostomy in five patients in the SV-A group and in one patient in the PCV group. Patients' clinical results were evaluated according to a simple Visick grading scale. A significantly (p less than 0.0005) greater number of patients were in Visick I category after PCV than after SV-A. The clinical results obtained with PCV make this the operation of choice for the elective surgical treatment of duodenal ulcers even though the results obtained with SV-A were good.

Adult↗

Prospective randomized study of coronary artery bypass surgery in stable angina pectoris: a progress report on survival.

This progress report on the prospective randomized study of the effect of coronary bypass surgery on prognosis presents the results of a minimum follow-up of 4 years. Seven hundred sixty-eight patients were recruited; all were men younger than age 65 years who had mild-to-moderate angina pectoris, at least two-vessel disease, and good left ventricular function. Of these, 373 were randomized to medical treatment and 395 to surgical treatment. Although 83 "medical" patients subsequently underwent surgery and 27 "surgical" patients did not undergo surgery, these patients were not excluded from the analysis, and the group randomized to coronary bypass surgery was compared with the group randomized to medical treatment. The surgical treatment group showed significantly better survival than the medical treatment group in the total patient population (p less than 0.001), particularly among patients with three-vessel disease (p less than 0.001). Although the 24% higher survival among surgical patients with left main coronary artery disease failed to reach statistical significance, the trend is probably meaningful. No significant difference in survival between medical and surgical treatment groups was noted in patients with two-vessel disease.

Aged↗

Studies in otitis media: Children's Hospital of Pittsburgh-University of Pittsburgh progress report--2004.

OBJECTIVES/HYPOTHESIS: The present Progress Report has summarized the key otitis media clinical trials and laboratory studies conducted since 1969 by investigators at the Children's Hospital of Pittsburgh-University of Pittsburgh (Pittsburgh, PA). STUDY DESIGN: Review. METHODS: Included in the discussion are the following: 1) studies of the epidemiology and risk factors; 2) anatomy and pathology of the eustachian tube-middle ear from human temporal bone histopathological specimens; 3) physiology and pathophysiology of the eustachian tube-middle ear in humans and animal models; 4) pathogenesis; 5) otitis media in special populations (e.g., patients with cleft palate, Native Americans, patients with Down syndrome); 6) microbiology; 7) diagnosis; 8) outcomes of randomized clinical trials that evaluated efficacy of nonsurgical and surgical methods of treatment and prevention; 9) studies of certain complications and sequelae (e.g., effect of middle-ear effusion on hearing, early child development, and the vestibular system; chronic suppurative otitis media). Also included are relevant summary tables and 256 references.

Adenoidectomy↗

Effects of noinionizing radiation on the central nervous system, behavior, and blood: a progress report.

This paper presents a progress report on the U. S. research which has been designated as collaborative research with the Soviet Union to study the biological effects of nonionizing radiation on the central nervous system, behavior, and blood. Results of investigations to study the effects of microwaves on isolated nerves, synaptic function, transmission of neural impulses, electroencephalographic recordings, behavior, and on chemical, cytochemical and immunological properties of the blood are presented. Specifically, the effects of microwave exposure on chick brain and cat spinal cords, on EEG patterns of rats, on behavioral of neonatal rats exposed during development, on behavior of adult rats, on behavior of rhesus monkeys and on the pathology, hematology, and immunology of rabbits will be reported in a summary format. Much of the information is new and has not been published previously.

Action Potentials↗

A national progress report on diabetes: successes and challenges.

Over the last few decades, numerous public health agencies and other private and public organizations have sought to prevent and delay the disabling complications of diabetes by increasing the use of preventive care practices and reducing risk factors for complications among people with diabetes. Now, federal diabetes surveillance activities are yielding encouraging reports that progress is being made in increasing the use of preventive care practices, reducing risk factors for complications, and preventing or delaying diabetes complications. However, although several gains have been noted, levels of preventive care practices remain suboptimal, risk factors for diabetes complications are too prevalent, and diabetes complications are too pervasive. Furthermore, with compelling evidence that the onset of diabetes can be prevented or delayed among adults at high risk, prevention of diabetes has become a major new challenge. Additional efforts are needed to address the growing problems of obesity and physical inactivity, to identify the most efficacious and cost-effective prevention strategies and interventions, and to implement surveillance activities that allow us to gauge our success. Although progress has been made against diabetes complications, the current epidemic of diabetes increases the urgency of primary prevention efforts.

Aged↗